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公开(公告)号：US20190078117A1
公开(公告)日：2019-03-14
申请号：US15763701
申请日：2016-10-03
Applicant: Keygene N.V.
IPC: C12N15/82 , C07K14/415
Abstract: It was found that plants comprising modified CENPC protein comprising one or more active mutations which affect the functioning of CENPC protein yet allow plants expressing said modified CENPC protein to be viable, are able to induce haploid offspring after a cross to or with a wild type plant comprising a endogenous CENPC protein. The invention relates to generation of haploid and doubled haploid plants.
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公开(公告)号：US20190017065A1
公开(公告)日：2019-01-17
申请号：US16069982
申请日：2017-01-12
Applicant: KEYGENE N.V.
Inventor： Jesse David Munkvold , Anne Deslattes Mays
IPC: C12N15/82
Abstract: The present invention relates to a method for modifying lateral budding in a plant comprising modifying the expression or function of a protein comprising the sequence shown as SEQ ID NO: 3, 4, 5 or a sequence which has at least 70% sequence identity thereto. The invention further relates to plants, plant propagation material, harvested leaf and processed leaf obtainable by such methods.
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公开(公告)号：US10093944B2
公开(公告)日：2018-10-09
申请号：US15610755
申请日：2017-06-01
Applicant: Enza Zaden Beheer B.V. , Keygene N.V.
Inventor： Paul Johan Diergaarde , Leonora Johanna Gertruda van Enckevort , Karin Ingeborg Posthuma , Marinus Willem Prins
IPC: C12N15/82 , C07K14/415
Abstract: The present invention relates to powdery mildew resistance providing genes of the Cucumis family, and especially Cucumis melo, wherein said resistance is provided by impairment of the present genes. Further, the present invention relates plants comprising the present impaired resistance conferring genes and seeds, embryos or other propagation material thereof. Especially, the present invention relates to powdery mildew resistance conferring genes, wherein the amino acid sequence encoded by said resistance conferring gene is selected from the group consisting of SEQ ID No. 2, SEQ ID No. 4, SEQ ID No. 6, SEQ ID. No. 8, SEQ ID No. 10, SEQ ID No. 12 and SEQ ID No. 14, and amino acid sequences with more than 70% identity, preferably more than 80% identity, more preferably more than 90% identity, and most preferably more than 95% identity.
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公开(公告)号：US20180245151A1
公开(公告)日：2018-08-30
申请号：US15961542
申请日：2018-04-24
Applicant: Keygene N.V.
IPC: C12Q1/6874 , G06F19/22 , C12Q1/6855 , C12Q1/6858
CPC classification number: C12Q1/6874 , C12Q1/6806 , C12Q1/6827 , C12Q1/6846 , C12Q1/6851 , C12Q1/6855 , C12Q1/6858 , C12Q1/6869 , C12Q2600/13 , G06F19/22 , C12Q2525/155 , C12Q2563/179 , C12Q2563/155 , C12Q2537/143
Abstract: Efficient methods are disclosed for the high throughput identification of mutations in genes in members of mutagenized populations. The methods comprise DNA isolation, pooling, amplification, creation of libraries, high throughput sequencing of libraries, preferably by sequencing-by-synthesis technologies, identification of mutations and identification of the member of the population carrying the mutation and identification of the mutation.
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公开(公告)号：US20180163222A1
公开(公告)日：2018-06-14
申请号：US15880825
申请日：2018-01-26
Applicant: Keygene N.V.
Inventor： Anne DESLATTES MAYS , Marieke Helena Adriana VAN HULTEN , Shital Anilkumar DIXIT , Martin DE VOS , Jesse David MUNKVOLD , Matthew Vitabile DILEO
Abstract: The present invention relates to a new method for increasing drought resistance of a plant. The method encompasses the impairment of the expression of a gene or genes in said plant. In comparison to a plant not manipulated to impair the expression of said gene(s), the plants display improved drought resistance. Also provided are plants and plant products that can be obtained by the method according to the invention.
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Patent Agency Ranking
公开(公告)号：US09909138B2
公开(公告)日：2018-03-06
申请号：US14377844
申请日：2013-02-18
Applicant: Keygene N.V.
Inventor： Anne Deslattes Mays , Marieke Helena Adriana Van Hulten , Shital Anilkumar Dixit , Martin De Vos , Jesse David Munkvold , Matthew Vitabile Dileo
CPC classification number: C12N15/8273 , C12N15/8218 , C12Y301/01011 , G01N33/0098
Abstract: The present invention relates to a new method for increasing drought resistance of a plant. The method encompasses the impairment of the expression of a gene or genes in said plant. In comparison to a plant not manipulated to impair the expression of said gene(s), the plants display improved drought resistance. Also provided are plants and plant products that can be obtained by the method according to the invention.
