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    Optical resin composition comprising thiol-ene prepolymer
    14.
    发明授权
    Optical resin composition comprising thiol-ene prepolymer 失效
    包含硫醇 - 烯预聚物的光学树脂组合物

    公开(公告)号：US06669873B1

    公开(公告)日：2003-12-30

    申请号：US09524619

    申请日：2000-03-14

    Applicant: Robert A. Smith ,  Robert D. Herold ,  Michael O. Okoroafor

    Inventor： Robert A. Smith ,  Robert D. Herold ,  Michael O. Okoroafor

    IPC: G02B523

    CPC classification number: G02B1/04 ,  C08G75/045 ,  C08G75/12 ,  C08L33/14 ,  C08L81/02

    Abstract: Described is a polymerizable organic composition comprising: (a) a radically polymerizable gel-free prepolymer of (i) at least one first polymerizable monomer having at least two radically polymerizable ethylenically unsaturated groups, e.g., divinyl benzene, and (ii) at least one first polythiol monomer having at least two thiol groups, e.g., thioglycerol bis(mercaptoacetate); and (b) at least one second polymerizable monomer having at least two radically polymerizable ethylenically unsaturated groups, e.g., divinyl benzene and/or methacrylic anhydride, the first and second radically polymerizable monomers each being substantially free of norbornene groups. The molar equivalent ratio of ethylenically unsaturated groups of (a)(i) to the thiol groups of (a)(ii) is no greater than 1:1. The described polymerizable composition has reduced shrinkage, and a polymerizate prepared therefrom has a refractive index of at least 1.57 and an Abbe number of at least 33.

    Abstract translation: 描述了一种可聚合的有机组合物，其包含：（a）可自由基聚合的无凝胶预聚物，其包含（i）至少一种具有至少两个可自由基聚合的烯属不饱和基团的第一可聚合单体，例如二乙烯基苯，和（ii）至少一种 具有至少两个硫醇基的第一多硫醇单体，例如硫代甘油双（巯基乙酸酯）; 和（b）至少一种具有至少两个可自由基聚合的烯键式不饱和基团的第二可聚合单体，例如二乙烯基苯和/或甲基丙烯酸酐，第一和第二可自由基聚合单体各自基本上不含降冰片烯基团。 （a）（i）的烯属不饱和基团与（a）（ii）的硫醇基团的摩尔当量比不大于1:1。 所述可聚合组合物的收缩率降低，由其制备的聚合物的折射率至少为1.57，阿贝数为33。

    Pulse oximetry sensor adapter
    15.
    发明授权
    Pulse oximetry sensor adapter 有权

    公开(公告)号：US06597933B2

    公开(公告)日：2003-07-22

    申请号：US09982453

    申请日：2001-10-17

    Applicant: Massi E. Kiani ,  Robert A. Smith ,  David R. Tobler

    Inventor： Massi E. Kiani ,  Robert A. Smith ,  David R. Tobler

    IPC: A61B500

    CPC classification number: A61B5/14551 ,  A61B5/14552 ,  A61B2562/222 ,  G06F19/00 ,  Y10S439/909

    Abstract: An adapter allows the interconnection of a sensor originating from one manufacturer to be coupled with conventionally incompatible monitors originating from other manufacturers to form a properly functioning pulse oximetry system. The adapter matches a sensor driver in a monitor to the current requirements and light source configuration of a sensor. The adapter also matches a sensor's light detector signal level to the dynamic range requirements of a monitor preamplifier. Further, the adapter provides compatible sensor calibration, sensor type and security information to a monitor. The adapter may have a self-contained power source or it may derive power from the monitor, allowing both passive and active adapter components. The adapter is particular suited as an adapter cable, replacing a conventional patient cable or sensor cable as the interconnection between a sensor to a monitor in a pulse oximetry system.

