公开(公告)号：US20160101143A1

公开(公告)日：2016-04-14

申请号：US14894210

申请日：2014-04-29

Applicant: DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION ,  CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

Inventor： Choongho LEE ,  Tae Hwe HEO ,  Kee Dong YOON

IPC: A61K36/87

CPC classification number: A61K36/87 ,  A61K2236/33 ,  A61K2236/331 ,  A61K2236/333

Abstract: Provided is a method for preventing or treating hepatitis C by administrating a composition including, as an active ingredient, a Vitidis Vinferae Radix extract or a fraction thereof and, more specifically, to a Vitidis Vinferae Radix extract which is extracted with water and alcohol or a mixed solvent thereof, or a fraction thereof, which have remarkably low hepatotoxicity and exhibit an excellent effect of selectively inhibiting genome replication of a hepatitis C virus, and thus can be useful for preventing or treating hepatitis C.

Abstract translation: 本发明提供一种预防或治疗丙型肝炎的方法，该方法是通过施用包含作为活性成分的维甲蒂提取物或其一部分的组合物，更具体地，涉及一种用水和酒精提取的维生素提取物， 其混合溶剂或其一部分具有显着低的肝毒性，并显示出选择性抑制丙型肝炎病毒基因组复制的优异效果，因此可用于预防或治疗丙型肝炎。

公开(公告)号：US20160032448A1

公开(公告)日：2016-02-04

申请号：US14815797

申请日：2015-07-31

Applicant: Industry-Academic Cooperation Foundation, Yonsei University ,  Incheon University Industry Academic Cooperation Foundation

Inventor： Hyungjun KIM ,  Il-Kwon OH ,  Han-Bo-Ram LEE

IPC: C23C16/06 ,  C23C16/50 ,  C23C16/46 ,  C23C16/455

CPC classification number: C23C16/45525 ,  B08B17/065 ,  C23C16/045 ,  C23C16/40 ,  C23C16/405 ,  C23C16/45555

Abstract: The present disclosure relates to a superhydrophobic coating material and a method for manufacturing the superhydrophobic coating material. The superhydrophobic coating material according to the present disclosure includes a substrate provided with a three-dimensional nano structure; and a coating layer comprising a rare earth metal oxide formed on the three-dimensional nano structure. The method for manufacturing the superhydrophobic coating material according to the present disclosure includes preparing a substrate provided with a three-dimensional nano structure; and forming a coating layer comprising a rare earth metal oxide on the three-dimensional nano structure by supplying a precursor including a rare earth metal and an oxidant one by one onto the substrate, and the temperature of the substrate is controlled in the forming step so that an atomic ratio of a carbon element in the coating layer is less than 1% to form the coating layer with superhydrophobic property.

Abstract translation: 本发明涉及超疏水涂层材料和制造超疏水涂层材料的方法。 根据本公开的超疏水涂料包括具有三维纳米结构的基材; 以及包含在三维纳米结构上形成的稀土金属氧化物的涂层。 根据本公开的制造超疏水涂层材料的方法包括制备具有三维纳米结构的基底; 并通过将包含稀土金属和氧化剂的前体一个接一个地提供到基板上，在三维纳米结构上形成包含稀土金属氧化物的涂层，并且在成形步骤中控制基板的温度 涂层中碳元素的原子比小于1％以形成具有超疏水性的​​涂层。

公开(公告)号：US09050301B2

公开(公告)日：2015-06-09

申请号：US14493375

申请日：2014-09-23

Applicant: Chung-Ang University Industry-Academy Cooperation Foundation ,  Chungbuk National University Industry-Academic Cooperation Foundation ,  Industry Academic Cooperation Foundation, Hallym University

Inventor： Jae Chan Kim ,  Kyoung Woo Kim ,  Yeoun Sook Chun ,  Soo Hyun Park ,  Sung Wook Wee ,  Soo Ik Chang ,  Kyong Mi Min ,  Kyu Wan Kim ,  Young Joo Shin

