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公开(公告)号:US20150231326A1
公开(公告)日:2015-08-20
申请号:US14621501
申请日:2015-02-13
Applicant: Cook Medical Technologies LLC
Inventor: Keith R. Milner , Triona Campbell, JR.
IPC: A61M5/14
CPC classification number: A61M5/14 , A61F2/01 , A61F2/15 , A61F9/0008 , A61M25/007 , A61M25/0074 , A61M25/04 , A61M2025/0057
Abstract: A drug delivery device is provided for directly treating a treatment site. The device allows body fluids to perfuse past the device while it is expanded to increase the amount of treatment time that is possible. The drug is delivered through a hollow helical tube that extends around a support structure. The hollow tube includes a series of lateral holes to allow the drug to directly reach the desired treatment site.
Abstract translation: 提供用于直接治疗治疗部位的药物输送装置。 该装置允许体液在膨胀时灌注穿过装置,以增加可能的治疗时间量。 药物通过围绕支撑结构延伸的中空螺旋管递送。 中空管包括一系列侧孔,以允许药物直接到达所需的治疗部位。
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12.
公开(公告)号:US20150209483A1
公开(公告)日:2015-07-30
申请号:US14683486
申请日:2015-04-10
Applicant: COOK MEDICAL TECHNOLOGIES LLC
Inventor: Keith R. Milner , James M. Carlson , Steven Charlebois , Krista N. Gearhart , Richard A. Swift
CPC classification number: A61L31/08 , A61F2/82 , A61F2210/0004 , A61F2210/0076 , A61L31/022 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61L2300/62 , A61L2420/02
Abstract: One aspect provides implantable medical devices including a bioabsorbable structure having a surface and having a coating layer on at least a portion of the surface. In certain embodiments, the coating layer includes a releasable bioactive and provides for a controlled absorption of the bioabsorbable structure upon implantation in a human or veterinary patient. Another aspect provides methods treating a disease including implanting such a device in a vessel of a human or veterinary patient.
Abstract translation: 一个方面提供了包括具有表面并且在表面的至少一部分上具有涂层的生物可吸收结构的可植入医疗装置。 在某些实施方案中,涂层包括可释放的生物活性物质,并且在植入人或兽医患者体内时提供对生物可吸收结构的受控吸收。 另一方面提供了治疗疾病的方法,包括将这种装置植入人或兽医患者的血管。
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公开(公告)号:US20140243843A1
公开(公告)日:2014-08-28
申请号:US14139024
申请日:2013-12-23
Applicant: Cook Medical Technologies LLC
Inventor: William J. Havel , Steven J. Charlebois , Keith R. Milner
CPC classification number: A61F2/958 , A61F2002/9586 , A61M25/1002 , A61M25/1006 , A61M25/1018 , A61M2025/1084
Abstract: A balloon catheter assembly including a catheter, a sleeve, and a balloon. The catheter has a body, an exterior surface, a lumen, a port providing fluid communication between the lumen and the exterior surface, and a coupling mechanism to couple the lumen to an inflation source. The sleeve has an interior surface facing the exterior surface, the sleeve being coaxial with the catheter and configured to move longitudinally about the catheter. The balloon is disposed about the catheter and has a middle segment covering the port, a distal segment coupled to the sleeve, and a proximal segment coupled to the catheter. The middle segment has a middle longitudinal stiffness, the distal segment has a distal longitudinal stiffness, and the proximal segment has a proximal longitudinal stiffness. The middle longitudinal stiffness is greater than the proximal longitudinal stiffness and the middle longitudinal stiffness is greater than the distal longitudinal stiffness.
Abstract translation: 包括导管,套筒和气囊的气囊导管组件。 导管具有主体,外表面,内腔,在内腔和外表面之间提供流体连通的端口,以及将内腔连接到充气源的联接机构。 套筒具有面向外表面的内表面,套筒与导管同轴并且构造成围绕导管纵向移动。 气囊围绕导管设置,并且具有覆盖端口的中间段,联接到套筒的远侧段和联接到导管的近端段。 中段具有中纵向刚度,远端段具有远端纵向刚度,近端段具有近端纵向刚度。 中纵向刚度大于近端纵向刚度,中纵向刚度大于远侧纵向刚度。
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14.
公开(公告)号:US20140180398A1
公开(公告)日:2014-06-26
申请号:US13788056
申请日:2013-03-07
Applicant: Cook Medical Technologies LLC
Inventor: Keith R. Milner , James M. Carlson , Steven Charlebois , Krista N. Gearhart , Richard A. Swift
IPC: A61F2/82
CPC classification number: A61L31/08 , A61F2/82 , A61F2210/0004 , A61F2210/0076 , A61L31/022 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61L2300/62 , A61L2420/02
Abstract: One aspect provides implantable medical devices including a bioabsorbable structure having a surface and having a coating layer on at least a portion of the surface. In certain embodiments, the coating layer includes a releasable bioactive and provides for a controlled absorption of the bioabsorbable structure upon implantation in a human or veterinary patient. Another aspect provides methods treating a disease including implanting such a device in a vessel of a human or veterinary patient.
Abstract translation: 一个方面提供了包括具有表面并且在表面的至少一部分上具有涂层的生物可吸收结构的可植入医疗装置。 在某些实施方案中,涂层包括可释放的生物活性物质,并且在植入人或兽医患者体内时提供对生物可吸收结构的受控吸收。 另一方面提供了治疗疾病的方法,包括将这种装置植入人或兽医患者的血管。
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公开(公告)号:US10231856B2
公开(公告)日:2019-03-19
申请号:US15335734
申请日:2016-10-27
Applicant: Cook Medical Technologies LLC
Inventor: Keith R. Milner , Richard A. Swift , Reza Shirazi
Abstract: Examples of a stent is provided with interlocking joints removably coupling adjacent axial stent segments. Mating elements forming the interlocking joints maintain circumferential and axial engagement when the stent is in the radially compressed configuration, for example, during tracking of the stent to a treatment site of a body vessel, and become disengaged during radial expansion of the stent. The length of mating elements may be sized as large as the strut width. When disengaged, the disconnected the axial stent segments remain discrete stent structures separated from one another along the point of treatment.