    Photochromic organic resin composition
    16.
    发明授权
    Photochromic organic resin composition 有权
    光致变色有机树脂组合物

    公开(公告)号：US06531076B2

    公开(公告)日：2003-03-11

    申请号：US09766554

    申请日：2001-01-19

    Applicant: John C. Crano ,  Carol L. Knox ,  Michael O. Okoroafor ,  Robert A. Smith ,  Rifat Tabakovic

    Inventor： John C. Crano ,  Carol L. Knox ,  Michael O. Okoroafor ,  Robert A. Smith ,  Rifat Tabakovic

    IPC: G02B523

    CPC classification number: G03C1/733 ,  C08G18/12 ,  C08G18/6611 ,  C08G18/758 ,  C08G2120/00 ,  C08K5/0091 ,  C08K5/1545 ,  C08K5/34 ,  C08K5/35 ,  G02B5/23 ,  Y10T428/31551 ,  Y10T428/31554 ,  Y10T428/31562 ,  Y10T428/31573 ,  C08G18/3225

    Abstract: Described are photochromic organic resin compositions and the impact resistant polymerizates and coating compositions made therefrom. The organic resin composition comprises the reaction product of at least one polyol having greater than 1.0 hydroxyl groups; at least one polyisocyanate having greater than 1.0 isocyanato groups; and at least one polyamine curing agent having greater than 1.0 amino groups. The polymerizates are made photochromic either by the addition of organic photochromic compounds to the reactants used to form the polymerizate or by methods that imbibe or transfer the photochromic compounds into the polymerizate. Optically clear photochromic and impact resistant articles such as ophthalmic lenses and articles having photochromic coatings prepared from the photochromic organic resin compositions are also described.

    Abstract translation: 描述了光致变色有机树脂组合物和由其制备的耐冲击聚合物和涂料组合物。 有机树脂组合物包含至少一种具有大于1.0个羟基的多元醇的反应产物; 至少一种具有大于1.0个异氰酸酯基的多异氰酸酯; 和至少一种具有大于1.0个氨基的多胺固化剂。 通过向用于形成聚合物的反应物中加入有机光致变色化合物或通过将光致变色化合物吸收或转移到聚合物中的方法，将聚合物制成光致变色。 还描述了由光致变色有机树脂组合物制备的光学透明的光致变色和耐冲击制品例如眼镜片和具有光致变色涂层的制品。

    Keratin-based hydrogel for biomedical applications and method of production
    17.
    发明授权
    Keratin-based hydrogel for biomedical applications and method of production 有权
    用于生物医学应用的角蛋白基水凝胶和生产方法

    公开(公告)号：US06379690B2

    公开(公告)日：2002-04-30

    申请号：US09736957

    申请日：2000-12-12

    Applicant: Cheryl R. Blanchard ,  Scott F. Timmons ,  Robert A. Smith

    Inventor： Cheryl R. Blanchard ,  Scott F. Timmons ,  Robert A. Smith

    IPC: A61F1300

    CPC classification number: C08H1/06 ,  A61K8/042 ,  A61K8/65 ,  A61K38/1709 ,  A61K38/39 ,  A61L26/0047 ,  A61L26/008 ,  A61L27/227 ,  A61L27/34 ,  A61L27/52 ,  A61L27/60 ,  A61L31/047 ,  A61L31/10 ,  A61Q19/00 ,  C07K14/4741 ,  Y10S514/944 ,  Y10S530/842 ,  C08L89/04 ,  C08L89/00

    Abstract: A keratin hydrogel which can be used as a wound dressing and cell scaffolding. The keratin hydrogel is formed from clean, washed hair by partially oxidizing a significant percentage of disulfide linkages to form cysteic acid groups, while some disulfide linkages remain intact. The partially oxidized hair is treated with a reducing agent, thereby reducing most of the remaining disulfide linkages to cysteine-thioglycollate disulfide and cysteine groups. A soluble fraction of hair is collected and oxidized, such that the reduced sulfur groups are allowed to reform disulfide linkages, thereby binding the keratin together. The cysteic acid groups remain, providing hydrophilic sites within the hydrogel. A higher degree of partial oxidation results in a greater abundance of hydrophilic cysteic acid groups in the hydrogel.

    Abstract translation: 可用作伤口敷料和细胞脚手架的角蛋白水凝胶。 通过部分氧化显着百分比的二硫键以形成半胱氨酸基团，由干净的洗涤毛发形成角蛋白水凝胶，而一些二硫键保持完整。 用还原剂处理部分氧化的毛发，从而将大部分剩余的二硫键连接到半胱氨酸 - 巯基乙酸酯二硫化物和半胱氨酸基团。 收集毛发的可溶性部分并进行氧化，使得还原的硫基团能够改性二硫键，从而将角蛋白结合在一起。 残留的半胱氨酸基团，在水凝胶内提供亲水部位。 较高程度的部分氧化导致水凝胶中亲水性半胱氨酸基团的丰度较大。

