公开(公告)号：US10982400B2

公开(公告)日：2021-04-20

申请号：US16462600

申请日：2017-03-24

Applicant: Miguel Rodriguez Larreta ,  Luis Maria Chiodo

Inventor： Miguel Rodriguez Larreta ,  Luis Maria Chiodo

IPC: E02B1/00 ,  A01K61/20 ,  A01G33/00 ,  A01K61/00 ,  A01K63/04 ,  C02F1/00 ,  C02F1/38 ,  C02F3/32 ,  C02F103/00 ,  C02F103/42

Abstract: The present invention is a new process for preserving the water of an aquatic body as a supplying source for different human activities such as recreation and amusement, food and ornamentation, by the development of a aquatic space formed by a Open water Lake, a Spa Lake, and a Water Depuration Lake that preserves the water mass by biotransformation and mineralization that allow reducing the concentration of carbon, nitrogen and phosphorous, generating clean and transparent water without the use of large amounts of chemicals and complex filtrate systems.

公开(公告)号：US07258836B2

公开(公告)日：2007-08-21

申请号：US10689261

申请日：2003-10-20

Applicant: David E. Hill ,  Miguel Rodriguez, Jr. ,  Elias Greenbaum ,  James W. Klett

Inventor： David E. Hill ,  Miguel Rodriguez, Jr. ,  Elias Greenbaum ,  James W. Klett

IPC: G01N21/00

CPC classification number: B63B22/24 ,  B63B2035/4453

Abstract: A freeze resistant buoy system includes a tail-tube buoy having a thermally insulated section disposed predominantly above a waterline, and a thermo-siphon disposed predominantly below the waterline.

Abstract translation: 防冻浮标系统包括具有主要位于水线以上的绝热部分的尾管浮标和主要位于水线下方的热虹吸管。

公开(公告)号：US20070105184A1

公开(公告)日：2007-05-10

申请号：US11216282

申请日：2005-08-31

Applicant: Elias Greenbaum ,  Miguel Rodriguez ,  Qi Hairong ,  Xiaoling Wang

Inventor： Elias Greenbaum ,  Miguel Rodriguez ,  Qi Hairong ,  Xiaoling Wang

IPC: C12Q1/02

CPC classification number: C12Q1/025

Abstract: A method of biosensor-based detection of toxins comprises the steps of providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a time-dependent biosensor signal from the biosensor in the gas or liquid medium to be monitored or analyzed for the presence of one or more toxins selected from chemical, biological or radiological agents. The time-dependent biosensor signal is processed to obtain a plurality of feature vectors using at least one of amplitude statistics and a time-frequency analysis. At least one parameter relating to toxicity of the gas or liquid medium is then determined from the feature vectors based on reference to the control signal.

Abstract translation: 一种基于生物传感器的毒素检测方法包括以下步骤：在气体或液体介质中提供由生物传感器产生的至少一个时间依赖的控制信号，并从气体或液体介质中的生物传感器获得时间依赖的生物传感器信号 被监测或分析一种或多种选自化学，生物或放射剂的毒素的存在。 处理时间依赖的生物传感器信号以使用幅度统计和时间 - 频率分析中的至少一个来获得多个特征向量。 然后，基于对控制信号的参考，从特征向量确定与气体或液体介质的毒性有关的至少一个参数。

公开(公告)号：US06495329B1

公开(公告)日：2002-12-17

申请号：US09044154

申请日：1998-03-19

Applicant: Carlos Martinez Alonso ,  José Mario Mellado Garcia ,  Leonor Kremer Baron ,  José Miguel Rodriguez Frade

Inventor： Carlos Martinez Alonso ,  José Mario Mellado Garcia ,  Leonor Kremer Baron ,  José Miguel Rodriguez Frade

IPC: G01N3353

Abstract: The present invention relates to a method for determinating cytokine receptor, especially growth hormone receptor (GHR), activation, by the use of an antibody capable of discriminating between an activated and an inactive cytokine receptor conformation, especially GHR or growth hormone binding protein (GHBP) conformation, the method comprising: contacting the antibody and the cytokine receptor to form a complex, contacting a candidate ligand to the complex, measuring the antibody binding to inactive cytokine receptor and thereby discriminating between an activated and an inactive conformation. The invention also relates to an antibody directed to the hinge spanning subdomains I and II of the growth hormone receptor extracellular region and which is capable of discriminating between an activated and an inactive receptor conformation. The invention also relates to the use of the antibody for e.g. characterization of growth hormone receptor interactions and for screening for compounds stabilising die dimerization of GHR.

