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    Drug delivery system with temperature-sensitive control
    12.
    发明授权
    Drug delivery system with temperature-sensitive control 有权

    公开(公告)号：US11383047B2

    公开(公告)日：2022-07-12

    申请号：US16589037

    申请日：2019-09-30

    Applicant: AMGEN INC.

    Inventor： Scott R. Gibson ,  Mark Ka Lai Lee ,  Donald Busby ,  Stephanie Toy ,  Suhas Krishna ,  Francisca Tan-Malecki ,  Ferry Tamtoro

    IPC: A61M5/44 ,  A61M5/315 ,  A61M5/20 ,  A61M5/142 ,  A61M5/162 ,  A61M5/172 ,  A61M5/31

    Abstract: A drug delivery system includes a reservoir and a drug delivery device coupled to the reservoir. The drug delivery device also may include at least one temperature-sensitive component and a lock having locked and unlocked states. The system further includes an output device, and a controller coupled to the lock and the output device. The controller may also include a temperature sensor, or may be coupled to the temperature sensor. The controller is programmed or configured to determine if the temperature of a drug in the reservoir or of the temperature-sensitive component exceeds an upper limit or is below a lower limit, and to activate the lock in either event. The controller is also programmed or configured to determine, directly or indirectly, if the temperature subsequently is between the upper and lower limits, and to unlock lock as a consequence.

    Drug cassette, autoinjector, and autoinjector system
    13.
    发明授权
    Drug cassette, autoinjector, and autoinjector system 有权

    公开(公告)号：US11020537B2

    公开(公告)日：2021-06-01

    申请号：US15782925

    申请日：2017-10-13

    Applicant: AMGEN INC.

    Inventor： R. Paul Mounce ,  Clinton Judd ,  Suhas Krishna ,  Neal Johnston ,  Gordon Johnston ,  Giorgio Sardo ,  Gabriele Ganzitti ,  Hong Jun Yeh

    IPC: A61M5/32 ,  A61M5/24 ,  A61M5/20 ,  A61M5/48 ,  A61J1/18 ,  A61M5/42 ,  A61M5/46 ,  G09B23/28

    Abstract: A cassette for use with an injector has a housing, and a cassette identification arrangement (cassette ID) defining a code containing information about the cassette that is detectable and decipherable by an injector. The cassette may further have a sleeve movably disposed within the housing, for holding a drug container, and a locking arrangement for interlocking the sleeve with the housing. The cassette may further have an aperture in the housing, and a cassette cap for removing a needle shield of the drug container. The cassette may have an anti-bending structure to prevent bending or flexing of the cassette cap. The injector may have a processor for controlling operational parameters of the injector and a detector communicatively coupled with the processor for detesting and communicating the cassette ID to the microprocessor to decipher the code defined therein. Also, a method of injecting a drug into a patient with an injector, wherein the sequence of actions performed by the user are controlled. Still further, a method of treating a patient in need thereof wherein a cassette containing a drug is provided and administered to the patient using an injector.

    Drug cassette, autoinjector, and autoinjector system
    14.
    发明授权
    Drug cassette, autoinjector, and autoinjector system 有权

    公开(公告)号：US10786629B2

    公开(公告)日：2020-09-29

    申请号：US15782951

    申请日：2017-10-13

    Applicant: AMGEN INC.

    Inventor： R. Paul Mounce ,  Clinton Judd ,  Suhas Krishna ,  Neal Johnston ,  Gordon Johnston ,  Giorgio Sardo ,  Gabriele Ganzitti ,  Hong Jun Yeh

    IPC: A61M5/32 ,  A61M5/24 ,  A61M5/20 ,  A61M5/42 ,  A61M5/46 ,  A61M5/48 ,  G09B23/28 ,  A61J1/18

    Abstract: A cassette for use with an injector has a housing, and a cassette identification arrangement (cassette ID) defining a code containing information about the cassette that is detectable and decipherable by an injector. The cassette may further have a sleeve movably disposed within the housing, for holding a drug container, and a locking arrangement for interlocking the sleeve with the housing. The cassette may further have an aperture in the housing, and a cassette cap for removing a needle shield of the drug container. The cassette may have an anti-bending structure to prevent bending or flexing of the cassette cap. The injector may have a processor for controlling operational parameters of the injector and a detector communicatively coupled with the processor for detecting and communicating the cassette ID to the microprocessor to decipher the code defined therein. Also, a method of injecting a drug into a patient with an injector, wherein the sequence of actions performed by the user are controlled. Still further, a method of treating a patient in need thereof wherein a cassette containing a drug is provided and administered to the patient using an injector.

    Drug delivery system with temperature-sensitive control
    15.
    发明授权
    Drug delivery system with temperature-sensitive control 有权

    公开(公告)号：US10758683B2

    公开(公告)日：2020-09-01

    申请号：US14913928

    申请日：2014-10-22

    Applicant: AMGEN INC.