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公开(公告)号:US20190021885A1
公开(公告)日:2019-01-24
申请号:US16033453
申请日:2018-07-12
Applicant: COOK MEDICAL TECHNOLOGIES LLC
Inventor: Woong Kim , Keith R. Milner , Richard A. Swift
Abstract: Examples of a stent are provided with interlocking joints removably coupling adjacent axial stent segments. Mating elements forming the interlocking joints maintain engagement when the stent is in the radially compressed configuration, for example, during tracking of the stent to a treatment site of a body vessel, and become disengaged during radial expansion of the stent. When disengaged, the disconnected the axial stent segments remain discrete stent structures separated from one another along the point of treatment.
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公开(公告)号:US20180333560A1
公开(公告)日:2018-11-22
申请号:US15978628
申请日:2018-05-14
Applicant: Cook Medical Technologies LLC
Inventor: Keith R. Milner
CPC classification number: A61M25/0136 , A61M25/0113 , A61M25/09041
Abstract: A handle is provided for advancing a wire through a catheter, the handle including a handle body, a first wheel, a second wheel, and a coupling mechanism. The handle body has an outer surface and an inner surface. The inner surface defines a lumen extending along a longitudinal axis from a proximal end to a distal end. The first wheel is coupled to a first side of the handle body. A portion of the first wheel is movable toward the longitudinal axis into a first lumen side of the lumen to an engagement position to contact the wire. A second wheel is coupled to a second side of the handle body. A portion of the second wheel is adapted to extend into a second lumen side of the lumen which is different from the first lumen side.
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18.
公开(公告)号:US20180161121A1
公开(公告)日:2018-06-14
申请号:US15837203
申请日:2017-12-11
Applicant: Cook Medical Technologies LLC
Inventor: James Butler , Melissa Lonn , Keith R. Milner , John Neilan
IPC: A61B90/00 , C22F1/16 , B32B15/01 , C22F1/10 , B21C1/02 , A61B17/22 , A61B17/221 , A61B17/34 , A61C7/20 , A61F2/01 , A61F2/07 , A61B17/00 , A61F2/86 , A61M25/00
CPC classification number: A61B90/39 , A61B17/0057 , A61B17/1214 , A61B17/22031 , A61B17/221 , A61B17/3415 , A61B2017/00358 , A61B2017/00526 , A61B2017/00831 , A61B2017/00867 , A61B2090/3966 , A61C7/20 , A61C2201/005 , A61C2201/007 , A61F2/013 , A61F2/07 , A61F2/82 , A61F2/86 , A61F2002/016 , A61F2240/001 , A61F2250/0098 , A61L29/123 , A61L29/18 , A61L31/124 , A61L31/18 , A61M25/0012 , A61M25/005 , A61M25/0108 , A61M2025/0063 , A61M2025/09108 , A61M2025/09133 , A61M2025/09141 , A61M2025/09166 , B21C1/02 , B21C23/22 , B32B15/01 , C22C19/03 , C22F1/10 , C22F1/16
Abstract: A radiopaque composite wire for medical applications has a core comprising a rare earth metal, an outer layer comprising a nickel-titanium alloy disposed over the core, and a controlled diffusion zone between the core and the outer layer. The controlled diffusion zone includes at least one compound phase comprising (a) the rare earth metal and (b) nickel and/or titanium.
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公开(公告)号:US20180116835A1
公开(公告)日:2018-05-03
申请号:US15335734
申请日:2016-10-27
Applicant: Cook Medical Technologies LLC
Inventor: Keith R. Milner , Richard A. Swift , Reza Shirazi
CPC classification number: A61F2/915 , A61F2/844 , A61F2/89 , A61F2/958 , A61F2002/826 , A61F2002/91558 , A61F2002/91591 , A61F2220/0033
Abstract: Examples of a stent is provided with interlocking joints removably coupling adjacent axial stent segments. Mating elements forming the interlocking joints maintain circumferential and axial engagement when the stent is in the radially compressed configuration, for example, during tracking of the stent to a treatment site of a body vessel, and become disengaged during radial expansion of the stent. The length of mating elements may be sized as large as the strut width. When disengaged, the disconnected the axial stent segments remain discrete stent structures separated from one another along the point of treatment.
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公开(公告)号:US10702406B2
公开(公告)日:2020-07-07
申请号:US15936753
申请日:2018-03-27
Applicant: COOK MEDICAL TECHNOLOGIES LLC
Inventor: Richard A. Swift , Keith R. Milner , James C. Merk
Abstract: A prosthesis is disclosed including an expandable frame having a first region and a second region coupled to one another. The first region includes a transition segment and a flex segment. The stent members of the transition segment have proximal and distal apices arranged in a peak-to-peak relationship with one another. At least a portion of proximal and distal apices of the transition segment remains uncoupled to one another. The flex segment includes a stent member having proximal and distal apices arranged in a peak-to-valley relationship with the transition segment. Longitudinal tie bars are intermittently coupled between apices the flex segment and the transition segment at coupling joints. The coupling joint is located where the proximal and distal apices of the stent members of the transition segment remain uncoupled to one another. The transition and flex segments may form an alternating pattern. A flareable proximal portion may be included.
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