-
公开(公告)号：US09931055B2
公开(公告)日：2018-04-03
申请号：US14431730
申请日：2013-09-27
Inventor： Erica Forzani , Nongjian Tao , Xiaojun Xian , Francis Tsow
IPC: A61B5/08 , A61B5/097 , A61B5/087 , G01N33/497
CPC classification number: A61B5/082 , A61B5/087 , A61B5/097 , G01N33/497
Abstract: A low back pressure mouthpiece for accurate detection of exhaled nitric oxide (NO) includes a conduit for receiving the exhaled breath from the subject. An oxidizing filter for sample conditioning, wherein the conduit and oxidizing filter operate to produce a back pressure of less than 4 cm H2O; and a device for measuring the level of one or more components of the received exhaled breath.
-
12.发明公开公开(公告)号：US20240052395A1
公开(公告)日：2024-02-15
申请号：US18494225
申请日：2023-10-25
Inventor： Nongjian Tao , Shaopeng Wang , Hui Yu
CPC classification number: C12Q1/18 , G16H10/40 , G16H50/20 , G16H30/40 , G01N21/51 , G06T7/0012 , G01N2201/1296 , G06T2207/10016 , G06T2207/10056 , G06T2207/20081 , G06T2207/20084 , G06T2207/30024
Abstract: A method for deep learning video microscopy-based antimicrobial susceptibility testing of a bacterial strain in a sample by acquiring image sequences of individual bacterial cells of the bacterial strain in a subject sample before, during, and after exposure to each antibiotic at different concentrations. The image sequences are compressed into static images while preserving essential phenotypic features. Data representing the static images are input into a pre-trained deep learning (DL) model which generates output data; and antimicrobial susceptibility for the bacterial strain is determined from the output data.
-
公开(公告)号：US11559807B2
公开(公告)日：2023-01-24
申请号：US16689530
申请日：2019-11-20
Inventor： Nongjian Tao , Wenwen Jing
IPC: G01N33/543 , B01L3/00 , G01N1/38
Abstract: A method for detecting biomarkers with shortened test time and maximized precision. A sample from the body fluid is made to flow over a sensor surface coated with a capture antibody to allow binding of a biomarker in the sample to the capture body. An optical method detects and counts the individual binding events along the sensor surface with single molecule resolution, and difference in the binding events along the sensor surface is detected in real time and analyzed to determine the biomarker concentration.
-
14.发明申请公开(公告)号：US20210054432A1
公开(公告)日：2021-02-25
申请号：US17072742
申请日：2020-10-16
Inventor： Nongjian Tao , Karan Syal
IPC: C12Q1/18 , G01N15/14 , G01N33/543 , G06K9/00
Abstract: A method for rapid antibiotic susceptibility testing by tracking sub-micron scale motion of single bacterial cells including obtaining a biological sample from a subject including live bacteria. Different doses of antibiotic are added to a multi-well glass slide and adding portions of the biological sample to the wells. Bacterial cells are tethered onto the surface. The tethered bacterial cells are imaged and tracked. Bacterial sub-micron motion of tethered cells is measured at the different doses. A processor performs statistical analysis on a population of cells for each antibiotic dose to generate an antibiotic dose curve proportional to the motion changes, where the antibiotic dose curve plots data including a decrease in movement over time indicating a proportional effectiveness of an antibiotic applied to a well.
-
15.发明申请公开(公告)号：US20190257802A1
公开(公告)日：2019-08-22
申请号：US16279698
申请日：2019-02-19
Inventor： Erica Forzani , Nongjian Tao , Di Zhao , Francis Tsow
IPC: G01N33/00 , A61B5/00 , G01N21/84 , A61B5/08 , G01N33/497
Abstract: A method for CO2 detection includes obtaining a gas sample; exposing a CO2 sensor to the gas sample, where the sensor includes a reversible and selective pH-sensitive nanocomposite sensor element for CO2 detection, and a hydrophobic surface; compensating for humidity and temperature; coupling at least one light source to receive signals from the CO2 sensor and respond to color changes in the sensor by transducing the color change into a light intensity change; measuring flow; and receiving signals from the at least one light source by at least one photodiode which responds to light intensity changes by transducing the light intensity changes into electronic signals representing varying degrees of light intensity.
