公开(公告)号：US20060235028A1

公开(公告)日：2006-10-19

申请号：US11403092

申请日：2006-04-12

Applicant: James Li ,  Lawrence Hamann ,  Zheming Ruan ,  Christopher Cooper ,  Shung Wu ,  Ligaya Simpkins ,  Haixia Wang ,  Akbar Nayeem ,  Stanley Krystek

Inventor： James Li ,  Lawrence Hamann ,  Zheming Ruan ,  Christopher Cooper ,  Shung Wu ,  Ligaya Simpkins ,  Haixia Wang ,  Akbar Nayeem ,  Stanley Krystek

IPC: A61K31/4965 ,  A61K31/506 ,  A61K31/497 ,  A61K31/4439 ,  A61K31/426 ,  A61K31/421

CPC classification number: C07D213/70 ,  A61K31/421 ,  A61K31/426 ,  A61K31/4439 ,  A61K31/4965 ,  A61K31/497 ,  A61K31/506 ,  C07D213/71 ,  C07D213/81 ,  C07D213/82 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D405/04 ,  C07D405/14 ,  C07D409/04 ,  C07D413/14 ,  C07D487/04 ,  C07D487/08

Abstract: Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein G, L, Q, Z, R6, R7, and R8 are defined herein.

Abstract translation: 提供了新的化合物，其为11-β-羟基类固醇脱氢酶I型抑制剂。 11-β-羟基类固醇脱氢酶I型抑制剂可用于治疗，预防或减缓需要11-β-羟基类固醇脱氢酶I型抑制剂治疗的疾病进展。 这些新化合物具有以下结构：其立体异构体或前药或其药学上可接受的盐，其中G，L，Q，Z，R 6，R 7和R > 8 在本文中定义。

公开(公告)号：US20060157124A1

公开(公告)日：2006-07-20

申请号：US11315679

申请日：2005-12-22

Applicant: James Li ,  Peter Berkman

Inventor： James Li ,  Peter Berkman

IPC: F16K1/30

CPC classification number: F16K3/085 ,  E03B7/12 ,  Y10T137/698 ,  Y10T137/7668 ,  Y10T137/88054

Abstract: A frost free faucet having a spigot assembly including a drain conduit, a sleeve assembly including an elongated pipe, and a valve assembly. The valve assembly includes a ½ turn valve, a check valve and optionally a pressure relief mechanism. The ½ turn valve includes a rotatable valve element configured with a water passageway and a stationary valve element with one or through holes. The rotatable valve element is circular-shaped and configured with a water passageway in a semicircular portion. The stationary element is a disc shaped configured with one or more through-holes in a semi-circular portion of the stationary valve element. Upon turning the rotatable valve element 180 degrees in a first direction, the water passageway and the one or more through-holes are aligned to an open position and upon turning the rotatable element 180 degrees in a second direction, the water passageway and the one or more through-holes are misaligned to a closed position. Each valve element of the ½ turn valve may be formed from a ceramic material, The check valve is located upstream of the ½ turn valve to prevent the backflow of water from the spigot to the supply line. An optional pressure relief mechanism allows water trapped downstream of the valve assembly to be discharged from the valve assembly.

公开(公告)号：US20060063798A1

公开(公告)日：2006-03-23

申请号：US11272898

申请日：2005-11-14

Applicant: Guixue Yu ,  Jun Li ,  William Ewing ,  Richard Sulsky ,  James Li ,  Joseph Tino

Inventor： Guixue Yu ,  Jun Li ,  William Ewing ,  Richard Sulsky ,  James Li ,  Joseph Tino

IPC: C07D471/02 ,  A61K31/4745

CPC classification number: C07D487/04 ,  C07D231/56 ,  C07D261/20 ,  C07D471/04 ,  C07D513/04

Abstract: Novel heterocyclic aromatic compounds are provided that are useful in stimulating endogenous production or release of growth hormone, said compounds having the general structure of formula I wherein R1, R1′, R2, R3, R4, Xa, Y, Z and n are as described herein. The compounds provided herein are useful in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.

