公开(公告)号：US20160374838A1

公开(公告)日：2016-12-29

申请号：US14754479

申请日：2015-06-29

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Alexander J. Sheehy ,  Chad J. Abunassar

IPC: A61F2/915

CPC classification number: A61F2/915 ,  A61F2002/91558 ,  A61F2002/91566 ,  A61F2210/0004 ,  A61F2210/0076 ,  A61F2250/0067 ,  A61L31/06 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/606 ,  A61L2300/608 ,  A61L2420/02 ,  A61L2420/08 ,  C08L67/04

Abstract: Stents including a poly(D,L-lactide)(PDLLA)-based scaffold and PDLLA based therapeutic layer are disclosed. The PDLLA based scaffold may be amorphous and may include a primer layer. Methods of applying the PDLLA-based coating to the scaffold are disclosed with solvent processing methods using a solvent blend are also disclosed. Methods of removing residual solvent from a PDLLA-base coating that also condition the scaffold are disclosed. Methods of treating restenosis that release drugs to prevent restenosis without interfering with the natural positive remodeling of a vessel are disclosed.

Abstract translation: 公开了包含基于聚（D，L-丙交酯）（PDLLA）的支架和基于PDLLA的治疗层的支架。 基于PDLLA的支架可以是无定形的，并且可以包括底漆层。 公开了使用溶剂共混物的溶剂处理方法将基于PDLLA的涂层施用于支架的方法。 公开了从处于支架状态的PDLLA基底涂层除去残余溶剂的方法。 公开了治疗释放药物以预防再狭窄而不干扰血管的天然阳性重塑的再狭窄的方法。

公开(公告)号：US20160081827A1

公开(公告)日：2016-03-24

申请号：US14859170

申请日：2015-09-18

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Rommel Lumauig ,  Stephen D. Pacetti ,  Ni Ding ,  Joel Harrington ,  Xiao Ma ,  James P. Oberhauser ,  Jill McCoy ,  Chad J. Abunassar ,  Senthil Eswaran ,  Diem Ta

IPC: A61F2/915 ,  B29C71/02 ,  A61F2/844 ,  C08G63/08

CPC classification number: A61F2/915 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2230/0069 ,  A61L31/06 ,  A61L31/14 ,  A61L31/148 ,  B29C71/0009 ,  B29C71/02 ,  B29C2035/046 ,  B29C2035/048 ,  B29C2035/0811 ,  B29C2035/0822 ,  B29C2035/0855 ,  B29C2035/0861 ,  B29C2071/022 ,  B29K2067/046 ,  B29K2995/006 ,  B29L2031/7534 ,  C08G63/08 ,  C08L67/04

Abstract: Methods are disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter.

Abstract translation: 公开的方法包括当支架从卷曲状态展开到展开状态（例如标称展开直径）时，热处理支架以增加支架的径向强度。 热处理可以进一步维持或增加支架在膨胀超过公称直径时的膨胀能力。

公开(公告)号：US20130304195A1

公开(公告)日：2013-11-14

申请号：US13942310

申请日：2013-07-15

Applicant: Abbott Cardiovascular Systems, Inc.

Inventor： Chad J. Abunassar

IPC: A61F2/89

CPC classification number: A61F2/89 ,  A61F2/01 ,  A61F2/24 ,  A61F2/915 ,  A61F2002/91558 ,  A61F2002/91566

Abstract: An endoprosthesis for delivery in a body lumen can be configured to inhibit structural fatigue, crack formation, and elastic recoil while providing improved crimping and expansion uniformity and radial strength. As such, the endoprosthesis can include at least one multi-stage crest element connecting adjacent bar arms. The multi-stage crest element and, optionally, the connection or transition between the multi-stage crest element and the bar arms can form a plurality of undulations or curves to improve the distribution of the strains experienced by the endoprosthesis. The improved strain distribution can improve the structural integrity and prevent failure of the endoprosthesis.

Abstract translation: 用于在体腔内输送的内用假体可以被配置为抑制结构疲劳，裂纹形成和弹性反冲，同时提供改进的卷曲和膨胀均匀性和径向强度。 因此，内假体可以包括连接相邻的杆臂的至少一个多级顶部元件。 多级顶部元件以及可选地，多级顶部元件和杆臂之间的连接或过渡可以形成多个起伏或曲线，以改善内置假体经历的应变的分布。 改善的应变分布可以改善结构完整性并防止内假体的失效。

公开(公告)号：US20130226283A1

公开(公告)日：2013-08-29

申请号：US13846186

申请日：2013-03-18

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： Chad J. Abunassar ,  Tanya B. Schikorr ,  Laura M. Kalvass ,  Erik D. Eli ,  Diem U. Ta

IPC: A61F2/89

CPC classification number: A61F2/89 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2002/91583 ,  A61F2230/0013 ,  A61F2230/0054 ,  A61F2250/0037

Abstract: The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for an intravascular stent having a plurality of cylindrical rings connected by links. The links between adjacent rings provide axial strength when subjected to longitudinal compressive forces.

公开(公告)号：US11135074B2

公开(公告)日：2021-10-05

申请号：US15785368

申请日：2017-10-16

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Syed Hossainy ,  Chad J. Abunassar ,  Michael Huy Ngo ,  Erik David Eli ,  Santosh V. Prabhu ,  Mikael Trollsas ,  Richard Rapoza

IPC: A61F2/915 ,  B29C55/26 ,  A61L31/06 ,  B29L31/00 ,  B29C69/00 ,  B29C55/24 ,  A61F2/958

Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings.

公开(公告)号：US10278844B2

公开(公告)日：2019-05-07

申请号：US15688486

申请日：2017-08-28

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Rommel Lumauig ,  Stephen D. Pacetti ,  Ni Ding ,  Joel Harrington ,  Xiao Ma ,  James P. Oberhauser ,  Jill McCoy ,  Chad J. Abunassar ,  Senthil Eswaran ,  Diem Ta

IPC: A61F2/915 ,  C08G63/08 ,  B29C71/02 ,  A61L31/06 ,  A61L31/14 ,  B29C71/00 ,  B29K67/00 ,  B29L31/00 ,  B29C35/04 ,  B29C35/08

Abstract: Methods are disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter.

公开(公告)号：US09908297B2

公开(公告)日：2018-03-06

申请号：US14831693

申请日：2015-08-20

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Chad J. Abunassar ,  Diem U. Ta ,  Richard J. Rapoza

IPC: A61F2/89 ,  B29C69/00 ,  A61F2/915 ,  B29C49/42 ,  B29L31/00 ,  A61F2/91

CPC classification number: B29C69/001 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91575 ,  A61F2230/0006 ,  A61F2250/0036 ,  A61F2250/0098 ,  B29C49/4268 ,  B29C2793/0063 ,  B29L2031/7546

Abstract: A scaffold strut is shaped to improve hemocompatibility. The scaffold is made from a tube having variable wall thickness. Methods are disclosed for modifying the thickness of the tube in such a way as to achieve a reduced hemodynamic profile, but without significantly affecting strength properties in areas where stress concentrations exist when the scaffold is loaded.