利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

343 条记录 (耗时 0.036 秒)

    Regulatory T cell mediator proteins and uses thereof
    13.
    发明授权
    Regulatory T cell mediator proteins and uses thereof 有权
    调节性T细胞介质蛋白及其用途

    公开(公告)号：US09217035B2

    公开(公告)日：2015-12-22

    申请号：US13901704

    申请日：2013-05-24

    申请人： Randolph J. Noelle ,  Li Wang

    发明人： Randolph J. Noelle ,  Li Wang

    IPC分类号： A61K38/00 ,  C07K14/705 ,  C07K16/28 ,  G01N33/50 ,  A61K39/00

    CPC分类号： C07K16/2827 ,  A61K38/00 ,  A61K2039/505 ,  C07K14/70596 ,  C07K2319/00 ,  C07K2319/30 ,  G01N33/505 ,  Y02A50/412 ,  Y02A50/423

    摘要： The present invention relates to novel regulatory T cell proteins. One protein, designated PD-L3, resembles members of the PD-L1 family, and co-stimulates αCD3 proliferation of T cells in vitro. A second, TNF-like, protein has also been identified as being upregulated upon αCD3/αGITR stimulation. This protein has been designated Treg-sTNF. Proteins, antibodies, activated T cells and methods for using the same are disclosed.In particular methods of using these proteins and compounds, preferably antibodies, which bind or modulate (agonize or antagonize) the activity of these proteins, as immune modulators and for the treatment of cancer, autoimmune disease, allergy, infection and inflammatory conditions, e.g. multiple sclerosis is disclosed.

    摘要翻译： 本发明涉及新型调节性T细胞蛋白。 称为PD-L3的一种蛋白质类似于PD-L1家族的成员，并且在体外共同刺激T细胞的αCD3增殖。 第二种TNF样蛋白也被鉴定为在αCD3/αGITR刺激下上调。 该蛋白质已被命名为Treg-sTNF。 公开了蛋白质，抗体，活化的T细胞及其使用方法。 特别是使用这些蛋白质和化合物（优选抗体）的方法，其结合或调节（激动或拮抗）这些蛋白质的活性，作为免疫调节剂和用于治疗癌症，自身免疫疾病，变态反应，感染和炎性病症，例如， 公开了多发性硬化。

    High exchange capacity perfluorinated ion exchange resin, preparation method and use thereof
    15.
    发明授权
    High exchange capacity perfluorinated ion exchange resin, preparation method and use thereof 有权
    高交换能力的全氟化离子交换树脂，其制备方法和用途

    公开(公告)号：US09090723B2

    公开(公告)日：2015-07-28

    申请号：US13516691

    申请日：2009-12-15

    申请人： Yongming Zhang ,  Heng Zhang ,  Sheng Qin ,  Zihong Gao ,  Li Wang ,  Yong Li ,  Xuezhang Song

    发明人： Yongming Zhang ,  Heng Zhang ,  Sheng Qin ,  Zihong Gao ,  Li Wang ,  Yong Li ,  Xuezhang Song

    IPC分类号： H01M8/10 ,  C08F214/26 ,  C25B13/08 ,  C08J5/22

    CPC分类号： C08F214/265 ,  C08F214/26 ,  C08F214/262 ,  C08F214/267 ,  C08J5/2243 ,  C08J2327/12 ,  H01M8/1023 ,  H01M8/1039 ,  H01M2008/1095 ,  Y02E60/522

    摘要： The present invention provides a high exchange capacity perfluorinated resin comprising two kinds of sulfonyl fluoride-containing short pendant groups of different structures, which is prepared by copolymerizing tetrafluoroethylene, vinyl ether monomers comprising two kinds of sulfonyl fluoride-containing short pendant groups of different structures, and vinyl ether monomer comprising bromine-containing pendant group, wherein based on all monomer units in the copolymer, the mol % of tetrafluoroethylene monomer is 50-85%, the mol % of vinyl ether monomers comprising two kinds of sulfonyl fluoride-containing short pendant groups of different structures is 5-49% and the mol % of vinyl ether monomer comprising bromine-containing pendant group is 1-10%. Perfluorinated ion exchanges membrane prepared from such perfluorinated resin have resistance to various chemical media, high ion exchange capacity, high conductivity, high mechanical strength, high size stability, low membrane electrical resistance and long service life, and may be applied in fuel cells or high-temperature fuel cells.

