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11.发明授权公开(公告)号：US09829366B2
公开(公告)日：2017-11-28
申请号：US14517460
申请日：2014-10-17
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： Ye Chen , Yuanpang Samuel Ding , Matthew Muller , Gert Najdeni , Joel Titus
IPC: G01F23/26 , G01F23/284 , A61M1/16 , G01F22/00 , A61M1/28
CPC classification number: A61M5/1684 , A61M1/14 , A61M1/16 , A61M1/1605 , A61M1/1607 , A61M1/1668 , A61M1/28 , A61M1/287 , A61M5/14 , A61M5/1407 , A61M5/1409 , A61M5/142 , A61M2205/3317 , A61M2205/3379 , A61M2205/3389 , A61M2205/52 , G01F22/00 , G01F23/26 , G01F23/263 , G01F23/284
Abstract: A medical fluid system includes a container holding a fluid at a level; and a radio frequency level sensor operably connected to the container and including an emitting electrode and a receiving electrode, the electrodes operating as a transmission line having an electrical impedance that varies with the level or volume of the fluid in the container, the level sensor configured to measure a phase shift of the transmission line, the phase shift indicative of the level or volume of the fluid in the container.
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公开(公告)号：US20170189594A1
公开(公告)日：2017-07-06
申请号：US15074388
申请日：2016-03-18
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： Yuanpang Samuel Ding , Cristian Adolfo Menzel Bueno , Rosa Yeh
CPC classification number: A61M1/169 , A61M1/1672 , A61M1/1696 , B01D61/422 , B01D61/445 , B01D61/46 , C02F1/4693 , C02F2101/16 , C25B3/02 , C25B9/06
Abstract: The present disclosure provides devices and methods of using same for cleansing a solution (e.g., a salt solution) of urea via electrooxidation, and more specifically to cleansing a renal therapy solution/dialysis solution of urea via electrooxidation so that the renal therapy solution/dialysis solution can be used or reused for treatment of a patient. In an embodiment, a device for the removal of urea from a fluid having urea to produce a cleansed fluid includes a urea decomposition unit and an electrodialysis unit.
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公开(公告)号：US12220508B2
公开(公告)日：2025-02-11
申请号：US17486390
申请日：2021-09-27
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： Cristian Adolfo Menzel Bueno , Yuanpang Samuel Ding , Rosa Yeh
Abstract: A urea separation apparatus is described herein. In an embodiment, the urea separation apparatus includes a blood compartment that is a part of an extracorporeal circuit fluidly connected to a patient and configured to receive blood of the patient. The apparatus also includes a waste membrane enclosing the blood compartment that is configured to filter waste from the blood. The apparatus further includes a dialysis fluid compartment located on an opposite side of the waste membrane from the blood compartment. The dialysis fluid compartment includes dialysis fluid that absorbs the waste from the waste membrane. The apparatus moreover includes a charged membrane enclosing the dialysis fluid compartment. The charged membrane is configured to filter at least a portion of the waste from the dialysis fluid. Additionally, the apparatus includes a urea compartment that circulates secondary fluid for absorbing the portion of the waste from the charged membrane.
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14.发明授权公开(公告)号：US11724012B2
公开(公告)日：2023-08-15
申请号：US17493132
申请日：2021-10-04
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： Jeff White , Ye Chen , Yuanpang Samuel Ding , Joel Titus , Justin Rohde , Shincy Maliekkal , Kevin Cooper
IPC: G01N27/416 , G01N33/00 , G01N27/30 , G01N27/413 , A61M1/16 , C02F1/50 , C02F103/02
CPC classification number: A61M1/1656 , A61M1/1603 , A61M1/1664 , A61M1/1668 , C02F1/50 , G01N27/30 , G01N27/413 , G01N27/4168 , G01N33/0036 , A61M2205/3327 , A61M2205/502 , A61M2205/75 , C02F2103/026 , Y02W10/33
Abstract: A dialysis method and system for determining an amount of total chlorine in a partially purified water sample is disclosed. The system includes a water machine that produces at least partially purified water including an at least partially purified water sample and a dialysis machine that provides a dialysis treatment to a patient. The dialysis machine receives the at least partially purified water from the water machine to prepare dialysis fluid for the dialysis treatment. The system also includes a total chlorine detector configured to receive the at least partially purified water sample, at a first time apply a source voltage to the at least partially purified water sample, and at a second time stop applying the source voltage to the at least partially purified water sample and instead monitor a sensed electrical parameter to determine an amount of total chlorine in the at least partially purified water sample.
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公开(公告)号：US11623773B2
公开(公告)日：2023-04-11
申请号：US17327527
申请日：2021-05-21
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： Grant Anthony Bomgaars , Joseph Vincent Ranalletta , Yuanpang Samuel Ding , Ying-Cheng Lo , Mark Edward Pasmore , Michael Joseph Sadowski , Anastasios Hristakos , Thomas Edward Dudar , Bernd Krause
Abstract: A method of providing a plurality of filled product bags of sterile fluid includes positioning a bag assembly onto a filling machine. The bag assembly includes a tube, a filter assembly, bladders, and stems. A stem is attached to a bladder, forms a fluid passageway, fluidly connects to the tube, and provides fluid communication into the bladders. The method includes fluidly coupling an inlet of the filter assembly to a connection line in fluid communication with a fluid source, and filling the bag assembly with a fluid. Filling the bag assembly includes passing the fluid through the filter assembly, the fluid passageway, and into the bladder. The method includes sealing the fluid passageway at a location between the tube and the bladders. The method includes cutting the stem to form a partially filled product bag having the sealed passageway. The method includes performing an integrity test on the filter assembly.