IPC: A61K38/18 ,  A61K38/46 ,  C07K14/515

CPC classification number: A61K38/1891 ,  A61K38/465 ,  C07K14/515 ,  C12Y301/27008

Abstract: Provided is a pharmaceutical composition for treating corneal endothelium wounds, the composition including angiogenin as an effective ingredient. The present invention relates to a new topical therapeutic use of angiogenin for treatment of corneal endothelium wounds, wherein the angiogenin that is generally known to be involved in angiogenesis activates a PI3K/Akt/eNOS pathway thereof in ocular corneal endothelium to increase migration and proliferation of corneal endothelial cells that are not capable of self-proliferation and to promote prevention and treatment of corneal endothelial cell wounds.

Abstract translation: 本发明提供一种用于治疗角膜内皮伤口的药物组合物，该组合物包含血管生成素作为有效成分。 本发明涉及用于治疗角膜内皮创伤的血管生成素的新的局部治疗用途，其中通常已知参与血管发生的血管生成素在眼角膜内皮中激活PI3K / Akt / eNOS途径以增加角膜内皮细胞的迁移和增殖 角膜内皮细胞不能自我增殖并促进预防和治疗角膜内皮细胞创伤。

公开(公告)号：US08924923B2

公开(公告)日：2014-12-30

申请号：US13759179

申请日：2013-02-05

Applicant: Hongik University Industry-Academic Cooperation Foundation ,  Daegu National University of Education Industry-Academic Cooperation Foundation

Inventor： Hyun-seung Son ,  Woo-yeol Kim ,  Robertyoungchul Kim

IPC: G06F9/44 ,  G06F11/36

CPC classification number: G06F11/3684 ,  G06F11/3676

Abstract: Disclosed herein are an apparatus and a method for generating a multi-level test case for testing software from a unified modeling language (UML) sequence diagram (SD) based on a multiple condition control flow graph (MCCFG). The apparatus includes: a UML SD metamodel storing unit storing a UML SD metamodel defined for a model to be converted therein; an MCCFG metamodel storing unit storing an MCCFG metamodel; a model converting unit model-converting the UML SD from which the test case is to be generated according to the UML SD metamodel and the MCCFG metamodel to generate the MCCFG; and a coverage criteria unit converting the MCCFG into a tree structure and then converting the tree structure into test cases according to a selection command.

Abstract translation: 本文公开了一种用于基于多条件控制流程图（MCCFG）从统一建模语言（UML）序列图（SD）生成用于测试软件的多级测试用例的装置和方法。 该装置包括：UML SD元模型存储单元，存储为要在其中转换的模型定义的UML SD元模型; 存储MCCFG元模型的MCCFG元模型存储单元; 模型转换单元模型 - 根据UML SD元模型和MCCFG元模型转换要从其生成测试用例的UML SD以产生MCCFG; 以及覆盖标准单元将MCCFG转换成树结构，然后根据选择命令将树结构转换成测试用例。

公开(公告)号：US20140194500A1

公开(公告)日：2014-07-10

申请号：US13736780

申请日：2013-01-08

Applicant: Kookmin University Industry Academic Cooperation Foundation ,  Dongguk University Industry-Academic Cooperation Foundation

Inventor： Young-Sam Keum ,  Yong-Joo Jeong ,  Mi-Sun Yu ,  Young-Won Chin

IPC: A61K31/352

CPC classification number: A61K31/352 ,  A61K31/353

Abstract: Provided is a method of treating SARS in mammals. The method includes administering a therapeutically effective amount of at least one composition selected from the group consisting of myricetin, scutellarein and a pharmaceutically acceptable salt thereof to a mammal in need of treatment of SARS diseases to suppress the activities of SARS coronavirus helicase.

