公开(公告)号：US20100075360A1

公开(公告)日：2010-03-25

申请号：US12234804

申请日：2008-09-22

Applicant: Muhammed Majeed ,  Susmitha Anand ,  Geetha Kanhangad Gangadharan ,  Subbalakshmi Prakash

Inventor： Muhammed Majeed ,  Susmitha Anand ,  Geetha Kanhangad Gangadharan ,  Subbalakshmi Prakash

IPC: C12Q1/02

CPC classification number: G01N33/5008

Abstract: Disclosed is a simple method of determining SPF based on the staining pattern of viable cells like mouse fibroblasts and human keratinocytes after exposure to ultraviolet radiations. The method provides results comparable to the standard methods of SPF measurement using human subjects.

Abstract translation: 公开了一种基于在暴露于紫外线辐射后的活细胞如小鼠成纤维细胞和人角质形成细胞的染色模式来确定SPF的简单方法。 该方法提供与使用人类受试者的SPF测量的标准方法相当的结果。

公开(公告)号：US20070196507A1

公开(公告)日：2007-08-23

申请号：US11696187

申请日：2007-04-04

Applicant: Muhammed Majeed ,  Geetha Kanhangad Gangadharan ,  Subbalakshmi Prakash

Inventor： Muhammed Majeed ,  Geetha Kanhangad Gangadharan ,  Subbalakshmi Prakash

IPC: A61K35/64

CPC classification number: C12P7/04 ,  Y02P20/544

Abstract: The present invention discloses the cosmetic applications of alkylalkanols collectively referred to as policosanol, for control of sebum secretion, as anti-acne component and as emollient.

Abstract translation: 本发明公开了将烷基链烷醇统称为二十烷醇，用于控制皮脂分泌，作为抗痤疮成分和润肤剂的化妆品应用。

公开(公告)号：US07217546B1

公开(公告)日：2007-05-15

申请号：US10604203

申请日：2003-07-01

Applicant: Muhammed Majeed ,  KalkunteSeshadri Satyan ,  KanhangadGangadharan Geetha ,  Tirumale Sharmila ,  Subbalakshmi Prakash

Inventor： Muhammed Majeed ,  KalkunteSeshadri Satyan ,  KanhangadGangadharan Geetha ,  Tirumale Sharmila ,  Subbalakshmi Prakash

IPC: C12P7/04 ,  C12P7/02

CPC classification number: C12P7/04 ,  Y02P20/544

Abstract: The present invention discloses an economically viable process for producing large quantity of higher fatty alcohol of chain length C24–C36 from natural waxes. The said alkanols have enriched percentage of 70–95% of C28 fatty alcohol (Octacosanol) along with less percentage of lower chain length fatty alcohols. The invention discloses the use of supercritical carbon dioxide extraction along with immobilized enzyme for saponification. The present invention also discloses the cosmetic applications of alkyalkanols collectively referred to as policosanol, for control of sebum secretion and as anti-acne component effectively used in cosmetic formulations.

Abstract translation: 本发明公开了一种经济上可行的方法，用于从天然蜡生产大量链长C 26 -C 36 -C 36高级脂肪醇。 所述链烷醇具有70-95％的C 28脂肪醇（二十八烷醇）的富集百分比以及较低链长链脂肪醇的百分比。 本发明公开了超临界二氧化碳萃取与固定化酶的皂化作用。 本发明还公开了用于控制皮脂分泌的烷基链烷醇统称为二十烷醇的化妆品应用，以及有效用于化妆品制剂中的抗痤疮成分。

公开(公告)号：US20060198906A1

公开(公告)日：2006-09-07

申请号：US11308111

申请日：2006-03-07

Applicant: Muhammed Majeed ,  Subbalakshmi Prakash

Inventor： Muhammed Majeed ,  Subbalakshmi Prakash

IPC: A61K36/906 ,  A61K36/67 ,  A61K36/889 ,  A61K36/324 ,  A61K31/198 ,  A61K31/195

CPC classification number: A61K36/38 ,  A61K31/195 ,  A61K31/198 ,  A61K33/04 ,  A61K36/328 ,  A61K36/67 ,  A61K36/889 ,  A61K36/9066 ,  A61K45/06 ,  A61K2300/00

Abstract: The invention provides a method for increasing serum high density lipoprotein (HDL) cholesterol levels, and lowering serum levels of Lipoprotein (a) and C-reactive protein, as well as a suitable composition comprising a) a vegetable protein, b) a natural antioxidant compound, c) a natural anti-inflammatory compound, d) a bioavailable source of selenium, e) a natural blend of long chain aliphatic alcohols termed policosanol; and f) a natural bioavailability enhancer.

