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公开(公告)号：US09011651B2
公开(公告)日：2015-04-21
申请号：US12963857
申请日：2010-12-09
申请人： Elias Greenbaum
发明人： Elias Greenbaum
IPC分类号： C25B11/00 , C25B1/02 , C25B1/04 , C01B13/02 , C25B1/34 , C25B9/06 , C25B9/08 , C25B11/02 , C10G45/02 , C10G49/00 , C10G2/00
CPC分类号： C25B1/04 , C01B13/0207 , C10G2/32 , C10G45/02 , C10G49/00 , C25B1/34 , C25B9/06 , C25B9/08 , C25B11/02 , Y02E60/366 , Y02P20/133 , Y02P20/134
摘要： An apparatus for the electrolytic splitting of water into hydrogen and/or oxygen, the apparatus comprising: (i) at least one lithographically-patternable substrate having a surface; (ii) a plurality of microscaled catalytic electrodes embedded in said surface; (iii) at least one counter electrode in proximity to but not on said surface; (iv) means for collecting evolved hydrogen and/or oxygen gas; (v) electrical powering means for applying a voltage across said plurality of microscaled catalytic electrodes and said at least one counter electrode; and (vi) a container for holding an aqueous electrolyte and housing said plurality of microscaled catalytic electrodes and said at least one counter electrode. Electrolytic processes using the above electrolytic apparatus or functional mimics thereof are also described.
摘要翻译： 一种用于将水电解成氢和/或氧的装置，所述装置包括：（i）至少一个具有表面的可光滑图案化的基底; （ii）嵌入所述表面中的多个微型催化电极; （iii）在所述表面附近但不在所述表面上的至少一个对电极; （iv）用于收集放出的氢气和/或氧气的装置; （v）用于在所述多个微量催化电极和所述至少一个对电极之间施加电压的电力供电装置; 和（vi）用于容纳含水电解质并容纳所述多个微细化的催化电极和所述至少一个对电极的容器。 还描述了使用上述电解装置的电解方法或其功能模拟物。
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公开(公告)号：US08476062B2
公开(公告)日：2013-07-02
申请号：US13431664
申请日：2012-03-27
CPC分类号： C12Q1/025
摘要： A system for biosensor-based detection of toxins includes providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a time-dependent biosensor signal from the biosensor in the gas or liquid medium to be monitored or analyzed for the presence of one or more toxins selected from chemical, biological or radiological agents. The time-dependent biosensor signal is processed to obtain a plurality of feature vectors using at least one of amplitude statistics and a time-frequency analysis. At least one parameter relating to toxicity of the gas or liquid medium is then determined from the feature vectors based on reference to the control signal.
摘要翻译： 用于基于生物传感器的毒素检测系统包括在气体或液体介质中提供由生物传感器产生的至少一个与时间有关的控制信号，并从待监测的气体或液体介质中的生物传感器获得时间依赖的生物传感器信号 或分析一种或多种选自化学，生物或放射剂的毒素的存在。 处理时间依赖的生物传感器信号以使用幅度统计和时间 - 频率分析中的至少一个来获得多个特征向量。 然后，基于对控制信号的参考，从特征向量确定与气体或液体介质的毒性有关的至少一个参数。
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公开(公告)号：US20070136834A1
公开(公告)日：2007-06-14
申请号：US11302844
申请日：2005-12-14
申请人： Elias Greenbaum , Miguel Rodriguez
发明人： Elias Greenbaum , Miguel Rodriguez
CPC分类号： G06F19/00 , C12Q1/02 , C12Q1/22 , G01N2333/405
摘要： A method of biosensor-based detection of toxins includes the steps of providing a fluid to be analyzed having a plurality of photosynthetic organisms therein, wherein chemical, biological or radiological agents alter a nominal photosynthetic activity of the photosynthetic organisms. At a first time a measured photosynthetic activity curve is obtained from the photosynthetic organisms. The measured curve is automatically compared to a reference photosynthetic activity curve to determine differences therebetween. The presence of the chemical, biological or radiological agents, or precursors thereof, are then identified if present in the fluid using the differences.
