公开(公告)号：US20230248643A1

公开(公告)日：2023-08-10

申请号：US18107421

申请日：2023-02-08

Applicant: AktiVax, Inc.

Inventor： Amir Genosar ,  Xicheng Sun ,  Melissa Varner

IPC: A61K9/00 ,  A61K31/197 ,  A61K47/10 ,  A61P7/04 ,  A61K47/02

CPC classification number: A61K9/0019 ,  A61K31/197 ,  A61K47/10 ,  A61P7/04 ,  A61K47/02

Abstract: Concentrated tranexamic acid compositions suitable for intramuscular administration via auto-injector are provided. Methods of treating non-compressible hemorrhage are also provided. Kits and auto-injectors comprising the tranexamic acid compositions are further provided.

公开(公告)号：US11185634B2

公开(公告)日：2021-11-30

申请号：US15792330

申请日：2017-10-24

Applicant: AktiVax, Inc.

Inventor： Amir Genosar

IPC: A61M5/24 ,  A61M5/19 ,  A61M5/28 ,  A61M5/315 ,  A61M5/50 ,  A61J1/20 ,  A61J1/06

Abstract: A dispensing device for use with a beneficial agent has a dispensing package, a dispenser disposed on an end portion of the dispensing package, and an actuator movably disposed along at least a portion of the package between a pre-dispensing state and a dispensing state. One arrangement also provides a beneficial agent dispenser having a dispensing port, an elongate portion and a plunger that is movably disposed relative to a tubular wall of the elongate portion during a dispensing stroke to partially penetrate a separable barrier and expel the beneficial agent through the dispensing port.

公开(公告)号：US20240335617A1

公开(公告)日：2024-10-10

申请号：US18293262

申请日：2022-07-28

Applicant: AKTIVAX, INC.

Inventor： Amir Genosar ,  Jason Fox

IPC: A61M5/315 ,  A61M5/20 ,  A61M5/32

CPC classification number: A61M5/31568 ,  A61M5/20 ,  A61M5/3202

Abstract: A beneficial agent dispensing device system is provided. The beneficial dispensing device system includes a dispensing device containing a beneficial agent, an indicium coupled to and selectively decouplable from the dispensing device, the indicium indicating information related to the beneficial agent, and a securing mechanism coupled to the indicium and configurable to secure the indicium to a securable feature.

公开(公告)号：US20230355881A1

公开(公告)日：2023-11-09

申请号：US18352458

申请日：2023-07-14

Applicant: Aktivax, Inc.

Inventor： Amir Genosar

IPC: A61M5/20 ,  A61M5/00 ,  A61M39/22 ,  A61M5/32

CPC classification number: A61M5/2066 ,  A61M5/008 ,  A61M5/2053 ,  A61M5/3234 ,  A61M39/22 ,  A61M2005/206 ,  A61M5/282

Abstract: An auto-injector operable to deliver a drug to a patient. The auto-injector may include a storage assembly with a first compartment and second compartment arranged to transition from an initial state in which the first compartment and the second compartment are separated to a merged state. The auto-injector may include a merging trigger configured for actuation responsive to manipulation and a merging mechanism comprising a compression element. Actuation of the merging trigger may cause movement of the merging mechanism such that the compression element compresses the first compartment.

公开(公告)号：US20210292073A1

公开(公告)日：2021-09-23

申请号：US17211448

申请日：2021-03-24

Applicant: Aktivax, Inc.

Inventor： Amir Genosar

IPC: B65D81/32 ,  B65D25/08

Abstract: A package comprising a container for holding a first sub-stance, and a product insert for holding a second substance, at least partially inserted info said container, and where the first product and the second product can be allowed to merge by external manipulation of said package. Packaged products and methods are also provided.

公开(公告)号：US20190151194A1

公开(公告)日：2019-05-23

申请号：US16014209

申请日：2018-06-21

Applicant: AKTIVAX, INC.

