公开(公告)号：US20190382766A1

公开(公告)日：2019-12-19

申请号：US16488239

申请日：2018-02-28

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Truong Nguyen ,  Rafal Drabek ,  Alexander S. Chiu ,  Deepak Thirunavukarasu ,  Vinoth Sankarapani

IPC: C12N15/115 ,  G01N33/53

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as drug compounds, such as levamisole and cocaine.

公开(公告)号：US20190233822A1

公开(公告)日：2019-08-01

申请号：US16262769

申请日：2019-01-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Alexander S. Chiu ,  Rafal Drabek ,  Deepak Thirunavukarasu

IPC: C12N15/115 ,  C12N15/10

CPC classification number: C12N15/115 ,  C12N15/1048 ,  C12N2310/16

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as biocide molecules.

公开(公告)号：US11970785B2

公开(公告)日：2024-04-30

申请号：US17460513

申请日：2021-08-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Alexander S. Chiu ,  Rafal Drabek ,  Deepak Thirunavukarasu ,  Caitlin Bruns

IPC: C07H21/04 ,  C12Q1/6811 ,  C12Q1/6837 ,  C40B40/06

CPC classification number: C40B40/06 ,  C12Q1/6811 ,  C12Q1/6837 ,  C12Q1/6811 ,  C12Q2525/205 ,  C12Q2525/301 ,  C12Q2537/143 ,  C12Q2563/159 ,  C12Q2565/101 ,  C12Q2565/501 ,  C12Q1/6837 ,  C12Q2525/205 ,  C12Q2525/301 ,  C12Q2537/143 ,  C12Q2563/159 ,  C12Q2565/101

Abstract: This invention relates to methods and materials for multiplexed utilization of collections of functional ligands, particularly to methods and materials for selecting for and/or utilizing particular desirable traits of functional ligands in a multiplexed manner, and more particularly to methods and materials for selecting for and/or utilizing particular structural changes of functional ligands in a multiplexed manner.

公开(公告)号：US11725240B2

公开(公告)日：2023-08-15

申请号：US17152007

申请日：2021-01-19

Applicant: BASE PAIR BIOTECHNOLOGIES, INC.

Inventor： Jasmine Kaur ,  Rafal Drabek ,  George W. Jackson ,  Robert Batchelor ,  Alexander Chiu

IPC: C12N15/11 ,  C12Q1/6874 ,  C12N15/115 ,  C12N15/10 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6848 ,  C12Q1/6876 ,  C40B30/04

CPC classification number: C12Q1/6874 ,  C12N15/1048 ,  C12N15/115 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6848 ,  C12Q1/6876 ,  C40B30/04 ,  C12N2310/16 ,  C12N2330/31

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as opioids and opioid derivatives.

公开(公告)号：US11427825B2

公开(公告)日：2022-08-30

申请号：US16488239

申请日：2018-02-28

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Truong Nguyen ,  Rafal Drabek ,  Alexander S. Chiu ,  Deepak Thirunavukarasu ,  Vinoth Sankarapani

IPC: C12N15/115 ,  G01N33/53 ,  G01N33/94

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as drug compounds, such as levamisole and cocaine.

公开(公告)号：US10941444B2

公开(公告)日：2021-03-09

申请号：US16262777

申请日：2019-01-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Rafal Drabek ,  Caitlin Bruns

IPC: C12N15/11 ,  C12Q1/6874 ,  C12N15/115 ,  C12N15/10 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6848 ,  C12Q1/6876 ,  C40B30/04

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as lipoarabinomannan (LAM).

公开(公告)号：US20200172906A1

公开(公告)日：2020-06-04

申请号：US16677433

申请日：2019-11-07

Applicant: BASE PAIR BIOTECHNOLOGIES, INC.

Inventor： George W. Jackson ,  Robert Batchelor ,  Truong Nguyen ,  Victoria Singer ,  Garam Lee ,  Rafal Drabek

IPC: C12N15/115 ,  C40B10/00 ,  C40B30/04

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as molecules used proteins or peptides, such as LL37.

公开(公告)号：US20190242030A1

公开(公告)日：2019-08-08

申请号：US16262825

申请日：2019-01-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Alexander S. Chiu ,  Rafal Drabek ,  Deepak Thirunavukarasu ,  Caitlin Bruns

IPC: C40B40/06

CPC classification number: C40B40/06

Abstract: This invention relates to methods and materials for multiplexed utilization of collections of functional ligands, particularly to methods and materials for selecting for and/or utilizing particular desirable traits of functional ligands in a multiplexed manner, and more particularly to methods and materials for selecting for and/or utilizing particular structural changes of functional ligands in a multiplexed manner.