    摘要翻译： 本发明提供一种高交换能力的全氟化树脂，其包含两种不同结构的含磺酰氟的短侧基，其通过共聚四氟乙烯，包含两种不同结构的含磺酰氟的短侧基的乙烯基醚单体制备， 和含溴侧基的乙烯基醚单体，其中，基于共聚物中的所有单体单元，四氟乙烯单体的摩尔％为50-85％，包含两种含磺酰氟的短侧基的乙烯基醚单体的摩尔％ 不同结构的基团为5-49％，包含含溴侧基的乙烯基醚单体的摩尔％为1-10％。 由这种全氟化树脂制备的全氟化离子交换膜具有耐各种化学介质，高离子交换能力，高导电性，高机械强度，高尺寸稳定性，低膜电阻，使用寿命长等优点，可用于燃料电池或高 燃料电池。

    GARDENING BOX
    16.
    发明申请
    GARDENING BOX 审中-公开
    园艺盒

    公开(公告)号：US20150052808A1

    公开(公告)日：2015-02-26

    申请号：US14010318

    申请日：2013-08-26

    申请人： Li Wang ,  Mingquan Xu ,  Jie Li ,  Steven Lin

    发明人： Li Wang ,  Mingquan Xu ,  Jie Li ,  Steven Lin

    IPC分类号： A01G9/02

    CPC分类号： A01G27/06

    摘要： A gardening box is disclosed. The gardening box may include a main body having a receiving space; a separation board having a plurality of through holes to secure water absorbing units and dividing said receiving space into an upper space and a bottom space; a plurality of observing holes located at a lower portion outside the main body; and a plurality of water absorbing unit secured at the separation board, and a lower portion of the water absorbing unit exposes at the bottom space to absorb water from the bottom space to moisturize soil and plants thereabove. Water level can be observed from the observing holes because the water level of the bottom space is identical to the observing holes according to the law of communicating vases.

    摘要翻译： 公开了园艺盒。 园艺盒可以包括具有容纳空间的主体; 分离板，具有多个通孔以固定吸水单元，并将所述容纳空间分成上部空间和底部空间; 多个观察孔，位于主体外部的下部; 以及多个吸水单元，其固定在分离板上，并且吸水单元的下部在底部空间处露出，以从底部空间吸收水分，从而对其上方的土壤和植物进行滋润。 水位可以从观察孔观察到，因为根据连通花瓶的规律，底部空间的水位与观察孔相同。

    LED activated photocatalyst air filter
    19.
    发明授权
    LED activated photocatalyst air filter 有权
    LED活化光催化剂空气过滤器

    公开(公告)号：US08911670B2

    公开(公告)日：2014-12-16

    申请号：US13197428

    申请日：2011-08-03

    申请人： Li Wang ,  Xuanbin Liu

    发明人： Li Wang ,  Xuanbin Liu

    IPC分类号： A62B7/08 ,  B01D53/86 ,  B01D53/88

    CPC分类号： B01D53/8668 ,  B01D53/88 ,  B01D2255/802 ,  B01D2257/708 ,  B01D2258/06 ,  B01D2259/802 ,  B01D2259/804 ,  Y10T29/49826

    摘要： The present disclosure provides devices and methods for making a light emitting diode (LED) activated photocatalyst air filter. One or more embodiments include a filter material that includes a photocatalyst, and a frame that includes an array of a number of LEDs positioned on the frame to project a wavelength of light directed toward the filter material, wherein the array of LEDs is positioned a distance from the filter material.

    摘要翻译： 本公开提供了制造发光二极管（LED）活化光催化剂空气过滤器的装置和方法。 一个或多个实施例包括包括光催化剂的过滤材料，以及框架，其包括位于框架上的多个LED的阵列以投射指向过滤材料的光的波长，其中LED阵列定位在距离 从过滤材料。