Abstract translation: 提供了可用于刺激生长激素的内源性产生或释放的新型杂环芳族化合物，所述化合物具有式I的通式结构

公开(公告)号：US20050065156A1

公开(公告)日：2005-03-24

申请号：US10940241

申请日：2004-09-14

Applicant: James Li ,  Hannguang Chao ,  Joseph Tino ,  William Ewing

Inventor： James Li ,  Hannguang Chao ,  Joseph Tino ,  William Ewing

IPC: A61K31/503 ,  C07D471/20 ,  C07D487/14

CPC classification number: C07D471/20 ,  A61K31/503

Abstract: A method is provided for treating disorders of gastrointestinal motility which include the steps of administering to a patient in need of treatment of a compound having the structure or a pharmaceutically acceptable salt thereof, a prodrug ester thereof, and all stereoisomers thereof, wherein R1 is selected from alkyl, aryl, cycloalkyl, alkenyl, alkynyl, arylalkyl, heteroaryl, heteroarylalkyl or heterocycloalkyl; Z is selected from —CON(R4)R4a, —SO2N(R4)R4a, —CN, and R4 and R4a are the same or different and are independently selected from hydrogen, alkyl, cycloalkyl, aryl, arylalkyl, heteroaryl, or heteroarylalkyl or R4 and R4a can be joined together to form a heterocycle; R4b is selected from hydrogen, halogen, hydroxyl, CN, OCF3, CF3, CONH2, SONH2, SO2CH3, NHCOCH3 or NHCO2CH3; and Q is a substituted bicyclic heterocycle. New compounds for use in treating disorders of gastrointestinal motility are also provided.

Abstract translation: 提供了一种治疗胃肠蠕动障碍的方法，其包括对需要治疗具有其结构或其药学上可接受的盐的化合物，其前药酯及其所有立体异构体的患者给药的步骤，其中选择R1 烷基，芳基，环烷基，烯基，炔基，芳基烷基，杂芳基，杂芳基烷基或杂环烷基; Z选自-CON（R4）R4a，-SO2N（R4）R4a，-CN，R4和R4a相同或不同，独立地选自氢，烷基，环烷基，芳基，芳基烷基，杂芳基或杂芳基烷基或 R4和R4a可以连接在一起形成杂环; R4b选自氢，卤素，羟基，CN，OCF3，CF3，CONH2，SONH2，SO2CH3，NHCOCH3或NHCO2CH3; Q是取代的双环杂环。 还提供了用于治疗胃肠蠕动障碍的新化合物。

公开(公告)号：US20050023643A1

公开(公告)日：2005-02-03

申请号：US10631380

申请日：2003-07-30

Applicant: James Li ,  Richard Pierson ,  Berinder Brar ,  John Higgins

Inventor： James Li ,  Richard Pierson ,  Berinder Brar ,  John Higgins

IPC: H01L23/482 ,  H01L29/423 ,  H01L29/73 ,  H01L29/732 ,  H01L29/737 ,  H01L27/082

CPC classification number: H01L29/7317 ,  H01L23/4821 ,  H01L23/4822 ,  H01L24/01 ,  H01L29/42304 ,  H01L29/732 ,  H01L29/7371 ,  H01L2924/1305 ,  H01L2924/00

Abstract: A bipolar junction transistor (BJT) requires the fabrication of a BJT structure and of a support post which is adjacent to, but physically and electrically isolated from, the BJT structure. The BJT structure includes a semi-insulating substrate, a subcollector, a collector, a base, and an emitter. Metal contacts are formed on the subcollector and emitter to provide collector and emitter terminals. Contact to the structure's base is accomplished with a metal contact which extends from the top of the support post to the edge of the base nearest the support post. The contact bridges the physical and electrical separation between the support post and the base and provides a base terminal for the device. The base contact need extend over the edge of the base by no more than the transfer length associated with the fabrication process. This results in the smaller base contact area over the collector than would otherwise be necessary, and a consequent reduction in base-collector capacitance. The invention is particularly useful when forming heterojunction bipolar transistors (HBTs), built on a compound semiconductor substrate such as indium phosphide (InP).

Abstract translation: 双极结型晶体管（BJT）需要制造BJT结构和与BJT结构相邻但物理和电隔离的支撑柱。 BJT结构包括半绝缘衬底，子集电极，集电极，基极和发射极。 金属触点形成在子集电极和发射极上，以提供集电极和发射极端子。 与结构基座的接触是通过从支撑柱的顶部延伸到靠近支撑柱的基部边缘的金属接触来实现的。 触点桥接支撑柱和基座之间的物理和电气分隔，并为设备提供基座。 基底接触需要不超过与制造工艺相关联的传输长度在基底的边缘上延伸。 这导致集电极上的基极接触面积比原来需要的更小，从而导致基极 - 集电极电容的降低。 本发明在构建在诸如磷化铟（InP）的化合物半导体衬底上的异质结双极晶体管（HBT）时特别有用。