公开(公告)号：US11001087B2

公开(公告)日：2021-05-11

申请号：US15464833

申请日：2017-03-21

Applicant: Miguel Rodriguez ,  Eric Cheng

Inventor： Miguel Rodriguez ,  Eric Cheng

IPC: B41J29/38 ,  B41J2/045 ,  G01N33/483 ,  G01N15/14 ,  C12Q3/00 ,  G01N35/10 ,  B01L3/02 ,  G01F25/00

Abstract: A method of depositing single particles onto a target includes loading a particle suspension to a droplet dispenser having a suspension reservoir and a nozzle section, detecting particles in the nozzle section, testing a single particle condition of the droplet dispenser, and determining whether an ejection region of the nozzle section includes one single particle. The method further includes operating the droplet dispenser for dispensing a droplet such that the droplet is dispensed onto the target if the single particle condition is fulfilled, or the droplet is dispensed into a collection reservoir if the single particle condition is not fulfilled. The step of testing the single particle condition further includes determining whether a sedimentation region adjacent to the ejection region is free of particles. A dispenser for performing the method is also provided.

公开(公告)号：US20180236336A1

公开(公告)日：2018-08-23

申请号：US15889165

申请日：2018-02-05

Applicant: Miguel Rodriguez

Inventor： Miguel Rodriguez

IPC: A63B69/00 ,  A63B71/00 ,  G09B19/00

CPC classification number: A63B69/0064 ,  A63B5/16 ,  A63B21/00181 ,  A63B21/285 ,  A63B21/4009 ,  A63B69/0057 ,  A63B71/0054 ,  A63B2225/093 ,  A63B2244/206 ,  G09B19/0038

Abstract: An acrobatic training apparatus for training individuals to perform acrobatic tricks is provided. The apparatus includes a main frame having a first base section having first and second parallel base struts connected by first and second cross member; a platform mounted on the first base section of the main frame; a plurality of elongated vertical members extending vertically upward from the first and second parallel base struts of the first base section; a first upper support member connected between a first pair of elongated vertical support members of the plurality of elongated vertical members; a second upper support member connected between a second pair of elongated vertical support members; a height adjustment mechanism adjustably mounted on the main frame configured to adapt to the height of the user; and a spotting apparatus mounted on the main frame and secured to the height adjustment mechanism.

公开(公告)号：US20160144533A1

公开(公告)日：2016-05-26

申请号：US15010430

申请日：2016-01-29

Applicant: Keith Van Duinen ,  Miguel Rodriguez ,  Alejandro Leon

Inventor： Keith Van Duinen ,  Miguel Rodriguez ,  Alejandro Leon

IPC: B29B13/00 ,  B05C11/10

CPC classification number: B29B13/00 ,  B05C11/1021 ,  B05C11/1042 ,  B29B2013/005 ,  B29C31/06 ,  B29C39/24 ,  B29K2063/00 ,  B29L2011/0075 ,  G02B6/3861

Abstract: A method for dispensing epoxy comprising the step of degassing an epoxy. The method further comprises the step of associating the epoxy with an epoxy injector comprising a dispensing end. The method further comprises the step of a computer receiving data representative of a selected container to receive the epoxy. The method further comprises the step of a computer determining a dispensing rate and a dispensing amount, based on the received data. The method further comprises the step of a computer causing the epoxy injector to dispense the determined dispensing amount of epoxy, via the dispensing end, at the determined dispensing rate. The method further comprises the step of a computer causing a dispensing arm, supporting the dispensing end, to retract the dispensing end while the epoxy injector is dispensing the epoxy. The method further comprises the step of curing the dispensed epoxy.

Abstract translation: 一种用于分配环氧树脂的方法，包括对环氧树脂进行脱气的步骤。 该方法还包括将环氧树脂与包含分配端的环氧树脂注射器相关联的步骤。 该方法还包括计算机接收表示所选容器的数据以接收环氧树脂的步骤。 该方法还包括基于所接收的数据计算机确定分配速率和分配量的步骤。 该方法还包括计算机的步骤，使得环氧注射器以所确定的分配速率经由分配端分配所确定的环氧树脂分配量。 该方法还包括一台计算机，当环氧喷射器分配环氧树脂时，引起支撑分配端的分配臂缩回分配端。 该方法还包括固化分配的环氧树脂的步骤。

