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公开(公告)号:US20060013832A1
公开(公告)日:2006-01-19
申请号:US11029188
申请日:2005-01-04
Applicant: Carl June , Craig Thompson , Gary Nabel , Gary Gray , Paul Rennert
Inventor: Carl June , Craig Thompson , Gary Nabel , Gary Gray , Paul Rennert
CPC classification number: C12N5/0636 , A61K35/17 , A61K38/00 , A61K39/02 , A61K39/12 , A61K48/00 , A61K2039/505 , A61K2039/507 , A61K2039/5158 , C07K14/705 , C07K14/70521 , C07K14/70532 , C07K16/00 , C07K16/2806 , C07K16/2809 , C07K16/2812 , C07K16/2815 , C07K16/2818 , C07K16/2833 , C07K16/2866 , C07K16/289 , C07K16/2896 , C07K2317/24 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/73 , C07K2317/74 , C07K2319/00 , C07K2319/30 , C12N2501/51 , C12N2501/515 , C12N2501/599 , C12N2710/00088 , C12N2740/16011
Abstract: Methods for inducing a population of T cells to proliferate by activating the population of T cells and stimulating an accessory molecule on the surface of the T cells with a ligand which binds the accessory molecule are described. T cell proliferation occurs in the absence of exogenous growth factors or accessory cells. T cell activation is accomplished by stimulating the T cell receptor (TCR)/CD3 complex or the CD2 surface protein. To induce proliferation of an activated population T cells, an accessory molecule on the surface of the T cells, such as CD28, is stimulated with a ligand which binds the accessory molecule. The T cell population expanded by the method of the invention can be genetically transduced and used for immunotherapy or can be used in methods of diagnosis.
Abstract translation: 描述了通过激活T细胞群并用结合附属分子的配体刺激T细胞表面上的辅助分子来诱导T细胞群体增殖的方法。 T细胞增殖发生在没有外源生长因子或附属细胞的情况下。 通过刺激T细胞受体(TCR)/ CD3复合物或CD2表面蛋白来完成T细胞活化。 为了诱导活化的群体T细胞的增殖,T细胞表面上的辅助分子如CD28被与配合分子结合的配体刺激。 通过本发明的方法扩增的T细胞群体可以被遗传转导并用于免疫治疗,或可用于诊断方法。
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公开(公告)号:US20160257105A1
公开(公告)日:2016-09-08
申请号:US14640248
申请日:2015-03-06
Applicant: Craig Thompson , Pamela Thompson
Inventor: Craig Thompson , Pamela Thompson
CPC classification number: B32B38/10 , B32B2310/049 , B32B2519/00 , B44C7/027 , Y10S156/929 , Y10S156/94 , Y10T156/1126 , Y10T156/1153 , Y10T156/1911 , Y10T156/1928
Abstract: A decal removal assembly includes a plate that is structured to have a steam space extending therein. The plate may be positioned proximate a surface such that the steam space surrounds a decal adhered to the surface. A handle is attached to the plate and the handle is in fluid communication with the steam space. A nozzle is attached to the handle and the nozzle has a distal end with respect to the handle. The nozzle is in fluid communication with the steam space and the distal end may be fluidly coupled to a steam source. Steam from the steam source is directed into the steam space thereby facilitating removal of the decal from the surface. A plurality of couplers is provided and each of the couplers is attached to the plate. Each of the couplers engages the surface such that the plate is retained on the surface and each of the couplers is positioned proximate one of four corners of the plate.
