公开(公告)号：US20080139915A1

公开(公告)日：2008-06-12

申请号：US11695160

申请日：2007-04-02

申请人： Mark Dolan ,  David Simon

发明人： Mark Dolan ,  David Simon

IPC分类号： A61B5/05 ,  A61F2/06

CPC分类号： A61F2/954 ,  A61B5/06 ,  A61B5/062 ,  A61B5/6859 ,  A61B34/20 ,  A61B2034/105 ,  A61B2034/108 ,  A61B2034/2051 ,  A61F2/07 ,  A61F2002/061 ,  A61F2002/067 ,  A61M2025/0166

摘要： A branch vessel in a human patient is located or mapped using in vivo tracked field sensors where in one variation the sensor positions can be located by determining the positions of the sensors relative to a plurality of magnetic field sources of known location. This approach is used, for example, in locating the opening in a renal artery and positioning the proximal end of the AAA stent-graft adjacent to the opening. In another example, the sensors are tracked along the inner wall of an aneurysm and the acquired sensor location data processed to map the contour of the aneurysm to size a prostheses for spanning the aneurysm. The portions of the vessel adjacent the aneurysm also can be mapped. In a further embodiment, an in vivo sensor is positioned in a deployed prosthesis to create a reference for a prosthetic member having a sensor to track to during cannulation of the deployed prosthesis with the prosthetic member.

摘要翻译： 使用体内跟踪场传感器定位或映射人类患者中的分支血管，其中在一个变化中，可以通过确定传感器相对于已知位置的多个磁场源的位置来定位传感器位置。 例如，该方法用于将肾动脉中的开口定位并将AAA支架移植物的近端定位成与开口相邻。 在另一示例中，沿着动脉瘤的内壁跟踪传感器，并且处理所获取的传感器位置数据以映射动脉瘤的轮廓以使用于跨越动脉瘤的假体尺寸。 邻近动脉瘤的血管部分也可以被映射。 在另一实施例中，体内传感器定位在部署的假体中，以为具有传感器的假体构件创建参考，所述假体构件具有在用所述假体构件插入所展开的假体期间跟踪的传感器。

公开(公告)号：US07377937B2

公开(公告)日：2008-05-27

申请号：US10420553

申请日：2003-04-22

申请人： Mark Dolan

发明人： Mark Dolan

IPC分类号： A61F2/06

CPC分类号： A61F2/07 ,  A61F2/89 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2002/91541 ,  A61F2220/0041 ,  A61F2220/005 ,  A61F2230/0054 ,  A61F2250/0067

摘要： The present invention provides a stent-graft assembly. The assembly comprises at least one stent framework and a graft member. The graft member is positioned adjacent an inner surface of the stent framework and everted over an outer surface of the stent framework to enclose at least a portion of the stent framework. The assembly may further comprise a therapeutic agent that is enclosed by the graft member. Elution openings may be formed in the graft member to preferentially elute a therapeutic agent into the wall rather than the lumen of a vessel into which the stent-graft assembly is placed.

摘要翻译： 本发明提供一种支架移植组件。 组件包括至少一个支架框架和移植构件。 移植物构件邻近支架框架的内表面定位并且绕过支架框架的外表面以包围支架框架的至少一部分。 该组件可以进一步包括由移植构件封闭的治疗剂。 可以在移植物构件中形成洗脱开口，以优先地将治疗剂洗脱到壁中，而不是将放置支架移植物组件的容器的内腔排出。

公开(公告)号：US20070283969A1

公开(公告)日：2007-12-13

申请号：US11761906

申请日：2007-06-12

申请人： Dwayne Yamasaki ,  Mark Dolan

发明人： Dwayne Yamasaki ,  Mark Dolan

IPC分类号： A61F2/26 ,  A61F2/92

CPC分类号： A61F2/26 ,  A61B8/06 ,  A61F2/82

摘要： A method of diagnosing and treating a patient having erectile dysfunction by placement of a stent or paving material within a stenosed region of a pelvic vessel. The diagnosing of the patient's condition includes determining if a treatable stenosis exists within a pelvic vessel and if proper blood flow is otherwise occurring within the penile arteries.

摘要翻译： 一种通过将支架或铺路材料放置在骨盆容器的狭窄区域来诊断和治疗勃起功能障碍的患者的方法。 对患者状况的诊断包括确定在盆腔内是否存在可治疗的狭窄，以及是否在阴茎动脉内发生适当的血流。

公开(公告)号：US20070244545A1

公开(公告)日：2007-10-18

申请号：US11279776

申请日：2006-04-14

申请人： Matthew Birdsall ,  Mark Dolan ,  Darrel Untereker

发明人： Matthew Birdsall ,  Mark Dolan ,  Darrel Untereker

IPC分类号： A61F2/24

CPC分类号： A61F2/2418 ,  A61B90/39 ,  A61F2/06 ,  A61F2/2475 ,  A61F2230/0078 ,  A61F2250/006 ,  A61F2250/0098

摘要： A system and method for treating a vascular condition includes a conduit having an elongate tubular member with an outer surface and an inner surface, the inner surface defines a conduit lumen. The system further includes at least one symmetry indicator attached to the elongate tubular member and a replacement valve device. The replacement valve device includes a prosthetic valve connected to an expandable support structure. The replacement valve device is positioned within the conduit lumen adjacent the inner surface.

