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公开(公告)号：US10506948B2
公开(公告)日：2019-12-17
申请号：US14127136
申请日：2012-07-05
摘要： A system (10) can localize an object in a patient's body. The system (10) can include a pulse generator (18 or 30) configured to provide a localization signal to at least one electrode that is fixed to the object in the patient's body. A sensor array (22) can be configured to detect an electrical field produced in response to the localization signal and provide respective sensor signals. A map generator (42) can be configured to reconstruct electrical signals based on the respective sensor signals and geometry data representing a geometric relationship between patient anatomy and the sensor array. A location calculator (50) can determine a location where the localization signal was applied based on the reconstructed electrical signals.
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公开(公告)号：US09504427B2
公开(公告)日：2016-11-29
申请号：US14115235
申请日：2012-05-04
IPC分类号： G01N33/48 , A61B5/00 , A61B5/0402 , A61B5/0452 , G06K9/00 , G06G7/58 , A61B5/0408 , A61B5/042
CPC分类号： A61B5/7235 , A61B5/04028 , A61B5/04085 , A61B5/0422 , A61B5/04525 , A61B5/7203 , A61B5/7221 , A61B5/7278 , G06K9/0051 , G06K9/00543
摘要： A method (500) can comprise performing principal component analysis (PCA) on data corresponding to a subset of a plurality of signals and a selected template to generate a virtual lead and an optimized template (530). The method can also comprise calculating a cross correlation on the virtual lead and the optimized template to determine a strength of linear dependence between the virtual lead and the optimized template to determine regions of interest (ROIs) of the virtual lead (540). The method can further comprise detecting peak correlation coefficients in the virtual lead (550). The method can still further comprise comparing the amplitude of each of the ROIs of the virtual lead with the selected template to determine an error between the template and each ROI of the virtual lead (560). The method can yet further comprise averaging the ROIs to generate averaged data (570).
摘要翻译： 方法（500）可以包括对与多个信号的子集对应的数据和所选择的模板执行主成分分析（PCA），以生成虚拟引导和优化的模板（530）。 该方法还可以包括计算虚拟引线和优化模板上的互相关，以确定虚拟引线和优化模板之间的线性依赖性的强度，以确定虚拟引线（540）的感兴趣区域（ROI）。 该方法还可以包括检测虚拟引线中的峰值相关系数（550）。 该方法还可以包括将虚拟引线的每个ROI的幅度与所选择的模板进行比较，以确定模板与虚拟引线的每个ROI之间的误差（560）。 该方法还可以包括平均ROI以产生平均数据（570）。
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公开(公告)号：US09241675B2
公开(公告)日：2016-01-26
申请号：US13829631
申请日：2011-09-16
申请人： Remi Dubois , Harold Wodlinger , Charulatha Ramanathan , Brian P. George , Pierre Roussel-Ragot
发明人： Remi Dubois , Harold Wodlinger , Charulatha Ramanathan , Brian P. George , Pierre Roussel-Ragot
摘要： Systems and methods can be used to determine activation information for points along a surface or selected region of interest. In one example, a computer-readable medium having computer-executable instructions for performing a method that includes computing a local activation vector based on relative timing among electrical signals corresponding to neighboring points of a plurality of points on a surface envelope. An activation time can be computed for each of the plurality of points as a function of corresponding local activation vectors.
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公开(公告)号：US20140067279A1
公开(公告)日：2014-03-06
申请号：US14115235
申请日：2012-05-04
IPC分类号： A61B5/00
CPC分类号： A61B5/7235 , A61B5/04028 , A61B5/04085 , A61B5/0422 , A61B5/04525 , A61B5/7203 , A61B5/7221 , A61B5/7278 , G06K9/0051 , G06K9/00543
摘要： A method (500) can comprise performing principal component analysis (PCA) on data corresponding to a subset of a plurality of signals and a selected template to generate a virtual lead and an optimized template (530). The method can also comprise calculating a cross correlation on the virtual lead and the optimized template to determine a strength of linear dependence between the virtual lead and the optimized template to determine regions of interest (ROIs) of the virtual lead (540). The method can further comprise detecting peak correlation coefficients in the virtual lead (550). The method can still further comprise comparing the amplitude of each of the ROIs of the virtual lead with the selected template to determine an error between the template and each ROI of the virtual lead (560). The method can yet further comprise averaging the ROIs to generate averaged data (570).