-
Patent Agency Ranking
16.发明申请公开(公告)号：US20190082972A1
公开(公告)日：2019-03-21
申请号：US16083052
申请日：2017-03-08
Inventor： Nongjian Tao , Dangdang Shao
IPC: A61B5/0205 , A61B5/00 , A61B5/11 , A61B5/021 , G06T7/20
Abstract: Various embodiments of systems and methods for tracking ballistocardiogram, photoplethysmogram, blood pressure and abnormal heart rhythm based on optical imaging of a human body are disclosed. Ballistocardiogram and photoplethysmogram signals from a similar region of the human body are simultaneously obtained, and the time delay between the two signals is used to determine the blood pressure of the subject, together with other physiological parameters of the subject, including gender, age, weight, height, heart rate, stroke volume, blood pressure and abnormal heart rhythm obtained using other methods.
-
公开(公告)号：US20180140255A1
公开(公告)日：2018-05-24
申请号：US15826224
申请日：2017-11-29
Inventor： Nongjian Tao , Dangdang Shao
CPC classification number: A61B5/7239 , A61B5/004 , A61B5/0077 , A61B5/024 , A61B5/0816 , A61B5/087 , A61B5/1128 , A61B5/113
Abstract: A system and method for monitoring one or more physiological parameters of a subject under free-living conditions is provided. The system includes a camera configured to capture and record a video sequence including at least one image frame of at least one region of interest (ROI) of the subject's body. A computer in signal communication with the camera to receive signals transmitted by the camera representative of the video sequence includes a processor configured to process the signals associated with the video sequence recorded by the camera and a display configured to display data associated with the signals.
-
公开(公告)号：US20160299069A1
公开(公告)日：2016-10-13
申请号：US15038629
申请日：2015-01-02
Inventor： Nongjian Tao , Hui Yu , Xiaonan Shan , Shaopeng Wang
IPC: G01N21/552
CPC classification number: G01N21/553 , C12M41/46 , G01N21/552
Abstract: Method and system to remove background noise with a differential approach in optical imaging is disclosed. The differential approach moves the sample position laterally over a small distance, and a differential image is generated from the images recorded before and after the lateral translation. This approach can significantly improve the image quality of objects, including single DNA molecules, for label-free optical imaging techniques, such as surface plasmon resonance imaging. Disclosed imaging technique provides high-resolution genome-wide restriction maps of single DNA molecules.
Abstract translation: 公开了在光学成像中用差分方法去除背景噪声的方法和系统。 差分方法将样本位置横向移动一小段距离，并且从侧向平移之前和之后记录的图像产生差分图像。 这种方法可以显着提高物体（包括单个DNA分子）的图像质量，用于无标记光学成像技术，如表面等离子体共振成像。 公开的成像技术提供了单分子DNA分子的高分辨率全基因组限制性图谱。
-
公开(公告)号：US11834696B2
公开(公告)日：2023-12-05
申请号：US16500370
申请日：2018-04-05
Inventor： Nongjian Tao , Shaopeng Wang , Hui Yu
CPC classification number: C12Q1/18 , G01N21/51 , G06T7/0012 , G16H10/40 , G16H30/40 , G16H50/20 , G01N2201/1296 , G06T2207/10016 , G06T2207/10056 , G06T2207/20081 , G06T2207/20084 , G06T2207/30024
Abstract: A method for deep learning video microscopy-based antimicrobial susceptibility testing of a bacterial strain in a sample by acquiring image sequences of individual bacterial cells of the bacterial strain in a subject sample before, during, and after exposure to each antibiotic at different concentrations. The image sequences are compressed into static images while preserving essential phenotypic features. Data representing the static images is input into a pre-trained deep learning (DL) model which generates output data; and antimicrobial susceptibility for the bacterial strain is determined from the output data.
-
公开(公告)号：US20230113468A1
公开(公告)日：2023-04-13
申请号：US18072459
申请日：2022-11-30
Inventor： Nongjian Tao , Wenwen Jing
IPC: B01L3/00 , G01N1/38 , G01N33/543
Abstract: A method for detecting biomarkers with shortened test time and enhanced precision is provided. A sample from the body fluid is made to flow over a sensor surface coated with a capture antibody to allow binding of a biomarker in the sample to the capture body. An optical method detects and counts the individual binding events along the sensor surface with single molecule resolution, and difference in the binding events along the sensor surface is detected in real-time and analyzed to determine the biomarker concentration.
-
-
-
-
-
-
-
-
-
Search Results
33
records
(took 0.028 seconds)
