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11.发明公开公开(公告)号：US20240102038A1
公开(公告)日：2024-03-28
申请号：US18537046
申请日：2023-12-12
发明人： Dongmei XU , Jesse FREDERICK , Chengalrayan KUDITHIPUDI , Yanxin SHEN , James STRICKLAND , Jaemo YANG
IPC分类号： C12N15/82 , C07K14/415
CPC分类号： C12N15/8265 , C07K14/415 , C12N15/8213 , C12N15/8218 , C12N15/8225 , C12N15/8229 , C12N15/8261 , C12N15/8262 , C12N15/8294 , C12N2310/20
摘要： The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.
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公开(公告)号：US20240018536A1
公开(公告)日：2024-01-18
申请号：US18449849
申请日：2023-08-15
IPC分类号： C12N15/82 , C07K14/415 , C12P5/00
CPC分类号： C12N15/8262 , C12N15/8243 , C07K14/415 , C12N15/8223 , C12P5/007 , C12N2800/22
摘要： The present disclosure relates to compositions and methods related to tissue-specific promoters and their uses in plants, including tobacco and Cannabis. The provided trichome-specific promoters enable the expression of heterologous polynucleotides in trichome tissues.
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13.发明公开公开(公告)号：US20230348925A1
公开(公告)日：2023-11-02
申请号：US18182701
申请日：2023-03-13
IPC分类号： C12N15/82 , C12N9/04 , A24B15/24 , B01L3/00 , G01N1/38 , H02N11/00 , B01F33/45 , B01F33/452 , B01F33/501 , B01F35/75 , A01H4/00 , A24B13/00 , A24B15/10 , C07K14/415
CPC分类号： C12N15/8243 , C12N9/0006 , A24B15/245 , C12N15/825 , B01L3/502 , B01L3/50825 , G01N1/38 , H02N11/006 , B01F33/45 , B01F33/452 , B01F33/50112 , B01F35/754251 , A01H4/005 , A01H4/008 , A24B13/00 , A24B15/10 , C07K14/415 , C12N15/8205 , C12N15/8225 , B01L2200/0684 , B01L2300/043 , B01L2300/0672 , B01L2300/0867 , B01L2400/0403 , B01L2400/043 , B01L2400/0478 , B01L2400/0683 , G01N35/1079
摘要： The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
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公开(公告)号：US20220243216A1
公开(公告)日：2022-08-04
申请号：US17591057
申请日：2022-02-02
IPC分类号： C12N15/82
摘要： The present disclosure relates to compositions and methods related to modification of trichome density and transport of metabolite and their uses in plants, including tobacco and cannabis. The provided transcription factors enable the increase in trichome density in plants.
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公开(公告)号：US20220098604A1
公开(公告)日：2022-03-31
申请号：US17551565
申请日：2021-12-15
IPC分类号： C12N15/82 , C07K14/415
摘要： This disclosure provides a number of sequences involved in axillary bud growth in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences or transgenes of such sequences, and tobacco products made from tobacco leaf harvested from such plants.
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公开(公告)号：US20210275980A1
公开(公告)日：2021-09-09
申请号：US16838762
申请日：2020-04-02
摘要： The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
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公开(公告)号：US20240229054A9
公开(公告)日：2024-07-11
申请号：US18365270
申请日：2023-08-04
IPC分类号： C12N15/82 , A24B13/00 , A24B15/10 , C07K14/415
CPC分类号： C12N15/8243 , A24B13/00 , A24B15/10 , C07K14/415
摘要： The present disclosure relates to tobacco plants, plant parts, seeds, compositions, and methods related to modulating the expression of novel genes in tobacco to regulate alkaloid levels.
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18.发明公开公开(公告)号：US20240218386A1
公开(公告)日：2024-07-04
申请号：US17781797
申请日：2020-12-02
CPC分类号： C12N15/8243 , A24B13/00 , A24B15/00
摘要： The present disclosure provides composition and methods for manipulating alkaloid or nicotine levels in tobacco plants. Also provided are the identification and genetic engineering of target genes (e.g., arginine decarboxylase (ADC), aspartate oxidase (AO), or ornithine decarboxylase (ODC)) for producing tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.
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公开(公告)号：US20220403402A1
公开(公告)日：2022-12-22
申请号：US17830072
申请日：2022-06-01
摘要： The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), increase phenylalanine, or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.
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公开(公告)号：US20220243215A1
公开(公告)日：2022-08-04
申请号：US17591033
申请日：2022-02-02
IPC分类号： C12N15/82 , C07K14/415 , C12P5/00
摘要： Composition and methods for the modification of the secondary metabolic functions of glandular trichomes in plants, such as tobacco or Cannabis, that control the formation of terpenes that impart specific flavor and aroma characteristics to the plant leaves are provided. Enhanced terpene production and composition are achieved through targeted modification in the biochemical synthesis pathways for menthol and cis-abienol. This application provides novel nucleotide sequences encoding the enzymology for production of these terpenes in tobacco and Cannabis application to their use plants.
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