公开(公告)号：US07718399B2

公开(公告)日：2010-05-18

申请号：US10576068

申请日：2004-10-14

Applicant: Sung Youb Jung ,  Jin Sun Kim ,  Se Chang Kwon ,  Gwan Sun Lee

Inventor： Sung Youb Jung ,  Jin Sun Kim ,  Se Chang Kwon ,  Gwan Sun Lee

IPC: C12P21/06 ,  C07K14/00

CPC classification number: C12P21/02 ,  C07K16/00 ,  C07K16/241 ,  C07K2317/55 ,  C07K2319/00 ,  C07K2319/02 ,  C12N15/70

Abstract: A recombinant expression vector capable of expressing and secreting an antibody fragment fused with E. coli thermostable enterotoxin signal sequence derivative or E. coli outer membrane protein A (Omp A) signal sequence in the form of a soluble heterozygote protein is used to mass-produce the antibody fragment by culturing a microorganism transformed with the expression vector in a medium and collecting the antibody fragment secreted from the transformed microorganism into the medium.

Abstract translation: 能够表达和分泌与大肠杆菌热稳定性肠毒素信号序列衍生物或可溶性杂合子蛋白质形式的大肠杆菌外膜蛋白A（Omp A）信号序列融合的抗体片段的重组表达载体用于批量生产 通过在培养基中培养用表达载体转化的微生物并将从转化的微生物分泌的抗体片段收集到培养基中的抗体片段。

公开(公告)号：US20060197493A1

公开(公告)日：2006-09-07

申请号：US10530763

申请日：2003-10-14

Applicant: Jin-Sun Kim ,  Young-Jun Kim

Inventor： Jin-Sun Kim ,  Young-Jun Kim

IPC: H02J7/00

CPC classification number: H02J7/025 ,  H02J7/0031 ,  H02J50/10

Abstract: The present invention relates to a non-contact type battery pack charging apparatus using a magnetic field. In the non-contact type battery pack charging apparatus of the present invention, a main control unit (120) receives input data from a voltage comparison unit (140), a current comparison unit (150), a voltage detection unit (170) and a current detection unit (180), determines whether required conditions are fulfilled, such as whether an object is installed, whether the installed object is a battery pack (200), what the charge capacity of the battery pack (200) is, and whether the charging of the battery pack (200) has been completed, and controls a variable-voltage frequency generation unit (130) to be operated so as to correspond to the required conditions. Accordingly, the charging of the battery pack (200) is performed to correspond to the charging capacity of the battery pack (200) only when the battery pack (200) is installed.

Abstract translation: 本发明涉及使用磁场的非接触型电池组充电装置。 在本发明的非接触型电池组充电装置中，主控单元（120）从电压比较单元（140），电流比较单元（150），电压检测单元（170）和 电流检测单元（180）确定是否满足所需条件，诸如是否安装了对象，所安装的对象是否是电池组（200），电池组（200）的充电容量是什么，以及是否 电池组（200）的充电已经完成，并且控制可变电压频率发生单元（130）以便与所需条件相对应。 因此，仅当安装电池组200时，电池组200的充电才能对应于电池组200的充电容量。

公开(公告)号：US09421244B2

公开(公告)日：2016-08-23

申请号：US13638821

申请日：2011-04-04

Applicant: Dae Jin Kim ,  Min Young Kim ,  Jin Sun Kim ,  Sung Hee Hong ,  Sung Youb Jung ,  Se Chang Kwon

Inventor： Dae Jin Kim ,  Min Young Kim ,  Jin Sun Kim ,  Sung Hee Hong ,  Sung Youb Jung ,  Se Chang Kwon

IPC: A61K38/21 ,  A61K47/48 ,  C07K14/565 ,  C07K19/00

CPC classification number: A61K38/215 ,  A61K47/68 ,  A61K47/6813 ,  A61K47/6835 ,  C07K14/565 ,  C07K19/00 ,  C07K2317/52 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2319/30

Abstract: The present invention relates to a long-acting interferon beta formulation having improved in vivo duration and stability, comprising an interferon beta conjugate that is prepared by covalently linking interferon beta with an immunoglobulin Fc region via a non-peptidyl polymer, and a preparation method thereof. The long-acting interferon beta formulation of the present invention maintains in vivo activity of interferon beta at a relatively high level and remarkably increases the serum half-life thereof, thereby being used for various diseases, for which interferon is efficacious.

