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    System and method for semi-projective quantitative flow imaging using accelerated arterial spin-labeled cine MRI
    11.
    发明授权
    System and method for semi-projective quantitative flow imaging using accelerated arterial spin-labeled cine MRI 有权

    公开(公告)号：US10859658B2

    公开(公告)日：2020-12-08

    申请号：US16395835

    申请日：2019-04-26

    Applicant: NORTHSHORE UNIVERSITY HEALTHSYSTEM

    Inventor： Robert R. Edelman ,  Ioannis Koktzoglou

    IPC: G01R33/563 ,  G01R33/565 ,  G01R33/561 ,  G01R33/48 ,  G01R33/56

    Abstract: A system and method for controlling a magnetic resonance imaging (MRI) system to create magnetic resonance (MR) cine angiograms of a subject. The method includes controlling the MRI system to acquire MR data from the subject by performing at least one cine acquisition pulse sequence having a plurality of acquisition RF pulse modules applied at constant intervals throughout a cardiac cycle, and at least one labeling pulse sequence including a first and a second α/2 module and a labeling RF pulse module for labeling a region of inflowing arterial flow through a vessel of interest. The method further includes reconstructing the MR data to form a series of cine frames that form a cine angiogram, subtracting at least one cine frame from other cine frames reconstructed from the MR data, and displaying the MR cine angiogram of the vessel of interest.

    SYSTEM AND METHOD FOR T1 RELAXATION ENHANCED STEADY-STATE MRI
    16.
    发明公开
    SYSTEM AND METHOD FOR T1 RELAXATION ENHANCED STEADY-STATE MRI 审中-公开

    公开(公告)号：US20240280658A1

    公开(公告)日：2024-08-22

    申请号：US18654521

    申请日：2024-05-03

    Applicant: NORTHSHORE UNIVERSITY HEALTHSYSTEM

    Inventor： Robert R. Edelman

    IPC: G01R33/56 ,  A61B5/00 ,  A61B5/055 ,  G01R33/561

    CPC classification number: G01R33/5602 ,  G01R33/5601 ,  G01R33/5608 ,  G01R33/5614 ,  A61B5/0033 ,  A61B5/055

    Abstract: A method for equilibrium phase contrast-enhanced magnetic resonance (MR) angiography using an extracellular MR contrast agent administered to a subject includes performing a balanced T1 relaxation enhanced steady-state (bT1RESS) pulse sequence to acquire MR data from a region of interest of the subject during an equilibrium phase of contrast enhancement after a first pass of the extracellular contrast agent through the region of interest. The bT1RESS pulse sequence includes a T1-weighted magnetization preparation including at least one contrast modifying (CM) radio frequency (RF) pulse, a single-shot balanced steady-state free precession (bSSFP) readout, and a time interval between the T1-weighted magnetization preparation and the acquisition of a center of k-space. The time interval is determined based on a T1 relaxation time of a contrast-enhanced blood pool and a flip angle of the at least one CM RF pulse. The method further includes generating an angiographic image of the region of interest.

    Interleaved dual-contrast unenhanced magnetic resonance angiography
    20.
    发明授权
    Interleaved dual-contrast unenhanced magnetic resonance angiography 有权

    公开(公告)号：US10568531B2

    公开(公告)日：2020-02-25

    申请号：US14927655

    申请日：2015-10-30

    Applicant: Siemens Healthcare GmbH ,  NorthShore University HealthSystem

    Inventor： Shivraman Giri ,  Robert R. Edelman

    IPC: A61B5/026 ,  G01R33/563 ,  A61B5/00 ,  A61B5/055 ,  G01R33/483

    Abstract: A method for dual-contrast unenhanced magnetic resonance angiography includes iteratively acquiring flow-dependent slices and flow-independent slices in a region. Each iteration of the acquisition process comprises identifying a flow-dependent slice location within the region and identifying a flow-independent slice location upstream from the flow-dependent slice location according to blood flow in the region. Each iteration further includes applying a first radio frequency (RF) saturation pulse to the region such that MR signals from veins in the region are substantially suppressed, and applying a second RF saturation pulse to the flow-dependent slice location such that MR signals from background muscle and arterial blood in the region are substantially suppressed. A flow independent slice is acquired at the flow-independent slice location after the second RF saturation pulse is applied and before unsaturated arterial blood has maximally flowed into the region. After acquiring the flow-independent slice, a flow-dependent slice is acquired.

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