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42 条记录 (耗时 0.025 秒)

    Method and composition for resuscitation
    11.
    发明授权
    Method and composition for resuscitation 失效
    复苏的方法和组成

    公开(公告)号：US07387798B2

    公开(公告)日：2008-06-17

    申请号：US11234906

    申请日：2005-09-26

    申请人： Yanming Wang

    发明人： Yanming Wang

    IPC分类号： A61K33/42 ,  A61K38/00 ,  A61K31/70 ,  A61K31/41 ,  A61K31/34

    CPC分类号： A61K31/34 ,  A61K31/341 ,  A61K31/433 ,  A61K31/7076 ,  A61K38/17 ,  A61K38/28 ,  A61K38/38 ,  A61K38/39 ,  A61K45/06

    摘要： The key obstacle for current resuscitation is the acutely limited time window. The major reason for the limited time window is that the brain and spinal cord are extremely vulnerable to hypoxic-ischemic insult. A method and a lymph-like fluid composition for resuscitation of cardiac arrest are provided. The method includes steps of inhibiting CSF production, removing CSF, replacing the CSF with invented lymph-like fluid composition plus conventional CPR. The lymph-like fluid composition includes polypeptides, insulin, elevated magnesium concentration and ATP in artificial CSF.

    摘要翻译： 目前复苏的关键障碍是急剧限制的时间窗口。 有限的时间窗口的主要原因是脑和脊髓极易受到缺氧缺血性侮辱。 提供了用于心脏骤停复苏的方法和淋巴样液体组合物。 该方法包括抑制CSF产生，去除CSF，用发明的淋巴样液体组合物加常规CPR代替CSF的步骤。 淋巴样液体组合物包括人造脑脊液中的多肽，胰岛素，升高的镁浓度和ATP。

    COMPOSITIONS AND METHODS FOR IN VIVO IMAGING OF MYELIN IN THE PERIPHERAL NERVOUS SYSTEM
    15.
    发明申请
    COMPOSITIONS AND METHODS FOR IN VIVO IMAGING OF MYELIN IN THE PERIPHERAL NERVOUS SYSTEM 有权
    在外周神经系统中血浆中的髓鞘成像的组合物和方法

    公开(公告)号：US20120093727A1

    公开(公告)日：2012-04-19

    申请号：US13284288

    申请日：2011-10-28

    申请人： YANMING WANG ,  Chunying Wu

    发明人： YANMING WANG ,  Chunying Wu

    IPC分类号： A61K51/04 ,  A61K49/00

    CPC分类号： A61K49/0021

    摘要： A method of detecting and/or labeling myelin in an animal's peripheral nervous system tissue includes administering to the animal a fluorescent stilbenzene derivative and visualizing the animal's peripheral nervous system tissue using an in vivo imaging modality.

    摘要翻译： 在动物的周围神经系统组织中检测和/或标记髓磷脂的方法包括向动物施用荧光苯并苯衍生物并使用体内成像模式使动物的周围神经系统组织可视化。

    Composition and treatment method for brain and spinal cord injuries
    18.
    发明授权
    Composition and treatment method for brain and spinal cord injuries 失效
    脑和脊髓损伤的组成和治疗方法

    公开(公告)号：US06683066B2

    公开(公告)日：2004-01-27

    申请号：US09962009

    申请日：2001-09-24

    申请人： Yanming Wang

    发明人： Yanming Wang

    IPC分类号： A61K3578

    CPC分类号： A61K31/737 ,  A61K31/00 ,  A61K31/355 ,  A61K31/56 ,  A61K31/685 ,  A61K35/60 ,  A61K36/48 ,  A61K2300/00

    摘要： After interruption of blood supply to central nervous system tissue, cerebral edema sets in. It has been shown that restoring blood flow to injured areas of the central nervous system after the onset of edema does not result in blood reperfusing the tissue. A composition and method for treating injured central nervous tissue, or preventing injury to central nervous system tissue is provided. The composition is generally an amphipathic lipid in an oil solution. The method provides for withdrawing cerebrospinal fluid from the subarachnoid spaces around the tissue to be treated or protected, and replacing that fluid with an approximately equivalent volume of the amphipathic lipid in oil composition. The treatment can be augmented with agents that suppress production of cerebrospinal fluid, or with other known agents.

    摘要翻译： 在中枢神经系统组织供血中断后，脑水肿发生。已经表明，水肿发作后恢复中枢神经系统受损区域的血流不会导致血液再灌注组织。 提供了一种治疗中枢神经系统损伤的组合物和方法，也可防止对中枢神经系统组织的损伤。 组合物通常是油溶液中的两亲性脂质。 该方法提供从待治疗或保护的组织周围的蛛网膜下腔中取出脑脊髓液，并用油组合物中大约相当体积的两亲脂质代替该液体。 可以用抑制脑脊液产生的药物或其它已知药物来增强治疗。