GENE ANALYSIS AND GENERATION OF STEM CELL METHODS AND APPARATUS

    公开(公告)号:US20190105023A1

    公开(公告)日:2019-04-11

    申请号:US16211182

    申请日:2018-12-05

    IPC分类号: A61B10/02

    摘要: A surgical treatment apparatus comprises a waterjet configured to fragment tissue and provide intact cells such as stem cells with the fragmented tissue. The intact cells can be used in one or more of many ways such as for genetic or other testing, and the intact cells can be identified as stem cells. In many embodiments, the intact cells comprise stem cells. In many embodiments, a waterjet is configured to fragment tissue. The fragmented tissue can be collected with a filter having pores sized smaller than the tissue fragments. In many embodiments cavitation with a waterjet is used to fragment the tissue comprising the intact stem cells. The waterjet may comprise a waterjet immersed in a liquid comprising water so as to form a plurality of shedding pulses. The plurality of shedding pulses can be generated with a frequency sufficient to fragment the tissue. The shedding pulses can generate cavitations that fragment the tissue.

    STIFF SHEATH FOR IMAGING PROBE
    19.
    发明公开

    公开(公告)号:US20230355207A1

    公开(公告)日:2023-11-09

    申请号:US18352404

    申请日:2023-07-14

    IPC分类号: A61B8/00

    CPC分类号: A61B8/445 A61B8/4455

    摘要: An imaging probe is covered with a stiff sheath, which allows the imaging probe to move while the stiff sheath remains in a substantially fixed location for at least a portion of the surgical procedure while the probe moves within the stiff sheath. The stiff sheath may comprise sufficient stiffness to resist deformation as the imaging probe moves along an internal channel of the sheath. The sheath can be sized and shaped in many ways and may comprise one or more openings to allow fluid to move within the channel in which the probe is located.

    TISSUE TREATMENT WITH PULSATILE SHEAR WAVES

    公开(公告)号:US20220257274A1

    公开(公告)日:2022-08-18

    申请号:US17661486

    申请日:2022-04-29

    IPC分类号: A61B17/3203

    摘要: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.