Abstract translation: 提供了一种治疗哺乳动物SARS的方法。 该方法包括向需要治疗SARS疾病的哺乳动物施用治疗有效量的至少一种选自杨梅素，黄连素及其药学上可接受的盐的组合物，以抑制SARS冠状病毒解旋酶的活性。

公开(公告)号：US20240252773A1

公开(公告)日：2024-08-01

申请号：US18013323

申请日：2022-08-11

Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY- ACADEMIC COOPERATION FOUNDATION ,  INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

Inventor： Young Hoon JOO ,  Hyun Bum KIM ,  Jong Baeg KIM ,  Yo Han JUNG ,  Dae Yeon KOH ,  Min Hyeong KIM ,  Hyun Jun HAN

IPC: A61M16/04 ,  A61B5/00 ,  A61B5/08

CPC classification number: A61M16/0472 ,  A61B5/0816 ,  A61B5/7203 ,  A61B5/7257 ,  A61B5/743 ,  A61M16/0463 ,  A61M2205/18

Abstract: Proposed are a phlegm suction alarm issuing apparatus and a method for a tracheostomy patient which monitor and analyze a respiratory sound of the tracheostomy patient in real time, then check congestion of phlegm, and issue a phlegm suction alarm.

公开(公告)号：US11301717B2

公开(公告)日：2022-04-12

申请号：US16716881

申请日：2019-12-17

Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION ,  Dongguk University Industry-Academic Cooperation Foundation

Inventor： Won Jun Hwang ,  Ho Chul Sin ,  Dong Yi Kim ,  Soo Chul Lim ,  Dae Kwan Ko

IPC: G06K9/62 ,  G06V10/75

Abstract: A method of measuring an interaction force includes: generating feature maps corresponding to a plurality of sequential images; generating pooling maps respectively corresponding to feature map groups including a predetermined number of feature maps among the feature maps; generating attention maps corresponding to the pooling maps; and sequentially receiving feature maps modified based on the attention maps and outputting interaction force information.

公开(公告)号：US20210405067A1

公开(公告)日：2021-12-30

申请号：US17294507

申请日：2019-09-11

Applicant: INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY ,  INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY

Inventor： Gu Seob ROH ,  Jong Youl LEE ,  Kyung Eun KIM ,  Kun Ho LEE ,  Eun-Ae JEONG

IPC: G01N33/68

Abstract: A method for diagnosing mild cognitive impairment according to an embodiment of the present disclosure includes obtaining a sample from a subject to be diagnosed, and measuring a level of tonicity-responsible enhancer binding protein (TonEBP) in the sample by using TonEBP antibody to determine if the measured level of the TonEBP is above a predetermined level. The measuring may further includes measuring a level of lipocalin-2 (LCN2) in the sample by using LCN2 antibody to determine if the measured level of the LCN2 is above a predetermined level.

公开(公告)号：US20210070718A1

公开(公告)日：2021-03-11

申请号：US16961348

申请日：2019-01-10

Applicant: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION ,  INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY ,  GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY ,  SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Jae Sung BAE ,  Hee Kyung JIN ,  Myung Shik LEE ,  Hye Jin LIM ,  Jin Hee AHN ,  Haushabhau Shivaji PAGIRE ,  Min Jae Lee

IPC: C07D263/46

Abstract: The present invention relates to a novel phenylsulfonyl oxazole derivative and a use thereof and specifically, to a compound represented by Chemical Formula 1 in the present specification or a pharmaceutically acceptable salt thereof, and to a use thereof for prevention, treatment, or improvement of neurodegenerative disease.

公开(公告)号：US10918856B2

公开(公告)日：2021-02-16

申请号：US16030863

申请日：2018-07-10

Applicant: INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION ,  Industry-Academic Cooperation Foundation, Yonsei University

Inventor： Sunggu Yang ,  Jong-Hyun Ahn ,  Jejung Kim ,  Wonho Lee ,  Minpyo Kang

IPC: A61N1/05 ,  A61B5/04 ,  A61B5/00 ,  A61N1/36 ,  A61B5/0478

Abstract: A graphene bio-device for electrotherapy, includes: a flexible substrate; An electrode made of graphene on the flexible substrate; and an insulation layer on the graphene electrode; wherein the graphene bio-device comprises electrodes for ground, reference, recording and stimulation, wherein the graphene bio-device is measured corticography with low noise and alleviated seizure signals successfully by imposing electrical stimulation.