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公开(公告)号:US20210154098A1
公开(公告)日:2021-05-27
申请号:US16953059
申请日:2020-11-19
Applicant: AKTIVAX, Inc.
Inventor: Amir Genosar
Abstract: A closed transfer system for transferring metered dose of a beneficial agent from a flexible primary container to a second reservoir or to a patient. The system can be configured to transfer multiple doses.
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公开(公告)号:US20180072480A1
公开(公告)日:2018-03-15
申请号:US15495882
申请日:2017-04-24
Applicant: Aktivax, Inc.
Inventor: Amir Genosar
CPC classification number: B65D81/32 , A61J1/201 , A61J1/2024 , A61J1/2027 , A61J1/2089 , A61J1/2093 , A61M5/2425 , A61M5/2448 , A61M5/2455 , A61M5/322 , A61M5/3234 , A61M2005/3224 , A61M2005/323 , B65D25/08 , B65D81/3205 , B65D81/3233 , B65D81/3266
Abstract: A package comprising a container for holding a first substance, and a product insert for holding a second substance, at least partially inserted info said container, and where the first product and the second product can be allowed to merge by external manipulation of said package. Packaged products and methods are also provided.
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公开(公告)号:US20250115414A1
公开(公告)日:2025-04-10
申请号:US18682574
申请日:2022-08-11
Applicant: AKTIVAX, INC.
Inventor: Amir Genosar
IPC: B65D83/38 , B01D63/08 , B65D83/206
Abstract: A pressure vessel with an interior adapted to contain a pressurized substance is provided. The pressure vessel includes a membrane including an interior surface exposed to the interior of the pressure vessel, the membrane adapted to hermetically seal the pressure vessel in an intact state and to release the pressurized substance in a ruptured state. The pressure vessel further includes an actuating rod coupled to and extending from an exterior surface of the membrane on an opposite side of the membrane relative to the interior surface, the actuating rod adapted to transition the membrane from the intact state to the ruptured state in response to receiving a transverse force.
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公开(公告)号:US20240366472A1
公开(公告)日:2024-11-07
申请号:US18687517
申请日:2022-08-30
Applicant: AKTIVAX, INC.
Inventor: Amir Genosar , Greg Langley , Rick Levaughn , Andrew Fish , Eric Sugano , Erik Hoenes , Dean Carpenter , Dominic Aiello , Justin Chatroop , Nick Lucarelli
Abstract: A package arrangement is provided. The package arrangement includes a package including a compartment defined by a wall. The wall includes a flexible portion. The compartment stores a beneficial agent. The compartment at least partially collapses in response to applied pressure. The compartment is hermetically sealed in a storage configuration. The package includes a rigid insert including a conduit in fluid communication with the compartment. The rigid insert is positioned inside the compartment and includes an insert coupling portion. The package arrangement further includes a rigid frame containing part of the compartment within the rigid frame. The rigid frame includes a frame coupling portion. The insert coupling portion exerts pressure on the frame coupling portion through the flexible portion to restrict motion of the rigid insert relative to the rigid frame. The flexible portion hermetically seals a proximal portion of the conduit in the storage configuration.
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公开(公告)号:US20230373707A1
公开(公告)日:2023-11-23
申请号:US18319295
申请日:2023-05-17
Applicant: Aktivax, Inc.
Inventor: Amir Genosar
CPC classification number: B65D83/0055 , B65D77/06 , B65D47/12 , B65D35/14 , B65D79/0084
Abstract: The disclosure provides a packaging system to store a beneficial agent including a primary package with a molded component. The molded component may have a compartment with a flexible wall enclosing a storage volume and a rigid section configured to connect to a secondary package such that the compartment is contained therewithin. The flexible wall may collapse to deplete a beneficial agent from the storage volume through a dispensing port. The flexible wall may be a web material including a monolayer web or multilayer web, and may incorporate a film, a foil, an adhesive, a polymer layer, a metallic layer, and/or a metal oxide layer. The molded component may be a co-molded component formed of a first material and a second material, the first material being molded into a form and joined to a second material. The molded component may be a unitary molded component which consists of one material.