Inventor： Amir Genosar

IPC: A61J1/00 ,  A61J1/06 ,  B65D25/02 ,  A61J1/20

Abstract: A package for use with a beneficial agent delivery device. The package includes at least one filling chamber having a sealed penetrable access region, at least one compartment configured to hold a content, wherein the content includes at least one of a beneficial agent or a constituent of a beneficial agent, and at least one channel connecting the at least one filling chamber in fluid communication with the at least one compartment. At least a portion of the package is resealable to contain the content.

公开(公告)号：US20150136622A1

公开(公告)日：2015-05-21

申请号：US14290664

申请日：2014-05-29

Applicant: AktiVax, Inc.

Inventor： Amir Genosar

IPC: B65D81/32 ,  B65D25/08

CPC classification number: B65D81/32 ,  A61J1/201 ,  A61J1/2024 ,  A61J1/2027 ,  A61J1/2089 ,  A61J1/2093 ,  A61M5/2425 ,  A61M5/2448 ,  A61M5/2455 ,  A61M5/322 ,  A61M5/3234 ,  A61M2005/3224 ,  A61M2005/323 ,  B65D25/08 ,  B65D81/3205 ,  B65D81/3233 ,  B65D81/3266

Abstract: A package comprising a container for holding a first substance, and a product insert for holding a second substance, at least partially inserted info said container, and where the first product and the second product can be allowed to merge by external manipulation of said package. Packaged products and methods are also provided.

Abstract translation: 一种包括容纳第一物质的容器和用于保持第二物质的产品插入件，至少部分地插入所述容器，并且可以通过所述包装件的外部操作允许第一产品和第二产品合并。 还提供了包装的产品和方法。

公开(公告)号：US11844933B2

公开(公告)日：2023-12-19

申请号：US16933779

申请日：2020-07-20

Applicant: AKTIVAX, INC.

Inventor： Amir Genosar

IPC: A61M5/20 ,  A61M5/32 ,  A61M5/00 ,  A61M39/22 ,  A61M5/28 ,  A61M5/31

CPC classification number: A61M5/2066 ,  A61M5/008 ,  A61M5/2053 ,  A61M5/3234 ,  A61M39/22 ,  A61M5/282 ,  A61M2005/206 ,  A61M2005/2026 ,  A61M2005/3126 ,  A61M2209/088

Abstract: An auto-injector operable in a single activation step. The auto-injector is automatically armed when removed from its carrying receptacle. The auto-injector may be prefilled with more than one constituent of a beneficial agent, stored in separated compartments, in such an arrangement that the compartments will automatically merge when the auto-injector is removed from its carrying receptacle.

公开(公告)号：US11638794B2

公开(公告)日：2023-05-02

申请号：US16661824

申请日：2019-10-23

Applicant: AKTIVAX, INC.

Inventor： Amir Genosar

IPC: A61M15/08 ,  A61M15/00

Abstract: A beneficial agent dispensing device comprises a dispenser body comprising a pressure chamber and at least one dispensing port. A flexible primary container stores the beneficial agent contained within the body. The arrangement is such that pressure in the pressure chamber depress the flexible primary container to expel the beneficial agent through the dispensing port. The beneficial agent dispenser can be configured to deliver the beneficial agent intranasally.

公开(公告)号：US20220071844A1

公开(公告)日：2022-03-10

申请号：US17527710

申请日：2021-11-16

Applicant: Aktivax, Inc.

Inventor： Amir Genosar

IPC: A61J1/00 ,  A61J1/06 ,  A61J1/20 ,  B65D25/02

Abstract: A package for use with a beneficial agent delivery device. The package includes at least one filling chamber having a sealed penetrable access region, at least one compartment configured to hold a content, wherein the content includes at least one of a beneficial agent or a constituent of a beneficial agent, and at least one channel connecting the at least one filling chamber in fluid communication with the at least one compartment. At least a portion of the package is resealable to contain the content.