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公开(公告)号：US20200315795A1
公开(公告)日：2020-10-08
申请号：US16908375
申请日：2020-06-22
Applicant: Edwards Lifesciences Corporation
Inventor： Frederic B. Hodshon , Rafael Pintor , August R. Yambao , Abhishek Gautam , Louis A. Campbell , Lawrence J. Farhat , Tammy Huntley , Faisal Kalam , Travis Zenyo Oba , Qinggang Zeng
Abstract: Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within ajar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly.
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公开(公告)号：US20200214838A1
公开(公告)日：2020-07-09
申请号：US16818992
申请日：2020-03-13
Applicant: Edwards Lifesciences Corporation
Inventor： Louis A. Campbell , Andrew Phung
Abstract: An improved holder and storage system for prosthetic heart valves that pre-shields or pre-constricts the commissure posts of the valve to prevent suture looping. Pre-shielding and pre-constriction mean at the time of manufacture, so that the valves are stored with the commissure posts shielded and/or constricted. The holders may have solid legs that directly contact and constrict and hold the commissure posts without the use of sutures in tension that might creep over the time in storage. The holder may have a base in contact with the inflow end and a shaft portion that projects through the valve leaflets and cooperates with movable legs on the outflow end of the valve in contact with the commissure posts. The holders may, alternatively, have flexible leg members that extend through the valve and have distal end portions configured to extend over and shield the tips of commissure posts.
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公开(公告)号：US20200163764A1
公开(公告)日：2020-05-28
申请号：US16779134
申请日：2020-01-31
Applicant: Edwards Lifesciences Corporation
Inventor： Donald E. Bobo, JR. , Assaf Bash , Louis A. Campbell , Alison S. Curtis , Tak G. Cheung , John F. Migliazza
IPC: A61F2/24
Abstract: Devices and related methods of use are provided for improving heart function. In one embodiment of the present disclosure, a device includes a ring-like structure configured to be secured to a heart valve; at least one elongate member extending from the ring-like structure, wherein an end of the elongate member is configured to be secured to heart geometry other than a heart valve; and an adjustment mechanism for simultaneously altering a dimension of the ring-like structure and a length of the elongate member.
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公开(公告)号：US20200093593A1
公开(公告)日：2020-03-26
申请号：US16695008
申请日：2019-11-25
Applicant: Edwards Lifesciences Corporation
Inventor： Visith Chung , Da-Yu Chang , Brian S. Conklin , Grace Myong Kim , Louis A. Campbell , Donald E. Bobo, JR. , Myron Howanec , David S. Lin , Peng Norasing , Francis M. Tran , Mark Van Nest , Thomas Chien , Harvey H. Chen , Isidro L. Guerrero , Derrick Johnson , Paul A. Schmidt
IPC: A61F2/24
Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.
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公开(公告)号：US10456250B2
公开(公告)日：2019-10-29
申请号：US16184234
申请日：2018-11-08
Applicant: Edwards Lifesciences Corporation
Inventor： Louis A. Campbell , Donald E. Bobo, Jr. , Gregory A. Wright , Tak G. Cheung
Abstract: A valved conduit including a bioprosthetic valve, such as a heart valve, and a tubular conduit sealed with a bioresorbable material. The bioprosthetic heart valve includes prosthetic tissue that has been treated such that the tissue may be stored dry for extended periods without degradation of functionality of the valve. The bioprosthetic heart valve may have separate bovine pericardial leaflets or a whole porcine valve. The sealed conduit includes a tubular matrix impregnated with a bioresorbable medium such as gelatin or collagen. The valved conduit is stored dry in packaging in which a desiccant pouch is supplied having a capacity for absorbing moisture within the packaging limited to avoid drying the bioprosthetic tissue out beyond a point where its ability to function in the bioprosthetic heart valve is compromised. The heart valve may be sewn within the sealed conduit or coupled thereto with a snap-fit connection.
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Patent Agency Ranking
公开(公告)号：US20180289475A1
公开(公告)日：2018-10-11
申请号：US16007879
申请日：2018-06-13
Applicant: Edwards Lifesciences Corporation
Inventor： Visith Chung , Da-Yu Chang , Brian S. Conklin , Grace Myong Kim , Louis A. Campbell , Donald E. Bobo, JR. , Myron Howanec, JR. , David S. Lin , Peng Norasing , Francis M. Tran , Mark Van Nest , Thomas H. Chien , Harvey H. Chen , Isidro L. Guerrero , Derrick Johnson , Paul A. Schmidt
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2433 , A61F2/2445 , A61F2210/0004 , A61F2220/0033 , A61F2220/0075 , A61F2230/0054 , A61F2250/0004 , A61F2250/001 , A61F2250/006 , A61F2250/0063 , A61F2250/0071 , A61F2310/00011
Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.
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公开(公告)号：US10052200B2
公开(公告)日：2018-08-21
申请号：US15190094
申请日：2016-06-22
Applicant: Edwards Lifesciences Corporation
Inventor： Visith Chung , Da-Yu Chang , Brian S. Conklin , Grace Myong Kim , Louis A. Campbell , Donald E. Bobo, Jr. , Myron Howanec, Jr. , David S. Lin , Peng Norasing , Francis M. Tran , Mark Van Nest , Thomas H. Chien , Harvey H. Chen , Isidro L. Guerrero , Derrick Johnson , Paul A. Schmidt
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2433 , A61F2/2445 , A61F2210/0004 , A61F2220/0033 , A61F2220/0075 , A61F2250/0004 , A61F2250/001 , A61F2250/006 , A61F2250/0063 , A61F2250/0071 , A61F2310/00011
Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.
