中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

19 records (took 0.03 seconds)

    Continuous, semicontinuous and batch methods for treating liquids and manufacturing certain constituents (e.g., nanoparticles) in liquids, apparatuses and nanoparticles and nanoparticle/liquid solution(s) and colloids resulting therefrom
    13.
    发明授权
    Continuous, semicontinuous and batch methods for treating liquids and manufacturing certain constituents (e.g., nanoparticles) in liquids, apparatuses and nanoparticles and nanoparticle/liquid solution(s) and colloids resulting therefrom 有权
    用于处理液体并在液体，装置和纳米颗粒中制造某些成分（例如纳米颗粒）的连续，半连续和间歇方法以及由此产生的纳米颗粒/液体溶液和胶体

    公开(公告)号：US09067263B2

    公开(公告)日：2015-06-30

    申请号：US13144221

    申请日：2010-01-13

    Applicant: David Kyle Pierce ,  Mark Gordon Mortenson ,  David Andrew Bryce ,  Adam Robert Dorfman ,  Mikhail Merzliakov ,  Arthur Maxwell Grace

    Inventor： David Kyle Pierce ,  Mark Gordon Mortenson ,  David Andrew Bryce ,  Adam Robert Dorfman ,  Mikhail Merzliakov ,  Arthur Maxwell Grace

    IPC: H05F3/00 ,  C25C1/20 ,  B01J19/08 ,  B82Y40/00 ,  B22F9/20

    CPC classification number: B22F9/20 ,  B01J19/088 ,  B01J2219/0809 ,  B01J2219/0841 ,  B01J2219/0877 ,  B01J2219/0894 ,  B22F2999/00 ,  B82Y40/00 ,  C25C1/20 ,  C25C1/22 ,  B22F2202/06 ,  B22F2202/13

    Abstract: This invention relates generally to novel methods and novel devices for the continuous manufacture of nanoparticles, microparticles and nanoparticle/liquid solution(s) (e.g., colloids). The nanoparticles (and/or micron-sized particles) comprise a variety of possible compositions, sizes and shapes. The particles (e.g., nanoparticles) are caused to be present (e.g., created and/or the liquid is predisposed to their presence (e.g., conditioned)) in a liquid (e.g., water) by, for example, preferably utilizing at least one adjustable plasma (e.g., created by at least one AC and/or DC power source), which plasma communicates with at least a portion of a surface of the liquid. At least one subsequent and/or substantially simultaneous adjustable electrochemical processing technique is also preferred. Multiple adjustable plasmas and/or adjustable electrochemical processing techniques are preferred. Processing enhancers can be utilized alone or with a plasma. Semicontinuous and batch processes can also be utilized. The continuous processes cause at least one liquid to flow into, through and out of at least one trough member, such liquid being processed, conditioned and/or effected in said trough member(s). Results include constituents formed in the liquid including ions, micron-sized particles and/or nanoparticles (e.g., metallic-based nanoparticles) of novel size, shape, composition, concentration, zeta potential and certain other novel properties present in a liquid.

    Abstract translation: 本发明一般涉及用于连续制造纳米颗粒，微粒和纳米颗粒/液体溶液（例如胶体）的新方法和新颖装置。 纳米颗粒（和/或微米尺寸的颗粒）包含各种可能的组合物，尺寸和形状。 引起颗粒（例如，纳米颗粒）存在（例如，通过例如优选利用至少一种的方式在液体（例如水）中存在（例如，产生和/或将液体倾向于其存在（例如，调节）） 可调节的等离子体（例如，由至少一个AC和/或DC电源产生），其等离子体与液体的至少一部分表面连通。 至少一个后续和/或基本上同时可调节的电化学处理技术也是优选的。 多重可调等离子体和/或可调电化学处理技术是优选的。 处理增强剂可以单独使用或与等离子体一起使用。 也可以使用半连续和间歇方法。 连续过程导致至少一种液体流入，通过和流出至少一个槽构件，这种液体在所述槽构件中被处理，调节和/或实现。 结果包括在液体中形成的成分，包括具有新颖尺寸，形状，组成，浓度，ζ电位和存在于液体中的某些其它新特性的离子，微米级颗粒和/或纳米颗粒（例如金属基纳米颗粒）。