    Inventor： Scott R. Gibson ,  Mark Ka Lai Lee ,  Donald Busby ,  Stephanie Toy ,  Suhas Krishna ,  Francisca Tan-Malecki ,  Ferry Tamtoro

    IPC: A61M5/44 ,  A61M5/162 ,  A61M5/315 ,  A61M5/20 ,  A61M5/142 ,  A61M5/172 ,  A61M5/31

    Abstract: A drug delivery system includes a reservoir and a drug delivery device coupled to the reservoir. The drug delivery device also may include at least one temperature-sensitive component and a lock having locked and unlocked states. The system further includes an output device, and a controller coupled to the lock and the output device. The controller may also include a temperature sensor, or may be coupled to the temperature sensor. The controller is programmed or configured to determine if the temperature of a drug in the reservoir or of the temperature-sensitive component exceeds an upper limit or is below a lower limit, and to activate the lock in either event. The controller is also programmed or configured to determine, directly or indirectly, if the temperature subsequently is between the upper and lower limits, and to unlock lock as a consequence.

    DRUG CASSETTE, AUTOINJECTOR, AND AUTOINJECTOR SYSTEM
    18.
    发明申请
    DRUG CASSETTE, AUTOINJECTOR, AND AUTOINJECTOR SYSTEM 审中-公开

    公开(公告)号：US20180098914A1

    公开(公告)日：2018-04-12

    申请号：US15782951

    申请日：2017-10-13

    Applicant: AMGEN INC.

    Inventor： R. Paul Mounce ,  Clinton Judd ,  Suhas Krishna ,  Neal Johnston ,  Gordon Johnston ,  Giorgio Sardo ,  Gabriele Ganzitti ,  Hong Jun Yeh

    IPC: A61J1/18 ,  A61M5/20 ,  A61M5/24 ,  A61M5/32 ,  A61M5/48 ,  A61M5/46 ,  A61M5/42 ,  G09B23/28

    Abstract: A cassette for use with an injector has a housing, and a cassette identification arrangement (cassette ID) defining a code containing information about the cassette that is detectable and decipherable by an injector. The cassette may further have a sleeve movably disposed within the housing, for holding a drug container, and a locking arrangement for interlocking the sleeve with the housing. The cassette may further have an aperture in the housing, and a cassette cap for removing a needle shield of the drug container. The cassette may have an anti-bending structure to prevent bending or flexing of the cassette cap. The injector may have a processor for controlling operational parameters of the injector and a detector communicatively coupled with the processor for detecting and communicating the cassette ID to the microprocessor to decipher the code defined therein. Also, a method of injecting a drug into a patient with an injector, wherein the sequence of actions performed by the user are controlled. Still further, a method of treating a patient in need thereof wherein a cassette containing a drug is provided and administered to the patient using an injector.

    Drug Delivery System With Temperature-Sensitive Control
    19.
    发明申请
    Drug Delivery System With Temperature-Sensitive Control 审中-公开
    具有温度敏感控制的药物输送系统

    公开(公告)号：US20160354555A1

    公开(公告)日：2016-12-08

    申请号：US14913928

    申请日：2014-10-22

    Applicant: AMGEN INC.

    Inventor： Scott R. Gibson ,  Lee Foster ,  Donald Busby ,  Stephanie Toy ,  Suhas Krishna ,  Francisca Tan-Malecki ,  Ferry Tamtoro

    IPC: A61M5/44 ,  A61M5/31 ,  A61M5/172 ,  A61M5/142 ,  A61M5/162

    Abstract: A drug delivery system includes a reservoir and a drug delivery device coupled to the reservoir. The drug delivery device also may include at least one temperature-sensitive component and a lock having locked and unlocked states. The system further includes an output device, and a controller coupled to the lock and the output device. The controller may also include a temperature sensor, or may be coupled to the temperature sensor. The controller is programmed or configured to determine if the temperature of a drug in the reservoir or of the temperature-sensitive component exceeds an upper limit or is below a lower limit, and to activate the lock in either event. The controller is also programmed or configured to determine, directly or indirectly, if the temperature subsequently is between the upper and lower limits, and to unlock lock as a consequence.

    Abstract translation: 药物递送系统包括联接到储存器的储存器和药物输送装置。 药物递送装置还可以包括至少一个温度敏感组件和具有锁定和解锁状态的锁。 该系统还包括输出装置和耦合到锁和输出装置的控制器。 控制器还可以包括温度传感器，或者可以耦合到温度传感器。 控制器被编程或配置为确定储存器或温度敏感组件中的药物的温度是否超过上限或低于下限，并且在任一情况下激活锁定。 控制器也被编程或配置为直接或间接地确定温度是否在上限和下限之间，并因此解锁锁定。

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