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公开(公告)号:US20160030212A1
公开(公告)日:2016-02-04
申请号:US14880905
申请日:2015-10-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: John Stankus , Yunbing Wang , Mikael Trollsas , Syed Faiyaz Ahmed Hossainy , Michael H. Ngo , Dariush Davalian
IPC: A61F2/915
CPC classification number: A61F2/915 , A61F2210/0004 , A61F2210/0057 , A61F2230/0013 , A61F2230/0054 , A61L31/041 , A61L31/129 , A61L31/141 , A61L31/148
Abstract: Bioabsorbable scaffolds are disclosed with a rigid polymer component and a rubbery polymer component. The rubbery polymer component is miscible, partially miscible, or immiscible with the rigid polymer component.
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公开(公告)号:US20150150989A1
公开(公告)日:2015-06-04
申请号:US14621301
申请日:2015-02-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Stephen Dirk Pacetti , Yiwen Tang , Syed Faiyaz Ahmed Hossainy
IPC: A61K47/34 , C09D167/00 , C08K5/1575 , A61K31/436
CPC classification number: A61K47/34 , A61K31/436 , A61L27/34 , A61L27/502 , A61L31/10 , A61L31/141 , C08K5/1575 , C08L67/04 , C09D167/00
Abstract: A biocompatible plasticizer useful for forming a coating composition with a biocompatible polymer is provided. The coating composition may also include a biobeneficial polymer and/or a bioactive agent. The coating composition can form a coating on an implantable device. The implantable device can be used to treat or prevent a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof
Abstract translation: 提供了可用于形成具有生物相容性聚合物的涂料组合物的生物相容性增塑剂。 涂料组合物还可以包括生物有益的聚合物和/或生物活性剂。 涂料组合物可以在可植入装置上形成涂层。 可植入装置可用于治疗或预防动脉粥样硬化,血栓形成,再狭窄,出血,血管解剖或穿孔,血管动脉瘤,易损斑块,慢性完全闭塞,跛行,静脉和人造移植物的吻合增殖等障碍,胆管阻塞 ,输尿管阻塞,肿瘤阻塞或其组合
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公开(公告)号:US20150081000A1
公开(公告)日:2015-03-19
申请号:US14484943
申请日:2014-09-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Syed Faiyaz Ahmed Hossainy , John E. Papp , Joel Harrington
CPC classification number: A61L31/148 , A61F2/88 , A61F2/90 , A61F2/966 , A61F2002/826 , A61F2002/9517 , A61F2250/0018 , A61F2250/0031 , A61F2250/0039 , A61F2250/0067 , A61L31/128 , C08L67/04
Abstract: A braided polymeric scaffold, made at least in part from a bioresorbable material is deployed on a catheter that uses a push-pull mechanism to deploy the scaffold. A drug coating is disposed on the scaffold. A plurality of scaffold segments on a catheter is also disclosed.
Abstract translation: 至少部分由生物可吸收材料制成的编织聚合物支架部署在使用推拉机构部署支架的导管上。 药物涂层设置在支架上。 还公开了导管上的多个支架段。
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公开(公告)号:US20140294912A1
公开(公告)日:2014-10-02
申请号:US14307316
申请日:2014-06-17
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Stephen D. Pacetti , Syed Faiyaz Ahmed Hossainy , David C. Gale
CPC classification number: A61L31/10 , A61L31/06 , A61L31/148 , A61L31/16 , C08L101/00 , C09D167/04 , C08L67/04 , C08L2666/02
Abstract: Implantable devices formed of or coated with a material that includes an amorphous poly(D,L-lactide) formed of a starting material such as meso-D,L-lactide are provided. The implantable device can be used for the treatment, mitigation, prevention, or inhibition of a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.
Abstract translation: 提供由包含由诸如内消旋-D,L-丙交酯的原料形成的无定形聚(D,L-丙交酯)的材料形成或涂覆的可植入装置。 可植入装置可用于治疗,缓解,预防或抑制动脉粥样硬化,血栓形成,再狭窄,出血,血管解剖或穿孔,血管动脉瘤,易损斑块,慢性完全闭塞,卵圆孔未闭,跛行, 静脉和人造移植物的吻合增殖,胆管阻塞,输尿管阻塞,肿瘤阻塞或其组合。
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公开(公告)号:US20140228930A1
公开(公告)日:2014-08-14
申请号:US14254812
申请日:2014-04-16
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor: John E. Papp , Mikael Trollsas , Dariush Davalian , Yunbing Wang , Syed Faiyaz Ahmed Hossainy
IPC: A61F2/89
CPC classification number: A61F2/89 , A61F2/915 , A61F2002/825 , A61F2002/828 , A61F2002/91558 , A61F2002/91575 , A61F2220/005 , A61F2230/0013 , A61F2230/0054
Abstract: Stent scaffolds that include a polymeric structure or structures bonded to the scaffold and extending along their length are disclosed. The polymeric structure extends across some or all of the gaps in struts along the length of the scaffold. Segmented scaffolds are also disclosed that include two or more axial segments arranged end to end not connected by link sruts.
