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公开(公告)号：US20200214840A1
公开(公告)日：2020-07-09
申请号：US16820499
申请日：2020-03-16
Applicant: Edwards Lifesciences Corporation
Inventor： Kevin D. Rupp , Tung T. Le , Thanh Huy Le , Brian C. Gray , Alejandro J. Froimovich Rosenberg , Jeff Lindstrom , Kim D. Nguyen , Sonny Tran
IPC: A61F2/24
Abstract: A delivery apparatus for implanting a radially compressible and expandable prosthetic heart valve in a native heart valve of the heart includes a handle portion and an elongated shaft extending from and movable relative to the handle portion. The shaft includes a proximal end portion coupled to the handle portion and a distal end portion configured to mount a prosthetic heart valve in a radially compressed state. The handle portion includes a control member movable longitudinally with respect to the handle portion, the control member engaging a gear assembly operable to convert longitudinal motion of the control member to rotational motion of the gear assembly. The gear assembly engages the elongated shaft such that rotational motion of the gear assembly causes corresponding longitudinal motion of the elongated shaft relative to the handle portion.
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公开(公告)号：US20160317305A1
公开(公告)日：2016-11-03
申请号：US15140387
申请日：2016-04-27
Applicant: Edwards Lifesciences Corporation
Inventor： Itai Pelled , Elena Sherman , Eran Goldberg , Kevin D. Rupp , Noam Nir
CPC classification number: B29C66/53245 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2210/0076 , A61F2230/0069 , A61F2240/001 , A61F2250/0069
Abstract: The present disclosure relates to laminated sealing members for prosthetic valves and methods of making the same. In a representative embodiment, an implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration comprises an annular frame having an inflow end and an outflow end, a leaflet structure positioned within the frame and secured thereto, and a laminate sealing member comprising an encapsulating material. The laminate sealing member has a main portion that encapsulates at least a portion of the frame and an end portion extending from the inflow end of the frame, and the end portion of the laminate sealing member is folded to form a cuff adjacent the inflow end of the frame and secured to the main portion of the laminate sealing member.
Abstract translation: 本公开涉及用于人造瓣的层压密封构件及其制造方法。 在代表性的实施例中，可径向可折叠到收缩构造并且可径向扩张到扩张构造的可植入假体瓣包括具有流入端和流出端的环形框架，定位在框架内并固定到其上的小叶结构， 层压密封件包括封装材料。 层叠密封构件具有封闭框架的至少一部分的主要部分和从框架的流入端延伸的端部，并且层叠密封构件的端部折叠形成邻近流入端的套筒 框架并固定到层压密封件的主要部分。
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公开(公告)号：US12064341B2
公开(公告)日：2024-08-20
申请号：US16120112
申请日：2018-08-31
Applicant: Edwards Lifesciences Corporation
Inventor： Lien Huong Thi Hoang , Son V. Nguyen , Hien Tran Ngo , Vivian Tran , Russell T. Joseph , Dinesh L. Sirimanne , Kevin D. Rupp , Diana Nguyen-Thien-Nhon
IPC: A61F2/24
CPC classification number: A61F2/2409 , A61F2/2418 , A61F2230/0006 , A61F2230/0069 , A61F2230/0076
Abstract: A prosthetic heart valve includes an annular frame that has an inflow end and an outflow end and is radially compressible and expandable between a radially compressed configuration and a radially expanded configuration. The prosthetic heart valve further includes a leaflet structure positioned within the frame and secured thereto, and an outer sealing member mounted outside of the frame and adapted to seal against surrounding tissue when the prosthetic heart valve is implanted within a native heart valve annulus of a patient. The sealing member can include a mesh layer and pile layer comprising a plurality of pile yarns extending outwardly from the mesh layer.
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公开(公告)号：US20230390049A1
公开(公告)日：2023-12-07
申请号：US18448035
申请日：2023-08-10
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Son V. Nguyen , Kevin D. Rupp , Ajay Chadha , Jeff Lindstrom
IPC: A61F2/24 , D03D3/02 , D03D25/00 , D03D15/283
CPC classification number: A61F2/2409 , D03D3/02 , D03D25/005 , D03D15/283 , D10B2509/00 , A61F2240/004 , A61F2210/0019 , A61F2210/0071 , A61F2220/0075 , A61F2210/0076 , A61F2230/0069 , A61F2250/0069 , A61F2250/006 , A61F2/2418
Abstract: A method of fabricating a docking device involves implementing a three-dimensional (3D) weaving technique to form a 3D textile structure using a plurality of different types of fibers, heating the 3D textile structure on a shape-setting mold at a temperature above a melting point of a first type of fiber of the plurality of different types of fibers to set a cylindrical shape of the 3D textile structure, maintaining the 3D textile structure on the shape-setting mold to cool off for a period of time, and removing the 3D textile structure from the shape-setting mold.
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公开(公告)号：US11707357B2
公开(公告)日：2023-07-25
申请号：US16820499
申请日：2020-03-16
Applicant: Edwards Lifesciences Corporation
Inventor： Kevin D. Rupp , Tung T. Le , Thanh Huy Le , Brian C. Gray , Alejandro J. Froimovich Rosenberg , Jeff Lindstrom , Kim D. Nguyen , Sonny Tran
CPC classification number: A61F2/2433 , A61F2/2418 , A61F2/2436 , A61F2/9517 , A61M25/0136
Abstract: A delivery apparatus for implanting a radially compressible and expandable prosthetic heart valve in a native heart valve of the heart includes a handle portion and an elongated shaft extending from and movable relative to the handle portion. The shaft includes a proximal end portion coupled to the handle portion and a distal end portion configured to mount a prosthetic heart valve in a radially compressed state. The handle portion includes a control member movable longitudinally with respect to the handle portion, the control member engaging a gear assembly operable to convert longitudinal motion of the control member to rotational motion of the gear assembly. The gear assembly engages the elongated shaft such that rotational motion of the gear assembly causes corresponding longitudinal motion of the elongated shaft relative to the handle portion.