摘要翻译： 用于治疗血管病症的系统和方法包括具有细长管状构件的管道，其具有外表面和内表面，所述内表面限定管腔。 该系统还包括附接到细长管状构件和替换阀装置的至少一个对称指示器。 置换瓣膜装置包括连接到可扩张支撑结构的假体瓣。 替换阀装置位于与内表面相邻的管腔内。

公开(公告)号：US20060106420A1

公开(公告)日：2006-05-18

申请号：US10988462

申请日：2004-11-12

申请人： Mark Dolan ,  Asha Nayak

发明人： Mark Dolan ,  Asha Nayak

IPC分类号： A61B17/08

CPC分类号： A61B17/0057 ,  A61B17/064 ,  A61B2017/00575 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00615 ,  A61B2017/0641

摘要： A system for treating a septal defect comprises a treatment device slidably received within a catheter. The device includes a patch attached to a support. The support has a body segment and a plurality of leg segments that self-expand radially outward as the device is released from the catheter. A method for treating a septal defect comprises delivering the treatment device in the catheter proximate a septal defect. The device is slid in a distal direction to release a portion of each leg segment from the catheter, the leg segments partially expanded radially outward. The leg segments are placed in contact with tissue surrounding the septal defect. The device is slid farther until the leg segments are fully released from the catheter and fully expanded, thereby implanting a distal portion of each leg segment in tissue surrounding the septal defect and positioning the patch against the septal defect.

摘要翻译： 用于治疗间隔缺损的系统包括可滑动地容纳在导管内的治疗装置。 该装置包括附接到支撑件的贴片。 该支撑件具有主体段和多个腿段，当该装置从该导管释放时，该腿段自身径向向外扩张。 用于治疗间隔缺损的方法包括将治疗装置输送到靠近隔膜缺损的导管中。 该装置沿远端方向滑动以从导管释放每个腿段的一部分，腿段部分地径向向外扩张。 腿部段与隔膜缺损周围的组织接触。 该装置滑动得更远，直到腿部段从导管完全释放并完全膨胀，从而将每个腿段的远端部分植入围绕隔膜缺损的组织中，并将补片定位在隔膜缺损处。

公开(公告)号：US08551161B2

公开(公告)日：2013-10-08

申请号：US11739526

申请日：2007-04-24

申请人： Mark Dolan

发明人： Mark Dolan

IPC分类号： A61F2/24

CPC分类号： A61F2/2445 ,  A61F2/2442 ,  A61F2/2466 ,  A61F2210/0014 ,  A61F2220/0016 ,  A61F2230/0004 ,  A61F2230/0008

摘要： A catheter based system for treating mitral valve regurgitation includes a reshaping device having a body and a plurality of movable anchoring barbs attached to the body of the device. The reshaping device can be made from a biocompatible material having suitable shape memory properties. The devices of the current invention can be self expandable, balloon expandable, or a combination self expandable and balloon expandable. One embodiment of the invention includes a method for attaching a reshaping device to the annulus of a mitral valve, moving the body of the device from a fully expanded configuration to a resting configuration, and thereby reshaping the mitral valve annulus.

摘要翻译： 用于治疗二尖瓣反流的基于导管的系统包括具有主体的固定装置和附接到装置的主体的多个可动锚定倒钩。 整形装置可以由具有合适形状记忆特性的生物相容性材料制成。 本发明的装置可以是自膨胀的，球囊可膨胀的，或是可自膨胀和气囊扩张的组合。 本发明的一个实施例包括一种用于将整形装置附接到二尖瓣环的方法，将装置的主体从完全展开的构型移动到静止构型，从而重新形成二尖瓣环。

公开(公告)号：US20110301688A1

公开(公告)日：2011-12-08

申请号：US13210675

申请日：2011-08-16

申请人： Mark Dolan

发明人： Mark Dolan

IPC分类号： A61F2/84 ,  A61F2/24

CPC分类号： A61M25/1011 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2250/0048 ,  A61M29/02 ,  A61M2025/0039 ,  A61M2025/004

摘要： A prosthetic valve delivery system for percutaneously delivering and deploying a prosthetic valve within an existing valve is disclosed. The delivery system includes a stented prosthetic valve having a balloon-expandable stent portion with a prosthetic valve disposed therein and at least one self-expanding stent portion. The delivery system further includes a dual balloon catheter having a first balloon on which the stented prosthetic valve is disposed during delivery and a second balloon. Upon delivery within the existing valve, the self-expanding stent portion contacts the existing valve and the first balloon expands the balloon-expandable stent portion to a first diameter such that the stented prosthetic valve is in a first stage deployment configuration. The second balloon then expands the balloon-expandable stent portion to a second diameter, greater than the first diameter, such that the stented prosthetic valve is in a second stage deployment configuration being fully deployed within the existing valve.

