公开(公告)号：US10808264B2

公开(公告)日：2020-10-20

申请号：US16032206

申请日：2018-07-11

Applicant: AJINOMOTO CO., INC.

Inventor： Yasuaki Takakura ,  Keiko Danjo ,  Keita Fukui ,  Sayaka Asari ,  Takuto Ono

IPC: C12P7/24

Abstract: A method for producing benzaldehyde is provided. Benzaldehyde is produced from L-phenylalanine or a carbon source by using microorganism(s) having amino acid deaminase, 4-hydroxymandelate synthase, (S)-mandelate dehydrogenase, and benzoylformate decarboxylase.

公开(公告)号：US20190249205A1

公开(公告)日：2019-08-15

申请号：US16392756

申请日：2019-04-24

Applicant: AJINOMOTO CO., INC.

Inventor： Benjamin Mijts ,  Christine Roche ,  Peter Kelly ,  Sayaka Asari ,  Keita Fukui ,  Miku Toyazaki

IPC: C12P7/24 ,  C12N1/20 ,  C12N9/10 ,  C12N9/88 ,  C12N9/02 ,  C12N9/04

CPC classification number: C12P7/24 ,  C12N1/20 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/0069 ,  C12N9/0073 ,  C12N9/1007 ,  C12N9/1085 ,  C12N9/88 ,  C12P7/22 ,  C12P7/42 ,  C12Y101/01001 ,  C12Y101/01025 ,  C12Y102/99007 ,  C12Y113/11003 ,  C12Y114/13082 ,  C12Y201/01015 ,  C12Y205/01054 ,  C12Y402/0101 ,  C12Y402/01118 ,  C12Y402/03004

Abstract: A method for producing an objective substance such as vanillin and vanillic acid is provided. An objective substance is produced from a carbon source or a precursor of the objective substance by using a microorganism having an objective substance-producing ability, which microorganism has been modified so that the activity of an L-cysteine biosynthesis enzyme is increased.

公开(公告)号：US20190241914A1

公开(公告)日：2019-08-08

申请号：US16392776

申请日：2019-04-24

Applicant: AJINOMOTO CO., INC.

Inventor： Benjamin Mijts ,  Christine Roche ,  Peter Kelly ,  Sayaka Asari ,  Miku Toyazaki ,  Keita Fukui

IPC: C12P7/42

CPC classification number: C12P7/42 ,  C12P7/22 ,  C12P7/24 ,  C12P13/001 ,  C12P13/12 ,  C12P17/10 ,  C12P19/40

Abstract: A method for producing an objective substance such as vanillin and vanillic acid is provided. An objective substance is produced from a carbon source or a precursor of the objective substance by using a microorganism having an objective substance-producing ability, which microorganism has been modified so that the activity of NCgl2048 protein is reduced.

公开(公告)号：US20180334693A1

公开(公告)日：2018-11-22

申请号：US15982623

申请日：2018-05-17

Applicant: AJINOMOTO CO., INC.

Inventor： Christine Roche ,  Benjamin Mijts ,  Peter Kelly ,  Matthew Davis ,  Sayaka Asari ,  Keita Fukui ,  Miku Toyazaki

IPC: C12P7/42 ,  C12P13/12 ,  C12R1/15 ,  C12R1/19 ,  C12N15/77 ,  C12N9/10 ,  C12N9/78 ,  C12N9/88

CPC classification number: C12P7/42 ,  C12N9/1003 ,  C12N9/78 ,  C12N9/88 ,  C12N15/77 ,  C12P7/22 ,  C12P7/24 ,  C12P13/12 ,  C12R1/15 ,  C12R1/19 ,  C12Y201/02003 ,  C12Y305/0401 ,  C12Y403/01017

Abstract: A method for producing an objective substance such as vanillin and vanillic acid is provided. An objective substance is produced from a carbon source or a precursor of the objective substance by using a microorganism having an objective substance-producing ability, which microorganism has been modified so as to have a specific feature, such as a reduced activity of AICAR formyltransferase/IMP cyclohydrolase, an increased activity of 3-PGDH, and/or a reduced activity of L-serine deaminase.