Abstract:
An external power system, system and method for transcutaneous energy transfer to an implantable medical device having componentry for providing a therapeutic output and a secondary coil operatively coupled to the componentry. The implantable medical device is adapted to implanted at a location in a patient. An external power source has a primary coil contained in a housing. The external power source is capable of providing energy to the implantable medical device when the primary coil of the external power source is placed in proximity of the secondary coil of the implantable medical device. A holder is adapted to be externally positioned with respect to the patient at a spot in proximity of the location of the implantable medical device and secured at the spot. The holder is attachable to the housing after the holder is secured to the patient.
Abstract:
An external device, charge, system and method for an implantable medical device having therapeutic componentry, a secondary coil operatively coupled to the therapeutic componentry and an internal telemetry coil. A primary coil is capable of inductively energizing the secondary coil when externally placed in proximity of the secondary coil. An external telemetry coil is capable of communicating with the internal telemetry coil. Driver circuitry is selectively operatively coupled to the primary coil and to the external telemetry coil. The driver circuitry is switchable between (1) driving the primary coil for inductively energizing the secondary coil and (2) driving the external telemetry coil for communicating with the internal telemetry coil.
Abstract:
In general, the invention is directed to a patient programmer for an implantable medical device. The patient programmer may include one or more of a variety of features that may enhance performance, support mobility and compactness, or promote patient convenience.
Abstract:
In general, the invention is directed to a patient programmer for an implantable medical device. The patient programmer may include one or more of a variety of features that may enhance performance, support mobility and compactness, or promote patient convenience.
Abstract:
A fuel system includes an electronically controllable high pressure fuel pump operable to supply high pressure fuel from a lower pressure fuel source to a high pressure fuel collection chamber having a pressure sensor associated therewith. The fuel collection chamber feeds an electronically controllable valve operable to dispense the high pressure fuel to a fuel distribution unit supplying fuel to a number of fuel injectors. A control computer is provided for controlling the high pressure fuel pump and valve in response to requested fueling, engine speed and fuel pressure provided by the pressure sensor. The control computer is normally operable to drive the fuel pump as a function of fuel pressure and a reference pressure, which is based on requested fueling, and to control the valve as a function of commanded fueling, which is a function of engine speed and a reference speed based on requested fueling, and fuel pressure. In a first limp home mode, the control computer is operable to drive the fuel pump as a function of fuel pressure and commanded fueling if abnormal operation of the high pressure fuel pump is detected. In this mode, the valve is controlled only as a function of fuel pressure. In a second limp home mode, the control computer is operable to drive the fuel pump with a predicted fuel pump command based on the fuel command and engine speed, if abnormal operation of the pressure sensor is detected. In this mode, the valve is controlled as a function of the fuel command and the reference pressure or a default pressure.
Abstract:
Conductimetric assay devices that have both low end and high end sensitivity are described. The geometric shape and/or arrangement of the capture zones make it possible for the assay devices to have both low end and high end sensitivity. Also described is a conductimetric assay device having a pre-capture zone to capture unbound analyte. The assay device overcomes the problem of flooding by the analyte.
Abstract:
The flow cytometer user interface of the preferred embodiment comprises the steps of (1) running the sample and saving all collected data, (2) viewing the raw (or “unmodified”) data, (3) modifying the raw data (e.g., scaling and/or culling the raw data), (4) reviewing and saving the modified settings, and (5) exporting the saved data. Once the sample has been run and all collected data have been saved, the user can repeat the steps of modifying the raw data, saving the modified settings, and exporting the saved data as many times as necessary and/or desirable without the need to run an additional sample.
Abstract:
The present invention relates to a fluid treatment system comprising: an inlet; an outlet; and a fluid treatment zone disposed between the inlet and the outlet. The fluid treatment zone has disposed therein: (i) an elongate first radiation source assembly having a first longitudinal axis, and (ii) an elongate second radiation source assembly having a second longitudinal axis. The first longitudinal axis and the second longitudinal axis are non-parallel to each other and to a direction of fluid flow through the fluid treatment zone. The present fluid treatment system has a number of advantages including: it can treat large volumes of fluid (e.g., wastewater, drinking water or the like); it requires a relatively small “footprint”; it results in a relatively lower coefficient of drag resulting in an improved hydraulic pressure loss/gradient over the length of the fluid treatment system; and it results in relatively lower (or no) forced oscillation of the radiation sources thereby obviating or mitigating of breakage of the radiation source and/or protective sleeve (if present). Other advantages are discussed in the specification.
Abstract:
A system, method and program product for determining parallelism of an ion beam using a refraction method, are disclosed. One embodiment includes determining a first test position of the ion beam while not exposing the ion beam to an acceleration/deceleration electrical field, determining a second test position of the ion beam while exposing the ion beam to an acceleration/deceleration electrical field, and determining the parallelism of the ion beam based on the first test position and the second test position. The acceleration/deceleration electrical field acts to refract the ion beam between the two positions when the beam is not parallel, hence magnifying any non-parallelism. The amount of refraction, or lateral shift, can be used to determine the amount of non-parallelism of the ion beam. An ion implanter system and adjustments of the ion implanter system based on the parallelism determination are also disclosed.
Abstract:
The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.