公开(公告)号：US06475249B1

公开(公告)日：2002-11-05

申请号：US09588178

申请日：2000-06-07

Applicant: Cheng Hsien Hsu ,  Chi Chao Wan ,  Yaw Chung Cheung ,  Yingjeng James Li

Inventor： Cheng Hsien Hsu ,  Chi Chao Wan ,  Yaw Chung Cheung ,  Yingjeng James Li

IPC: H01M404

CPC classification number: H01M8/1004 ,  H01M2300/0082 ,  Y02P70/56 ,  Y10T29/49108

Abstract: A method for manufacturing a membrane electrode assembly of a fuel cell by solvent pretreatment to the electrolyte membrane of the membrane electrode assembly is disclosed. A prepared electrolyte membrane is soaked in alcohol solvent for pre-expanding the electrolyte membrane at first, a catalyst layer is uniformly coated onto at least one side of the pre-expanded electrolyte membrane, and then the electrolyte membrane is dried for evenly shrinking the electrolyte membrane and the catalyst layer. Finally, the electrolyte membrane with catalyst layers is interposed between two gas diffusion electrodes, and the resulting sheet is pressed with heating to form the membrane electrode assembly.

Abstract translation: 公开了一种通过溶剂预处理制造燃料电池的膜电极组件到膜电极组件的电解质膜的方法。 首先将制备的电解质膜浸渍在醇溶剂中以预扩张电解质膜，将催化剂层均匀地涂覆在预发泡电解质膜的至少一侧上，然后将电解质膜干燥以均匀地收缩电解质 膜和催化剂层。 最后，将具有催化剂层的电解质膜介于两个气体扩散电极之间，加热压制得到的片材，形成膜电极组件。

公开(公告)号：US5741540A

公开(公告)日：1998-04-21

申请号：US587168

申请日：1996-01-16

Applicant: Yingjeng James Li ,  Ping Ping Tsai

Inventor： Yingjeng James Li ,  Ping Ping Tsai

IPC: C01G41/00 ,  G01N27/12 ,  B05D5/12

CPC classification number: G01N27/121

Abstract: A method for forming a solid state humidity sensor is disclosed which comprises the steps of: (a) dissolving a tungstate salt into an aqueous solution; (b) adjusting the pH of the aqueous tungstate salt solution to below 8.5; (c) forming one or a pair of electrodes on an insulating substrate; (d) placing the substrate into the pH-adjusted aqueous tungstate salt solution and heating the aqueous solution containing the substrate at temperatures above 70.degree. C. to thereby form a pyrochlore-type crystalline tungsten trioxide film over the electrode or pair of electrodes; and (e) forming another electrode over the pyrochlore-type crystalline tungsten trioxide film if only one electrode is formed during step (c). Alternatively, the pyrochlore-type crystalline tungsten trioxide film can be formed over or between the electrodes by heating the pH-adjusted aqueous tungstate salt solution to cause a precipitation of pyrochlore-type crystalline tungsten trioxide, then screen-printing the pyrochlore-type crystalline tungsten trioxide powder on one or both of the electrodes to thereby form a humidity sensing element. The pyrochlore-type crystalline tungsten trioxide is represented by the general formula of(M.sub.2 O).sub.x WO.sub.3.zH.sub.2 O, in which M is a cation, x is about 0.5, and z, which is the amount of crystalline water contained in said crystal, is typically less than 2.

Abstract translation: 公开了形成固态湿度传感器的方法，其包括以下步骤：（a）将钨酸盐盐溶解在水溶液中; （b）将钨酸氢盐水溶液的pH调节至8.5以下; （c）在绝缘基板上形成一个或一对电极; （d）将基材放入pH调节的钨酸钨酸盐水溶液中，并在高于70℃的温度下加热含有基材的水溶液，从而在电极或电极对上形成烧绿石型结晶三氧化钨膜; 和（e）如果在步骤（c）中仅形成一个电极，则在烧绿石型结晶三氧化钨膜上形成另一个电极。 或者，通过加热pH调节的钨酸钨酸盐溶液使烧绿石型结晶三氧化钨沉淀，然后丝网印刷烧绿石型结晶钨，可以在电极之上或之间形成烧绿石型结晶三氧化钨膜 一个或两个电极上的三氧化二铝粉末，从而形成湿度感测元件。 烧绿石型结晶三氧化钨由通式（M 2 O）x WO 3·zH 2 O表示，其中M为阳离子，x为约0.5，z为所述晶体中所含结晶水的量，通常为 小于2。