摘要翻译： 公开了一种用于在现有阀内经皮递送和展开假体瓣膜的假体瓣膜输送系统。 输送系统包括支架假体瓣膜，其具有球囊扩张支架部分，其中设置有人工瓣膜和至少一个自扩张支架部分。 输送系统还包括具有第一气囊的双气囊导管，其中支架假体瓣膜在输送期间设置在其上并具有第二气囊。 在现有阀门内传送后，自膨胀支架部分接触现有阀门，第一气囊将球囊扩张支架部分扩张至第一直径，使得支架假体瓣膜处于第一阶段展开构型。 然后，第二气囊将球囊扩张支架部分扩大到大于第一直径的第二直径，使得支架假体瓣膜处于完全展开在现有瓣膜内的第二阶段展开构型。

公开(公告)号：US20100234940A1

公开(公告)日：2010-09-16

申请号：US12403114

申请日：2009-03-12

申请人： Mark Dolan

发明人： Mark Dolan

IPC分类号： A61F2/24 ,  A61F2/06

CPC分类号： A61M25/1011 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2250/0048 ,  A61M29/02 ,  A61M2025/0039 ,  A61M2025/004

摘要： A prosthetic valve delivery system for percutaneously delivering and deploying a prosthetic valve within an existing valve is disclosed. The delivery system includes a stented prosthetic valve having a balloon-expandable stent portion with a prosthetic valve disposed therein and at least one self-expanding stent portion. The delivery system further includes a dual balloon catheter having a first balloon on which the stented prosthetic valve is disposed during delivery and a second balloon. Upon delivery within the existing valve, the self-expanding stent portion contacts the existing valve and the first balloon expands the balloon-expandable stent portion to a first diameter such that the stented prosthetic valve is in a first stage deployment configuration. The second balloon then expands the balloon-expandable stent portion to a second diameter, greater than the first diameter, such that the stented prosthetic valve is in a second stage deployment configuration being fully deployed within the existing valve.

摘要翻译： 公开了一种用于在现有阀内经皮递送和展开假体瓣膜的假体瓣膜输送系统。 输送系统包括支架假体瓣膜，其具有球囊扩张支架部分，其中设置有人工瓣膜和至少一个自扩张支架部分。 输送系统还包括具有第一气囊的双气囊导管，其中支架假体瓣膜在输送期间设置在其上并具有第二气囊。 在现有阀门内传送后，自膨胀支架部分接触现有阀门，第一气囊将球囊扩张支架部分扩张至第一直径，使得支架假体瓣膜处于第一阶段展开构型。 然后，第二气囊将球囊扩张支架部分扩大到大于第一直径的第二直径，使得支架假体瓣膜处于完全展开在现有瓣膜内的第二阶段展开构型。

公开(公告)号：US20080189928A1

公开(公告)日：2008-08-14

申请号：US11673684

申请日：2007-02-12

申请人： Mark Dolan

发明人： Mark Dolan

IPC分类号： B23P23/00 ,  B23P13/00

CPC分类号： A61F2/91 ,  A61F2220/005 ,  A61F2250/0068 ,  Y10T29/49885 ,  Y10T29/49995 ,  Y10T29/53

摘要： A method of manufacturing a drug-carrying stent includes cutting a plurality of stent rings from a blank, stamping a plurality of dimples in at least one side of the stent rings, bending the stamped stent rings into a stent segment, and attaching the stent segments together.

摘要翻译： 制造载药支架的方法包括从坯件切割多个支架环，在支架环的至少一侧冲压多个凹坑，将冲压的支架环弯曲成支架段，并将支架段 一起。

公开(公告)号：US20080140180A1

公开(公告)日：2008-06-12

申请号：US11608081

申请日：2006-12-07

申请人： Mark Dolan ,  David Simon

发明人： Mark Dolan ,  David Simon

IPC分类号： A61F2/06 ,  A61B6/00

CPC分类号： A61F2/954 ,  A61B34/20 ,  A61B2034/105 ,  A61B2034/2051 ,  A61F2/07 ,  A61F2002/061 ,  A61F2002/067 ,  A61M2025/0166

摘要： A branch vessel in a human patient is located using in vivo tracked field sensors where in one variation the sensor positions can be located by determining the positions of the sensors relative to a plurality of magnetic field sources of known location. This approach is used, for example, in locating the opening in a renal artery and positioning the proximal end of the AAA stent-graft adjacent to the opening. According to another embodiment, field sensors in combination with signal generators are placed in vivo to locate vasculature aspects. In a further embodiment, an in vivo sensor is positioned in a deployed prosthesis to create a reference for a prosthetic member having a sensor to track to during cannulation of the deployed prosthesis with the prosthetic member.

摘要翻译： 使用体内跟踪的场传感器来定位人类患者的分支血管，其中在一个变化中，可以通过确定传感器相对于已知位置的多个磁场源的位置来定位传感器位置。 例如，该方法用于将肾动脉中的开口定位并将AAA支架移植物的近端定位成与开口相邻。 根据另一个实施例，与信号发生器组合的场传感器被放置在体内以定位脉管系统方面。 在另一实施例中，体内传感器定位在部署的假体中，以为具有传感器的假体构件创建参考，所述假体构件具有在假肢构件插入展开假体期间跟踪的传感器。