公开(公告)号：US08585130B2

公开(公告)日：2013-11-19

申请号：US13100662

申请日：2011-05-04

Applicant: Vincent Gonin

Inventor： Vincent Gonin

IPC: B60J7/00

CPC classification number: B62D25/08 ,  B60J5/101 ,  B60R19/12 ,  B60R19/22 ,  B62D21/152

Abstract: This rear-end element (2) for motor vehicle includes a carrier structural element (6) forming an energy-absorbing element after impact, and a carrier structural frame (8). At least the carrier structural element (6) has a cellular structure formed of cells (30, 32) extending longitudinally through the carrier structural element (6) between a back face and a front face of the carrier structural element (6) and opening onto the back and/or front face of the carrier structural element (6). A rear end (44) which includes the rear-end element (2).

Abstract translation: 用于机动车辆的后端元件（2）包括在撞击之后形成能量吸收元件的载体结构元件（6）和载体结构框架（8）。 至少载体结构元件（6）具有由在载体结构元件（6）的背面和前表面之间纵向延伸穿过载体结构元件（6）的孔（30,32）形成的多孔结构， 载体结构元件（6）的后表面和/或前表面。 包括后端元件（2）的后端（44）。

公开(公告)号：US20110156414A1

公开(公告)日：2011-06-30

申请号：US12977539

申请日：2010-12-23

Applicant: Vincent GONIN ,  Laurent DROZ BARTHOLET ,  Julien DUFEE

Inventor： Vincent GONIN ,  Laurent DROZ BARTHOLET ,  Julien DUFEE

IPC: B60R19/24

CPC classification number: B62D25/084 ,  B60R19/12 ,  B60R19/24 ,  B60R2019/186 ,  B62D21/152

Abstract: This bumper assembly is adapted for a motor vehicle having a structure including a pair of upper side members (6) and a pair of lower side members (8). It includes an energy absorbing panel (12) having at least two columns (16) each provided to bear on the ends of an upper side member (6) and a lower side member (8) and a beam (18) extending transversely between the columns (16). According to one embodiment, the bumper assembly includes a plate (36) doubling the beam (18) such that the beam (18) is compressed between a frontal face (36a) of the plate (36) in case of impact. The device is applicable to front or rear bumpers.

Abstract translation: 该保险杠组件适用于具有包括一对上侧构件（6）和一对下侧构件（8）的结构的机动车辆。 它包括能量吸收板（12），其具有至少两列（16），每列设置成承载在上侧构件（6）和下侧构件（8）的端部上，横梁（18）横向延伸 列（16）。 根据一个实施例，保险杠组件包括使梁（18）加倍的板（36），使得在碰撞的情况下，梁（18）在板（36）的正面（36a）之间被压缩。 该设备适用于前保险杠或后保险杠。

公开(公告)号：US20110115241A1

公开(公告)日：2011-05-19

申请号：US12945667

申请日：2010-11-12

Applicant: VINCENT GONIN

Inventor： VINCENT GONIN

IPC: B60R19/03 ,  B60R19/36 ,  B62D25/08

CPC classification number: B62D25/084 ,  B60R19/03 ,  B60R19/12 ,  B60R2019/184 ,  B60R2019/1846 ,  B60R2019/1866

Abstract: This assembly is of the type comprising at least two pairs of front longitudinal members (12, 16) and supporting and attachment plates (20) positioned at the front ends of the longitudinal members (12, 16), a front bumper shield (8) comprising a one-piece frame (22) in plastic material formed with an upper bumper beam (24) and a lower bumper beam (26) and two uprights (28) connecting the upper (24) and lower (26) bumper beams, the shield (8) further comprising an additional beam (40) made with the frame (22) in the same material, said additional beam (40) comprising means for attaching at least one piece of auxiliary equipment of the motor vehicle.