Abstract translation: 贴花去除组件包括被构造成具有在其中延伸的蒸汽空间的板。 板可以靠近表面定位,使得蒸汽空间围绕附着在表面上的贴花。 手柄连接到板上,手柄与蒸汽空间流体连通。 喷嘴连接到手柄,并且喷嘴相对于手柄具有远端。 喷嘴与蒸汽空间流体连通,并且远端可以流体地联接到蒸汽源。 来自蒸汽源的蒸汽被引导到蒸汽空间中,从而有助于从表面去除贴花。 提供多个耦合器并且每个耦合器附接到板。 每个耦合器接合表面,使得板被保持在表面上,并且每个耦合器位于板的四个角中的一个附近。
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公开(公告)号:US20110097678A1
公开(公告)日:2011-04-28
申请号:US12924808
申请日:2010-10-05
Applicant: Keith D. Patch , Linda A. Tempelman , Simon G. Stone , Craig Thompson
Inventor: Keith D. Patch , Linda A. Tempelman , Simon G. Stone , Craig Thompson
IPC: F24C15/00
CPC classification number: F23C13/08 , A61F7/12 , A61F2007/126 , A61M5/44 , A61M2205/364 , F23D91/04
Abstract: Method of heating and heating apparatus. According to one embodiment, the heating apparatus is designed for warming infusion fluids and includes a pair of catalytic heaters positioned around a cartridge containing the infusion fluid. Each catalytic heater includes a pair of frames jointly defining a cavity. One of the frames per heater is positioned proximate to the cartridge and includes an input port for receiving a liquid solution of methanol. The other frame per heater is positioned distal to the cartridge and includes an input port for receiving oxygen gas and an output port for exhaust gases. A first fluid diffusion medium is positioned within the methanol frame, and a second fluid diffusion medium is positioned within the oxygen frame. Sandwiched between the two diffusion media are a pervaporation membrane facing the first diffusion medium and a porous metal catalyst facing the second diffusion medium. Methanol in liquid form is supplied to the pervaporation membrane, which then transports the methanol in vapor form to the catalyst, where combustion occurs. Heat from the combustion reaction is then conducted through the heater to the cartridge containing the infusion fluid.
Abstract translation: 加热和加热装置的方法 根据一个实施例,加热装置被设计用于加温输液,并且包括位于围绕包含输注液体的药筒的一对催化加热器。 每个催化加热器包括共同限定空腔的一对框架。 每个加热器的框架中的一个定位成靠近墨盒,并且包括用于接收甲醇液体溶液的输入端口。 每个加热器的另一个框架位于盒的远侧,并且包括用于接收氧气的输入端口和用于废气的输出端口。 第一流体扩散介质位于甲醇框架内,第二流体扩散介质位于氧气框架内。 在两个扩散介质之间夹有面向第一扩散介质的渗透蒸发膜和面向第二扩散介质的多孔金属催化剂。 将液体形式的甲醇供应到渗透蒸发膜,然后将蒸气形式的甲醇输送到发生燃烧的催化剂中。 然后将来自燃烧反应的热量通过加热器传导到含有输注流体的药筒。
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14.
公开(公告)号:US07854817B2
公开(公告)日:2010-12-21
申请号:US12129175
申请日:2008-05-29
Applicant: Craig Thompson
Inventor: Craig Thompson
IPC: B29C65/48
CPC classification number: F16B11/006 , C09J5/00 , C09J7/10 , C09J2201/618 , Y10T29/53996 , Y10T156/1002 , Y10T156/1062
Abstract: Herein are disclosed methods and assemblies for mounting an article to a surface by a double-faced adhesive. At least one spacer is used that is deflectable upon the application of sufficient force. When in a first, undeflected condition, the spacer provides sufficient space between the mounting surface and the double-faced adhesive such that the double-faced adhesive does not contact the mounting surface, thus the position of the article can be adjusted. When in a second, deflected condition, the spacer allows the double-faced adhesive to contact the mounting surface such that a bond can be established between the double-faced adhesive and the mounting surface.
Abstract translation: 这里公开了通过双面粘合剂将制品安装到表面上的公开的方法和组件。 使用至少一个在施加足够的力时可偏转的间隔物。 当处于第一未偏转状态时,间隔件在安装表面和双面粘合剂之间提供足够的空间,使得双面粘合剂不接触安装表面,因此可以调节制品的位置。 当处于第二个偏转状态时,间隔件允许双面粘合剂接触安装表面,使得可以在双面粘合剂和安装表面之间建立粘结。
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公开(公告)号:US20100133889A1
公开(公告)日:2010-06-03
申请号:US12611346
申请日:2009-11-03
Applicant: Tavis Lutzka , Stephen Bruck , Stanley D. Pacolt , Mark L. Gleason , David L. Quittschreiber , Jason Hamilton , Craig Thompson
Inventor: Tavis Lutzka , Stephen Bruck , Stanley D. Pacolt , Mark L. Gleason , David L. Quittschreiber , Jason Hamilton , Craig Thompson
CPC classification number: B60N2/36 , B60N2/3009 , B60N2/844 , B60N2/859
Abstract: A pivoting headrest assembly including a bracket supported upon a seatback frame. A headrest support secures a bun and is pivotally secured to the bracket in a forward biased direction. A sector is pivotally secured to the bracket and to which is attached the headrest support. A release catch is pivotally supported at a further location of the bracket and is biased in a first upward direction so that the catch abuts a projecting pin associated with the sector in an upright design position established by the headrest support. A cable is secured to a support fixed to a side of the bracket and engages the catch at a location offset from its pivot axis relative to the bracket. Upon displacement of the cable, the catch is actuated out of engagement with the sector, resulting in the headrest support pivoting relative to the seatback.