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公开(公告)号：US20170247713A1
公开(公告)日：2017-08-31
申请号：US15455294
申请日：2017-03-10
Applicant: Keygene N.V.
CPC classification number: C12N15/8243 , A01H1/02 , A01H1/04 , A01H5/00 , A01H5/12 , C07K14/415 , C12N15/8286 , C12P5/007 , Y02A40/162
Abstract: The present invention relates to identification and isolation of zinc finger transcription factor in tomato that specifically expresses in glandular trichomes of Solanum lycopersicum cultivar Moneymaker and binds to the promoters of the genes encoding Terpene Synthase 5 (also known as Monoterpene Synthase1) and Terpene Synthase 11 (also known as Sesquiterpene Synthase 1). The invention provides the isolated, recombinant or synthetic polynucleotides encoding the polypeptide sequences of SEQ ID NO:2 and variants and fragments thereof. The invention also provides constructs, vectors, host cells and plants genetically modified to contain the polynucleotides of the invention. The methods for producing plants with altered levels of terpenes, including transformed and mutant plants, are also provided.
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公开(公告)号：US20170114405A1
公开(公告)日：2017-04-27
申请号：US15400920
申请日：2017-01-06
Applicant: Keygene N.V.
CPC classification number: C12Q1/6874 , C12Q1/6806 , C12Q1/6827 , C12Q1/6846 , C12Q1/6851 , C12Q1/6855 , C12Q1/6858 , C12Q1/6869 , C12Q2600/13 , G06F19/22 , C12Q2525/155 , C12Q2563/179 , C12Q2563/155 , C12Q2537/143
Abstract: Efficient methods are disclosed for the high throughput identification of mutations in genes in members of mutagenized populations. The methods comprise DNA isolation, pooling, amplification, creation of libraries, high throughput sequencing of libraries, preferably by sequencing-by-synthesis technologies, identification of mutations and identification of the member of the population carrying the mutation and identification of the mutation.
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公开(公告)号：US20160132635A1
公开(公告)日：2016-05-12
申请号：US14898005
申请日：2014-06-13
Applicant: KEYGENE N.V.
Inventor： Jacob Bernhard BUNTJER , José Lúcio Lima GUERRA , Timotheus Gerardus DOESWIJK , Remco VAN BERLOO , Niek BOUMAN
CPC classification number: G16B20/00 , A01H1/04 , A01K67/02 , C12Q1/6876 , C12Q2600/124 , C12Q2600/13 , C12Q2600/156 , G16B40/00
Abstract: The present invention provides a method for improving at least one phenotypic trait of interest in subsequent generation(s) of a population of individuals, preferably crop plants or cattle. Particularly, the method identifies the combination of at least three individuals that gives, upon subsequent intercrossing, the highest estimated probability of improving the at least one phenotypic trait of interest in the subsequent generation(s). Also provided is a computer-readable medium comprising instructions for performing the method.
Abstract translation: 本发明提供一种改善个体群体，优选作物植物或牛的随后一代中至少一种感兴趣的表型性状的方法。 特别地，该方法识别至少三个个体的组合，其在随后的交叉中给出在随后的一代中改善感兴趣的至少一种表型性状的最高估计概率。 还提供了包括用于执行该方法的指令的计算机可读介质。
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公开(公告)号：US20160083788A1
公开(公告)日：2016-03-24
申请号：US14677811
申请日：2014-06-06
Applicant: KEYGENE N.V.
Inventor： René Cornelis Josephus HOGERS
IPC: C12Q1/68
CPC classification number: C12Q1/6874 , C12Q1/6806 , C12Q1/6869 , C12Q1/6855 , C12Q2521/501 , C12Q2525/161 , C12Q2525/191 , C12Q2525/197 , C12Q2525/307 , C12Q2531/125 , C12Q2535/122 , C12Q2537/159 , C12Q2563/179
Abstract: The method of the present invention now provides a technique for generating sequence information from nucleic acid samples based on knowledge from part(s) of the nucleotide sequence. The knowledge of the partial sequence may include knowledge about the presence of restriction sites. The knowledge of the partial sequence can be used to generate adaptor-ligated or nucleotide-elongated fragments. From the combination of information on the ligated adaptor and the Known Nucleotide Sequence Section, probes can be designed. The probes can be used in the provision of circularized fragments that can be sequenced. Combining the known and determined sequences adds sequence information to the already existing sequence information and complements the available genomic sequence information.
Abstract translation: 本发明的方法现在提供了一种基于核苷酸序列的一部分的知识从核酸样品产生序列信息的技术。 部分序列的知识可以包括关于限制性位点的存在的知识。 部分序列的知识可用于产生衔接子连接或核苷酸延伸的片段。 从连接适配器和已知核苷酸序列部分的信息的组合可以设计探针。 探针可用于提供可排序的循环碎片。 结合已知和确定的序列将序列信息添加到已经存在的序列信息中并补充可用的基因组序列信息。
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