Abstract translation: 本发明提供了一种增加血清高密度脂蛋白（HDL）胆固醇水平和降低脂蛋白（a）和C-反应蛋白的血清水平的方法，以及合适的组合物，其包含a）植物蛋白，b）天然抗氧化剂 化合物，c）天然抗炎化合物，d）硒的生物可利用来源，e）被称为二十烷醇的长链脂族醇的天然共混物; 和f）天然生物利用度增强剂。

公开(公告)号：US20060122261A1

公开(公告)日：2006-06-08

申请号：US10707087

申请日：2003-11-20

Applicant: Muhammed Majeed ,  Rajinder Kumar Bammi ,  Natarajan Sankaran ,  Rajendran Ramanujam ,  Satyan Kalkunte Seshadri ,  Subbalakshmi Prakash

Inventor： Muhammed Majeed ,  Rajinder Kumar Bammi ,  Natarajan Sankaran ,  Rajendran Ramanujam ,  Satyan Kalkunte Seshadri ,  Subbalakshmi Prakash

IPC: A61K31/353

CPC classification number: A61K31/353

Abstract: The invention describes methods of preparation of isoforskolin extract, deacetylforskolin extract and related compounds from a natural source. Compositions and human and veterinary applications of such extracts in weight management through promoting lean body mass and in topical preparations for cellulite control, are also described. The compositions of the invention could be administered in a variety of dosage forms, including but not limited to ready-to-serve beverages, dry mixes for food products and beverages, oral preparations, injectables, emulsions, liniments or oils, to humans or animals.

Abstract translation: 本发明描述了异佛尔酮蛋白提取物，脱乙酰福斯克林提取物以及天然来源的相关化合物的制备方法。 还描述了通过促进瘦体重和用于脂肪团控制的局部制剂中的这些提取物在体重管理中的组合物和人和兽医学应用。 本发明的组合物可以以各种剂型施用，包括但不限于即食服务饮料，食品和饮料的干混物，口服制剂，注射剂，乳剂，搽剂或油，用于人或动物 。

公开(公告)号：US06982273B1

公开(公告)日：2006-01-03

申请号：US10707716

申请日：2004-01-06

Applicant: Muhammed Majeed ,  Nagarajan Ananthanarayanan ,  Nagabhushanam Kalyanam ,  Ramanujam Rajendran ,  Seena George ,  Subbalakshmi Prakash

Inventor： Muhammed Majeed ,  Nagarajan Ananthanarayanan ,  Nagabhushanam Kalyanam ,  Ramanujam Rajendran ,  Seena George ,  Subbalakshmi Prakash

IPC: A61K31/445

CPC classification number: C07C391/00 ,  C07B2200/07

Abstract: The invention discloses compositions containing Se-methyl-L-selenocysteine with enhanced bioavailability and superior antioxidant and immunomodulatory activity. These compositions can be used for nutritional supplementation in humans and animals.

Abstract translation: 本发明公开了含有具有增强的生物利用度和优异的抗氧化和免疫调节活性的Se-甲基-L-硒代半胱氨酸的组合物。 这些组合物可用于人和动物中的营养补充。

公开(公告)号：US20050051483A1

公开(公告)日：2005-03-10

申请号：US10605086

申请日：2003-09-08

Applicant: Muhammed Majeed ,  Arvind Kumar ,  Kalyanam Nagabhushanam ,  Subbalakshmi Prakash

Inventor： Muhammed Majeed ,  Arvind Kumar ,  Kalyanam Nagabhushanam ,  Subbalakshmi Prakash

IPC: A23L1/30 ,  A61K9/00 ,  A61K31/352 ,  A61K45/06 ,  A61K47/40 ,  C07D311/92 ,  B01D11/00

CPC classification number: A61K9/0014 ,  A23L33/105 ,  A23V2002/00 ,  A61K9/0019 ,  A61K31/352 ,  A61K45/06 ,  A61K47/40 ,  C07D311/92 ,  Y10S514/909 ,  Y10S514/913 ,  A61K2300/00 ,  A23V2250/21 ,  A23V2250/5112

Abstract: Aqueous solutions of diterpenes such as Forskolin, its congeners, analogs and derivatives, up to approximately 6% concentration, are prepared using suitably substituted cyclodextrin as a solubilizing agents. In the absence of cyclodextrin, some diterpenes such as Forskolin are soluble in water only to concentrations of about 0.001%. Such aqueous solutions find applications in topical and systemic use, as pharmaceutical, cosmeceutical, nutraceutical preparations containing diterpenes such as Forskolin and congeners.