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公开(公告)号:US20220088310A1
公开(公告)日:2022-03-24
申请号:US17510078
申请日:2021-10-25
Applicant: Aktivax, Inc.
Inventor: Amir Genosar
Abstract: A dispensing device for use with a beneficial agent has a dispensing package, a dispenser disposed on an end portion of the dispensing package, and an actuator movably disposed along at least a portion of the package between a pre-dispensing state and a dispensing state. One arrangement also provides a beneficial agent dispenser having a dispensing port, an elongate portion and a plunger that is movably disposed relative to a tubular wall of the elongate portion during a dispensing stroke to partially penetrate a separable barrier and expel the beneficial agent through the dispensing port.
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公开(公告)号:US20210402097A1
公开(公告)日:2021-12-30
申请号:US17360850
申请日:2021-06-28
Applicant: Aktivax, Inc.
Inventor: Amir Genosar , Matthew Gilbert Seehausen , Jason William Fox , Richard Wayne LeVaughn , Andrew David Fish , Eric William Sugano
Abstract: Parenteral delivery of a beneficial agent using an auto-injector configured for reduction of forces acting on a primary container for the beneficial agent during activation of the auto-injector. The primary container may be disposed within a pressure chamber of the auto-injector such that an increased pressure within the pressure chamber during activation is applied to a stopper of the primary container and an external surface of a sidewall of the primary container. In turn, a pressure differential between a containment volume of the primary container and the pressure chamber may be reduced or eliminated. In turn, forces acing on the primary container in response to the pressure increase in the pressure container may be reduced or eliminated. Configurations are also provided for improved relative movement between a stopper and a sidewall of the primary container for more reliable injection.
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公开(公告)号:US10716901B2
公开(公告)日:2020-07-21
申请号:US15517129
申请日:2015-12-05
Applicant: Aktivax, Inc.
Inventor: Amir Genosar
Abstract: An auto-injector operable in a single activation step. The auto-injector is automatically armed when removed from its carrying receptacle. The auto-injector may be prefilled with more than one constituent of a beneficial agent, stored in separated compartments, in such an arrangement that the compartments will automatically merge when the auto-injector is removed from its carrying receptacle.
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公开(公告)号:US20180346232A1
公开(公告)日:2018-12-06
申请号:US15777990
申请日:2016-11-23
Applicant: AKTIVAX, INC.
Inventor: Amir Genosar
CPC classification number: B65D81/32 , A61M5/2053 , B63C9/19 , B65D25/08 , F41B11/62
Abstract: Several pressure cartridges and activation mechanism arrangements are disclosed which are configured to use less manual force to rupture the cartridge than current pressure cartridges and activation mechanisms. According to some embodiments, the activation mechanism requires lower manual activation force by using the pressure in the cartridge to do part of the rupturing work. The cartridge can be filled with compressed gas such as nitrogen and argon, or supercritical fluids such as carbon dioxide, and can be used to propel or operate several types of devices and mechanisms including medical drug auto-injectors, paintball guns, tire emergency inflation kits, and inflatable life vests.
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公开(公告)号:US20180235840A1
公开(公告)日:2018-08-23
申请号:US15789478
申请日:2017-10-20
Applicant: AKTIVAX, INC.
Inventor: Amir Genosar
CPC classification number: A61J1/2093 , A61J1/067 , A61J1/201 , A61J1/2024 , A61J1/2096 , A61M5/2448 , A61M5/2455 , A61M5/28 , A61M5/284 , A61M5/285 , B65D75/367 , B65D75/368 , B65D2221/00
Abstract: A cartridge for use with a beneficial agent delivery device having a fillable reservoir. The cartridge includes a reconstitution, unit dose package having first and second compartments, and a fitment. The first compartment contains at least a first constintuent of the beneficial agent. The second compartment contains at least a second constituent of the beneficial agent. The fitment is disposed on the package for interfacing the package to the fillable reservoir.
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