Abstract translation: 该组件是包括至少两对前纵向构件（12,16）和位于纵向构件（12,16）的前端处的支撑和附接板（20）的类型，前保险杠罩（8） 包括塑料材料的一体式框架（22），其形成有连接上部（24）和下部（26）缓冲梁的上部缓冲梁（24）和下部缓冲梁（26）和两个立柱（28） 所述附加梁（40）包括用于附接所述机动车辆的至少一个辅助设备的装置（40）。

公开(公告)号：US20100127533A1

公开(公告)日：2010-05-27

申请号：US12624673

申请日：2009-11-24

Applicant: Vincent GONIN

Inventor： Vincent GONIN

IPC: B62D25/08

CPC classification number: B60R19/18 ,  B60R19/12 ,  B60R2019/1833

Abstract: This assembly comprises a plastics material structural frame (2) comprising at least a lower cross member (8) and vertical struts (10, 12), each of said struts (10, 12) forming, over at least a portion of its height, a deformable energy absorption component (14), the module further comprising a plastics material shield (4) formed so as to match the shape of a shield skin (56) and arranged against the structural frame (2), said shield (4) comprising an upper cross member (34) and a lower cross member (36) interconnected via vertical connecting beams (38). The upper (34) and lower (36) cross members and the connecting beams (38) comprise a plurality of ribs (48) which form cells (50) in said cross members (34, 36) and said beams (38), at least some of said cells (50) passing through the shield (4).

Abstract translation: 该组件包括至少包括下横向构件（8）和垂直支柱（10,12）的塑料材料结构框架（2），每个所述支柱（10,12）在其高度的至少一部分上形成， 可变形能量吸收部件（14），所述模块还包括形成为与护罩（56）的形状相匹配并且抵靠结构框架（2）布置的塑料材料护罩（4），所述护罩（4）包括 通过垂直连接梁（38）互连的上横向构件（34）和下横向构件（36）。 上部（34）和下部（36）横向构件和连接梁（38）包括在所述横向构件（34,36）和所述梁（38）中形成室（50）的多个肋（48） 至少一些所述电池（50）穿过屏蔽件（4）。

公开(公告)号：US20090315343A1

公开(公告)日：2009-12-24

申请号：US12486219

申请日：2009-06-17

Applicant: Vincent GONIN

Inventor： Vincent GONIN

IPC: B60R19/02

CPC classification number: B60R19/12 ,  B60R19/26 ,  B60R2019/186 ,  B62D25/084

Abstract: A front shock-absorber assembly for a motor vehicle includes, at each of the right-hand and left-hand sides thereof, at least a lower longitudinal structural element (6, 7) and an upper longitudinal structural element (4, 5). The shock-absorber assembly includes a high-energy impact absorption structure (12) which includes an elongate right-hand plate (18) and left-hand plate (19), each plate being fixedly joined to a lower longitudinal element and an upper longitudinal element located at the same side of the vehicle; and a deformable right-hand element (30) and left-hand element (31) for absorbing medium-energy impacts, a rear surface of a deformable element moving into abutment against the majority of a front surface of an associated plate.

Abstract translation: 用于机动车辆的前部减震器组件在其右侧和左侧的每一个处包括至少一个下部纵向结构元件（6,7）和上部纵向结构元件（4,5）。 减震器组件包括高能冲击吸收结构（12），其包括细长的右手板（18）和左手板（19），每个板固定地连接到下纵向元件和上纵向 元件位于车辆的同一侧; 和用于吸收中等能量冲击的可变形的右手元件（30）和左手元件（31），可变形元件的后表面与相关联的板的前表面相抵靠。

公开(公告)号：US09346425B2

公开(公告)日：2016-05-24

申请号：US13988916

申请日：2011-11-22

Applicant: Abla Steinmetz ,  Laurent Droz Bartholet ,  Vincent Gonin ,  Marie-Pierre Buron

Inventor： Abla Steinmetz ,  Laurent Droz Bartholet ,  Vincent Gonin ,  Marie-Pierre Buron

IPC: B60R19/34 ,  F16F7/12

CPC classification number: B60R19/34 ,  F16F7/121

Abstract: The energy-absorption device (5) for a motor vehicle that comprises: a first energy-absorption member (50), in a first plastic material, provided so as to perfectly deform under the effect of an impact of given energy by absorbing a first portion of the energy of said impact; a second energy-absorption member (52), in a second plastic material different from the first plastic material, provided so as to plastically deform under the effect of said impact of given energy by absorbing a second portion of the energy of said impact; the first and second energy-absorption members (50, 52) being conformed so that the energy-absorption device (5) has a total intrusion-resisting force comprised between 75 and 200 kN, at any temperature comprised between −30° C. and 80° C.