摘要翻译： 一种基于生物传感器的毒素检测方法包括以下步骤：提供待分析的流体，其中具有多个光合生物，其中化学，生物或放射剂改变光合生物的标称光合活性。 第一次从光合生物获得测量的光合活性曲线。 测量曲线自动与参考光合活性曲线进行比较，以确定它们之间的差异。 然后如果使用差异存在于流体中，则鉴定化学，生物或放射性物质或其前体的存在。
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公开(公告)号：US20050084419A1
公开(公告)日：2005-04-21
申请号：US10689316
申请日：2003-10-20
申请人： David Hill , Miguel Rodriquez , Elias Greenbaum
发明人： David Hill , Miguel Rodriquez , Elias Greenbaum
CPC分类号： G01N1/14 , G01N33/1886 , G01N35/1095 , G01N2001/022 , G01N2333/405 , G01N2520/00 , Y10T436/117497
摘要： An automatic, self-contained device for detecting toxic agents in a water supply includes an analyzer for detecting at least one toxic agent in a water sample, introducing means for introducing a water sample into the analyzer and discharging the water sample from the analyzer, holding means for holding a water sample for a pre-selected period of time before the water sample is introduced into the analyzer, and an electronics package that analyzes raw data from the analyzer and emits a signal indicating the presence of at least one toxic agent in the water sample.
摘要翻译： 一种用于检测供水中的有毒物质的自动独立装置，包括用于检测水样中的至少一种毒物的分析装置，用于将水样引入分析器的引入装置， 用于在将水样品引入分析仪之前将预先选定的时间段保持水样的装置，以及分析来自分析器的原始数据并发出指示至少一种有毒剂存在的信号的电子装置 水样。
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公开(公告)号：US20050084418A1
公开(公告)日：2005-04-21
申请号：US10689261
申请日：2003-10-20
申请人： David Hill , Miguel Rodriquez , Elias Greenbaum , James Klett
发明人： David Hill , Miguel Rodriquez , Elias Greenbaum , James Klett
CPC分类号： B63B22/24 , B63B2035/4453
摘要： A freeze resistant buoy system includes a tail-tube buoy having a thermally insulated section disposed predominantly above a waterline, and a thermo-siphon disposed predominantly below the waterline.
摘要翻译： 防冻浮标系统包括具有主要位于水线以上的绝热部分的尾管浮标和主要位于水线下方的热虹吸管。
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公开(公告)号：US06231983B1
公开(公告)日：2001-05-15
申请号：US09181047
申请日：1998-10-27
申请人： Ida Lee , James W. Lee , Elias Greenbaum
发明人： Ida Lee , James W. Lee , Elias Greenbaum
IPC分类号： B32B1504
CPC分类号： H01L51/0595 , B82Y10/00 , Y10S428/91 , Y10T428/31504 , Y10T428/31678
摘要： Molecular devices using functional Photosystem I reaction centers are prepared on flat derivatized substrate surfaces. The nature and extent of orientation are controlled by chemical modification of the surface derivative. The surface of the substrate is chemically modified such that the Photosystem I reaction centers may be immobilized in a desired orientation. Preferably, a sulfur-organic compound is used to chemically modify the surface of the substrate. Depending on the type of chemical modification, the orientation of the reaction centers may be parallel to the surface, perpendicular to the surface in the “up” position, or perpendicular to the surface in the “down” position. The different orientations provide different electrical characteristics to the device.
摘要翻译： 使用功能性光系统I反应中心的分子装置在平坦衍生的基底表面上制备。 取向的性质和程度由表面衍生物的化学改性控制。 衬底的表面被化学修饰，使得光系统I反应中心可以以期望的取向固定。 优选地，使用硫 - 有机化合物来化学改性基材的表面。 取决于化学改性的类型，反应中心的取向可以平行于垂直于“向上”位置的表面或垂直于“向下”位置的表面的表面。 不同的方向为装置提供不同的电气特性。
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公开(公告)号：US08209024B2
公开(公告)日：2012-06-26
申请号：US12523990
申请日：2008-01-22
申请人： Elias Greenbaum , Mark S. Humayun
发明人： Elias Greenbaum , Mark S. Humayun
IPC分类号： A61N1/00
摘要： The present invention relates to the treatment of ischemic diseases, and more particularly, to treatment of diabetic retinopathy and ischemia of the retinal and choroidal tissues. The treatment, which will work in vitrectomized eyes as well as non-vitrectomized eyes, is based on selective and fractional electrolysis of the vitreous humor to produce oxygen and optionally active chlorine while simultaneously controlling pH. Oxygen or active chlorine can suppress or reverse the onset of diabetic retinopathy, other retinovascular diseases, and choroidal neovascularization.