摘要翻译： 方法（500）可以包括对与多个信号的子集对应的数据和所选择的模板执行主成分分析（PCA），以生成虚拟引导和优化的模板（530）。 该方法还可以包括计算虚拟引线和优化模板上的互相关，以确定虚拟引线和优化模板之间的线性依赖性的强度，以确定虚拟引线（540）的感兴趣区域（ROI）。 该方法还可以包括检测虚拟引线中的峰值相关系数（550）。 该方法还可以包括将虚拟引线的每个ROI的幅度与所选择的模板进行比较，以确定模板与虚拟引线的每个ROI之间的误差（560）。 该方法还可以包括平均ROI以产生平均数据（570）。
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公开(公告)号：US09271680B2
公开(公告)日：2016-03-01
申请号：US13829631
申请日：2011-09-16
申请人： Remi Dubois , Harold Wodlinger , Charulatha Ramanathan , Brian P. George , Pierre Roussel-Ragot
发明人： Remi Dubois , Harold Wodlinger , Charulatha Ramanathan , Brian P. George , Pierre Roussel-Ragot
CPC分类号： A61B5/04012 , A61B5/0044 , A61B5/04011 , A61B5/042 , A61B5/0422 , A61B5/044 , A61B5/0452 , A61B5/0478 , A61B5/6823 , A61B5/7271 , A61B5/743 , G16H50/50
摘要： Systems and methods can be used to determine activation information for points along a surface or selected region of interest. In one example, a computer-readable medium having computer-executable instructions for performing a method that includes computing a local activation vector based on relative timing among electrical signals corresponding to neighboring points of a plurality of points on a surface envelope. An activation time can be computed for each of the plurality of points as a function of corresponding local activation vectors.
摘要翻译： 系统和方法可以用于确定沿着表面或所选择的感兴趣区域的点的激活信息。 在一个示例中，一种具有用于执行方法的计算机可执行指令的计算机可读介质，所述方法包括基于对应于表面信封上的多个点的相邻点的电信号之间的相对定时来计算本地激活向量。 作为对应的局部激活向量的函数，可以针对多个点中的每个点计算激活时间。
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公开(公告)号：US20110206256A1
公开(公告)日：2011-08-25
申请号：US13128136
申请日：2009-11-09
IPC分类号： G06K9/00
CPC分类号： A61B5/042 , A61B5/04021 , A61B2018/00839 , G06F19/00 , G16H40/63 , G16H50/50
摘要： Systems and methods can be utilized to visualize physiological data relative to a surface region (e.g., an organ) of a patient. A computer-implemented method can include storing electroanatomic data in memory representing electrical activity for a predetermined surface region of the patient and providing an interactive graphical representation of the predetermined surface region of the patient. A user input is received to define location data corresponding to a user-selected location for at least one virtual electrode on the graphical representation of the predetermined surface region of the patient. A visual representation of physiological data for the predetermined surface region of the patient is generated based on the location data and the electroanatomic data.
摘要翻译： 系统和方法可用于相对于患者的表面区域（例如器官）可视化生理数据。 计算机实现的方法可以包括将电原子数据存储在表示患者的预定表面区域的电活动的存储器中，并提供患者的预定表面区域的交互式图形表示。 接收用户输入以在患者的预定表面区域的图形表示上定义对应于至少一个虚拟电极的用户选择位置的位置数据。 基于位置数据和电子解剖数据生成患者的预定表面区域的生理数据的视觉表示。
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公开(公告)号：US06975900B2
公开(公告)日：2005-12-13
申请号：US10317953
申请日：2002-12-12
申请人： Yoram Rudy , Charulatha Ramanathan , Raja Ghanem , Ping Jia
发明人： Yoram Rudy , Charulatha Ramanathan , Raja Ghanem , Ping Jia
IPC分类号： A61B5/04 , A61B5/0402 , A61B5/0408 , A61B5/042 , A61B5/05 , A61B5/055 , A61B6/03 , A61B6/12 , A61B8/08 , G06F17/00 , A61B5/044
CPC分类号： A61B5/0402 , A61B5/04011 , A61B5/04085 , A61B5/0422 , A61B5/055 , A61B5/6805 , A61B5/6852 , A61B5/6855 , A61B5/6856 , A61B5/6857 , A61B6/032 , A61B6/12 , A61B6/503 , A61B6/541 , A61B6/584 , A61B8/08 , A61B8/0833 , A61B2034/2053 , Y10S128/92
摘要： Methods and systems for determining a surface geometry of an object, including determining a first projection matrix based on a first imaging device, determining a second projection matrix based on a second imaging device, obtaining at least one first two-dimensional (2D) image of the object using the first imaging device, obtaining at least one second 2D image of the object using the second imaging device, determining a contour of the object in the first 2D image and the second 2D image, and, based on the at least two contours, the first projection matrix, and the second projection matrix, reconstructing 3D data associated with the surface of the object. In one embodiment, the object can be a heart.