公开(公告)号：US20140248560A1

公开(公告)日：2014-09-04

申请号：US14343401

申请日：2012-09-25

Applicant: Martin Edwards ,  Daniel Morris ,  Miguel Rodriguez-Vazquez

Inventor： Martin Edwards ,  Daniel Morris ,  Miguel Rodriguez-Vazquez

IPC: G03G9/08

CPC classification number: G03G9/0819 ,  C08J3/12 ,  C08J3/128 ,  C08J3/16 ,  C08J2333/12 ,  G03G9/0804 ,  G03G9/0812 ,  G03G9/0827 ,  G03G9/0926 ,  G03G9/097 ,  G03G9/09708

Abstract: A process for preparing a particulate solid is described, which comprises the steps of a) aggregating a dispersion comprising the particles i) and ii) and a liquid medium, wherein i) is 25 to 50 parts by weight of non-polymeric particles having an average particle size of from 1 to 10 microns and having a density of no more than 4 g/cm3; and ii) is 50 to 75 parts by weight of polymer particles having an average particle size of from 50 to 150 nm; b) optionally stabilising the aggregated particles; and c) heating the aggregated particles so as to cause particle coalescence.

Abstract translation: 描述了一种制备颗粒状固体的方法，其包括以下步骤：a）将包含颗粒i）和ii）和液体介质的分散体聚集，其中i）为25至50重量份的具有 平均粒度为1〜10微米，密度不大于4克/厘米3; 和ii）50〜75重量份的平均粒径为50〜150nm的聚合物粒子; b）任选地稳定聚集的颗粒; 和c）加热聚集的颗粒以使颗粒聚结。

公开(公告)号：US08812239B2

公开(公告)日：2014-08-19

申请号：US11302844

申请日：2005-12-14

Applicant: Elias Greenbaum ,  Miguel Rodriguez, Jr.

Inventor： Elias Greenbaum ,  Miguel Rodriguez, Jr.

IPC: G01N33/50 ,  G01N33/48 ,  G06F19/00

CPC classification number: G06F19/00 ,  C12Q1/02 ,  C12Q1/22 ,  G01N2333/405

Abstract: A method of biosensor-based detection of toxins includes the steps of providing a fluid to be analyzed having a plurality of photosynthetic organisms therein, wherein chemical, biological or radiological agents alter a nominal photosynthetic activity of the photosynthetic organisms. At a first time a measured photosynthetic activity curve is obtained from the photosynthetic organisms. The measured curve is automatically compared to a reference photosynthetic activity curve to determine differences therebetween. The presence of the chemical, biological or radiological agents, or precursors thereof, are then identified if present in the fluid using the differences.

Abstract translation: 一种基于生物传感器的毒素检测方法包括以下步骤：提供待分析的流体，其中具有多个光合生物，其中化学，生物或放射剂改变光合生物的标称光合活性。 第一次从光合生物获得测量的光合活性曲线。 测量曲线自动与参考光合活性曲线进行比较，以确定它们之间的差异。 然后如果使用差异存在于流体中，则鉴定化学，生物或放射性物质或其前体的存在。

公开(公告)号：US20120238009A1

公开(公告)日：2012-09-20

申请号：US13431664

申请日：2012-03-27

Applicant: Elias Greenbaum ,  Miguel Rodriguez, JR. ,  Hairong Qi ,  Xiaoling Wang

Inventor： Elias Greenbaum ,  Miguel Rodriguez, JR. ,  Hairong Qi ,  Xiaoling Wang

IPC: C12M1/34

CPC classification number: C12Q1/025

Abstract: A system for biosensor-based detection of toxins includes providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a time-dependent biosensor signal from the biosensor in the gas or liquid medium to be monitored or analyzed for the presence of one or more toxins selected from chemical, biological or radiological agents. The time-dependent biosensor signal is processed to obtain a plurality of feature vectors using at least one of amplitude statistics and a time-frequency analysis. At least one parameter relating to toxicity of the gas or liquid medium is then determined from the feature vectors based on reference to the control signal.

Abstract translation: 用于基于生物传感器的毒素检测系统包括在气体或液体介质中提供由生物传感器产生的至少一个与时间有关的控制信号，并从待监测的气体或液体介质中的生物传感器获得时间依赖的生物传感器信号 或分析一种或多种选自化学，生物或放射剂的毒素的存在。 处理时间依赖的生物传感器信号以使用幅度统计和时间 - 频率分析中的至少一个来获得多个特征向量。 然后，基于对控制信号的参考，从特征向量确定与气体或液体介质的毒性有关的至少一个参数。