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公开(公告)号:US09720217B2
公开(公告)日:2017-08-01
申请号:US14698532
申请日:2015-04-28
Applicant: Alentic Microscience Inc.
Inventor: Alan Marc Fine , Peter Hodges Gregson
IPC: G02B21/00
CPC classification number: G02B21/0008
Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
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公开(公告)号:US20150241679A1
公开(公告)日:2015-08-27
申请号:US14698532
申请日:2015-04-28
Applicant: Alentic Microscience Inc.
Inventor: Alan Marc Fine , Peter Hodges Gregson
IPC: G02B21/00
CPC classification number: G02B21/0008
Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
Abstract translation: 除其他之外,成像装置具有像素的光敏阵列,并且与阵列相关联的表面被配置为接收样本,其中至少一部分样本与表面的距离相当于小于平均值的大约一半 像素的宽度。
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公开(公告)号:US20250150556A1
公开(公告)日:2025-05-08
申请号:US19008747
申请日:2025-01-03
Applicant: Alentic Microscience Inc.
Inventor: Alan Marc Fine
Abstract: An imaging device includes light sensitive locations that are separately sensitive to light received at a surface with respect to a portion of a sample associated with the surface, the light sensitive locations having a resolution of 5 microns or smaller. There is a device to associate the portion of the sample with the surface. The imaging device and a distance of the portion of the sample to the light sensitive locations are such that usable useful image of the portion of the sample can be acquired directly by operation of the imaging device.
An imaging device can include both the light source locations and the light source locations and the light sensitive locations.-
公开(公告)号:US20230164299A1
公开(公告)日:2023-05-25
申请号:US17981228
申请日:2022-11-04
Applicant: Alentic Microscience Inc.
Inventor: Alan Marc Fine , Hershel Macaulay , Laurent Kreplak
CPC classification number: H04N7/18 , G02B21/0008
Abstract: An imaging device includes light sensitive locations that are separately sensitive to light received at a surface with respect to a portion of a sample associated with the surface, the light sensitive locations having a resolution of 5 microns or smaller. There is a device to associate the portion of the sample with the surface. The imaging device and a distance of the portion of the sample to the light sensitive locations are such that usable useful image of the portion of the sample can be acquired directly by operation of the imaging device.
An imaging device includes light sensitive sources that are separately able to deliver light with respect to a portion of a sample associated with the surface. The light source locations having a resolution of 5 microns or smaller. There is a device to associate the portion of the sample with the surface. The imaging device and a distance of the portion of the sample to the light source locations are such that a useful image of the portion of the sample can be acquired directly by operation of the imaging device.
An imaging device can include both the light source locations and the light source locations and the light sensitive locations.-
公开(公告)号:US11635447B2
公开(公告)日:2023-04-25
申请号:US17103246
申请日:2020-11-24
Applicant: Alentic Microscience Inc.
Inventor: Alan Marc Fine
IPC: G01Q60/20 , G01N21/64 , G02B21/00 , G02B21/36 , H01L27/146
Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
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公开(公告)号:US20220404600A1
公开(公告)日:2022-12-22
申请号:US17712959
申请日:2022-04-04
Applicant: Alentic Microscience Inc.
Inventor: Alan Marc Fine , Peter Hodges Gregson
IPC: G02B21/00
Abstract: Among other things, an imaging device has a photosensitive array of pixels, and a surface associated with the array is configured to receive a specimen with at least a part of the specimen at a distance from the surface equivalent to less than about half of an average width of the pixels.
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公开(公告)号:US11442261B2
公开(公告)日:2022-09-13
申请号:US17193680
申请日:2021-03-05
Applicant: Alentic Microscience Inc.
Inventor: Alan Marc Fine , Joel Ironstone , Christopher Gillespie
Abstract: A base assembly includes an imaging sensor having a sensor surface to receive a sample, and a platform connected to the base assembly. The base assembly includes (a) an aperture configured to receive a lid surface of a lid in a position to define an imaging space between the sensor surface and the lid surface and (b) a movement portion movable toward and away from the base assembly. The platform and the base assembly are configured to limit contact between the sample and the base assembly other than at the sensor surface.
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公开(公告)号:US11061031B2
公开(公告)日:2021-07-13
申请号:US16839752
申请日:2020-04-03
Applicant: Alentic Microscience Inc.
Inventor: Alan Marc Fine
IPC: G01N33/80 , G01N33/569 , G06K9/00 , G02B21/36 , G02B21/00 , G01N15/14 , G01T1/02 , G01B9/02 , G06T7/00 , G03H1/04 , G01N11/00 , G03H1/00 , G01N15/10 , G01N15/00 , C12M1/34
Abstract: Among other things, a method comprises imaging a sample displaced between a sensor surface and a surface of a microscopy sample chamber to produce an image of at least a part of the sample. The image is produced using lensless optical microscopy, and the sample contains at least blood from a subject. The method also comprises automatically differentiating cells of different types in the image, generating a count of one or more cell types based on the automatic differentiation, and deriving a radiation dose the subject has absorbed based on the count.
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公开(公告)号:US20200379234A1
公开(公告)日:2020-12-03
申请号:US16995271
申请日:2020-08-17
Applicant: Alentic Microscience Inc.
Inventor: Alan Marc Fine , Hershel Macaulay , Noah Hymes-Vandermeulen
Abstract: Among other things, a first surface is configured to receive a sample and is to be used in a microscopy device. There is a second surface to be moved into a predefined position relative to the first surface to form a sample space that is between the first surface and the second surface and contains at least part of the sample. There is a mechanism configured to move the second surface from an initial position into the predefined position to form the sample space. When the sample is in place on the first surface, the motion of the second surface includes a trajectory that is not solely a linear motion of the second surface towards the first surface.
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公开(公告)号:US20200292801A1
公开(公告)日:2020-09-17
申请号:US16839752
申请日:2020-04-03
Applicant: Alentic Microscience Inc.
Inventor: Alan Marc Fine
Abstract: Among other things, a method comprises imaging a sample displaced between a sensor surface and a surface of a microscopy sample chamber to produce an image of at least a part of the sample. The image is produced using lensless optical microscopy, and the sample contains at least blood from a subject. The method also comprises automatically differentiating cells of different types in the image, generating a count of one or more cell types based on the automatic differentiation, and deriving a radiation dose the subject has absorbed based on the count.
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