摘要翻译： 本发明涉及治疗缺血性疾病，更具体地涉及治疗糖尿病视网膜病变和视网膜和脉络膜组织缺血。 在玻璃体切割的眼睛以及非玻璃体切割的眼睛中工作的治疗是基于玻璃体液的选择和分数电解以产生氧气和任选的活性氯，同时控制pH。 氧或活性氯可以抑制或逆转糖尿病性视网膜病变，其他视网膜血管疾病和脉络膜新血管形成。
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公开(公告)号：US20120149789A1
公开(公告)日：2012-06-14
申请号：US12963857
申请日：2010-12-09
申请人： Elias Greenbaum
发明人： Elias Greenbaum
IPC分类号： C07C27/00 , C25B9/04 , C25B1/10 , C01C1/04 , C25B1/34 , C10G45/00 , C07C5/02 , C25B9/00 , C25B1/04
CPC分类号： C25B1/04 , C01B13/0207 , C10G2/32 , C10G45/02 , C10G49/00 , C25B1/34 , C25B9/06 , C25B9/08 , C25B11/02 , Y02E60/366 , Y02P20/133 , Y02P20/134
摘要： An apparatus for the electrolytic splitting of water into hydrogen and/or oxygen, the apparatus comprising: (i) at least one lithographically-patternable substrate having a surface; (ii) a plurality of microscaled catalytic electrodes embedded in said surface; (iii) at least one counter electrode in proximity to but not on said surface; (iv) means for collecting evolved hydrogen and/or oxygen gas; (v) electrical powering means for applying a voltage across said plurality of microscaled catalytic electrodes and said at least one counter electrode; and (vi) a container for holding an aqueous electrolyte and housing said plurality of microscaled catalytic electrodes and said at least one counter electrode. Electrolytic processes using the above electrolytic apparatus or functional mimics thereof are also described.
摘要翻译： 一种用于将水电解成氢和/或氧的装置，所述装置包括：（i）至少一个具有表面的可光滑图案化的基底; （ii）嵌入所述表面中的多个微型催化电极; （iii）在所述表面附近但不在所述表面上的至少一个对电极; （iv）用于收集放出的氢气和/或氧气的装置; （v）用于在所述多个微量催化电极和所述至少一个对电极之间施加电压的电力供电装置; 和（vi）用于容纳含水电解质并容纳所述多个微细化的催化电极和所述至少一个对电极的容器。 还描述了使用上述电解设备的电解方法或其功能模拟物。
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公开(公告)号：US20100168646A1
公开(公告)日：2010-07-01
申请号：US12523990
申请日：2008-01-22
申请人： Elias Greenbaum , Mark S. Humayun , Yu-Chong Tai
发明人： Elias Greenbaum , Mark S. Humayun , Yu-Chong Tai
IPC分类号： A61N1/18
摘要： The present invention relates to the treatment of ischemic diseases, and more particularly, to treatment of diabetic retinopathy and ischemia of the retinal and choroidal tissues. The treatment, which will work in vitrectomized eyes as well as non-vitrectomized eyes, is based on selective and fractional electrolysis of the vitreous humor to produce oxygen and optionally active chlorine while simultaneously controlling pH. Oxygen or active chlorine can suppress or reverse the onset of diabetic retinopathy, other retinovascular diseases, and choroidal neovascularization.
摘要翻译： 本发明涉及治疗缺血性疾病，更具体地涉及治疗糖尿病视网膜病变和视网膜和脉络膜组织缺血。 在玻璃体切割的眼睛以及非玻璃体切割的眼睛中工作的治疗是基于玻璃体液的选择和分数电解以产生氧气和任选的活性氯，同时控制pH。 氧或活性氯可以抑制或逆转糖尿病性视网膜病变，其他视网膜血管疾病和脉络膜新血管形成。
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公开(公告)号：US20070259420A1
公开(公告)日：2007-11-08
申请号：US11754556
申请日：2007-05-29
申请人： Elias Greenbaum , Tanya Kuritz , Mark Humayun
发明人： Elias Greenbaum , Tanya Kuritz , Mark Humayun
IPC分类号： C12N5/06
CPC分类号： C07K14/705 , A61K38/00 , A61K41/0071
摘要： Photoreactivity in a cell is modulated by incorporating an isolated optical trigger on the surface or in the membrane of the cell. Exposure of a cell bearing incorporated optical triggers causes the generation of a measurable physiological signal.
摘要翻译： 细胞中的光反应性通过在细胞的表面或细胞膜上并入隔离的光触发来调节。 带有结合光学触发器的细胞的暴露导致产生可测量的生理信号。
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