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公开(公告)号：US10350062B2
公开(公告)日：2019-07-16
申请号：US15653390
申请日：2017-07-18
Applicant: Edwards Lifesciences Corporation
Inventor： Matthew A. Peterson , Seung-Beom Yi , Siddharth Vad , Travis Zenyo Oba , Lauren R. Freschauf , Amanda French , Yaron Keidar , Yuanlong Du , Gregory Bak-Boychuk , Kevin M. Golemo , Alexander H. Cooper
IPC: A61F2/24
Abstract: A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body. The expandable frame can include a frame body and a supplemental frame. The valve body can include a plurality of leaflets and one or more intermediate components. The one or more intermediate components can couple at least a portion of the leaflets to the expandable frame. The prosthesis can include an annular flap positioned around an exterior of the expandable frame.
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公开(公告)号：US09439763B2
公开(公告)日：2016-09-13
申请号：US14171603
申请日：2014-02-03
Applicant: Edwards Lifesciences Corporation
Inventor： Stephen C. Geist , Robert C. Taft , Travis Oba , Sam Sok , Matthew A. Peterson , Kevin M. Golemo , Mark Chau , Seung-Beom Yi
CPC classification number: A61F2/2418 , A61B6/4441 , A61B8/12 , A61F2/2409 , A61F2/2412 , A61F2/2436 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0018 , A61F2250/0029 , A61F2250/0069
Abstract: Embodiments of prosthetic valves for implantation within a native mitral valve are provided. One embodiment of a prosthetic valve includes a radially compressible main body and a one-way valve member. In some cases, the prosthetic valves also include ventricular anchors and/or an atrial portion coupled to and disposed outside of the main body. Methods, devices, and systems for delivering such prosthetic valves to the native mitral valve and implanting them therein are also provided.
Abstract translation: 提供了用于植入在天然二尖瓣内的人工瓣膜的实施例。 假体瓣膜的一个实施例包括可径向压缩的主体和单向阀构件。 在一些情况下，假体瓣膜还包括联接到并设置在主体外侧的心室锚和/或心房部分。 还提供了用于将这种假性瓣膜递送到天然二尖瓣并将其植入其中的方法，装置和系统。
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公开(公告)号：US10799347B1
公开(公告)日：2020-10-13
申请号：US16906672
申请日：2020-06-19
Applicant: Edwards Lifesciences Corporation
Inventor： Stephen C. Geist , Robert C. Taft , Travis Zenyo Oba , Sam Sok , Matthew A. Peterson , Kevin M. Golemo , Mark Chau , Seung-Beom Yi
Abstract: An implantable prosthetic valve includes a radially collapsible and radially expandable annular frame. The frame includes an annular main body sized to be implanted within a native mitral valve annulus. The frame also includes an atrial sealing member coupled to and extending radially away from the main body. The atrial sealing member is sized to extend over tissue of the native mitral annulus within a left atrium to reduce paravalvular leakage. The atrial sealing member includes an inner zig-zag portion and an outer zig-zag portion. The inner zig-zag portion and the outer zig-zag portion are connected to the main body portion only via a fabric to enhance flexibility of the atrial sealing member relative to the main body. The prosthetic valve also includes a valve member disposed within an interior of the frame.
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公开(公告)号：US20200060818A1
公开(公告)日：2020-02-27
申请号：US16670449
申请日：2019-10-31
Applicant: Edwards Lifesciences Corporation
Inventor： Stephen C. Geist , Robert C. Taft , Travis Zenyo Oba , Sam Sok , Matthew A. Peterson , Kevin M. Golemo , Mark Chau , Seung-Beom Yi
IPC: A61F2/24
Abstract: A method of implanting a prosthetic apparatus preferably includes delivering the prosthetic apparatus to a native mitral valve and exposing ventricular anchors and a spacer body of the prosthetic apparatus from a distal end portion of a delivery apparatus. The ventricular anchors are controllably and forcibly expanded outwardly from the spacer body to an expanded configuration. The prosthetic apparatus is positioned relative to the native mitral valve such that native mitral valve leaflets are located between the ventricular anchors and the spacer body. The ventricular anchors are then contracted radially inwardly toward the spacer body to a compressed configuration. In the compressed configuration, the native mitral valve leaflets are secured between the ventricular anchors and the spacer body. After implantation, the spacer body is held between the native mitral valve leaflets, thereby blocking regurgitation and improving the function of the native mitral valve.
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公开(公告)号：US10463481B2
公开(公告)日：2019-11-05
申请号：US15259988
申请日：2016-09-08
Applicant: Edwards Lifesciences Corporation
Inventor： Stephen C. Geist , Robert C. Taft , Travis Zenyo Oba , Sam Sok , Matthew A. Peterson , Kevin M. Golemo , Mark Chau , Seung-Beom Yi
Abstract: A prosthetic heart valve includes a collapsible and expandable frame having a main body, an atrial portion, and at least one ventricular anchor. The atrial portion extends radially outwardly relative to the main body and the ventricular anchor extends from a ventricular end of the main body. The main body and the atrial portion are preferably separate metal components that are coupled together via sutures or a fabric member. The prosthetic heart valve also includes a valve structure that is supported in the main body of the frame. The valve structure has a plurality of leaflets for regulating the flow of blood in one direction.
