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公开(公告)号:US11071601B2
公开(公告)日:2021-07-27
申请号:US16939972
申请日:2020-07-27
IPC分类号: A61B34/30 , A61B17/3203 , A61B17/32
摘要: An energy source is coupled to a probe mounted on a robotic arm, and a processor configured with instructions to release energy to resect tissue in coordination with movement of the robotic arm and probe. The tissue can be resected in accordance with a defined tissue resection volume that can be determined based on images of the patient. The probe can be moved to a plurality of positions with movement of a distal end of the robotic arm and tissue resected in accordance with the treatment plan. The distal end of the robotic arm can be configured to move to a plurality of locations and orientations to provide an appropriate position and orientation of the probe tip and energy source. The processor can be configured with instructions to pivot the probe at a location to decrease tissue movement near the pivot such as an internal location of the patient.
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公开(公告)号:US10315023B2
公开(公告)日:2019-06-11
申请号:US15976650
申请日:2018-05-10
发明人: Surag Mantri , Nikolai Aljuri , Kevin Patrick Staid , James Luis Badia , Peter Bentley , Nishey Wanchoo
摘要: Disclosed herein are improved methods and apparatuses for providing hemostasis within a cavity defined by an internal surface of a bleeding tissue space. A catheter comprising a proximal end and a distal end may be advanced into the cavity through a proximal opening of the tissue space into the cavity. A distal balloon coupled to the catheter may be positioned adjacent a distal opening of the tissue space, and expanded to seal the distal opening. A hemostatic agent may be applied from the catheter to the internal surface of the tissue space to inhibit bleeding of the tissue space. The hemostatic agent may be applied without occluding the proximal opening, the distal opening, and a path extending therebetween with the hemostatic agent.
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公开(公告)号:US20190105023A1
公开(公告)日:2019-04-11
申请号:US16211182
申请日:2018-12-05
发明人: Nikolai Aljuri , Surag Mantri
IPC分类号: A61B10/02
摘要: A surgical treatment apparatus comprises a waterjet configured to fragment tissue and provide intact cells such as stem cells with the fragmented tissue. The intact cells can be used in one or more of many ways such as for genetic or other testing, and the intact cells can be identified as stem cells. In many embodiments, the intact cells comprise stem cells. In many embodiments, a waterjet is configured to fragment tissue. The fragmented tissue can be collected with a filter having pores sized smaller than the tissue fragments. In many embodiments cavitation with a waterjet is used to fragment the tissue comprising the intact stem cells. The waterjet may comprise a waterjet immersed in a liquid comprising water so as to form a plurality of shedding pulses. The plurality of shedding pulses can be generated with a frequency sufficient to fragment the tissue. The shedding pulses can generate cavitations that fragment the tissue.
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公开(公告)号:US09848904B2
公开(公告)日:2017-12-26
申请号:US14708910
申请日:2015-05-11
发明人: Nikolai Aljuri , Surag Mantri , Luis Baez , George Surjan , Michael W. Sasnett , Jonathan Foote
IPC分类号: A61B17/3203 , A61B18/14 , A61B18/12 , A61B34/10 , A61B18/00 , A61B18/24 , A61B18/22 , A61B90/00 , A61B17/34
CPC分类号: A61B17/3203 , A61B18/12 , A61B18/148 , A61B18/1485 , A61B18/24 , A61B34/10 , A61B2017/3486 , A61B2018/00166 , A61B2018/00285 , A61B2018/00517 , A61B2018/00547 , A61B2018/00577 , A61B2018/00636 , A61B2018/00982 , A61B2018/1472 , A61B2018/2272 , A61B2018/2288 , A61B2090/378 , A61B2217/005 , A61B2217/007 , A61B2218/002 , A61B2218/007
摘要: A fluid stream is directed toward tissue to generate a plurality of shedding clouds. The fluid stream can be scanned such that the plurality of shedding clouds arrive a different overlapping locations. Each of the plurality of shedding clouds can remove a portion of the tissue. In many embodiments, an apparatus to ablate tissue comprises a source of pressurized fluid, and a nozzle coupled to the source of pressurized fluid to release a fluid stream, in which the fluid stream generates a plurality of shedding clouds.
