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公开(公告)号:US20240076737A1
公开(公告)日:2024-03-07
申请号:US18350916
申请日:2023-08-07
Applicant: Cepheid
Inventor: Yuh-Min CHIANG , Doug Dority , Dustin Dickens , Jennifer Glass , Reuel Van Atta
IPC: C12Q1/6876 , B01L3/00
CPC classification number: C12Q1/6876 , B01L3/502 , B01L3/5027 , B01L3/50851 , B01L7/52
Abstract: A honeycomb tube with a planar frame defining a fluidic path between a first planar surface and a second planar surface. A fluidic interface is located at one end of the planar frame. The fluidic interface has a fluidic inlet and fluidic outlet. The fluidic path further includes a well chamber having an well-substrate with a plurality of wells. The well chamber is arranged in the planar frame between the first or second surface and the well-substrate.
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公开(公告)号:US11795506B2
公开(公告)日:2023-10-24
申请号:US17103688
申请日:2020-11-24
Applicant: Cepheid
Inventor: Yuh-Min Chiang , Douglas Dority , Dustin Dickens , Jennifer Glass , Reuel Van Atta
IPC: B01L3/00 , C12Q1/6879 , C12Q1/6876 , B01L7/00
CPC classification number: C12Q1/6876 , B01L3/502 , B01L3/5027 , B01L3/50851 , B01L7/52 , B01L2200/0642 , B01L2200/0673 , B01L2300/0636 , B01L2300/0819 , B01L2400/0406 , B01L2400/0487
Abstract: A honeycomb tube with a planar frame defining a fluidic path between a first planar surface and a second planar surface. A fluidic interface is located at one end of the planar frame. The fluidic interface has a fluidic inlet and fluidic outlet. The fluidic path further includes a well chamber having an well-substrate with a plurality of wells. The well chamber is arranged in the planar frame between the first or second surface and the well-substrate. The well chamber is in fluidic communication between the pre-amplification chamber and the fluidic outlet.
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公开(公告)号:US20190225959A1
公开(公告)日:2019-07-25
申请号:US16255659
申请日:2019-01-23
Applicant: Cepheid
Inventor: Edwin Wei-Lung Lai , Reuel Van Atta , Kenneth E. Ho
IPC: C12N15/10 , C12Q1/6806 , C12Q1/6886 , G16B25/00
Abstract: Methods and reagents are provided for the rapid extraction of nucleic acids from a fixed paraffin embedded sample (e.g., a FFPET sample). In some embodiments, the methods comprise incubating one or more sections of said tissue sample in a lysis solution comprising a buffer sufficient to maintain the pH of said solution at a pH ranging from about pH 4 to about pH 9; a chaotropic agent; a chelating agent; and a detergent; where the incubating is at a temperature ranging from about 50° C. to about 100° C.; and recovering the nucleic acid from said lysis solution.
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公开(公告)号:US20180245153A1
公开(公告)日:2018-08-30
申请号:US15890154
申请日:2018-02-06
Applicant: Cepheid
Inventor: Yu-Min Chiang , Doug Dority , Dustin Dickens , Jennifer Glass , Reuel Van Atta
IPC: C12Q1/6876 , B01L3/00 , B01L7/00
CPC classification number: C12Q1/6876 , B01L3/502 , B01L3/5027 , B01L3/50851 , B01L7/52 , B01L2200/0642 , B01L2200/0673 , B01L2300/0636 , B01L2300/0819 , B01L2400/0406 , B01L2400/0487
Abstract: A honeycomb tube with a planar frame defining a fluidic path between a first planar surface and a second planar surface. A fluidic interface is located at one end of the planar frame. The fluidic interface has a fluidic inlet and fluidic outlet. The fluidic path further includes a well chamber having an well-substrate with a plurality of wells. The well chamber is arranged in the planar frame between the first or second surface and the well-substrate. The well chamber is in fluidic communication between the pre-amplification chamber and the fluidic outlet.
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公开(公告)号:US12281358B2
公开(公告)日:2025-04-22
申请号:US18350916
申请日:2023-08-07
Applicant: Cepheid
Inventor: Yuh-Min Chiang , Doug Dority , Dustin Dickens , Jennifer Glass , Reuel Van Atta
IPC: B01L3/00 , C12Q1/6876 , B01L7/00
Abstract: A honeycomb tube with a planar frame defining a fluidic path between a first planar surface and a second planar surface. A fluidic interface is located at one end of the planar frame. The fluidic interface has a fluidic inlet and fluidic outlet. The fluidic path further includes a well chamber having an well-substrate with a plurality of wells. The well chamber is arranged in the planar frame between the first or second surface and the well-substrate.
