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公开(公告)号：US20250082427A1
公开(公告)日：2025-03-13
申请号：US18957497
申请日：2024-11-22
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Ralph Schneider , Amir Yousef Sajjadi , Yuval Kasher
Abstract: Systems and devices for accessing an inner space between two layers of tissues are provided. A system can include a helical coil within a catheter delivery system. The helical coil can be delivered to the treatment site at which point it can be turned to penetrate and traverse tissue to reach an inner space. The system can further comprise a gas supply system for providing gas to help displace one or both tissue layers to create more access space within the inner space. A tool, prosthetic, or other device can be transferred via the catheter system into the inner space to perform a procedure therein.
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公开(公告)号：US12102310B2
公开(公告)日：2024-10-01
申请号：US17677910
申请日：2022-02-22
Applicant: Edwards Lifesciences Corporation
Inventor： Stanton J. Rowe , Ming H. Wu , Jinny Lee , Ralph Schneider , Sergio Delgado , Ilan Tamir
CPC classification number: A61B17/0218 , A61B17/0057 , A61F2/2427 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00601 , A61B2017/00606 , A61B2017/00623 , A61B2017/00632 , A61B2017/0225 , A61B2017/0237
Abstract: A septal closure and port device for implantation in the atrial septum of a patient's heart includes an expandable frame with a central portion defining a lumen, and first and second opposing end portions. The frame can expand and contract between a compressed, tubular configuration for delivery through the patient's vasculature and an expanded configuration in which the first and second end portions extend radially outwardly from the opposite ends of the central portion. The device can also have a valve member supported on the frame and positioned to block at least the flow of blood from the left atrium to the right atrium through the lumen of the frame. The valve member permits a medical instrument to be inserted through the lumen and into the left atrium, for performing a subsequent medical procedure in the left side of the heart.
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公开(公告)号：US10973638B2
公开(公告)日：2021-04-13
申请号：US15619220
申请日：2017-06-09
Applicant: Edwards Lifesciences Corporation
Inventor： Lauren R. Freschauf , Ralph Schneider
IPC: A61F2/24 , A61B17/08 , A61B17/122 , A61B17/00
Abstract: Embodiments of a leaflet clip device and method of reducing regurgitation through a native heart valve are disclosed. A leaflet clip device can include an elongated clipping member having a first end portion and a second end portion and a tensioning mechanism coupled to the clipping member. The leaflet clip device can further include one or more tensioning members disposed within a lumen of the clipping member, wherein the one or more tensioning members are operatively connected to the tensioning mechanism to transform the clipping member from a delivery configuration to an implantation configuration.
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公开(公告)号：USRE47209E1
公开(公告)日：2019-01-22
申请号：US15499611
申请日：2017-04-27
Applicant: Edwards Lifesciences Corporation
Inventor： Mohammad Jafari , Ming H. Wu , Hengchu Cao , Ralph Schneider , Manouchehr A. Miraki
IPC: A61B17/04 , A61B17/064
Abstract: Disclosed herein are exemplary embodiments of suture securement devices that replace the need to tie knots in sutures. Some embodiments comprise an annular outer body and one or more suture engagement tabs extending inwardly from the outer body. The devices can comprise a superelastic and/or shape-memory material and have a generally in-plane initial configuration. The suture engagement portions are deformable out-of-plane to an active configuration with the outer body compressed and the tabs interlocked with each other. The device can be heat-set in the deformed configuration. The interlocked tabs exert a pinching force on sutures passing between them that restricts the sutures from sliding through the opening in one longitudinal direction.
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公开(公告)号：US20190000615A1
公开(公告)日：2019-01-03
申请号：US16034794
申请日：2018-07-13
Applicant: Edwards Lifesciences Corporation
Inventor： Liron Tayeb , Eran Goldberg , David Maimon , Adi Carmi , Arie Tylis , Ofir Witzman , Ralph Schneider , Mohammad Jafari , Hengchu Cao , Eason Michael Abbott , Dustin P. Armer , Michael D. Franklin , Tomer Saar , Anatoly Dvorsky , John J. Desrosiers , Daniel James Murray , Michael G. Valdez , Assaf Bash , Amir Blumenfeld , Noa Axelrod , Eitan Atias
IPC: A61F2/24
Abstract: Docking stations for transcatheter valves are described. The docking stations can include an expandable frame, at least one sealing portion, and a valve seat. The expandable frame can be configured to conform to an interior shape of a portion of the circulatory system when expanded inside the circulatory system. The sealing portion can be configured to contact an interior surface of the circulatory system to create a seal. The valve seat can be connected to the expandable frame and can be configured to support an expandable transcatheter valve. The docking stations are adaptable to different anatomies/locations to allow implantation of a transcatheter valve in a variety of anatomies/locations.
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Patent Agency Ranking
公开(公告)号：US20170224323A1
公开(公告)日：2017-08-10
申请号：US15416595
申请日：2017-01-26
Applicant: Edwards Lifesciences Corporation
Inventor： Stanton J. Rowe , Ming H. Wu , Jinny Lee , Ralph Schneider , Sergio Delgado , Ilan Tamir
CPC classification number: A61B17/0218 , A61B17/0057 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00601 , A61B2017/00606 , A61B2017/00623 , A61B2017/00632 , A61B2017/0225 , A61B2017/0237 , A61F2/2427
Abstract: A septal closure and port device for implantation in the atrial septum of a patient's heart includes an expandable frame having a central portion defining a lumen, and first and second opposing end portions. The frame is configured to expand and contract between a compressed, tubular configuration for delivery through the patient's vasculature and an expanded configuration in which the first and second end portions extend radially outwardly from the opposite ends of the central portion. The device can further include a valve member supported on the frame and positioned to block at least the flow of blood from the left atrium to the right atrium through the lumen of the frame. The valve member is configured to permit a medical instrument to be inserted through the lumen and into the left atrium, such as for performing a subsequent medical procedure in the left side of the heart.
