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公开(公告)号：US10543085B2
公开(公告)日：2020-01-28
申请号：US16007879
申请日：2018-06-13
Applicant: Edwards Lifesciences Corporation
Inventor： Visith Chung , Da-Yu Chang , Brian S. Conklin , Grace Myong Kim , Louis A. Campbell , Donald E. Bobo, Jr. , Myron Howanec, Jr. , David S. Lin , Peng Norasing , Francis M. Tran , Mark Van Nest , Thomas H. Chien , Harvey H. Chen , Isidro L. Guerrero , Derrick Johnson , Paul A. Schmidt
IPC: A61F2/24
Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.
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公开(公告)号：US10130466B2
公开(公告)日：2018-11-20
申请号：US15079854
申请日：2016-03-24
Applicant: Edwards Lifesciences Corporation
Inventor： Louis A. Campbell , Donald E. Bobo, Jr. , Gregory A. Wright , Tak G. Cheung
Abstract: A valved conduit including a bioprosthetic valve, such as a heart valve, and a tubular conduit sealed with a bioresorbable material. The bioprosthetic heart valve includes prosthetic tissue that has been treated such that the tissue may be stored dry for extended periods without degradation of functionality of the valve. The bioprosthetic heart valve may have separate bovine pericardial leaflets or a whole porcine valve. The sealed conduit includes a tubular matrix impregnated with a bioresorbable medium such as gelatin or collagen. The valved conduit is stored dry in packaging in which a desiccant pouch is supplied having a capacity for absorbing moisture within the packaging limited to avoid drying the bioprosthetic tissue out beyond a point where its ability to function in the bioprosthetic heart valve is compromised. The heart valve may be sewn within the sealed conduit or coupled thereto with a snap-fit connection.
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公开(公告)号：US09504570B2
公开(公告)日：2016-11-29
申请号：US14159251
申请日：2014-01-20
Applicant: Edwards Lifesciences Corporation
Inventor： David L. Hauser , Donald E. Bobo, Jr.
CPC classification number: A61F2/2454 , A61F2/2442 , A61F2/2445 , A61F2/246 , A61F2/2478 , A61F2/2487 , A61F2/82 , A61F2002/8483 , A61F2210/0004 , A61F2210/0014 , A61F2220/0016 , A61F2230/0004
Abstract: A device for reshaping the tricuspid valve comprises a stent that is deployed in the right ventricular outflow tract (RVOT) adjacent to the tricuspid valve and expanded to a size sufficient to reduce the annular diameter or size of the tricuspid valve, thereby improving coaptation of the leaflets and reducing regurgitation. Embodiments of the device are deliverable percutaneously.
Abstract translation: 用于重塑三尖瓣的装置包括展开在邻近三尖瓣的右心室流出道（RVOT）中的支架，并且扩张到足以减小三尖瓣的环直径或尺寸的尺寸，从而改善 传单和减少反流。 该装置的实施例可经皮递送。
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公开(公告)号：US20140188221A1
公开(公告)日：2014-07-03
申请号：US14136318
申请日：2013-12-20
Applicant: Edwards Lifesciences Corporation
Inventor： Visith Chung , Da-Yu Chang , Brian S. Conklin , Grace M. Kim , Louis A. Campbell , Donald E. Bobo, Jr. , Myron Howanec , David S. Lin , Peng Norasing , Francis M. Tran , Mark Van Nest , Thomas Y. Chien , Harvey H. Chen , Isidro L. Guerrero , Derrick Johnson , Paul A. Schmidt
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2433 , A61F2/2445 , A61F2210/0004 , A61F2220/0033 , A61F2220/0075 , A61F2250/0004 , A61F2250/001 , A61F2250/006 , A61F2250/0063 , A61F2250/0071 , A61F2310/00011
Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.
Abstract translation: 公开了一种假体心脏瓣膜，其构造成替代原生心脏瓣膜并且具有构造成重新成形为膨胀形式以支撑可膨胀假体心脏瓣膜和/或支撑其中的可扩张假体心脏瓣膜的支撑框架及其使用方法。 假体心脏瓣膜可以被构造成当最初植入时具有大致刚性和/或抗膨胀的构造，以替代天然瓣膜（或其他假体心脏瓣膜），但是当受到向外的力（例如， 由膨胀气球或其他机械膨胀机提供。
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公开(公告)号：US11471275B2
公开(公告)日：2022-10-18
申请号：US16888649
申请日：2020-05-29
Applicant: Edwards Lifesciences Corporation
Inventor： Salvador Marquez , Da-Yu Chang , Cindy Woo , Hao-Chung Yang , Lynn T. Dang , Javier A. Sanguinetti , Alexander H. Siemons , Yaron Keidar , Virginia Qi Lin , Brian S. Conklin , Donald E. Bobo, Jr.
Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.
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Patent Agency Ranking
公开(公告)号：US20180221016A1
公开(公告)日：2018-08-09
申请号：US15944337
申请日：2018-04-03
Applicant: Edwards Lifesciences Corporation
Inventor： Brian S. Conklin , Louis A. Campbell , Salvador Marquez , Donald E. Bobo, Jr.
