Method for coating metal implants with therapeutic mixtures
    13.
    发明授权
    Method for coating metal implants with therapeutic mixtures 有权
    用治疗性混合物涂覆金属植入物的方法

    公开(公告)号:US08765211B2

    公开(公告)日:2014-07-01

    申请号:US13254569

    申请日:2010-03-31

    IPC分类号: A61L33/00

    摘要: Disclosed herein are methods of treating an article surface. The method comprises delivering a polymer and drug to a medical implant having a porous surface and using at least one particle stream from at least one fluid jet to subsequently remove the polymer from the outer surface of the metal substrate, thereby retaining the therapeutic agent and polymer within the pores of the implant.

    摘要翻译: 本文公开了处理制品表面的方法。 该方法包括将聚合物和药物递送到具有多孔表面的医用植入物上,并使用至少一种来自至少一种流体射流的颗粒物流,随后从金属基底的外表面除去聚合物,由此保留治疗剂和聚合物 在植入物的孔内。

    IMPLANTABLE MEDICAL DEVICES
    14.
    发明申请
    IMPLANTABLE MEDICAL DEVICES 有权
    可植入医疗器械

    公开(公告)号:US20120171354A1

    公开(公告)日:2012-07-05

    申请号:US13315902

    申请日:2011-12-09

    IPC分类号: C23C16/50

    摘要: The present invention is directed to methods for producing a coated substrate, including dissolving at least one biomolecule to form a solution; nebulizing the solution to form a liquid aerosol; combining the liquid aerosol and a plasma to form a coating; and depositing, in the absence of reactive monomers, the coating onto a substrate surface. In an aspect, the substrate can be an implantable medical device.

    摘要翻译: 本发明涉及制备涂覆的基材的方法,包括溶解至少一种生物分子以形成溶液; 将溶液雾化形成液体气溶胶; 组合液体气溶胶和等离子体以形成涂层; 并且在不存在反应性单体的情况下将涂层沉积到基底表面上。 在一方面,基底可以是可植入的医疗装置。

    APPARATUS AND METHOD FOR DEPOSITION OF FUNCTIONAL COATINGS
    15.
    发明申请
    APPARATUS AND METHOD FOR DEPOSITION OF FUNCTIONAL COATINGS 审中-公开
    用于沉积功能性涂料的装置和方法

    公开(公告)号:US20120009231A1

    公开(公告)日:2012-01-12

    申请号:US13257072

    申请日:2010-03-18

    摘要: A method for deposition of functional coatings comprises igniting a non-thermal equilibrium plasma within an ambient pressure plasma chamber having a gas supply inlet and a plasma outlet; and providing a substrate to be coated adjacent to the plasma outlet. A gas phase pre-cursor monomer is provided to the plasma chamber through the gas inlet. A specific energy is coupled into the plasma during the flow of the pre-cursor through the chamber sufficient to disassociate at least the weakest intra-molecular bond required to allow polymerisation of the pre-cursor when deposited on a surface of the substrate adjacent the plasma outlet, the coupled specific energy not exceeding a specific energy required break intra-molecular bonds required for the functionality of the monomer molecule.

    摘要翻译: 一种用于沉积功能涂层的方法包括在具有气体供应入口和等离子体出口的环境压力等离子体室内点燃非热平衡等离子体; 以及在等离子体出口附近提供待涂覆的基底。 通过气体入口将等离子体室提供气相前体单体。 在预先通过室的流动期间,将特定的能量耦合到等离子体中,足以使至少最弱的分子内键分离,所述最弱分子键当沉积在邻近等离子体的基板的表面上时允许前标的聚合 出口,耦合比能不超过特定能量,需要破坏单体分子功能所需的分子内键。