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Patent Agency Ranking
公开(公告)号：US20180021129A1
公开(公告)日：2018-01-25
申请号：US15653390
申请日：2017-07-18
Applicant: Edwards Lifesciences Corporation
Inventor： Matthew A. Peterson , Seung-Beom Yi , Siddharth Vad , Travis Zenyo Oba , Lauren R. Freschauf , Amanda French , Yaron Keidar , Yuanlong Du , Gregory Bak-Boychuk , Kevin M. Golemo , Alexander H. Cooper
IPC: A61F2/24
CPC classification number: A61F2/2412 , A61F2/2409 , A61F2/2418 , A61F2/2427 , A61F2/2436 , A61F2210/0014 , A61F2210/0076 , A61F2220/0008 , A61F2230/0013 , A61F2230/0054 , A61F2250/0003 , A61F2250/0014 , A61F2250/0018 , A61F2250/0036 , A61F2250/0039 , A61F2250/0063 , A61F2250/0069
Abstract: A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body. The expandable frame can include a frame body and a supplemental frame. The valve body can include a plurality of leaflets and one or more intermediate components. The one or more intermediate components can couple at least a portion of the leaflets to the expandable frame. The prosthesis can include an annular flap positioned around an exterior of the expandable frame.
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公开(公告)号：US20170231759A1
公开(公告)日：2017-08-17
申请号：US15259988
申请日：2016-09-08
Applicant: Edwards Lifesciences Corporation
Inventor： Stephen C. Geist , Robert C. Taft , Travis Zenyo Oba , Sam Sok , Matthew A. Peterson , Kevin M. Golemo , Mark Chau , Seung-Beom Yi
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61B6/4441 , A61B8/12 , A61F2/2409 , A61F2/2412 , A61F2/2436 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0018 , A61F2250/0029 , A61F2250/0069
Abstract: A prosthetic heart valve includes a collapsible and expandable frame having a main body, an atrial portion, and at least one ventricular anchor. The atrial portion extends radially outwardly relative to the main body and the ventricular anchor extends from a ventricular end of the main body. The main body and the atrial portion are preferably separate metal components that are coupled together via sutures or a fabric member. The prosthetic heart valve also includes a valve structure that is supported in the main body of the frame. The valve structure has a plurality of leaflets for regulating the flow of blood in one direction.
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公开(公告)号：US20240325144A1
公开(公告)日：2024-10-03
申请号：US18742979
申请日：2024-06-13
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Stephen C. Geist , Robert C. Taft , Travis Zenyo Oba , Sam Sok , Matthew A. Peterson , Kevin M. Golemo , Mark Chau , Seung-Beom Yi
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2412 , A61F2/2436 , A61F2/2466 , A61B6/4441 , A61B8/12 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0018 , A61F2250/0029 , A61F2250/0069
Abstract: A prosthetic heart valve for implantation within a native atrioventricular heart valve. The prosthetic heart valve includes a self-expanding frame having an annular main body and a valve member disposed within the main body. The prosthetic heart valve includes an atrial sealing member formed by a fabric cover and a plurality of arms that are arranged side-by-side in a circumferential direction around the main body. The atrial sealing member extends radially outwardly from the main body and a peripheral portion of the atrial sealing member curves upwardly for conforming to surrounding native anatomy. The prosthetic heart valve further includes one or more ventricular anchors extending from the main body for capturing native leaflet tissue and thereby securing the prosthetic heart valve within the native atrioventricular heart valve.
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公开(公告)号：US11224507B2
公开(公告)日：2022-01-18
申请号：US16506886
申请日：2019-07-09
Applicant: Edwards Lifesciences Corporation
Inventor： Matthew A. Peterson , Seung-Beom Yi , Siddharth Vad , Travis Zenyo Oba , Lauren R. Freschauf , Amanda French , Yaron Keidar , Yuanlong Du , Gregory Bak-Boychuk , Kevin M. Golemo , Alexander H. Cooper
IPC: A61F2/24
Abstract: A heart valve prosthesis for replacing a native mitral valve includes a self-expanding frame with a plurality of anchoring members disposed along the lower region. A valve body is positioned within the self-expanding frame and includes a plurality of leaflets configured to allow blood flow through the self-expanding frame in only one direction. A skirt surrounds the self-expanding frame and is spaced apart therefrom for contacting surrounding tissue and impeding blood flow around the self-expanding frame. The skirt may be reinforced with wires to help maintain a desired shape. The leaflets in the valve body are preferably connected to the self-expanding frame through one or more intermediate components such that the valve body is spaced radially inwardly from an inner surface of the self-expanding frame.
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公开(公告)号：US11123186B2
公开(公告)日：2021-09-21
申请号：US16027974
申请日：2018-07-05
Applicant: Edwards Lifesciences Corporation
Inventor： David Robert Landon , Alexander H. Cooper , Julio Cesar Sanchez , Glen T. Rabito , Victoria Cheng-Tan Wu , Kevin M. Golemo , J. Brent Ratz , Tarannum Ishaq Gutierrez , Ramon Aguilar, Jr. , Taylor Jacob Scheinblum , Kevin M. Stewart , Garrett Dallas Johnson , Jesse Robert Edwards , Hieu Minh Luong , Lindsay Lam
Abstract: Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. Disclosed are a number of features that can improve steerability or release of the prosthesis into the body location.
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