公开(公告)号：US20120191528A1

公开(公告)日：2012-07-26

申请号：US13014386

申请日：2011-01-26

Applicant: Eric Theodore Bax ,  Nilanjan Roy ,  James Li

Inventor： Eric Theodore Bax ,  Nilanjan Roy ,  James Li

IPC: G06Q30/00

CPC classification number: G06Q30/02 ,  G06Q30/0242 ,  G06Q30/0274

Abstract: Methods and systems are provided, in an online advertising marketplace including publishers, advertisers and data providers, for allocating or partitioning, or automatically allocating or partitioning, advertiser payment, in connection with a purchase of advertising inventory, between a publisher and one or more data providers. Techniques are provided that seek to efficiently and fairly allocate the payment between the parties, taking into account value provided, such as by utilizing Shapley values. Provided techniques may also include efficiently or optimally integrating, facilitating, selecting or automating connections or arrangements between parties within the marketplace.

Abstract translation: 在包括出版商，广告商和数据提供者在内的在线广告市场中，在发布者和一个或多个数据之间提供用于分配或分区，或自动分配或分割广告客户支付与广告库存的购买有关的方法和系统 提供者 提供的技术旨在有效地和公平地分配双方之间的付款，同时考虑到所提供的价值，例如利用Shapley价值。 所提供的技术还可以包括在市场中有效地或最优化地整合，促进，选择或自动化连接或者各方之间的连接。

公开(公告)号：US20080291094A1

公开(公告)日：2008-11-27

申请号：US12214165

申请日：2008-06-17

Applicant: James Li ,  Jing Jiang

Inventor： James Li ,  Jing Jiang

IPC: H01Q9/04

CPC classification number: H01Q1/2291 ,  H01Q1/242 ,  H01Q1/36 ,  H01Q5/371 ,  H01Q5/40 ,  H01Q9/0464 ,  H01Q9/36 ,  H01Q21/28

Abstract: An antenna system includes first, second, and third antennas that are arranged on a substrate and that include an arc-shaped element having a concave side and a convex side, a conducting element that extends substantially radially from a center of the concave side, and a U-shaped element having a base portion with a center that communicates with the conducting element and two side portions that extend from ends of the base portion towards the concave side.

Abstract translation: 天线系统包括布置在基板上的第一，第二和第三天线，包括具有凹面和凸面的弧形元件，从凹面侧的中心大致径向延伸的导电元件，以及 U形元件，其具有与导电元件连通的中心的基部和从基部的端部朝向凹侧延伸的两个侧部。

公开(公告)号：US07238020B2

公开(公告)日：2007-07-03

申请号：US10735754

申请日：2003-12-16

Applicant: Jefferson Y S Yang ,  Yingjeng James Li

Inventor： Jefferson Y S Yang ,  Yingjeng James Li

IPC: F23D11/44

CPC classification number: H01M8/04208 ,  F17C11/005 ,  H01M8/04216 ,  H01M8/0656 ,  Y02E60/321 ,  Y02E60/324 ,  Y02P90/45

Abstract: A control device for controlling hydrogen flow of a hydrogen storage canister accommodated in a canister containing chamber includes a heating device which is connected to a heating fuel storage tank via a heating fuel supplying pipeline for conveying a heating fuel to a catalyst bed in the canister containing chamber and generating heat by combustion of the heating fuel at the catalyst bed. A blowing device provides an air flow to the canister containing chamber. A controller controls the operation of the heating device and the blowing device in correspondence to a temperature signal detected from an internal space of the canister containing chamber. The controller is coupled with a setting unit for setting various parameters which are stored in a parameter storage unit for controlling the controller.

Abstract translation: 用于控制容纳在罐容纳室中的储氢罐的氢气流的控制装置包括加热装置，其通过加热燃料供应管线连接到加热燃料储罐，用于将加热燃料输送到罐中的催化剂床， 并且通过催化剂床处的加热燃料的燃烧产生热量。 吹送装置向容纳容器室提供空气流。 控制器根据从罐容纳室的内部空间检测到的温度信号来控制加热装置和吹风装置的操作。 控制器与设定单元相连，用于设定存储在用于控制控制器的参数存储单元中的各种参数。