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17 条记录 (耗时 0.021 秒)

    COLD AND/OR HEAT ACCUMULATOR
    11.
    发明申请
    COLD AND/OR HEAT ACCUMULATOR 有权
    冷热蓄热器

    公开(公告)号：US20100018667A1

    公开(公告)日：2010-01-28

    申请号：US12302222

    申请日：2006-05-29

    申请人： Noureddine Khelifa ,  Wolfgang Krämer ,  Steffen Korfmann ,  Thomas Peters

    发明人： Noureddine Khelifa ,  Wolfgang Krämer ,  Steffen Korfmann ,  Thomas Peters

    IPC分类号： F28D17/04 ,  F28D20/02

    CPC分类号： F28F9/002 ,  F28D1/0478 ,  F28D20/023 ,  F28D2020/0013 ,  F28D2020/0021 ,  F28F21/02 ,  F28F2265/30 ,  Y02E60/145

    摘要： The invention relates to a cold and/or heat accumulator comprising a first heat exchanger and preferably a second heat exchanger. The first heat exchanger may, in particular, be provided to be perfused by a refrigerant while the second heat exchanger is preferably perfused by brine. The first heat exchanger and preferably also the second heat exchanger are engaged in a heat-exchanging relationship with carrier elements charged with a cold or heat storage medium and may, in particular, be formed by graphite strips. The cooling energy and/or heat accumulator according to the invention exhibits a good heat conduction, short charging times, a high cooling or heating performance, low pressure losses as well as a good cooling agent distribution. Further its integration options are manifold due to the selected fixation means.

    摘要翻译： 本发明涉及一种包含第一热交换器和优选第二热交换器的冷和/或蓄热器。 特别地，第一热交换器可以被设置成由制冷剂灌注，而第二热交换器优选地被盐水灌注。 第一热交换器，并且优选地还有第二热交换器与加载有冷或热存储介质的载体元件以热交换关系接合，并且可以特别地由石墨条形成。 根据本发明的冷却能量和/或蓄热器表现出良好的导热性，较短的充电时间，高的冷却或加热性能，低的压力损失以及良好的冷却剂分布。 此外，由于所选择的固定装置，其集成选项是多方面的。

    Magnetic wrench attachment
    14.
    发明授权
    Magnetic wrench attachment 失效
    磁力扳手附件

    公开(公告)号：US07162938B1

    公开(公告)日：2007-01-16

    申请号：US11131855

    申请日：2005-05-18

    申请人： Thomas Peters

    发明人： Thomas Peters

    IPC分类号： B25B13/02 ,  B25B13/58

    CPC分类号： B25B13/58 ,  B25B23/12

    摘要： The present invention is an attachment that fits onto the head of a wrench to magnetically hold a nut. The attachment has a magnetized surface and a side surface to friction fit onto a wrench. Fit is further improved by magnetizing the side surface. By holding the nut, the attachment allows for operation of a wrench in restrictive spaces where manual holding of the nut would be impossible or impracticable. Making side surfaces of the attachment out of plastic allows the attachment to adapt to different sizes of wrench heads. A hole in the attachment allows a bolt to pass through the attachment as it passes through the nut.

    摘要翻译： 本发明是一种安装在扳手的头部上以磁性地保持螺母的附件。 附件具有磁化表面和摩擦配合在扳手上的侧表面。 通过磁化侧面进一步改善装配。 通过握住螺母，附件允许在限制空间中操作扳手，其中手动保持螺母是不可能的或不可行的。 将附件的侧表面从塑料制成允许附件适应不同尺寸的扳手头。 附件中的孔允许螺栓在穿过螺母时穿过附件。

    Spinster-like protein genes, expression products, non-human animal model: uses in human metabolic disorders
    15.
    发明申请
    Spinster-like protein genes, expression products, non-human animal model: uses in human metabolic disorders 审中-公开
    Spinster样蛋白基因，表达产物，非人动物模型：用于人类代谢紊乱

    公开(公告)号：US20050020527A1

    公开(公告)日：2005-01-27

    申请号：US10818939

    申请日：2004-04-05

    申请人： Thomas Peters ,  Volker Schluter ,  Johannes Grosse ,  Heike Schauerte ,  Andreas Marquardt

    发明人： Thomas Peters ,  Volker Schluter ,  Johannes Grosse ,  Heike Schauerte ,  Andreas Marquardt

    IPC分类号： A61K48/00 ,  C07K14/47 ,  C12N15/12

    CPC分类号： A01K67/0278 ,  A01K2207/15 ,  A01K2217/00 ,  A01K2217/05 ,  A01K2217/072 ,  A01K2227/105 ,  A01K2267/0306 ,  C07K14/47

    摘要： The present invention relates to a non-human vertebrate animal model displaying an alteration in fat metabolism or in the sensitivity towards leptin or insulin, which model bears a mutation in the gene encoding the spinster like 1 protein (Spinl1). The invention also relates to mutant Spinl1 proteins and nucleic acid sequences encoding these proteins. Furthermore, the invention relates to the use of the non-human vertebrate animal model for the identification of diagnostic markers, or as a model for studying the molecular and physiological mechanisms associated with an alteration in fat metabolism or an alteration in the sensitivity towards leptin or insulin, or for the identification and testing of agents useful in the prevention, amelioration, or treatment of the above conditions. Agents, pharmaceutical compositions, and methods for treating the above conditions are likewise described, as are methods for identifying said agents.

    摘要翻译： 本发明涉及显示脂肪代谢改变或瘦素或胰岛素敏感性的非人脊椎动物模型，该模型在编码如1蛋白（Spin1）的纺锤体的基因中具有突变。 本发明还涉及突变Spin1蛋白和编码这些蛋白的核酸序列。 此外，本发明涉及非人类脊椎动物模型用于鉴定诊断标记物的用途，或用作研究与脂肪代谢改变相关的分子和生理机制的模型或对瘦素的敏感性的改变或 胰岛素，或用于鉴定和测试可用于预防，改善或治疗上述病症的药剂。 同样地描述了用于鉴定所述试剂的药剂，药物组合物和用于治疗上述病症的方法。

    Method for detecting biologically active compounds from compound libraries
    16.
    发明授权
    Method for detecting biologically active compounds from compound libraries 失效
    从化合物库检测生物活性化合物的方法

    公开(公告)号：US06214561B1

    公开(公告)日：2001-04-10

    申请号：US08978344

    申请日：1997-11-25

    申请人： Thomas Peters ,  Bernd Meyer

    发明人： Thomas Peters ,  Bernd Meyer

    IPC分类号： G01N3353

    CPC分类号： G01N33/54373 ,  G01R33/4625 ,  Y10T436/24

    摘要： A method for detecting at least one substance (a ligand) present in a compound library using at least one additional substance (a receptor) that binds to the ligand comprises adding to the compound library such a receptor that has substantially higher molecular weight than the ligand to be identified, and performing of such a spectroscopic measurement technique with the mixture, without isolating the receptor-ligand complex, that can detect those dipolar resonance phenomena which occur upon a binding of a receptor to a ligand.

    摘要翻译： 使用结合配体的至少一种另外的物质（受体）检测存在于化合物文库中的至少一种物质（配体）的方法包括向化合物文库添加具有比配体大得多的分子量的受体 并且通过混合物进行这种光谱测量技术，而不分离受体 - 配体复合物，其可以检测在受体与配体结合时发生的那些偶极共振现象。