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公开(公告)号：US20170071731A1
公开(公告)日：2017-03-16
申请号：US15357990
申请日：2016-11-21
Applicant: Edwards Lifesciences Corporation
Inventor： Jeffrey S. Dove , Bin Tian , Ralph Schneider , Jeffrey S. Cohen , Ivan Jankovic , John F. Migliazza , Gregory A. Wright , James M. Young , Louis A. Campbell
CPC classification number: A61F2/2415 , A61B18/20 , A61F2/02 , A61F2/24 , A61F2/2409 , A61F2/2418 , A61F2002/30324 , A61F2250/0036 , A61L27/3604 , A61L27/3625 , A61L27/3691 , A61L27/507 , A61L2300/60 , A61L2430/20 , B65B55/18 , B65B63/02
Abstract: Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smoothes the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes.
Abstract translation: 生物假体材料调理方法采用牛心包膜。 指向膜的纤维表面并相对于其移动的激光将膜的厚度减小到特定的均匀厚度并平滑表面。 选择激光器的波长，功率和脉冲速率，这将使纤维表面平滑，并将表面烧蚀到合适的厚度。 或者，使用皮肤表面从膜的纤维表面去除一层材料。 变薄也可能采用压缩。 使用交联以稳定膜的逐步压缩来避免通过非弹性压缩损伤膜。 相反，膜通过加成交联结合在弹性压缩状态。 上述几种稀释技术可以一起使用以获得强的薄膜。
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公开(公告)号：US09504571B2
公开(公告)日：2016-11-29
申请号：US13910975
申请日：2013-06-05
Applicant: Edwards Lifesciences Corporation
Inventor： Stanton J. Rowe , Alexander J. Siegel , Ralph Schneider
CPC classification number: A61F2/2466 , A61B17/0401 , A61B2017/00243 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0427 , A61B2017/0464 , A61B2017/0472 , A61F2/2448
Abstract: Disclosed systems for implanting annuloplasty rings and other prosthetic devices can comprise a plurality of microanchors, sutures threaded through the microanchors, the sutures passing through the prosthetic device, individual microanchor guides, such as tubes or spears, for each microanchor that contain the microanchors during delivery and allow for positioning and deployment of the microanchors into annular tissue. The systems can also comprise a bracket that is temporarily coupled to the prosthetic device, holds the plurality of microanchor guides in position relative to one another and relative to the prosthetic device, and/or guides the sutures passing through the prosthetic device. The prosthetic device can include suture locking mechanisms to secure the prosthetic device to the sutures and to the implanted microanchors after the deployment devices have been removed.
Abstract translation: 用于植入瓣膜成形术环和其他假体装置的公开的系统可以包括多个微型锚杆，穿过微型锚杆的缝合线，穿过假体装置的缝合线，用于在递送期间包含微量锚杆的每个微型锚杆的单独的微导向件，例如管或矛 并允许将微型锚定件定位和展开到环形组织中。 系统还可以包括临时联接到假体装置的支架，其将多个微导管引导件相对于彼此并相对于假体装置保持在适当位置，和/或引导通过假肢装置的缝合线。 假体装置可以包括缝合线锁定机构，以在拆除部署装置之后将修复装置固定到缝合线和植入的微型锚固器。
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公开(公告)号：US09498288B2
公开(公告)日：2016-11-22
申请号：US13950154
申请日：2013-07-24
Applicant: Edwards Lifesciences Corporation
Inventor： Jeffrey S. Dove , Bin Tian , Ralph Schneider , Jeffrey S. Cohen , Ivan Jankovic , John F. Migliazza , Gregory A. Wright , James Young , Louis A. Campbell
CPC classification number: A61F2/2415 , A61B18/20 , A61F2/02 , A61F2/24 , A61F2/2409 , A61F2/2418 , A61F2002/30324 , A61F2250/0036 , A61L27/3604 , A61L27/3625 , A61L27/3691 , A61L27/507 , A61L2300/60 , A61L2430/20 , B65B55/18 , B65B63/02
Abstract: Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smoothes the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes.
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公开(公告)号：US09492230B2
公开(公告)日：2016-11-15
申请号：US13621680
申请日：2012-09-17
Applicant: Edwards Lifesciences Corporation
Inventor： Ralph Schneider , Bin Tian , Jeffrey S. Dove , Jeff Cohen , Ivan Jankovic , John F. Migliazza , Gregory A. Wright , James Young , Louis A. Campbell
CPC classification number: A61F2/2415 , A61B18/20 , A61F2/02 , A61F2/24 , A61F2/2409 , A61F2/2418 , A61F2002/30324 , A61F2250/0036 , A61L27/3604 , A61L27/3625 , A61L27/3691 , A61L27/507 , A61L2300/60 , A61L2430/20 , B65B55/18 , B65B63/02
Abstract: Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smoothes the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes.
Abstract translation: 生物假体材料调理方法采用牛心包膜。 指向膜的纤维表面并相对于其移动的激光将膜的厚度减小到特定的均匀厚度并平滑表面。 选择激光器的波长，功率和脉冲速率，这将使纤维表面平滑，并将表面烧蚀到合适的厚度。 或者，使用皮肤表面从膜的纤维表面去除一层材料。 变薄也可能采用压缩。 使用交联以稳定膜的逐步压缩来避免通过非弹性压缩损伤膜。 相反，膜通过加成交联结合在弹性压缩状态。 上述几种稀释技术可以一起使用以获得强的薄膜。
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