公开(公告)号：US10232564B2

公开(公告)日：2019-03-19

申请号：US15140387

申请日：2016-04-27

Applicant: Edwards Lifesciences Corporation

Inventor： Itai Pelled ,  Elena Sherman ,  Eran Goldberg ,  Kevin D. Rupp ,  Noam Nir

IPC: A61F2/24 ,  B29C65/00

Abstract: The present disclosure relates to laminated sealing members for prosthetic valves and methods of making the same. In a representative embodiment, an implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration comprises an annular frame having an inflow end and an outflow end, a leaflet structure positioned within the frame and secured thereto, and a laminate sealing member comprising an encapsulating material. The laminate sealing member has a main portion that encapsulates at least a portion of the frame and an end portion extending from the inflow end of the frame, and the end portion of the laminate sealing member is folded to form a cuff adjacent the inflow end of the frame and secured to the main portion of the laminate sealing member.

公开(公告)号：US20250010030A1

公开(公告)日：2025-01-09

申请号：US18894212

申请日：2024-09-24

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Eran Goldberg ,  Liron Tayeb ,  David Maimon

IPC: A61M25/00 ,  A61F2/24 ,  A61F2/962

Abstract: Disclosed herein are reinforced expandable introducer sheaths and methods of using the same. The sheaths minimize trauma to the patient's vasculature by including a reinforcing member to improve the push force of the sheath while reducing the chances of kinking during delivery of a prosthetic device. The sheath can include a plurality of expandable rings aligned along the longitudinal axis of the sheath and coupled together to form an elongated tubular structure. The sheath can also include a plurality of radial members circumferentially arranged to form a tubular support structure. The radial members slidingly interconnected around the circumference of the tubular structure to facilitate radial expansion of the sheath.

公开(公告)号：US20240335310A1

公开(公告)日：2024-10-10

申请号：US18747761

申请日：2024-06-19

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Eran Goldberg ,  Noa Axelrod Manela ,  Yair A. Neumann ,  Boaz Manash ,  David Maimon ,  Eyal Leiba ,  Ralph Schneider ,  Liron Tayeb

IPC: A61F2/966 ,  A61F2/24 ,  A61F2/95 ,  A61F2/958 ,  A61F2/962 ,  A61M25/00 ,  A61M29/00 ,  B29D23/00 ,  B29K105/08

CPC classification number: A61F2/966 ,  A61F2/2436 ,  A61F2/9526 ,  A61M25/0012 ,  A61M25/0023 ,  B29D23/00 ,  A61F2/9517 ,  A61F2/9522 ,  A61F2002/9583 ,  A61F2002/9623 ,  A61F2002/9665 ,  A61F2250/001 ,  A61M2025/0024 ,  A61M25/0045 ,  A61M25/005 ,  A61M25/0074 ,  A61M29/00 ,  A61M2205/0216 ,  B29K2105/0827

Abstract: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.

公开(公告)号：US11883288B2

公开(公告)日：2024-01-30

申请号：US17113268

申请日：2020-12-07

Applicant: Edwards Lifesciences Corporation

Inventor： David Maimon ,  Eran Goldberg ,  Liron Tayeb

IPC: A61F2/24 ,  A61M25/00 ,  A61M25/06

CPC classification number: A61F2/2436 ,  A61M25/0023 ,  A61M25/0662 ,  A61M25/005 ,  A61M25/0045 ,  A61M2025/0024 ,  A61M2205/0216 ,  A61M2205/0266

Abstract: The expandable sheath and methods of use disclosed herein are used to deliver a prosthetic device through a patient's vasculature. The sheath is constructed to be expandable in the circumferential direction, while maintaining sufficient stiffness in the longitudinal direction to withstand pushing and resist kinking. The sheath includes a plurality of curved arms extending outwardly from a longitudinally extending spine. The curved arms move away from the longitudinal axis of the sheath when pushed radially outwardly by a passing prosthetic device, and move back toward the longitudinal axis once the prosthetic device has passed.

