公开(公告)号：US09790522B2

公开(公告)日：2017-10-17

申请号：US14680195

申请日：2015-04-07

Applicant: Coskata, Inc.

Inventor： Andrew Reeves ,  Richard Tobey ,  Mike Enzien

IPC: C12N1/02 ,  C12P7/16 ,  C12P1/04 ,  C12P7/06 ,  C12P7/08 ,  C12R1/145 ,  C12P39/00 ,  A61K38/00

CPC classification number: C12P7/16 ,  C12P7/065 ,  C12P7/08 ,  C12P39/00 ,  C12R1/145 ,  C12Y102/07005 ,  Y02E50/10 ,  Y02E50/17

Abstract: The invention relates to the fields of bacterial metabolism and the utilization or consumption of short-chain carboxylic acids to reduced products. Specifically, it relates to syngas fermentations using monocultures of syngas-utilizing homoacetogenic bacteria for the production of alcohols using native alcohol dehydrogenase.

公开(公告)号：US20160298143A1

公开(公告)日：2016-10-13

申请号：US14680195

申请日：2015-04-07

Applicant: Coskata, Inc.

Inventor： Andrew Reeves ,  Richard Tobey ,  Mike Enzien

IPC: C12P7/16 ,  C12P7/06

CPC classification number: C12P7/16 ,  C12P7/065 ,  C12P7/08 ,  C12P39/00 ,  C12R1/145 ,  C12Y102/07005 ,  Y02E50/10 ,  Y02E50/17

Abstract: The invention relates to the fields of bacterial metabolism and the utilization or consumption of short-chain carboxylic acids to reduced products. Specifically, it relates to syngas fermentations using monocultures of syngas-utilizing homoacetogenic bacteria for the production of alcohols using native alcohol dehydrogenase.

Abstract translation: 本发明涉及细菌代谢领域和短链羧酸对还原产物的利用或消耗。 具体地说，本发明涉及使用合成气合成气合并嗜酸性细菌用于使用天然醇脱氢酶生产醇的合成气发酵。

公开(公告)号：US20160010118A1

公开(公告)日：2016-01-14

申请号：US14327165

申请日：2014-07-09

Applicant: Coskata, Inc.

Inventor： Andrew Reeves ,  Robert Hickey

IPC: C12P7/16 ,  C12P7/06 ,  C12P7/14 ,  C12P7/04

CPC classification number: C12P7/16 ,  C12N1/20 ,  C12P7/04 ,  C12P7/065 ,  Y02E50/10 ,  Y02E50/17

Abstract: The methods are disclosed for sustaining a population of microorganisms in an aqueous fermentation broth used in a process to convert syngas to alcohol when the supply of syngas is decreased or ceased. The methods involve supplying at least one reducible anion in a rate an amount sufficient to maintain the population of microorganisms.

Abstract translation: 公开了用于在合成气的供应减少或停止时在用于将合成气转化为醇的方法中使用的水性发酵液中维持微生物群的方法。 所述方法包括以足以维持微生物群体的量提供至少一种可还原阴离子。

公开(公告)号：US20140273236A1

公开(公告)日：2014-09-18

申请号：US14209634

申请日：2014-03-13

Applicant: Coskata, Inc.

Inventor： Andrew Reeves

IPC: C12N15/87

CPC classification number: C12N15/74 ,  C12N9/1007 ,  C12N15/63 ,  C12N15/70 ,  C12N15/87 ,  C12Q2521/331 ,  C12Y201/01072

Abstract: This invention provides isolated polynucleotides encoding DNA Type I methyltransferase and uses thereof for improving transformation efficiencies of exogenous and endogenous plasmid DNA into Clostridial hosts.

Abstract translation: 本发明提供编码DNA I型甲基转移酶的分离的多核苷酸及其用于提高外源和内源质粒DNA转化成梭菌宿主的转化效率的用途。