Abstract translation: 本发明涉及具有改善的体内持续时间和稳定性的长效型干扰素β制剂，其包含通过非肽基聚合物共价连接干扰素β与免疫球蛋白Fc区制备的干扰素β偶联物及其制备方法 。 本发明的长效干扰素β配方维持干扰素β的体内活性在相当高的水平，并显着提高其血清半衰期，从而被用于干扰素有效的各种疾病。

公开(公告)号：US08483348B2

公开(公告)日：2013-07-09

申请号：US13527788

申请日：2012-06-20

Applicant: Joon Kyoo Park ,  Jin Seok Lee ,  Kyeong Lak Jeon ,  Jung Min Suh ,  Gi-Jun Gwon ,  Nam Gyu Park ,  Kyong Bo Eom ,  Jin Sun Kim ,  Dong Geun Ha ,  Kyoung Joo Kim

Inventor： Joon Kyoo Park ,  Jin Seok Lee ,  Kyeong Lak Jeon ,  Jung Min Suh ,  Gi-Jun Gwon ,  Nam Gyu Park ,  Kyong Bo Eom ,  Jin Sun Kim ,  Dong Geun Ha ,  Kyoung Joo Kim

IPC: G21C1/22 ,  G21C19/28 ,  G21C9/00 ,  G21C23/00 ,  G21C1/04

CPC classification number: G21C3/331 ,  G21C3/3315 ,  Y02E30/40

Abstract: A hold-down spring unit for a top nozzle of a nuclear fuel assembly. The hold-down spring unit is coupled to the upper end of the top nozzle of the nuclear fuel assembly. The hold-down spring unit includes a first spring which provides a hold-down force upon the nuclear fuel assembly under start-up conditions or hot full power conditions of a nuclear reactor, and a second spring which provides an additional hold-down force upon the nuclear fuel assembly under start-up conditions of the nuclear reactor. The hold-down margin under start-up conditions or hot full power conditions is reduced, thus enhancing the mechanical and structural stability of the nuclear fuel assembly.

Abstract translation: 用于核燃料组件的顶部喷嘴的压紧弹簧单元。 压紧弹簧单元联接到核燃料组件的顶部喷嘴的上端。 压紧弹簧单元包括第一弹簧，其在核反应堆的启动条件或热全功率条件下向核燃料组件提供压紧力，以及向第二弹簧提供额外的压紧力 核燃料组件在核反应堆的启动条件下。 在启动条件或热全功率条件下的压紧余量减少，从而提高核燃料组件的机械和结构稳定性。

公开(公告)号：US20120246933A1

公开(公告)日：2012-10-04

申请号：US13524254

申请日：2012-06-15

Applicant: Joon Kyoo Park ,  Jin Seok Lee ,  Kyeong Lak Jeon ,  Jung Min Suh ,  Gi-Jun Gwon ,  Nam Gyu Park ,  Kyong Bo Eom ,  Jin Sun Kim ,  Dong Geun Ha ,  Kyoung Joo Kim

Inventor： Joon Kyoo Park ,  Jin Seok Lee ,  Kyeong Lak Jeon ,  Jung Min Suh ,  Gi-Jun Gwon ,  Nam Gyu Park ,  Kyong Bo Eom ,  Jin Sun Kim ,  Dong Geun Ha ,  Kyoung Joo Kim

IPC: B23P17/00

CPC classification number: G21C3/331 ,  G21C3/3315 ,  G21C21/00 ,  Y02E30/40 ,  Y10T29/494 ,  Y10T29/49432

Abstract: A top nozzle is provided. The top nozzle can include a coupling plate, a perimeter wall and a hold-down spring unit. The coupling plate can be coupled to a guide thimble of the nuclear fuel assembly. The perimeter wall can protrude upwards from the perimeter of the coupling plate. A spring clamp can be provided on the upper surface of the perimeter wall. The hold-down spring unit can be mounted to the upper surface of the perimeter wall in such a way to couple a corresponding end of the hold-down spring unit to the spring clamp. A fastening pin hole can be vertically formed through an upper surface of the spring clamp. A spring insert hole into which the hold-down spring unit can be inserted and formed by electro-discharge machining in an insert direction of the hold-down spring.