Abstract translation: 公开了包括结合到支架上并沿其长度延伸的聚合物结构或结构的支架。 聚合物结构沿着支架的长度延伸穿过支柱中的一些或全部间隙。 还公开了分段支架,其包括端对端布置的两个或更多个轴向段,其不被连接部分连接。
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公开(公告)号:US20140079742A1
公开(公告)日:2014-03-20
申请号:US14081929
申请日:2013-11-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Mikael O. Trollsas , Michael Huy Ngo , Bozena Zofia Maslanka , Syed Faiyaz Ahmed Hossainy , Lothar W. Kleiner
IPC: C09D143/02
CPC classification number: A61L31/10 , A61F2/82 , A61L27/34 , A61L27/54 , A61L27/58 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/606 , C09D143/02
Abstract: A coating of fast absorption or fast dissolution on an implantable device and methods of making and using of the coating are provided.
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公开(公告)号:US08591934B2
公开(公告)日:2013-11-26
申请号:US13677115
申请日:2012-11-14
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Syed Faiyaz Ahmed Hossainy , Thierry Glauser , Mikael O. Trollsas
IPC: A61F2/00
CPC classification number: A61K47/32 , A61F2/82 , A61K45/06 , A61K47/65 , A61K47/6957 , A61L31/10 , A61L31/16 , A61L2300/00 , C08L33/26
Abstract: An implantable device including a conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided.
Abstract translation: 提供了包括由丙烯酰胺类共聚物和生物活性剂形成的共轭物的可植入装置。
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公开(公告)号:US10004834B2
公开(公告)日:2018-06-26
申请号:US14484943
申请日:2014-09-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Syed Faiyaz Ahmed Hossainy , John E. Papp , Joel Harrington
CPC classification number: A61L31/148 , A61F2/88 , A61F2/90 , A61F2/966 , A61F2002/826 , A61F2002/9517 , A61F2250/0018 , A61F2250/0031 , A61F2250/0039 , A61F2250/0067 , A61L31/128 , C08L67/04
Abstract: A braided polymeric scaffold, made at least in part from a bioresorbable material is deployed on a catheter that uses a push-pull mechanism to deploy the scaffold. A drug coating is disposed on the scaffold. A plurality of scaffold segments on a catheter is also disclosed.
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公开(公告)号:US09302030B2
公开(公告)日:2016-04-05
申请号:US14476597
申请日:2014-09-03
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Syed Faiyaz Ahmed Hossainy , Mikael Trollsas , Lothar Walter Kleiner
IPC: A61L31/10 , A61L31/16 , C08F114/28 , C08F214/28 , C08F114/22 , C08F214/22
CPC classification number: A61L31/16 , A61L31/10 , A61L2300/416 , A61L2420/02 , A61L2420/04 , B05D3/14 , C08F14/22 , C08F114/22 , C08F214/22 , C08F214/28
Abstract: Provided herein is a prohealing piezoelectric coating and the method of making and using the same.
Abstract translation: 本文提供了一种预热压电涂层及其制造和使用方法。
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公开(公告)号:US20150328375A1
公开(公告)日:2015-11-19
申请号:US14664554
申请日:2015-03-20
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Thierry Glauser , Stephen Dirk Pacetti , Syed Faiyaz Ahmed Hossainy , Ni Ding
CPC classification number: A61L31/10 , A61L27/34 , A61L31/148 , A61L31/16 , A61L33/0011 , A61L33/08 , A61L2300/40 , A61L2300/42 , A61L2300/604 , A61L2300/606 , A61L2400/18 , C08L33/14
Abstract: A polymer comprising phospholipid moieties and a biocompatible polymer backbone, a composition comprising the polymer and optionally a bioactive agent, an implantable devices such as a DES comprising thereon a coating comprising the polymer and optionally a bioactive agent, and a method of using the device for the treatment of a disorder in a human being are provided.
Abstract translation: 包含磷脂部分和生物相容性聚合物骨架的聚合物,包含聚合物和任选的生物活性剂的组合物,可植入装置,例如包含其上的包含聚合物和任选的生物活性剂的涂层的DES,以及使用该装置的方法 提供了人类疾病的治疗。
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