    Method and apparatus for rapid temperature changes
    14.
    发明授权
    Method and apparatus for rapid temperature changes 有权
    快速温度变化的方法和装置

    公开(公告)号：US07626144B2

    公开(公告)日：2009-12-01

    申请号：US11535984

    申请日：2006-09-28

    Applicant: Mikhail Merzliakov

    Inventor： Mikhail Merzliakov

    IPC: H05B1/02

    CPC classification number: G01K17/006 ,  G05D23/2401

    Abstract: A method and apparatus for rapid temperature changes of thin samples is disclosed. The apparatus comprises of a thin-film resistive element embedded in a membrane, a narrow gap between the membrane and a heat sink, and a control circuit. The resistive element acts both as a heater and as a temperature sensor to reduce time constant of the control circuit. The gap between the membrane and the heat sink is filled with gas (e.g., N2 or He) acting as cooling medium with low thermal inertia. The temperature controller has a microsecond time constant, which allows adjusting rapidly the power applied to the membrane, depending on heat released/absorbed by a sample during an isotherm or during a given rate of temperature changes. The membrane has low thermal inertia and, coupled with high-speed temperature controller, allows controlled cooling and heating rates up to 100 000 K s−1 and higher. The method can be a core of any setup where controlled fast temperature-time profile of thin or small sample is desirable. The proposed control circuit can be readily applied to the variety of the existing setups with resistive heater.

    Abstract translation: 公开了一种薄样品快速温度变化的方法和装置。 该装置包括嵌入膜中的薄膜电阻元件，膜与散热器之间的窄间隙，以及控制电路。 电阻元件既作为加热器又作为温度传感器，以减少控制电路的时间常数。 膜和散热器之间的间隙填充有作为具有低热惯性的冷却介质的气体（例如，N 2或He）。 温度控制器具有微秒时间常数，这允许根据在等温线期间或在给定的温度变化期间由样品释放/吸收的热量来迅速调节施加到膜的功率。 该膜具有低热惯性，与高速温度控制器相结合，可控制冷却和加热速率高达100 000 K s-1及更高。 该方法可以是任何设备的核心，其中需要薄或小样品的受控快速温度 - 时间曲线。 所提出的控制电路可以容易地应用于具有电阻加热器的各种现有设置。

    Gold-platinum based bi-metallic nanocrystal suspensions, electrochemical manufacturing processes therefor and uses for the same
    18.
    发明授权
    Gold-platinum based bi-metallic nanocrystal suspensions, electrochemical manufacturing processes therefor and uses for the same 有权
    金 - 铂金属双金属纳米晶体悬浮液，其电化学制造工艺及其用途

    公开(公告)号：US09387225B2

    公开(公告)日：2016-07-12

    申请号：US14008931

    申请日：2012-03-30

    Applicant: Adam R. Dorfman ,  David A. Bryce ,  Maxwell A. Grace ,  D. Kyle Pierce ,  Mikhail Merzliakov ,  Mark G. Mortenson

    Inventor： Adam R. Dorfman ,  David A. Bryce ,  Maxwell A. Grace ,  D. Kyle Pierce ,  Mikhail Merzliakov ,  Mark G. Mortenson

    IPC: A61K33/24 ,  A61K9/14 ,  C22C1/04 ,  C22C5/02 ,  C22C5/04 ,  C22C30/00 ,  A61K9/10

    CPC classification number: A61K33/24 ,  A61K9/10 ,  A61K9/14 ,  A61K9/1611 ,  B82Y5/00 ,  C22C1/0466 ,  C22C5/02 ,  C22C5/04 ,  C22C30/00