Abstract translation: 提供顶部喷嘴。 顶部喷嘴可以包括联接板，周边壁和压紧弹簧单元。 联接板可以联接到核燃料组件的导向套管。 周边壁可以从联接板的周边向上突出。 可以在周壁的上表面上设置弹簧夹。 压紧弹簧单元可以以这样的方式安装到周壁的上表面，以将压紧弹簧单元的相应端部联接到弹簧夹。 紧固销孔可以通过弹簧夹的上表面垂直地形成。 弹簧插入孔，压紧弹簧单元可以通过放电加工在压紧弹簧的插入方向上插入和形成。

公开(公告)号：US07916825B2

公开(公告)日：2011-03-29

申请号：US11970961

申请日：2008-01-08

Applicant: Shin-ho Lee ,  Yoon-ho Kim ,  Kyou-seok Lee ,  Kyu-Tae Kim ,  Jung-min Suh ,  Nam-Gyu Park ,  Kyong-bo Eom ,  Joon-kyoo Park ,  Jin-sun Kim

Inventor： Shin-ho Lee ,  Yoon-ho Kim ,  Kyou-seok Lee ,  Kyu-Tae Kim ,  Jung-min Suh ,  Nam-Gyu Park ,  Kyong-bo Eom ,  Joon-kyoo Park ,  Jin-sun Kim

IPC: G21C3/00 ,  G21C19/00 ,  F16F1/18 ,  F16F1/20 ,  F16F1/00

CPC classification number: G21C3/18 ,  G21C3/02 ,  Y02E30/40

Abstract: The present invention relates to a fuel rod of a nuclear fuel assembly having a vase-like compression spring adapted to increase the internal volume thereof wherein when the vase-like compression spring is inserted into a cladding tube, it has a relatively smaller volume occupied inside the fuel rod when compared with the existing coil type compression spring, such that the vase-like compression spring can ensure a sufficient space portion receiving the fission gases generated during the operation of the fuel rod, thereby increasing the burn-up performance of the fuel rod and the mechanical integrity thereof.

Abstract translation: 本发明涉及一种核燃料组件的燃料棒，其具有适于增加其内部体积的花瓶状压缩弹簧，其中当花瓶状压缩弹簧插入到包壳管中时，其内部具有相对较小的体积 燃料棒与现有的线圈型压缩弹簧相比，使得花瓶状压缩弹簧能够确保足够的空间部分接收在燃料棒操作期间产生的裂变气体，从而增加燃料的燃耗性能 杆及其机械完整性。

公开(公告)号：US07835484B2

公开(公告)日：2010-11-16

申请号：US11971306

申请日：2008-01-09

Applicant: Kyong-bo Eom ,  Kyu-Tae Kim ,  Jung-min Suh ,  Shin-ho Lee ,  Nam-Gyu Park ,  Joon-kyoo Park ,  Jin-sun Kim ,  Il-kyu Kim ,  Seong-ki Lee ,  Joon-hyung Choi

Inventor： Kyong-bo Eom ,  Kyu-Tae Kim ,  Jung-min Suh ,  Shin-ho Lee ,  Nam-Gyu Park ,  Joon-kyoo Park ,  Jin-sun Kim ,  Il-kyu Kim ,  Seong-ki Lee ,  Joon-hyung Choi

IPC: G21C3/34

CPC classification number: G21C3/352 ,  G21C3/3563 ,  Y02E30/40

Abstract: The present invention relates to an anti-fretting wear spacer grid having a plurality of canoe-shaped springs formed thereon, wherein each of the canoe-shaped springs includes: a fuel rod-contacting part having a flat surface having a predetermined longitudinal length so as to have linear contact with the fuel rod; a curved face-connecting part formed on the upper and lower portions of the fuel rod-contacting part; a leg-connecting part formed on the end portion of the curved face-connecting part; and legs each being formed of a plate shape having a predetermined length and connecting the both sides of the leg-connecting part with one unit grid cell surface.

