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公开(公告)号:US20180153689A1
公开(公告)日:2018-06-07
申请号:US15831197
申请日:2017-12-04
Applicant: Edwards Lifesciences Corporation
Inventor: David Maimon , Boaz Manash , Eyal Leiba , Ziv Yohanan , Yair A. Neumann , Anatoly Dvorsky , Jonathan Bar-Or , Oren Cohen , Ofir Witzman , Liron Tayeb , Elazar Levi Schwarcz , Noam Miller , Tomer Saar
IPC: A61F2/24
Abstract: An assembly can comprise a radially expandable and compressible annular frame, at least one linear actuator assembly coupled to the frame and at least one locking mechanism coupled to the frame. The linear actuator can be configured to apply a distally directed force and/or a proximally directed force to the frame to radially expand or compress the frame. The locking mechanism can comprise a first sleeve member connected to the frame at a first location, a second sleeve member having internal threads and being connected to the frame at a second location, and a first screw configured to engage the internal threads of the second sleeve member to retain the frame in a radially expanded state.
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公开(公告)号:US12048623B2
公开(公告)日:2024-07-30
申请号:US17492408
申请日:2021-10-01
Applicant: Edwards Lifesciences Corporation
Inventor: Nikolay Gurovich , Michael Bukin , Alexey Tsypenyuk , Elena Sherman , Dikla Kersh , Boaz Manash , Liron Tayeb , Ziv Yohanan , Alexander Barash , Yair A. Neumann , Tomer Saar
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2220/0033 , A61F2220/0075 , A61F2220/0091 , A61F2230/0069
Abstract: A prosthetic valve has an annular frame including a plurality of strut members that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. A leaflet structure is situated at least partially within the frame. The leaflet structure includes a plurality of leaflets, each leaflet having opposing commissure tab portions on opposite sides of the leaflet. Each commissure tab portion is paired with an adjacent commissure tab portion of an adjacent leaflet to form a commissure. The commissure tab portions of each leaflet are folded to form a plurality of layers positioned on the inside of the frame. A reinforcement member is positioned between the layers of each commissure tab portion.
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公开(公告)号:US11925550B2
公开(公告)日:2024-03-12
申请号:US17694578
申请日:2022-03-14
Applicant: Edwards Lifesciences Corporation
Inventor: Tomer Saar , Michael Bukin , Elena Sherman , Alexander Barash , Yana Mayatskaya
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2210/0014 , A61F2220/0075
Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame including a plurality of angled strut members, a plurality of leaflets disposed within the frame and secured to the frame, and a skirt member secured to the frame. The skirt member is disposed about an edge portion of a leaflet of the plurality of leaflets, and the skirt member includes a plurality of extension portions wrapped around at least one strut member. A cord member is threaded through at least a portion of the plurality of extension portions in a direction along an axis of the at least one strut member to secure the skirt member to the at least one strut member.
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公开(公告)号:US20230372093A1
公开(公告)日:2023-11-23
申请号:US18358845
申请日:2023-07-25
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Michael Bukin , Nikolai Gurovich , Noam Nir , Tomer Saar , Tamir S. Levi
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2250/0069
Abstract: The present invention relates to implantable prosthetic devices, and more particularly, to 3D-shaped skirts having various coatings and/or configurations thereof.
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公开(公告)号:US20230157802A1
公开(公告)日:2023-05-25
申请号:US18094864
申请日:2023-01-09
Applicant: Edwards Lifesciences Corporation
Inventor: Noam Nir , Carmel Peleg , Tomer Saar , Alexander Barash , David Maimon
CPC classification number: A61F2/0095 , A61F2/24 , A61F2/9525 , A61F2/9522 , A61F2/9524
Abstract: Disclosed herein is a storage container for an expandable prosthetic heart valve that crimps the valve upon opening the container and removal of the valve from the container. The container includes a housing sized to receive the heart valve in its expanded configuration and a crimping mechanism. The crimping mechanism is incorporated into the container and engages the heart valve so as to operably convert the heart valve from its expanded configuration to its smaller crimped configuration upon opening the container and removing the valve.