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公开(公告)号:US10098656B2
公开(公告)日:2018-10-16
申请号:US14244452
申请日:2014-04-03
发明人: Nikolai Aljuri , Surag Mantri
摘要: Embodiments of the present invention provide improved methods and apparatus of treating the prostate. In many embodiments, at least a portion of the prostate is enucleated with a water jet, in order to decrease the invasiveness of the surgery. The access to the prostate can be provided with one or more of open surgical access, percutaneous access, or urethral access. The prostate can be enucleated such that an inner portion of the prostate comprising adenomatous tissue of the prostate is separated from a portion an outer the prostate comprising the capsule. In many embodiments, the patient is treated with energy of the water jet configured to separate the capsule from the inner tissue of the prostate and to inhibit cutting of blood vessels.
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公开(公告)号:US10016621B2
公开(公告)日:2018-07-10
申请号:US15587320
申请日:2017-05-04
发明人: Nikolai Aljuri , Surag Mantri
IPC分类号: A61N5/10 , A61M25/10 , A61B18/14 , A61B90/00 , A61B5/00 , A61B10/02 , A61B17/3203 , A61B5/06 , A61B18/12 , A61B18/22 , A61M1/00 , A61M25/00 , A61B8/12 , G01N33/574 , A61B18/16 , A61B18/00 , A61B18/04
CPC分类号: A61N5/1015 , A61B5/0071 , A61B5/0073 , A61B5/0084 , A61B5/061 , A61B8/085 , A61B8/12 , A61B10/02 , A61B10/0241 , A61B17/3203 , A61B17/32037 , A61B18/1206 , A61B18/1492 , A61B18/16 , A61B18/22 , A61B90/06 , A61B90/37 , A61B2010/0225 , A61B2017/32032 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00863 , A61B2018/046 , A61B2018/1253 , A61B2018/126 , A61B2090/067 , A61B2090/378 , A61B2090/508 , A61B2217/005 , A61B2217/007 , A61B2218/002 , A61B2218/007 , A61B2505/05 , A61B2562/0219 , A61M1/008 , A61M25/0017 , A61M25/10182 , A61M25/10185 , A61M2205/0216 , A61M2205/3334 , A61M2205/3344 , A61M2210/166 , A61N5/1007 , A61N5/1027 , A61N2005/1011 , A61N2005/1021 , A61N2005/1024 , A61N2005/1094 , G01N33/57434
摘要: A catheter treatment apparatus comprises an elongate tubular member and an expandable support. The expandable support comprises a radioactive substance to treat cancerous tissue and is configured to expand from a narrow profile for insertion to a wide profile to engage and treat tissue remaining after resection. The expandable support can be sized to fit within a volume of removed tissue to place the radioactive substance in proximity to the capsule and remaining tissue, to spare the capsule and proximate nerves and vessels to treat tissue in proximity to the capsule. The elongate tubular member may comprise a channel such as a lumen to pass a bodily fluid such as urine when the expandable support engages the tissue to treat the patient for a plurality of days. The treatment apparatus can be used to resect and diagnose tissue concurrently. Based on the diagnosis, targeted segmental treatment may be given.
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公开(公告)号:US20170232271A1
公开(公告)日:2017-08-17
申请号:US15388449
申请日:2016-12-22
发明人: Nikolai Aljuri , Rodney Perkins , Surag Mantri
CPC分类号: A61N5/1015 , A61B5/0071 , A61B5/0073 , A61B5/0084 , A61B5/061 , A61B8/085 , A61B8/12 , A61B10/02 , A61B10/0241 , A61B17/3203 , A61B17/32037 , A61B18/1206 , A61B18/1492 , A61B18/16 , A61B18/22 , A61B90/06 , A61B90/37 , A61B2010/0225 , A61B2017/32032 , A61B2018/0022 , A61B2018/00547 , A61B2018/00577 , A61B2018/00595 , A61B2018/00863 , A61B2018/046 , A61B2018/1253 , A61B2018/126 , A61B2090/067 , A61B2090/378 , A61B2090/508 , A61B2217/005 , A61B2217/007 , A61B2218/002 , A61B2218/007 , A61B2505/05 , A61B2562/0219 , A61M1/008 , A61M25/0017 , A61M25/10182 , A61M25/10185 , A61M2205/0216 , A61M2205/3334 , A61M2205/3344 , A61M2210/166 , A61N5/1007 , A61N5/1027 , A61N2005/1011 , A61N2005/1021 , A61N2005/1024 , A61N2005/1094 , G01N33/57434
摘要: A catheter treatment apparatus comprises an elongate tubular member and an expandable support. The expandable support comprises a radioactive substance to treat cancerous tissue and is configured to expand from a narrow profile for insertion to a wide profile to engage and treat tissue remaining after resection. The expandable support can be sized to fit within a volume of removed tissue to place the radioactive substance in proximity to the capsule and remaining tissue, to spare the capsule and proximate nerves and vessels to treat tissue in proximity to the capsule. The elongate tubular member may comprise a channel such as a lumen to pass a bodily fluid such as urine when the expandable support engages the tissue to treat the patient for a plurality of days. The treatment apparatus can be used to resect and diagnose tissue concurrently. Based on the diagnosis, targeted segmental treatment may be given.