Abstract translation: 一种旋转头枕组件,包括支撑在座椅靠背框架上的支架。 头枕支撑件固定un子并以正向偏置的方向枢转地固定到支架上。 扇形部枢转地固定到支架上,并且头枕支撑件附接到该部分。 释放卡爪枢转地支撑在支架的另一位置处并且被向第一向上的方向偏置,使得卡扣以与头部支撑件所建立的直立设计位置邻接与扇形部相关联的突出销。 电缆被固定到固定到支架侧面的支撑件上,并将锁扣接合在相对于支架偏离其枢转轴线的位置处。 在电缆移位时,卡扣被驱动离开与扇形部分的接合,导致头枕支撑件相对于座椅靠背枢转。
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公开(公告)号:USD592434S1
公开(公告)日:2009-05-19
申请号:US29284147
申请日:2007-08-31
Applicant: Craig Thompson , Peter J. Nowbould , Ivana Babic
Designer: Craig Thompson , Peter J. Nowbould , Ivana Babic
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公开(公告)号:USD579255S1
公开(公告)日:2008-10-28
申请号:US29296614
申请日:2007-10-24
Applicant: Craig Thompson , Byron E. Trotter , John M. Pilgrim , Ivana Babic , Gabriel F. Zangari , Peter J. Newbould , Michele Cestone
Designer: Craig Thompson , Byron E. Trotter , John M. Pilgrim , Ivana Babic , Gabriel F. Zangari , Peter J. Newbould , Michele Cestone
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公开(公告)号:USD568081S1
公开(公告)日:2008-05-06
申请号:US29276118
申请日:2007-01-16
Applicant: Craig Thompson , Christopher J Miller , Peter J. Newbould
Designer: Craig Thompson , Christopher J Miller , Peter J. Newbould
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公开(公告)号:USD554407S1
公开(公告)日:2007-11-06
申请号:US29276115
申请日:2007-01-16
Applicant: Craig Thompson , Christopher J. Miller , Peter J. Newbould
Designer: Craig Thompson , Christopher J. Miller , Peter J. Newbould
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公开(公告)号:US20060219748A1
公开(公告)日:2006-10-05
申请号:US11098291
申请日:2005-04-04
Applicant: Craig Thompson , Dennis Crawford , Peter Newbould , Sigurdur Thorsteinsson , Steven Turch
Inventor: Craig Thompson , Dennis Crawford , Peter Newbould , Sigurdur Thorsteinsson , Steven Turch
IPC: B26F3/02
CPC classification number: B65H35/0026 , Y10T156/1795 , Y10T156/18 , Y10T225/20 , Y10T225/211 , Y10T225/282
Abstract: The inventive tape dispenser includes a cover and a base. The cover includes a forward section, a saddle, a rounded back section, and first and second sidewalls extending downwardly from the forward section and saddle. The forward section of the cover includes a first end from which a means for cutting extends. The base includes a semicircular tape holding portion having a first side opposite a second side, a mounting surface and an inner surface. The inner surface of the base includes a means for gripping the dispenser. The base also includes an arm, a land area extending at an angle from the arm and an edge extending an angle from the land area. The edge is disposed substantially parallel to and proximate to the second sidewall of the cover.
Abstract translation: 本发明的胶带分配器包括盖和底座。 盖包括前部,鞍座,圆形后部,以及从前部和鞍座向下延伸的第一和第二侧壁。 盖的前部包括第一端,切割装置从该第一端延伸。 底座包括具有与第二侧相对的第一侧,安装表面和内表面的半圆形带保持部分。 底座的内表面包括用于夹紧分配器的装置。 基座还包括臂,与臂成一定角度延伸的陆部区域和从陆地区域延伸一角度的边缘。 边缘基本上平行于盖子的第二侧壁并且靠近盖子的第二侧壁设置。
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