Abstract translation: 一种用于机动车辆的能量吸收装置（5），包括：第一塑料材料中的第一能量吸收构件（50），其被设置为在给定能量的冲击的作用下完全变形， 所述冲击的能量的一部分; 在与所述第一塑料材料不同的第二塑料材料中设置的第二能量吸收构件（52），其被设置为通过吸收所述冲击的能量的第二部分在给定能量的冲击的作用下塑性变形; 所述第一和第二能量吸收构件（50,52）被构造成使得所述能量吸收装置（5）具有在75和200kN之间的总的抗入侵力，在-30℃和 80℃

公开(公告)号：US20140042758A1

公开(公告)日：2014-02-13

申请号：US13988934

申请日：2011-11-21

Applicant: Marie-Pierre Buron ,  Philippe Compagnon ,  Abla Steinmetz ,  Vincent Gonin

Inventor： Marie-Pierre Buron ,  Philippe Compagnon ,  Abla Steinmetz ,  Vincent Gonin

IPC: F16F7/12 ,  F16F7/00

CPC classification number: F16F7/121 ,  B60R19/03 ,  B60R19/34 ,  B62D21/152 ,  B62D25/085 ,  B62D29/005 ,  F16F7/003 ,  F16F7/124

Abstract: The invention relates to an energy absorption device for a motor vehicle, said device comprising a structure provided so as to plastically deform under the effect of an impact of a given energy, the structure being made of a matrix of a ductile plastic material and high-tenacity fibers embedded in the matrix, the majority of the fibers having a length of between 0.1 and 10 mm, and the material comprising between 2 and 10 wt % of high-tenacity fibers.

Abstract translation: 本发明涉及一种用于机动车辆的能量吸收装置，所述装置包括设置成在给定能量的冲击的作用下塑性变形的结构，该结构由延性塑料材料和高韧性塑料材料的基体制成， 嵌入基质中的韧性纤维，大部分纤维的长度为0.1至10毫米，该材料包含2至10重量％的高强度纤维。

公开(公告)号：US08215705B2

公开(公告)日：2012-07-10

申请号：US12486219

申请日：2009-06-17

Applicant: Vincent Gonin

Inventor： Vincent Gonin

IPC: B60R19/02

CPC classification number: B60R19/12 ,  B60R19/26 ,  B60R2019/186 ,  B62D25/084

Abstract: A front shock-absorber assembly for a motor vehicle includes, at each of the right-hand and left-hand sides thereof, at least a lower longitudinal structural element (6, 7) and an upper longitudinal structural element (4, 5). The shock-absorber assembly includes a high-energy impact absorption structure (12) which includes an elongate right-hand plate (18) and left-hand plate (19), each plate being fixedly joined to a lower longitudinal element and an upper longitudinal element located at the same side of the vehicle; and a deformable right-hand element (30) and left-hand element (31) for absorbing medium-energy impacts, a rear surface of a deformable element moving into abutment against the majority of a front surface of an associated plate.

Abstract translation: 用于机动车辆的前部减震器组件在其右侧和左侧的每一个处包括至少一个下部纵向结构元件（6,7）和上部纵向结构元件（4,5）。 减震器组件包括高能冲击吸收结构（12），其包括细长的右手板（18）和左手板（19），每个板固定地连接到下纵向元件和上纵向 元件位于车辆的同一侧; 和用于吸收中等能量冲击的可变形的右手元件（30）和左手元件（31），可变形元件的后表面与相关联的板的前表面相抵靠。

公开(公告)号：US20100244472A1

公开(公告)日：2010-09-30

申请号：US12641749

申请日：2009-12-18

Applicant: Vincent GONIN ,  Julien DUFEE ,  Laurent DROZ BARTHOLET

Inventor： Vincent GONIN ,  Julien DUFEE ,  Laurent DROZ BARTHOLET

IPC: B60R19/34 ,  B60R19/02

CPC classification number: B62D25/084 ,  B60R19/12 ,  B60R2019/1846

Abstract: The assembly is of the type comprising two pairs of front longitudinal members of a chassis of a motor vehicle and support and fixing mounting plates arranged at the front ends of the longitudinal members and comprising a front bumper shield comprising a one-piece plastics material frame consisting of an upper bumper beam and a lower bumper beam and two vertical members connecting the upper and lower bumper beams, the vertical members of the frame being configured to act as impact absorbers and fixed resting directly against the mounting plates.