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公开(公告)号:US11510794B2
公开(公告)日:2022-11-29
申请号:US16935044
申请日:2020-07-21
Applicant: Edwards Lifesciences Corporation
Inventor: Tomer Saar , Gregory Rinberg
Abstract: Disclosed herein is a method of crimping a prosthetic heart valve using a compact crimping mechanism. The crimping mechanism includes a plurality of jaws configured for coordinated inward movement toward a crimping axis to reduce the size of a crimping iris around a stented valve. A rotating cam wheel acts on the jaws and displaces them inward. A number of Cartesian guide elements cooperate with the jaws to distribute forces within the crimping mechanism. The guide elements are located between the crimping jaws and an outer housing and are constrained by the outer housing for movement along lines that are tangential to a circle centered on the crimping axis. The guide elements engage at least some of the crimping jaws while the rest are in meshing engagement so as to move in synch. An actuation mechanism includes a lead screw, carriage assembly and a linkage to rotate the cam wheel with significant torque.
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公开(公告)号:US20220257128A1
公开(公告)日:2022-08-18
申请号:US17733614
申请日:2022-04-29
Applicant: Edwards Lifesciences Corporation
Inventor: Eran Goldberg , Tamir S. Levi , David Maimon , Oren Cohen , Martyn Rhys Thomas , Tomer Saar , Elazar Levi Schwarcz
IPC: A61B5/0215 , A61F2/24
Abstract: The present invention relates to devices and methods for measuring physiological parameters, such as flow, pressure, temperature, electric conductivity and/or visual indication of thrombus formation or deposits accumulations, prior to, during and/or after prosthetic heart valve implantation procedures.
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公开(公告)号:US20220202569A1
公开(公告)日:2022-06-30
申请号:US17696029
申请日:2022-03-16
Applicant: Edwards Lifesciences Corporation
Inventor: Tomer Saar , Hanoch Cohen-Tzemach , Nadav Ben Zaken
IPC: A61F2/24
Abstract: A prosthetic valve having a frame, a leaflet structure having leaflets forming a primary valve mounted inside the frame, and at least one secondary valve is disclosed. The secondary valve can have a valve element with stationary portion and a detached portion, and at least one aperture in at least one leaflet. The secondary valve can be formed by a portion of at least one leaflet.
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公开(公告)号:US20220104944A1
公开(公告)日:2022-04-07
申请号:US17553688
申请日:2021-12-16
Applicant: Edwards Lifesciences Corporation
Inventor: Oren Cohen , Elazar Levi Schwarcz , Eitan Atias , Tomer Saar
IPC: A61F2/24
Abstract: A medical assembly can include a radially expandable prosthetic heart valve and a delivery apparatus. The delivery apparatus can include a handle, an actuation member, and a force limiting mechanism within the handle including a pivot arm coupled to a base portion. The actuation member can apply a proximally directed force to the prosthetic valve to cause the valve to expand. The actuation member can be coupled to the pivot arm such that a force applied to the actuation member causes the pivot arm to pivot. The force limiting mechanism can pinch the actuation member between the pivot arm and the base portion when the force applied to the actuation member exceeds a predetermined force to prevent proximal movement of the actuation member and can allow proximal movement of the actuation member to produce radial expansion of the prosthetic valve when the force applied is less than the predetermined force.
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公开(公告)号:US20220023038A1
公开(公告)日:2022-01-27
申请号:US17492408
申请日:2021-10-01
Applicant: Edwards Lifesciences Corporation
Inventor: Nikolay Gurovich , Michael Bukin , Alexey Tsypenyuk , Elena Sherman , Dikla Kersh , Boaz Manash , Liron Tayeb , Ziv Yohanan , Alexander Barash , Yair A. Neumann , Tomer Saar
IPC: A61F2/24
Abstract: A prosthetic valve has an annular frame including a plurality of strut members that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. A leaflet structure is situated at least partially within the frame. The leaflet structure includes a plurality of leaflets, each leaflet having opposing commissure tab portions on opposite sides of the leaflet. Each commissure tab portion is paired with an adjacent commissure tab portion of an adjacent leaflet to form a commissure. The commissure tab portions of each leaflet are folded to form a plurality of layers positioned on the inside of the frame. A reinforcement member is positioned between the layers of each commissure tab portion.
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