    Pulse oximetry sensor adapter
    18.
    发明授权
    Pulse oximetry sensor adapter 有权
    脉搏血氧饱和度传感器适配器

    公开(公告)号：US06349228B1

    公开(公告)日：2002-02-19

    申请号：US09404060

    申请日：1999-09-23

    Applicant: Massi E. Kiani ,  Robert A. Smith ,  David R. Tobler

    Inventor： Massi E. Kiani ,  Robert A. Smith ,  David R. Tobler

    IPC: A61B500

    CPC classification number: A61B5/14551 ,  A61B5/14552 ,  A61B2562/222 ,  G06F19/00 ,  Y10S439/909

    Abstract: An adapter allows the interconnection of a sensor originating from one manufacturer to be coupled with conventionally incompatible monitors originating from other manufacturers to form a properly functioning pulse oximetry system. The adapter matches a sensor driver in a monitor to the current requirements and light source configuration of a sensor. The adapter also matches a sensor's light detector signal level to the dynamic range requirements of a monitor preamplifier. Further, the adapter provides compatible sensor calibration, sensor type and security information to a monitor. The adapter may have a self-contained power source or it may derive power from the monitor, allowing both passive and active adapter components. The adapter is particular suited as an adapter cable, replacing a conventional patient cable or sensor cable as the interconnection between a sensor to a monitor in a pulse oximetry system.

    Abstract translation: 适配器允许来自一个制造商的传感器的互连与来自其他制造商的常规不兼容的监视器耦合以形成正常工作的脉搏血氧饱和度系统。 适配器将监视器中的传感器驱动器与传感器的当前要求和光源配置相匹配。 适配器还将传感器的光检测器信号电平与监视器前置放大器的动态范围要求相匹配。 此外，适配器向监视器提供兼容的传感器校准，传感器类型和安全信息。 适配器可以具有独立的电源，或者可以从监视器获得电力，从而允许被动和主动适配器组件。 适配器特别适合作为适配器电缆，替代传统的患者电缆或传感器电缆作为脉搏血氧仪系统中传感器与监护仪之间的互连。

    Methods for controlling insect pests with compositions containing Bacillus thuringiensis strains
    19.
    发明授权
    Methods for controlling insect pests with compositions containing Bacillus thuringiensis strains 失效
    用含有苏云金芽孢杆菌菌株的组合物控制害虫的方法

    公开(公告)号：US06258356B1

    公开(公告)日：2001-07-10

    申请号：US08770452

    申请日：1996-12-20

    Applicant: David R. Wilcox ,  Robert A. Smith ,  Terry A. Benson

    Inventor： David R. Wilcox ,  Robert A. Smith ,  Terry A. Benson

    IPC: A01N6300

    CPC classification number: C07K14/325 ,  A01N63/00 ,  Y10S435/832

    Abstract: Novel bacterial isolates of B. thuringiensis are disclosed which have enhanced toxicity with respect to previously resistant or insufficiently susceptible insect species, including, but not limited to, Plutella xylostella, Spodoptera frugiperda and Spodoptera exigua, as well as certain secondary pests such as Trichoplusia ni. Such isolates may be characterized by their possession of a particular subset of the genes coding for the various B. thuringiensis &dgr;-endotoxin proteins and by a characteristic plasmid profile, or array, known to be associated therewith. Also disclosed are a method for the efficient identification of such bacterial isolates utilizing generalized or, alternatively, gene-specific DNA probes; cloned or synthesized nucleotide sequences which are useful in the preparation of those probes; compositions containing an insecticidally effective amount of a bacterial isolate of the invention in combination with an acceptable carrier; and a method for the use thereof in the control or eradication of insect pests.

    Abstract translation: 公开了苏云金芽孢杆菌的新型细菌分离物，其对先前抗性或不充分易感的昆虫物种具有增强的毒性，包括但不限于小菜蛾，草地贪夜蛾和草地夜蛾以及某些次生害虫如毛滴虫 。 这样的分离物的特征可以在于它们拥有编码各种苏云金芽孢杆菌δ-内毒素蛋白质的基因的特定子集，以及已知与之相关的特征性质粒谱或阵列。还公开了一种有效的方法 使用广泛的或者基因特异性DNA探针鉴定这样的细菌分离物; 克隆或合成的可用于制备这些探针的核苷酸序列; 含有杀虫有效量的本发明细菌分离物与可接受载体组合的组合物; 以及用于控制或根除害虫的方法。

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