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Patent Agency Ranking
公开(公告)号：US11547797B2
公开(公告)日：2023-01-10
申请号：US16631051
申请日：2018-07-12
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： Yuanpang Samuel Ding , Marc Steven Minkus , Ying-Cheng Lo , Mark Joseph Doty , Thomas Edward Dudar , Grant Anthony Bomgaars , Mark Edward Pasmore , Michael Joseph Sadowski , Anastasios Hristakos , Bernd Krause , Joseph Vincent Ranalletta
Abstract: A syringe system includes a syringe and a filtration device connected to the syringe for sterilizing and introducing fluid into the syringe. The syringe includes a syringe barrel having a proximal end defining a barrel opening, a distal end defining a delivery opening, a bore extending between the proximal end and the distal end, and a stopper disposed in the bore of the syringe barrel. The filtration device has an inlet and an outlet coupled in fluid communication with the delivery opening at the distal end of the syringe barrel. The filtration device includes a stem and a filter membrane disposed in line with the stem. The filter membrane optionally has a plurality of pores each with a nominal pore size in a range of approximately 0.1 μm to approximately 0.5 μm such that a pharmaceutical fluid can be introduced as a sterilized pharmaceutical fluid into the bore of the syringe barrel by passing through the filtration device.
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公开(公告)号：US20220211579A1
公开(公告)日：2022-07-07
申请号：US17701125
申请日：2022-03-22
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： Yuanpang Samuel Ding , Ying-Cheng Lo , Jacob Daniel Rivett , Grant Anthony Bomgaars , Thomas Edward Dudar , Mark Edward Pasmore , Michael Joseph Sadowski , Anastasios Hristakos , Joseph Vincent Ranalletta , Bernd Krause
Abstract: A system for reconstituting and sterilizing a concentrate includes a mixing container, a filtration device, and a product bag. The a mixing container has an inlet port and outlet port in fluid communication with a mixing chamber disposed between the inlet port and the outlet port. The mixing chamber is adapted to contain a product concentrate. The filtration device has an inlet and an outlet, the inlet of the filtration device coupled to the outlet port of the mixing container. The filtration device includes a filter membrane with a nominal pore size in a range of approximately 0.1 μm to approximately 0.5 μm. The product bag has an inlet port coupled to the outlet of the filtration device, and has a bladder defining an empty sterile chamber for receiving sterilized and reconstituted product resulting from mixing a diluent with a product concentrate in the mixing chamber to obtain a mixture then introduced through the filtration device to obtain the reconstituted and sterilized product.
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公开(公告)号：US20200164128A1
公开(公告)日：2020-05-28
申请号：US16203104
申请日：2018-11-28
Applicant: Baxter International Inc. , Baxter Healthcare SA
Abstract: Methods, sorbent cartridges and cleaning devices are disclosed for refurbishing sorbent materials. In one implementation among multiple implementations, a medical fluid delivery method includes: providing a sorbent cartridge including H+ZP within a casing for a treatment; and after the treatment, refurbishing the H+ZP while maintained within the casing via (i) regenerating the non-disinfected H+ZP by flowing an acid solution through the casing, (ii) rinsing the regenerated H+ZP while maintained within the casing, (iii) disinfecting the regenerated and rinsed H+ZP by flowing a disinfecting agent through the casing, and (iv) rinsing the regenerated and disinfected H+ZP while maintained within the casing. Multiple batch sorbent refubishing implementations are also disclosed.
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公开(公告)号：US20200061270A1
公开(公告)日：2020-02-27
申请号：US16673451
申请日：2019-11-04
Applicant: Baxter International Inc. , Baxter Healthcare SA
Inventor： Cristian Adolfo Menzel Bueno , Yuanpang Samuel Ding , Rosa Yeh
Abstract: Methods and apparatuses for regenerating used dialysis fluid are described herein. In an embodiment, a regenerative dialysis fluid system includes a dialysis unit configured to generate used dialysis fluid including urea, a urea separation unit configured to separate at least a portion of the urea from the used dialysis fluid into a secondary fluid, and a urea removal unit configured to remove at least a portion of the urea from the secondary fluid and return the secondary fluid to the urea separation unit. In an embodiment, the urea separation unit includes a membrane separating a dialysis fluid chamber from a urea chamber, the membrane including at least one of: (i) a positive charge to prevent positive ions from transporting across the membrane; and (ii) a negative charge to prevent negative ions from transporting across the membrane.
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公开(公告)号：US20190388611A1
公开(公告)日：2019-12-26
申请号：US16013228
申请日：2018-06-20
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
Inventor： Dustin Christopher Cawthon , Ieng Kin Lao , Thomas Edward Dudar , Yuanpang Samuel Ding , Ying-Cheng Lo , Houzhi Luo , Michael Patrick Morrissey , Jeffrey Scott Packard
Abstract: An infusion device for dispensing fluid at a predetermined flow rate includes an elastic bladder, a pressure regulator, and a flow restrictor. The elastic bladder includes a bladder volume portion and a bladder outlet, and the elastic bladder stores fluid in the bladder volume portion and dispenses fluid through the outlet at a bladder pressure. The pressure regulator is in fluid communication with the outlet of the elastic bladder. The pressure regulator includes a fluid inlet and a fluid outlet. The fluid inlet is coupled to the bladder outlet to receive fluid from the bladder. The flow restrictor is in fluid communication with the fluid outlet. The flow restrictor and the pressure regulator cooperate to discharge fluid from the flow restrictor at a predetermined flow rate.
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