CPC classification number: A61B17/0487 , A61B17/0401 , A61B2017/0404 , A61B2017/0409 , A61B2017/0414 , A61B2017/0416 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61F2/24 , A61F2/2409 , A61F2/2442
Abstract: Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without using knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.
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公开(公告)号：US09375310B2
公开(公告)日：2016-06-28
申请号：US14136318
申请日：2013-12-20
Applicant: Edwards Lifesciences Corporation
Inventor： Visith Chung , Da-Yu Chang , Brian S. Conklin , Grace M. Kim , Louis A. Campbell , Donald E. Bobo, Jr. , Myron Howanec , David S. Lin , Peng Norasing , Francis M. Tran , Mark Van Nest , Thomas Y. Chien , Harvey H. Chen , Isidro L. Guerrero , Derrick Johnson , Paul A. Schmidt
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2433 , A61F2/2445 , A61F2210/0004 , A61F2220/0033 , A61F2220/0075 , A61F2250/0004 , A61F2250/001 , A61F2250/006 , A61F2250/0063 , A61F2250/0071 , A61F2310/00011
Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.
Abstract translation: 公开了一种假体心脏瓣膜，其构造成替代原生心脏瓣膜并且具有构造成重新成形为膨胀形式以支撑可膨胀假体心脏瓣膜和/或支撑其中的可扩张假体心脏瓣膜的支撑框架及其使用方法。 假体心脏瓣膜可以被构造成当最初植入时具有大致刚性和/或抗膨胀的构造，以替代天然瓣膜（或其他假体心脏瓣膜），但是当受到向外的力（例如， 由膨胀气球或其他机械膨胀机提供。
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公开(公告)号：US09364322B2
公开(公告)日：2016-06-14
申请号：US14137501
申请日：2013-12-20
Applicant: Edwards Lifesciences Corporation
Inventor： Brian S. Conklin , Louis A. Campbell , Donald E. Bobo, Jr. , Steven M. Ford , Derrick Johnson
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2433 , A61F2/2445 , A61F2210/0004 , A61F2220/0033 , A61F2220/0075 , A61F2250/0004 , A61F2250/001 , A61F2250/006 , A61F2250/0063 , A61F2250/0071 , A61F2310/00011
Abstract: Disclosed herein is a prosthetic heart valve, and associated methods therefore, configured to replace a native heart valve, and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein. The prosthetic heart valve is configured to have an expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.
Abstract translation: 本文公开了一种假体心脏瓣膜，因此，相关联的方法被配置为替代天然心脏瓣膜，并且具有构造成重新成形为膨胀形式的支撑框架，以便在其中容纳和/或支撑可扩张的假体心脏瓣膜。 假体心脏瓣膜被配置为当最初植入时具有抗膨胀构造以替代天然瓣膜（或其他假体心脏瓣膜），但是当受到向外的力（例如由扩张气球 或其他机械膨胀机。
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公开(公告)号：US20130282028A1
公开(公告)日：2013-10-24
申请号：US13920983
申请日：2013-06-18
Applicant: Edwards Lifesciences Corporation
Inventor： Brian S. Conklin , Louis A. Campbell , Salvador Marquez , Donald E. Bobo, Jr.
IPC: A61B17/04
CPC classification number: A61B17/0487 , A61B17/0401 , A61B2017/0404 , A61B2017/0409 , A61B2017/0414 , A61B2017/0416 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61F2/24 , A61F2/2409 , A61F2/2442
Abstract: Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.
Abstract translation: 用于固定假体（例如心脏瓣膜或带有缝线和瓣环的瓣环成形术环）的缝合线锁定件提高了植入的容易性。 夹具具有相对的夹具半部，该半部由通向一侧的狭槽分开，并被诸如一个或多个C形夹弹簧的偏置构件包围。 缝合线横向穿过狭槽，狭槽由位于夹子半部之间的保持构件保持打开。 锁定夹具沿着缝合线滑动到适当位置，调节缝合线的张力，并且移除保持构件以允许偏置构件将缝合线夹在夹具半部之间。 用于传送和展开锁定夹具的输送工具在堆叠中的输送管内包含多个夹具，并且为了安全而将其粘合在一起并具有公共保持构件。 该工具在一侧具有用于进入缝合线的纵向通道。
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公开(公告)号：US12226311B2
公开(公告)日：2025-02-18
申请号：US18168514
申请日：2023-02-13
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Visith Chung , Da-Yu Chang , Brian S. Conklin , Grace Myong Kim , Louis A. Campbell , Donald E. Bobo, Jr. , Myron Howanec, Jr. , David S. Lin , Peng Norasing , Francis M. Tran , Mark Van Nest , Thomas Chien , Harvey H. Chen , Isidro L. Guerrero , Derrick Johnson , Paul A. Schmidt , Cindy Woo
IPC: A61F2/24
Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.
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