Abstract translation: 使用适当取代的环糊精作为增溶剂制备高达约6％浓度的二萜类如福斯克林，其同系物，类似物和衍生物的水溶液。 在没有环糊精的情况下，一些二萜如福斯克林可溶于水中，仅浓度约为0.001％。 这种水溶液可用于局部和全身用途，作为含有二萜类例如福斯柯林（Forskolin）和同系物的同类物质的药物，药妆，营养制剂。

公开(公告)号：US06607712B2

公开(公告)日：2003-08-19

申请号：US10078262

申请日：2002-02-20

Applicant: Muhammed Majeed ,  Subbalakshmi Prakash

Inventor： Muhammed Majeed ,  Subbalakshmi Prakash

IPC: A61K3578

CPC classification number: A61Q17/005 ,  A61K8/31 ,  A61K8/35 ,  A61K8/37 ,  A61K8/922 ,  A61K36/53 ,  A61Q11/00 ,  A61Q19/00 ,  C11B9/022 ,  Y02A50/473 ,  A61K2300/00

Abstract: An essential oil composition from Coleus forskohlii is used in compositions and methods for the treatment of skin infections and in the prevention and treatment of dental caries.

Abstract translation: 用于治疗皮肤感染和预防和治疗龋齿的组合物和方法中使用来自Coleus forskohlii的精油组合物。

公开(公告)号：US08394852B2

公开(公告)日：2013-03-12

申请号：US12872675

申请日：2010-08-31

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Samuel Manoharan Thomas ,  Subbalakshmi Prakash

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Samuel Manoharan Thomas ,  Subbalakshmi Prakash

IPC: A61K31/34

CPC classification number: C07D307/58 ,  A23L31/00 ,  A23L33/10 ,  A61K31/341

Abstract: Optimal compositions of derivatives of 5-methyl-3(2H)-furanone compounds and phenylpropanoid polyketides related to inotilone, that exert biological response modification in health and disease, and their method of preparation, are disclosed. Methods of treating degenerative conditions stemming from over-expression of inducible nitric oxide synthase (iNOS) using these compositions are also disclosed.

Abstract translation: 本发明公开了5-甲基-3（2H） - 呋喃酮化合物和苯丙素类聚酮化合物与艾吐子酮有关的衍生物的最佳组合物，其在健康和疾病中发挥生物反应修饰及其制备方法。 还公开了使用这些组合物治疗由诱导型一氧化氮合酶（iNOS）过表达引起的退行性病症的方法。

公开(公告)号：US07582314B2

公开(公告)日：2009-09-01

申请号：US10710778

申请日：2004-08-02

Applicant: Muhammed Majeed ,  Subbalakshmi Prakash

Inventor： Muhammed Majeed ,  Subbalakshmi Prakash

IPC: A61K36/324 ,  A61K36/00

CPC classification number: A61K31/704 ,  A61K31/198 ,  A61K36/324 ,  A61K2300/00

Abstract: The invention describes compositions and methods for the management of hyperproliferative skin conditions such as psoriasis. The preferential composition contains a natural leukotriene inhibitor selected from Boswellia serrata gum resin, its extractives, isolates or derivatives in combination with a bioavailable organic selenium nutritional supplement. These compositions are administered orally and topically to the individual human or animal in need of treatment at optimal levels to manifest the desired benefits, with no untoward side effects

Abstract translation: 本发明描述了用于治疗过度增生性皮肤病症如牛皮癣的组合物和方法。 优选组合物含有天然白三烯抑制剂，其选自芥子油树胶，其提取物，分离物或衍生物与生物可利用的有机硒营养补充剂组合。 将这些组合物口服和局部给予需要以最佳水平治疗的个体人或动物，以表现出期望的益处，而没有不利的副作用