公开(公告)号：US20230264028A1

公开(公告)日：2023-08-24

申请号：US18141889

申请日：2023-05-01

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Eran Goldberg ,  Oren Cohen

IPC: A61N1/362 ,  A61N1/05

CPC classification number: A61N1/362 ,  A61N1/0565

Abstract: This disclosure is directed to assemblies, apparatuses, and methods for electrically stimulating the body. In one example, a medical apparatus comprises a handle comprising an electrical connection assembly that is configured to establish an electrical connection between a guidewire and an electrode of an external electrical stimulation generator and that is configured to maintain this electrical connection when the guidewire moves longitudinally relative to the handle, or vice versa. The guidewire may be configured to electrically contact tissue of a patient to deliver electrical stimulation to the tissue. In some examples, the medical apparatus may be included in a medical assembly comprising an introducer device that is configured to facilitate subcutaneous insertion of the medical apparatus. The introducer device may be configured to be electrically connected to electrical stimulation generator and may be configured to electrically contact tissue of the patient.

公开(公告)号：US20230200987A1

公开(公告)日：2023-06-29

申请号：US18171258

申请日：2023-02-17

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Eran Goldberg

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2220/0033

Abstract: Embodiments of an implantable frame are disclosed. The frame can have a plurality of struts interconnected to each other to form a mesh structure that is radially expandable and compressible. The frame can have a connecting post extending from an end of the frame. The connecting post can have a body portion and a head portion affixed to an end of the body portion. The head portion can have a first edge extending outwardly of the body portion. The first edge can have a substantially flat portion that is substantially perpendicular to the body portion.

公开(公告)号：US20230017645A1

公开(公告)日：2023-01-19

申请号：US17956729

申请日：2022-09-29

Applicant: Edwards Lifesciences Corporation

Inventor： Jeong Soo Lee ,  Ilan Tamir ,  Eran Goldberg

IPC: A61M25/00 ,  A61M25/06 ,  A61F2/24

Abstract: Disclosed is an expandable sheath that can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. The disclosed sheaths can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Also disclosed is a sheath having inner and outer layers, where a folded portion of the inner layer extends through a slit in the outer layer, and a portion of the outer layer overlaps the folded portion of the inner layer and where a first polymer is disposed between the outer layer and the folded portion of the inner layer.

公开(公告)号：US20220362016A1

公开(公告)日：2022-11-17

申请号：US17816955

申请日：2022-08-02

Applicant: Edwards Lifesciences Corporation

Inventor： Eran Goldberg

IPC: A61F2/24 ,  A61M29/02

Abstract: Devices, systems, and methods may be used for dilating implants utilizing dilation devices. An implant deployment system may include an inflatable body having a central body configured to press an inner surface of the implant to dilate the implant and having a profile that decreases in diameter along a length of the central body. An inflatable body may include a plurality of segments with varying expansion characteristics.

公开(公告)号：US20220257128A1

公开(公告)日：2022-08-18

申请号：US17733614

申请日：2022-04-29

Applicant: Edwards Lifesciences Corporation

Inventor： Eran Goldberg ,  Tamir S. Levi ,  David Maimon ,  Oren Cohen ,  Martyn Rhys Thomas ,  Tomer Saar ,  Elazar Levi Schwarcz

IPC: A61B5/0215 ,  A61F2/24

Abstract: The present invention relates to devices and methods for measuring physiological parameters, such as flow, pressure, temperature, electric conductivity and/or visual indication of thrombus formation or deposits accumulations, prior to, during and/or after prosthetic heart valve implantation procedures.

公开(公告)号：US20220234306A1

公开(公告)日：2022-07-28

申请号：US17719262

申请日：2022-04-12

Applicant: Edwards Lifesciences Corporation

Inventor： Itai Pelled ,  Elena Sherman ,  Eran Goldberg ,  Kevin D. Rupp ,  Noam Nir

IPC: B29C65/00 ,  A61F2/24

Abstract: A prosthetic heart valve has a radially expandable and collapsible annular frame, the frame having an inflow end and an outflow end and defining a longitudinal axis along a lumen of the prosthetic heart valve when it is in the expanded configuration. A leaflet structure is positioned within the frame and secured thereto. The prosthetic heart valve also has a laminate sealing member including a plurality of layers heat-bonded together to encapsulate at least a portion of the frame. The laminate sealing member extends along the longitudinal axis in an upstream direction and doubles back toward the outflow end of the frame at a fold line to form a cuff, and an edge portion of the laminate sealing member is secured to a main portion of the laminate sealing member downstream of the fold line such that the cuff forms an inflow end of the laminate sealing member.