Abstract translation: 本发明涉及一种具有形成在其上的多个独木舟形弹簧的抗微动磨损间隔栅格，其中每个独木舟形弹簧包括：具有预定纵向长度的平坦表面的燃料棒接触部分， 与燃料棒线性接触; 形成在所述燃料棒接触部的上部和下部的弯曲面连接部; 形成在曲面连接部的端部上的腿连接部; 并且每个腿均由具有预定长度的板形形成，并且将腿连接部分的两侧与一个单元格格单元表面相连。

公开(公告)号：US20090122947A1

公开(公告)日：2009-05-14

申请号：US12187455

申请日：2008-08-07

Applicant: Nam-Gyu PARK ,  Kyu-Tae Kim ,  Jung-Min Suh ,  Shin-Ho Lee ,  Kyong-Bo Eom ,  Joon-Kyoo Park ,  Jin-Sun Kim ,  Gyu-Cheol Shin ,  Seong-Ki Lee ,  Il-kyu Kim ,  Ki-Sung Choi ,  Kyeong-Lak Jeon

Inventor： Nam-Gyu PARK ,  Kyu-Tae Kim ,  Jung-Min Suh ,  Shin-Ho Lee ,  Kyong-Bo Eom ,  Joon-Kyoo Park ,  Jin-Sun Kim ,  Gyu-Cheol Shin ,  Seong-Ki Lee ,  Il-kyu Kim ,  Ki-Sung Choi ,  Kyeong-Lak Jeon

IPC: G21C3/32

CPC classification number: G21C3/334 ,  Y02E30/40

Abstract: Disclosed herein is a joining structure between a top nozzle and guide thimbles in a nuclear fuel assembly, which can prevent a rotation of inner insertion tube bodies when the top nozzle is separated from the nuclear fuel assembly and promote convenience in assembling and disassembling the top nozzle and the guide thimbles.

Abstract translation: 这里公开了一种在核燃料组件中的顶部喷嘴和导向套筒之间的接合结构，当顶部喷嘴与核燃料组件分离时，其可以防止内部插入管体的旋转，并且促进组装和拆卸顶部喷嘴的便利性 和引导套管。

公开(公告)号：US20090104660A1

公开(公告)日：2009-04-23

申请号：US10576068

申请日：2004-10-14

Applicant: Sung Youb Jung ,  Jin Sun Kim ,  Se Chang Kwon ,  Gwan Sun Lee

Inventor： Sung Youb Jung ,  Jin Sun Kim ,  Se Chang Kwon ,  Gwan Sun Lee

IPC: C12P21/04 ,  C12N15/00 ,  C12N1/21

CPC classification number: C12P21/02 ,  C07K16/00 ,  C07K16/241 ,  C07K2317/55 ,  C07K2319/00 ,  C07K2319/02 ,  C12N15/70

Abstract: A recombinant expression vector capable of expressing and secreting an antibody fragment fused with E. coli thermostable enterotoxin signal sequence derivative or E. coli outer membrane protein A (Omp A) signal sequence in the form of a soluble heterozygote protein is used to mass-produce the antibody fragment by culturing a microorganism transformed with the expression vector in a medium and collecting the antibody fragment secreted from the transformed microorganism into the medium

Abstract translation: 能够表达和分泌与大肠杆菌热稳定性肠毒素信号序列衍生物或可溶性杂合子蛋白质形式的大肠杆菌外膜蛋白A（Omp A）信号序列融合的抗体片段的重组表达载体用于批量生产 通过在培养基中培养用表达载体转化的微生物并将从转化的微生物分泌的抗体片段收集到培养基中的抗体片段

公开(公告)号：US20080293106A1

公开(公告)日：2008-11-27

申请号：US12063379

申请日：2006-08-16

Applicant: Sung youb Jung ,  Jin Sun Kim ,  Jin hwan Shin ,  Se-Chang Kwon ,  Gwan-Sun Lee ,  Dae hae Song

Inventor： Sung youb Jung ,  Jin Sun Kim ,  Jin hwan Shin ,  Se-Chang Kwon ,  Gwan-Sun Lee ,  Dae hae Song

IPC: C12P21/00 ,  C07K16/00

CPC classification number: C07K16/00 ,  A61K47/6811 ,  A61K47/6835 ,  C07K2317/41 ,  C07K2317/52

Abstract: Disclosed is a method for the mass production of a monomeric or dimeric immunoglobulin Fc region, free of initial methionine residues, using a recombinant expression vector comprising a nucleotide sequence coding for a recombinant immunoglobulin Fc region comprising an immunoglobulin Fc region linked at the N-terminus thereof to an immunoglobulin Fc region via a peptide bond.

Abstract translation: 公开了使用包含编码重组免疫球蛋白Fc区的核苷酸序列的重组表达载体大规模生产不含初始甲硫氨酸残基的方法，所述重组表达载体包含在N末端连接的免疫球蛋白Fc区 通过肽键与免疫球蛋白Fc区连接。