Abstract translation: 组件是包括机动车辆的底盘的两对前纵向构件的类型，以及布置在纵向构件的前端处的支撑和固定安装板，并且包括前保险杠罩，其包括一体式塑料材料框架， 上缓冲梁和下保险杠梁以及连接上保险杠梁和下缓冲梁的两个垂直构件，框架的垂直构件构造成用作冲击吸收器并且固定地直接靠在安装板上。

公开(公告)号：US20130195863A1

公开(公告)日：2013-08-01

申请号：US13823907

申请日：2010-09-28

Applicant: Philippe Clezardin ,  Vincent Gonin ,  Richard Bachelier ,  Edith Bonnelye

Inventor： Philippe Clezardin ,  Vincent Gonin ,  Richard Bachelier ,  Edith Bonnelye

IPC: A61K39/395 ,  A61K31/7105 ,  A61K38/17 ,  A61K48/00 ,  G01N33/68 ,  C12Q1/68

CPC classification number: A61K39/3955 ,  A61K31/7105 ,  A61K38/1703 ,  A61K38/1709 ,  A61K48/005 ,  C07K14/4702 ,  C07K16/30 ,  C07K2319/30 ,  C12N15/1138 ,  C12N15/115 ,  C12N2310/14 ,  C12N2310/16 ,  C12N2310/531 ,  C12Q1/6876 ,  G01N33/57407 ,  G01N33/6893 ,  G01N2800/10 ,  G01N2800/108

Abstract: The invention relates to methods and pharmaceutical compositions for the treatment of bone density related diseases. More particularly, the present invention relates to a ROBO1 modulator for use in a method for the treatment of a bone mineral density related disease in a subject. In a particular embodiment the ROBO1 modulator is selected from the group consisting of small organic molecules, antibodies, aptamers or polypeptides. In another particular embodiment said bone mineral density related disease is selected from the group consisting of ghosal hematodiaphyseal dysplasia syndrome (GHDD), osteoporosis, osteoporosis associated to pseudoglioma, osteoporosis and oculocutaneous hypopigmentation syndrome, osteoporosis due to endocrinological dysfunction, osteogenesis imperfecta osteopenia, Paget's disease, osteomyelitis, hypercalcemia, osteonecrosis, hyperparathyroidism, lytic bone metastases, periodontitis, bone loss due to immobilization and osteoporosis associated with a disease selected from the group consisting of cachexia, anorexia, alopecia, rheumatoid arthritis, psoriatic arthritis, psoriasis, and inflammatory bowel disease.

Abstract translation: 本发明涉及用于治疗骨密度相关疾病的方法和药物组合物。 更具体地，本发明涉及用于治疗受试者中与骨矿物质密度相关的疾病的方法中的ROBO1调节剂。 在一个具体实施方案中，ROBO1调节剂选自小有机分子，抗体，适体或多肽。 在另一个具体实施方案中，所述骨矿物质密度相关疾病选自由下列组成的组：颅内血肿发育不良综合征（GHDD），骨质疏松症，与假性胶质瘤相关的骨质疏松症，骨质疏松症和眼部色素沉着不全综合征，由内分泌功能障碍引起的骨质疏松症，成骨不全的骨质减少症，佩吉特氏病 骨髓炎，高钙血症，骨坏死，甲状旁腺功能亢进，溶骨转移，牙周炎，由固定引起的骨丢失和与选自恶病质，厌食症，脱发，类风湿性关节炎，牛皮癣关节炎，牛皮癣和炎症性肠病的疾病相关的骨质疏松症 。