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Patent Agency Ranking
公开(公告)号：US20220000619A1
公开(公告)日：2022-01-06
申请号：US17478764
申请日：2021-09-17
Applicant: Edwards Lifesciences Corporation
Inventor： Kevin D. Rupp , Alyssa Joy Gross , Jun Liu , Hamid Rafi , Chambory Chhe , Uy D. Trinh , Duc Hong Nguyen
IPC: A61F2/24
Abstract: A delivery assembly comprises a delivery apparatus and a prosthetic valve releasably connected to a cord-retaining device of the delivery apparatus by a plurality of cords or tethers. The cords desirably have a multi-stranded construction formed from a plurality of strands of material. The multi-stranded construction can be, for example, a braided construction, a twisted construction, or a whip-stitch construction. The multi-stranded construction can include integral openings along opposing end portions of each cord. Each cord can extend through an aperture in an apex of the frame of the prosthetic valve or around an apex with one end portion of the cord being retained on the cord-retaining device and another end portion of the cord being retained on a slideable release member of the delivery apparatus.
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公开(公告)号：US11008676B2
公开(公告)日：2021-05-18
申请号：US15378375
申请日：2016-12-14
Applicant: Edwards Lifesciences Corporation
Inventor： Ajay Chadha , Son V. Nguyen , Kevin D. Rupp
Abstract: A textured fabric for an implantable bioprosthesis is provided. The textured fabric can include a woven base layer and a plurality of loops projecting from the woven base layer. The plurality of loops are formed from a composite core-sheath yarn. The core can be made of a material that is different from the sheath. The core material can be selected to impart strength and resiliency to bending and the sheath material can be selected to impart a larger surface area or texture that facilitates cellular or tissue in-growth.
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公开(公告)号：US20190202140A1
公开(公告)日：2019-07-04
申请号：US16294761
申请日：2019-03-06
Applicant: Edwards Lifesciences Corporation
Inventor： Itai Pelled , Elena Sherman , Eran Goldberg , Kevin D. Rupp , Noam Nir
CPC classification number: B29C66/53245 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2210/0076 , A61F2230/0069 , A61F2240/001 , A61F2250/0069
Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration comprises an annular frame having an inflow end and an outflow end, a leaflet structure positioned within the frame and secured thereto, and a laminate sealing member comprising an encapsulating material. The laminate sealing member has a main portion that encapsulates at least a portion of the frame and an end portion extending from the inflow end of the frame, and the end portion of the laminate sealing member is folded to form a cuff adjacent the inflow end of the frame and secured to the main portion of the laminate sealing member.
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公开(公告)号：US10195025B2
公开(公告)日：2019-02-05
申请号：US14704861
申请日：2015-05-05
Applicant: Edwards Lifesciences Corporation
Inventor： Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. The prosthetic valve can comprise an annular frame, leaflets, an inner skirt, and an outer skirt. The outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack that buckles outward radially when the valve is in the expanded configuration and which lies flat when the valve is in the collapsed configuration. In some embodiments, the outer skirt is stiffer in the axial direction of the valve than in the circumferential direction of the valve. In additional embodiments, the outer skirt comprises a self-expandable fabric comprising fibers made of a shape memory material having a shape memory set to enhance the radially outward buckling of the outer skirt. Methods of crimping such valves to a collapsed or partially collapsed configuration are also disclosed.
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公开(公告)号：US20170065415A1
公开(公告)日：2017-03-09
申请号：US15252110
申请日：2016-08-30
Applicant: Edwards Lifesciences Corporation
Inventor： Kevin D. Rupp , Tung T. Le , Thanh Huy Le , Brian C. Gray , Alejandro J. Froimovich Rosenberg , Jeff Lindstrom , Kim D. Nguyen , Sonny Tran
IPC: A61F2/24
Abstract: A delivery apparatus for implanting a radially compressible and expandable prosthetic heart valve in a native heart valve of the heart includes a handle portion and an elongated shaft extending from and movable relative to the handle portion. The shaft includes a proximal end portion coupled to the handle portion and a distal end portion configured to mount a prosthetic heart valve in a radially compressed state. The handle portion includes a control member movable longitudinally with respect to the handle portion, the control member engaging a gear assembly operable to convert longitudinal motion of the control member to rotational motion of the gear assembly. The gear assembly engages the elongated shaft such that rotational motion of the gear assembly causes corresponding longitudinal motion of the elongated shaft relative to the handle portion.
Abstract translation: 用于将可径向压缩和可扩张的假体心脏瓣膜植入心脏的天然心脏瓣膜的输送装置包括手柄部分和从手柄部分延伸并可相对于手柄部分移动的细长轴。 轴包括联接到手柄部分的近端部分和构造成将假体心脏瓣膜安装在径向压缩状态的远端部分。 手柄部分包括可相对于把手部分纵向移动的控制构件，控制构件接合齿轮组件，该齿轮组件可操作以将控制构件的纵向运动转换为齿轮组件的旋转运动。 齿轮组件接合细长轴，使得齿轮组件的旋转运动引起细长轴相对于把手部分的相应纵向运动。
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