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公开(公告)号：US20150351909A1
公开(公告)日：2015-12-10
申请号：US14827216
申请日：2015-08-14
Applicant: Edwards Lifesciences Corporation
Inventor： Donald E. Bobo, Jr. , Assaf Bash , Louis A. Campbell , Alison S. Curtis , Tak G. Cheung , John F. Migliazza
IPC: A61F2/24
CPC classification number: A61F2/2445 , A61B5/1076 , A61B6/503 , A61F2/2457 , A61F2/2487 , A61F2220/0008 , A61F2250/0004 , A61F2250/0007 , A61F2250/0012
Abstract: Devices and related methods of use are provided for improving heart function. In one embodiment of the present disclosure, a device includes a ring-like structure configured to be secured to a heart valve; at least one elongate member extending from the ring-like structure, wherein an end of the elongate member is configured to be secured to heart geometry other than a heart valve; and an adjustment mechanism for simultaneously altering a dimension of the ring-like structure and a length of the elongate member.
Abstract translation: 提供了用于改善心脏功能的装置和相关使用方法。 在本公开的一个实施例中，装置包括构造成固定到心脏瓣膜的环状结构; 至少一个从所述环状结构延伸的细长构件，其中所述细长构件的端部构造成固定到心脏瓣膜以外的心脏几何形状; 以及用于同时改变环状结构的尺寸和细长构件的长度的调节机构。
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公开(公告)号：US09078652B2
公开(公告)日：2015-07-14
申请号：US13920983
申请日：2013-06-18
Applicant: Edwards Lifesciences Corporation
Inventor： Brian S. Conklin , Louis A. Campbell , Salvador Marquez , Donald E. Bobo, Jr.
IPC: A61B17/04
CPC classification number: A61B17/0487 , A61B17/0401 , A61B2017/0404 , A61B2017/0409 , A61B2017/0414 , A61B2017/0416 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61F2/24 , A61F2/2409 , A61F2/2442
Abstract: Suture locking clamps for securing prostheses such as heart valves or annuloplasty rings with sutures and without knots improve the ease of implantation. The clamps have opposed clamp halves separated by a slot opening to one side and surrounded by a biasing member such as one or more C-clip springs. Sutures pass laterally into the slot which is held open by a retention member positioned between the clamp halves. The locking clamp slides along the sutures into position, the tension of the sutures is adjusted, and the retention member removed to allow the biasing member to clamp the sutures between the clamp halves. A delivery tool used to deliver and deploy the locking clamps contains a number of clamps within a delivery tube in a stack and bonded together for safety and a common retention member. The tool has a longitudinal channel on one side for entry of sutures.
Abstract translation: 用于固定假体（例如心脏瓣膜或带有缝线和瓣环的瓣环成形术环）的缝合线锁定件提高了植入的容易性。 夹具具有相对的夹具半部，该半部由通向一侧的狭槽分开，并被诸如一个或多个C形夹弹簧的偏置构件包围。 缝合线横向穿过狭槽，狭槽由位于夹子半部之间的保持构件保持打开。 锁定夹具沿着缝合线滑动到适当位置，调节缝合线的张力，并且移除保持构件以允许偏置构件将缝合线夹在夹具半部之间。 用于传送和展开锁定夹具的输送工具在堆叠中的输送管内包含多个夹具，并且为了安全而将其粘合在一起并具有公共保持构件。 该工具在一侧具有用于进入缝合线的纵向通道。
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公开(公告)号：US20130325111A1
公开(公告)日：2013-12-05
申请号：US13906166
申请日：2013-05-30
Applicant: Edwards Lifesciences Corporation
Inventor： Louis A. Campbell , Donald E. Bobo, JR. , Gregory A. Wright , Tak G. Cheung
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/0095 , A61F2/06 , A61F2/2409 , A61F2/2412 , A61F2/2415 , A61F2/2427 , A61F2210/0004 , A61F2220/0075 , A61F2310/00371 , A61F2310/00383 , A61L27/222 , A61L27/24 , A61L27/3625 , A61L27/3687 , A61L27/507 , A61L2430/20 , A61L2430/40
Abstract: A valved conduit including a bioprosthetic valve, such as a heart valve, and a tubular conduit sealed with a bioresorbable material. The bioprosthetic heart valve includes prosthetic tissue that has been treated such that the tissue may be stored dry for extended periods without degradation of functionality of the valve. The bioprosthetic heart valve may have separate bovine pericardial leaflets or a whole porcine valve. The sealed conduit includes a tubular matrix impregnated with a bioresorbable medium such as gelatin or collagen. The valved conduit is stored dry in packaging in which a desiccant pouch is supplied having a capacity for absorbing moisture within the packaging limited to avoid drying the bioprosthetic tissue out beyond a point where its ability to function in the bioprosthetic heart valve is compromised. The heart valve may be sewn within the sealed conduit or coupled thereto with a snap-fit connection.
Abstract translation: 包括生物假体瓣膜（例如心脏瓣膜）和用生物可再吸收材料密封的管状导管的阀门导管。 生物假体心脏瓣膜包括经过处理的假体组织，使得组织可以长时间保存干燥，而不会降低瓣膜的功能。 生物假体心脏瓣膜可以具有单独的牛心包瓣或整个猪瓣。 密封导管包括浸渍有生物可吸收介质如明胶或胶原的管状基质。 带阀的导管在包装中储存，其中提供干燥剂袋，其具有吸收包装内的水分的能力，以避免将生物假体组织干燥超过其在生物假体心脏瓣膜中起作用的能力受损的程度。 心脏瓣膜可以缝合在密封导管内或用卡扣配合连接在其上。
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