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11.
公开(公告)号:US20230009601A1
公开(公告)日:2023-01-12
申请号:US17902274
申请日:2022-09-02
Applicant: University of Southampton
Inventor: Austin Taranta , Eirc Numkam Fokoua , Francesco Poletti , David Neil Payne
IPC: G02B6/02
Abstract: An interferometric optical fibre sensor comprises optical fibre defining an optical circuit configured to propagate a first optical wave via an environment in which the optical fibre can be exposed to a stimulus that modifies the first optical wave, and a second optical wave, and to combine the first optical wave and the second optical wave to create an interference signal containing information about the stimulus, wherein optical fibre propagating either or both of the first optical wave and the second optical wave comprises hollow core optical fibre configured to propagate the optical wave or waves by an antiresonant optical guidance effect.
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公开(公告)号:US11517577B2
公开(公告)日:2022-12-06
申请号:US17262915
申请日:2019-07-30
Applicant: NZP UK LIMITED , THE UNIVERSITY OF SOUTHAMPTON
Inventor: Alexander Charles Weymouth-Wilson , Gemma Packer , Bruno Jan Pol Linclau , Dannielle Kydd-Sinclair , Kimberly Ann Watson
IPC: A61K31/64 , A61P1/16 , A61K31/575 , C07J41/00
Abstract: The invention relates to compounds of general formula (I): wherein R2a, R2b, R3a, R3b, R5, Y and R7 are as defined herein are selective agonists at the FXR receptor and are useful for the treatment or prevention of diseases and conditions including nonalcoholic steatohepatitis (NASH); primary biliary cirrhosis; primary sclerosing cholangitis; biliary atresia; cholestatic liver disease; hepatitis C infection; alcoholic liver disease; fibrosis; and liver damage arising from fibrosis.
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公开(公告)号:US20220333233A1
公开(公告)日:2022-10-20
申请号:US17761110
申请日:2020-09-11
Applicant: University of Southampton
Inventor: Kai SUN , Cornelis Hendrik DE GROOT , Otto Lambert MUSKENS
Abstract: A method of forming an optical thin film, comprises providing an assembly comprising a layer of semiconductor material deposited on a substrate, the semiconductor material comprising a compound of at least one metal and a group VI element; depositing a masking layer onto the layer of semiconductor material, the masking layer being patterned to expose one or more regions of the layer of semiconductor material; applying to the assembly a plasma of the group VI element in order to cause indiffusion of the group VI element into the semiconductor material in the exposed regions while the masking layer blocks indiffusion in unexposed regions, the indiffusion causing a reduction in carrier density in the semiconductor material; and removing the masking layer; thereby forming, from the layer of semiconductor material, an optical thin film having a variation in carrier density and corresponding variation in optical properties matching the patterning of the masking layer in a plane parallel to the substrate.
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公开(公告)号:US20220317369A1
公开(公告)日:2022-10-06
申请号:US17220864
申请日:2021-04-01
Applicant: Saudi Arabian Oil Company , University of Southampton
Inventor: Hesham Sakr , Hans Christian Hansen Mulvad , Shaif-ul Alam , Lin Xu , Callum Smith , John Hayes , David Richardson , Francesco Poletti , Damian Pablo San Roman Alerigi , Sameeh Issa Batarseh
IPC: G02B6/032
Abstract: A nested anti-resonant nodeless hollow core fiber (NANF) enables transmission of multi-kilowatt, continuous wave (CW) light beams operating in wavelengths between 1050 nm and 1100 nm provided by single mode lasers. Such a NANF has little loss over kilometer ranges, and can be employed in long distance subsurface applications, such as in the petroleum industry.
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公开(公告)号:US11428865B2
公开(公告)日:2022-08-30
申请号:US16635200
申请日:2018-08-01
Applicant: University of Southampton
Inventor: Gregory Teofil Jasion , Francesco Poletti , Yong Chen , Eric Rodrigue Numakm Fokoua , Thomas David Bradley
IPC: G02B6/02 , C03B37/012 , C03B37/027
Abstract: A hollow core photonic bandgap optical fibre comprises: a cladding comprising capillaries in a hexagonal array and a hollow core formed by excluding a hexagonal group of nineteen capillaries from the centre of the hexagonal array. The core is inflated. A core size ratio is 1.26 or above, defined as a ratio of the core diameter to the cladding diameter normalized to the ratio of the core diameter to the cladding diameter in an undistorted hexagonal array; a first ring ratio is between 0.55 and 2.50, defined as a ratio of the length of radially aligned struts separating the capillaries of the first ring to the length of a strut in an undistorted hexagonal array; and a core node spacing is between 0.60 and 1.90, where defined as a ratio of a strut length around the core of a largest corner capillary and a strut length around the core of a smallest side capillary. The fabrication method comprises four different pressures for the core, corner capillary, side capillary and cladding.