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公开(公告)号:US09510853B2
公开(公告)日:2016-12-06
申请号:US14816747
申请日:2015-08-03
发明人: Nikolai Aljuri , Surag Mantri , Luis Baez , George Surjan , Michael W. Sasnett , Jonathan Foote
CPC分类号: A61B17/3203 , A61B18/12 , A61B18/148 , A61B18/1485 , A61B18/24 , A61B34/10 , A61B2017/3486 , A61B2018/00166 , A61B2018/00285 , A61B2018/00517 , A61B2018/00547 , A61B2018/00577 , A61B2018/00636 , A61B2018/00982 , A61B2018/1472 , A61B2018/2272 , A61B2018/2288 , A61B2090/378 , A61B2217/005 , A61B2217/007 , A61B2218/002 , A61B2218/007
摘要: A fluid stream is directed toward tissue to generate a plurality of shedding clouds. The fluid stream can be scanned such that the plurality of shedding clouds arrive a different overlapping locations. Each of the plurality of shedding clouds can remove a portion of the tissue. In many embodiments, an apparatus to ablate tissue comprises a source of pressurized fluid, and a nozzle coupled to the source of pressurized fluid to release a fluid stream, in which the fluid stream generates a plurality of shedding clouds.
摘要翻译: 流体流被引向组织以产生多个脱落云。 可以扫描流体流,使得多个脱落的云到达不同的重叠位置。 多个脱落云中的每一个可以去除组织的一部分。 在许多实施例中,用于烧蚀组织的装置包括加压流体源,以及连接到加压流体源以释放流体流的喷嘴,其中流体流产生多个脱落云。
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公开(公告)号:US11337719B2
公开(公告)日:2022-05-24
申请号:US16121489
申请日:2018-09-04
发明人: Nikolai Aljuri , Surag Mantri
摘要: Embodiments of the present invention provide improved methods and apparatus of treating the prostate. In many embodiments, at least a portion of the prostate is enucleated with a water jet, in order to decrease the invasiveness of the surgery. The access to the prostate can be provided with one or more of open surgical access, percutaneous access, or urethral access. The prostate can be enucleated such that an inner portion of the prostate comprising adenomatous tissue of the prostate is separated from a portion an outer the prostate comprising the capsule. In many embodiments, the patient is treated with energy of the water jet configured to separate the capsule from the inner tissue of the prostate and to inhibit cutting of blood vessels.
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10.
公开(公告)号:US11278293B2
公开(公告)日:2022-03-22
申请号:US16376806
申请日:2019-04-05
发明人: Surag Mantri , Nikolai Aljuri , Kevin Patrick Staid , James Luis Badia , Peter Bentley , Nishey Wanchoo
IPC分类号: A61B17/00 , A61B17/12 , A61B18/00 , A61M25/10 , A61M39/06 , A61N5/10 , A61N5/00 , A61B90/00 , A61M25/01 , A61F13/00 , A61F13/02 , A61B18/14
摘要: Disclosed herein are improved methods and apparatuses for providing hemostasis within a cavity defined by an internal surface of a bleeding tissue space. A catheter comprising a proximal end and a distal end may be advanced into the cavity through a proximal opening of the tissue space into the cavity. A distal balloon coupled to the catheter may be positioned adjacent a distal opening of the tissue space, and expanded to seal the distal opening. A hemostatic agent may be applied from the catheter to the internal surface of the tissue space to inhibit bleeding of the tissue space. The hemostatic agent may be applied without occluding the proximal opening, the distal opening, and a path extending therebetween with the hemostatic agent.
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