摘要翻译： 用于确定对象的表面几何形状的方法和系统，包括基于第一成像装置确定第一投影矩阵，基于第二成像装置确定第二投影矩阵，获得至少一个第一二维（2D）图像 使用第一成像装置的对象，使用第二成像装置获得对象的至少一个第二2D图像，确定第一2D图像和第二2D图像中的对象的轮廓，以及基于至少两个轮廓 ，第一投影矩阵和第二投影矩阵，重构与对象的表面相关联的3D数据。 在一个实施例中，对象可以是心脏。
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公开(公告)号：US07471973B2
公开(公告)日：2008-12-30
申请号：US11112128
申请日：2005-04-21
申请人： Yoram Rudy , Charulatha Ramanathan , Raja Ghanem , Ping Jia
发明人： Yoram Rudy , Charulatha Ramanathan , Raja Ghanem , Ping Jia
IPC分类号： A61B5/044
CPC分类号： A61B5/0402 , A61B5/04011 , A61B5/04085 , A61B5/0422 , A61B5/055 , A61B5/6805 , A61B5/6852 , A61B5/6855 , A61B5/6856 , A61B5/6857 , A61B6/032 , A61B6/12 , A61B6/503 , A61B6/541 , A61B6/584 , A61B8/08 , A61B8/0833 , A61B2034/2053 , Y10S128/92
摘要： Methods for determining a surface geometry of an object, including determining a first projection matrix based on a first imaging device, determining a second projection matrix based on a second imaging device, obtaining at least one first two-dimensional (2D) image of the object using the first imaging device, obtaining at least one second 2D image of the object using the second imaging device, determining a contour of the object in the first 2D image and the second 2D image, and, based on the at least two contours, the first projection matrix, and the second projection matrix, reconstructing 3D data associated with the surface of the object. In one embodiment, the object can be a heart.
摘要翻译： 用于确定对象的表面几何形状的方法，包括基于第一成像装置确定第一投影矩阵，基于第二成像装置确定第二投影矩阵，获得所述对象的至少一个第一二维（2D）图像 使用第一成像装置，使用第二成像装置获得对象的至少一个第二2D图像，确定第一2D图像和第二2D图像中的对象的轮廓，并且基于至少两个轮廓， 第一投影矩阵和第二投影矩阵，重建与物体表面相关联的3D数据。 在一个实施例中，对象可以是心脏。
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公开(公告)号：US07016719B2
公开(公告)日：2006-03-21
申请号：US10264572
申请日：2002-10-04
申请人： Yoram Rudy , Charulatha Ramanathan , Raja Ghanem , Ping Jia
发明人： Yoram Rudy , Charulatha Ramanathan , Raja Ghanem , Ping Jia
IPC分类号： A61B5/04
CPC分类号： A61B5/0402 , A61B5/04011 , A61B5/04085 , A61B5/0422 , A61B5/055 , A61B5/6805 , A61B5/6852 , A61B5/6855 , A61B5/6856 , A61B5/6857 , A61B6/032 , A61B6/12 , A61B6/503 , A61B8/08 , A61B8/0833 , A61B2034/2053 , G06K9/0057
摘要： Methods and systems for computing epicardial surface electric potentials based on measured body surface electric potentials, where the methods and systems include representing at least one geometric relationship between at least one body surface electric potential measuring system and the epicardial surface as a multidimensional matrix, estimating an inverse of the multidimensional matrix based on a Generalized Minimum Residual (GMRes) method, and, based on the inverse matrix and the measured body surface potentials, determining the epicardial surface electric potentials.
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公开(公告)号：US20050197587A1
公开(公告)日：2005-09-08
申请号：US11112128
申请日：2005-04-21
申请人： Yoram Rudy , Charulatha Ramanathan , Raja Ghanem , Ping Jia
发明人： Yoram Rudy , Charulatha Ramanathan , Raja Ghanem , Ping Jia
IPC分类号： A61B5/04 , A61B5/0402 , A61B5/0408 , A61B5/042 , A61B5/05 , A61B5/055 , A61B6/03 , A61B6/12 , A61B8/08 , G06F17/00
CPC分类号： A61B5/0402 , A61B5/04011 , A61B5/04085 , A61B5/0422 , A61B5/055 , A61B5/6805 , A61B5/6852 , A61B5/6855 , A61B5/6856 , A61B5/6857 , A61B6/032 , A61B6/12 , A61B6/503 , A61B6/541 , A61B6/584 , A61B8/08 , A61B8/0833 , A61B2034/2053 , Y10S128/92
摘要： Methods for determining a surface geometry of an object, including determining a first projection matrix based on a first imaging device, determining a second projection matrix based on a second imaging device, obtaining at least one first two-dimensional (2D) image of the object using the first imaging device, obtaining at least one second 2D image of the object using the second imaging device, determining a contour of the object in the first 2D image and the second 2D image, and, based on the at least two contours, the first projection matrix, and the second projection matrix, reconstructing 3D data associated with the surface of the object. In one embodiment, the object can be a heart.
摘要翻译： 用于确定对象的表面几何形状的方法，包括基于第一成像装置确定第一投影矩阵，基于第二成像装置确定第二投影矩阵，获得至少一个第一二维（2D）图像 使用第一成像装置的对象，使用第二成像装置获得对象的至少一个第二2D图像，确定第一2D图像和第二2D图像中的对象的轮廓，并且至少基于 两个轮廓，第一投影矩阵和第二投影矩阵，重建与物体表面相关联的3 D数据。 在一个实施例中，对象可以是心脏。
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