公开(公告)号：US20180057482A1

公开(公告)日：2018-03-01

申请号：US15804485

申请日：2017-11-06

Applicant: AbbVie Inc.

Inventor： Russell D. Cink ,  Kirill A. Lukin ,  Marvin R. Leanna ,  Matthew J. Pelc ,  Timothy B. Towne ,  Dennie S. Welch ,  Kenneth M. Engstrom ,  Matthew M. Ravn ,  Richard D. Bishop ,  Gang Zhao ,  Jianzhang Mei ,  Jeff M. Kallemeyn ,  David R. Hill ,  Michael J. Abrahamson ,  Westin H. Morrill

IPC: C07D403/12 ,  C07C67/08 ,  C07C41/26 ,  C07C269/04 ,  C07C269/06 ,  C07D487/04 ,  C07C69/74 ,  C07C271/34 ,  C07D405/06 ,  C07D241/44 ,  C07D405/14 ,  C07C43/196

CPC classification number: C07D403/12 ,  C07C41/26 ,  C07C43/196 ,  C07C67/08 ,  C07C68/02 ,  C07C69/74 ,  C07C211/35 ,  C07C269/04 ,  C07C269/06 ,  C07C271/34 ,  C07C2601/08 ,  C07D241/44 ,  C07D405/06 ,  C07D405/14 ,  C07D487/04 ,  C12P1/00 ,  C07C69/96 ,  C07C69/14

Abstract: The invention provides methods of synthesizing a viral protease inhibitor in high yield, without using expensive catalysts or challenging reaction conditions.