    Abstract: The present invention relates to novel gold-platinum based bi-metallic nanocrystal suspensions that have nanocrystal surfaces that are substantially free from organic or other impurities or films associated with typical chemical reductants/stabilizers and/or raw materials used in nanoparticle formation processes. Specifically, the surfaces are “clean” relative to the surfaces of metal-based nanoparticles made using chemical reduction (and other) processes that require organic (or other) reductants and/or surfactants to grow (and/or suspend) metal nanoparticles from metal ions in a solution. The invention includes novel electrochemical manufacturing apparatuses and techniques for making the bi-metallic nanocrystal suspensions. The techniques do not require the use or presence of chlorine ions/atoms and/or chlorides or chlorine-based materials for the manufacturing process/final suspension. The invention further includes pharmaceutical compositions thereof and the use of the bi-metallic nanocrystals or suspensions or colloids thereof for the treatment or prevention of diseases or conditions for which metal-based therapy is already known, including, for example, for cancerous diseases or conditions.

    Abstract translation: 本发明涉及具有纳米晶体表面的新型金 - 铂基双金属纳米晶体悬浮液，其基本上不含与用于纳米颗粒形成过程中的典型化学还原剂/稳定剂和/或原料相关的有机或其它杂质或膜。 具体地说，相对于使用需要有机（或其它）还原剂和/或表面活性剂从金属生长（和/或悬浮）金属纳米粒子的化学还原（和其它）方法制备的金属基纳米颗粒的表面，表面“干净” 离子在溶液中。 本发明包括用于制备双金属纳米晶体悬浮液的新型电化学制造装置和技术。 这些技术不需要使用或存在氯离子/原子和/或氯化物或氯基材料用于制造过程/最终悬浮液。 本发明还包括其药物组合物，以及双金属纳米晶体或其悬浮液或胶体在治疗或预防金属基治疗已知的疾病或病症中的应用，包括例如癌性疾病或病症 。

    Method and Apparatus for Rapid Temperature Changes
    19.
    发明申请
    Method and Apparatus for Rapid Temperature Changes 有权
    快速温度变化的方法和装置

    公开(公告)号：US20070206654A1

    公开(公告)日：2007-09-06

    申请号：US11535984

    申请日：2006-09-28

    Applicant: Mikhail Merzliakov

    Inventor： Mikhail Merzliakov

    IPC: G01K17/00

    CPC classification number: G01K17/006 ,  G05D23/2401

    Abstract: A method and apparatus for rapid temperature changes of thin samples is disclosed. The apparatus comprises of a thin-film resistive element embedded in a membrane, a narrow gap between the membrane and a heat sink, and a control circuit. The resistive element acts both as a heater and as a temperature sensor to reduce time constant of the control circuit. The gap between the membrane and the heat sink is filled with gas (e.g., N2 or He) acting as cooling medium with low thermal inertia. The temperature controller has a microsecond time constant, which allows adjusting rapidly the power applied to the membrane, depending on heat released/absorbed by a sample during an isotherm or during a given rate of temperature changes. The membrane has low thermal inertia and, coupled with high-speed temperature controller, allows controlled cooling and heating rates up to 100,000 K s−1 and higher. The method can be a core of any setup where controlled fast temperature-time profile of thin or small sample is desirable. The proposed control circuit can be readily applied to the variety of the existing setups with resistive heater.

    Abstract translation: 公开了一种薄样品快速温度变化的方法和装置。 该装置包括嵌入膜中的薄膜电阻元件，膜与散热器之间的窄间隙，以及控制电路。 电阻元件既作为加热器又作为温度传感器，以减少控制电路的时间常数。 膜和散热器之间的间隙用作为具有低热惯性的冷却介质的气体（例如，N 2或He）填充。 温度控制器具有微秒时间常数，这允许根据在等温线期间或在给定的温度变化期间由样品释放/吸收的热量来迅速调节施加到膜的功率。 该膜具有低热惯性，并与高速温度控制器相结合，可控制冷却和加热速率高达100,000 K s -1以上。 该方法可以是任何设备的核心，其中需要薄或小样品的受控快速温度 - 时间曲线。 所提出的控制电路可以容易地应用于具有电阻加热器的各种现有设置。

Patent Agency Ranking