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公开(公告)号:US20220262087A1
公开(公告)日:2022-08-18
申请号:US17618607
申请日:2020-06-12
Inventor: Nikolay Ivanovich ZHELUDEV , Guanghui YUAN , Nikitas PAPASIMAKIS , Vassily SAVINOV
IPC: G06V10/145 , G06V10/60 , G06V10/82 , G06V10/774 , G06V10/10
Abstract: A method of imaging comprises: generating a superoscillatory field from coherent electromagnetic radiation; placing an object in the superoscillatory field; detecting one or more intensity distributions of the superoscillatory field scattered by the object; and determining at least one characteristic of the object from the one or more intensity distributions.
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公开(公告)号:US20220214498A1
公开(公告)日:2022-07-07
申请号:US17605500
申请日:2020-04-24
Applicant: UNIVERSITY OF SOUTHAMPTON
Inventor: David THOMSON , Graham REED , Wei Wei ZHANG , Martin EBERT
Abstract: The invention provides a photonic chip comprising: a silicon substrate, an low refractive index layer above the silicon substrate, and a tapered waveguide above the low refractive index layer, the tapered waveguide having a first height at a first end of the tapered waveguide and a second height at a second end of the tapered waveguide, the second height being greater than the first height, and the tapered waveguide having a bottom surface that is closer to the substrate at the second end than at the first end. The invention further provides a method of manufacturing a photonic chip, the method comprising: providing a wafer comprising a silicon substrate, and an low refractive index layer above the silicon substrate, etching the low refractive index layer to form a tapered trench having a first height at a first end of the tapered trench and a second height at a second end of the tapered trench, the first second height being greater than the second first height, and the tapered trench having a bottom surface that is closer to the substrate at the first second end than at the second first end, and forming a tapered waveguide in the tapered trench.
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公开(公告)号:US11287705B2
公开(公告)日:2022-03-29
申请号:US16637176
申请日:2018-07-19
Applicant: UNIVERSITE DE STRASBOURG , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , UNIVERSITY OF SOUTHAMPTON
Inventor: Thomas M. Heiser , Thomas M. Regrettier , Malgosia Kaczmarek
Abstract: The invention concerns a liquid crystal spatial light modulator (101) comprising: a liquid crystal layer (7); and on at least one side of the liquid crystal layer (7), at least one photovoltaic cell (456), each photovoltaic cell (456) comprising a photosensitive layer (5) comprising electron-donating (D) molecules and electron accepting (A) molecules, each photovoltaic cell (456) being arranged for spontaneous photovoltage under illumination. Electron-donating molecules and electron accepting molecules are preferably blended and form preferably an organic bulk heterojunction layer. The photosensitive layer (5) of each photovoltaic cell (456) is preferably comprised between: —an electron conducting layer (4) arranged for a transfer of an electron from its contacting photosensitive layer (5) easier than a transfer of an electron hole from its contacting photosensitive layer (5), and —an electron hole conducting layer (6) arranged for a transfer of an electron hole from its contacting photosensitive layer (5) easier than a transfer of an electron from its contacting photosensitive layer (5).
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公开(公告)号:US20220073557A1
公开(公告)日:2022-03-10
申请号:US17415216
申请日:2019-12-20
Applicant: NZP UK LIMITED , THE UNIVERSITY OF SOUTHAMPTON
Inventor: Alexander Charles Weymouth-Wilson , Bruno Jan Pol Linclau , Gemma Packer , Joseph Watts , Heather Mortiboys , Oliver Bandmann , Christopher Hastings
Abstract: Compounds of general formula (1): wherein R1, R2 and R3 are as defined herein; are of use in the treatment and prevention of neurodegenerative disorders including Alzheimer's disease and Parkinson's disease.
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公开(公告)号:US20220009028A1
公开(公告)日:2022-01-13
申请号:US17297102
申请日:2019-11-26
Applicant: University of Southampton
Inventor: Peter KAZANSKY , Masaaki SAKAKURA , Lei WANG
IPC: B23K26/0622 , B23K26/073
Abstract: A method of fabricating an optical element comprises providing a substrate of a transparent material; and applying one or more focused femtosecond pulses of laser light with an elliptical polarisation to a volume within the substrate to create at least one nanostructure in the volume.
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