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公开(公告)号:US11299726B2
公开(公告)日:2022-04-12
申请号:US16255659
申请日:2019-01-23
Applicant: Cepheid
Inventor: Edwin Wei-Lung Lai , Reuel Van Atta , Kenneth E. Ho
IPC: C12Q1/68 , C12N15/10 , G16B25/00 , G16B25/10 , C12Q1/6806 , C12Q1/6886 , G01N1/06
Abstract: Methods and reagents are provided for the rapid extraction of nucleic acids from a fixed paraffin embedded sample (e.g., a FFPET sample). In some embodiments, the methods comprise incubating one or more sections of said tissue sample in a lysis solution comprising a buffer sufficient to maintain the pH of said solution at a pH ranging from about pH 4 to about pH 9; a chaotropic agent; a chelating agent; and a detergent; where the incubating is at a temperature ranging from about 50° C. to about 100° C.; and recovering the nucleic acid from said lysis solution.
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公开(公告)号:US20210164044A1
公开(公告)日:2021-06-03
申请号:US16992392
申请日:2020-08-13
Applicant: Cepheid
Inventor: YUH-MIN CHIANG , Doug Dority , Dustin Dickens , Jennifer Glass , Reuel Van Atta
IPC: C12Q1/6876 , B01L3/00
Abstract: A honeycomb tube with a planar frame defining a fluidic path between a first planar surface and a second planar surface. A fluidic interface is located at one end of the planar frame. The fluidic interface has a fluidic inlet and fluidic outlet. The fluidic path further includes a well chamber having an well-substrate with a plurality of wells. The well chamber is arranged in the planar frame between the first or second surface and the well-substrate.
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公开(公告)号:US20210147933A1
公开(公告)日:2021-05-20
申请号:US17103688
申请日:2020-11-24
Applicant: Cepheid
Inventor: Yuh-Min Chiang , Douglas Dority , Dustin Dickens , Jennifer Glass , Reuel Van Atta
IPC: C12Q1/6876 , B01L3/00
Abstract: A honeycomb tube with a planar frame defining a fluidic path between a first planar surface and a second planar surface. A fluidic interface is located at one end of the planar frame. The fluidic interface has a fluidic inlet and fluidic outlet. The fluidic path further includes a well chamber having an well-substrate with a plurality of wells. The well chamber is arranged in the planar frame between the first or second surface and the well-substrate. The well chamber is in fluidic communication between the pre-amplification chamber and the fluidic outlet.
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公开(公告)号:US09914968B2
公开(公告)日:2018-03-13
申请号:US13843739
申请日:2013-03-15
Applicant: Cepheid
Inventor: Yuh-Min Chiang , Doug Dority , Dustin Dickens , Jennifer Glass , Reuel Van Atta
CPC classification number: C12Q1/6876 , B01L3/502 , B01L3/5027 , B01L3/50851 , B01L7/52 , B01L2200/0642 , B01L2200/0673 , B01L2300/0636 , B01L2300/0819 , B01L2400/0406 , B01L2400/0487
Abstract: A honeycomb tube with a planar frame defining a fluidic path between a first planar surface and a second planar surface. A fluidic interface is located at one end of the planar frame. The fluidic interface has a fluidic inlet and fluidic outlet. The fluidic path further includes a well chamber having an well-substrate with a plurality of wells. The well chamber is arranged in the planar frame between the first or second surface and the well-substrate. The well chamber is in fluidic communication between the pre-amplification chamber and the fluidic outlet.
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公开(公告)号:US20150275292A1
公开(公告)日:2015-10-01
申请号:US14431259
申请日:2013-09-26
Applicant: CEPHEID
Inventor: Yuh-Min Chiang , Doug Dority , Dustin Dickens , Jennifer Glass , Reuel Van Atta
IPC: C12Q1/68
CPC classification number: C12Q1/6876 , B01L3/502 , B01L3/5027 , B01L3/50851 , B01L7/52 , B01L2200/0642 , B01L2200/0673 , B01L2300/0636 , B01L2300/0819 , B01L2400/0406 , B01L2400/0487
Abstract: A honeycomb tube with a planar frame defining a fluidic path between a first planar surface and a second planar surface. A fluidic interface is located at one end of the planar frame. The fluidic interface has a fluidic inlet and fluidic outlet. The fluidic path further includes a well chamber having an well-substrate with a plurality of wells. The well chamber is arranged in the planar frame between the first or second surface and the well-substrate.
Abstract translation: 一种蜂窝管,其具有限定在第一平面和第二平面之间的流体路径的平面框架。 流体界面位于平面框架的一端。 流体界面具有流体入口和流体出口。 流体路径还包括具有多个孔的具有良好基底的井室。 阱室布置在第一或第二表面和阱基板之间的平面框架中。
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