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    MEDICAL PRODUCT WITH A PARTICLE-FREE COATING RELEASING AN ACTIVE SUBSTANCE
    11.
    发明申请
    MEDICAL PRODUCT WITH A PARTICLE-FREE COATING RELEASING AN ACTIVE SUBSTANCE 审中-公开
    具有无颗粒涂层的医疗产品释放活性物质

    公开(公告)号：US20130245058A1

    公开(公告)日：2013-09-19

    申请号：US13577571

    申请日：2011-05-27

    申请人： Erika Hoffmann ,  Michael Hoffmann ,  Roland Horres

    发明人： Erika Hoffmann ,  Michael Hoffmann ,  Roland Horres

    IPC分类号： A61L29/16 ,  A61K31/436 ,  A61K31/337

    CPC分类号： A61L29/16 ,  A61K31/337 ,  A61K31/436 ,  A61L29/08 ,  A61L29/085

    摘要： Embodiments described herein concern medical products, which come into contact with the organism, such as short-term implants and long-term implants, coated with at least one layer, containing a molecular-disperse distributed or dissolved active substance in at least one carrier and optionally one or more adjuvants, wherein the at least one layer forms a stably spreadable solution, methods for making this coating of stably spreadable solution and use of the medical products coated with the stably spreadable solution.

    摘要翻译： 本文描述的实施方案涉及与生物体接触的医疗产品，例如在至少一个载体中包含分子分散分布或溶解的活性物质的至少一层涂覆的短期植入物和长期植入物，以及 任选的一种或多种佐剂，其中所述至少一层形成稳定可铺展的溶液，制备这种涂布稳定可溶解溶液的方法以及使用涂覆有稳定涂布溶液的医疗产品。

    BIODEGRADABLE VASCULAR SUPPORT
    14.
    发明申请
    BIODEGRADABLE VASCULAR SUPPORT 审中-公开
    可生物降解的血管支持

    公开(公告)号：US20100076544A1

    公开(公告)日：2010-03-25

    申请号：US12520976

    申请日：2008-01-30

    申请人： Erika Hoffmann ,  Michael Hoffmann ,  Roland Horres

    发明人： Erika Hoffmann ,  Michael Hoffmann ,  Roland Horres

    IPC分类号： A61F2/82

    CPC分类号： A61L31/022 ,  A61L31/10 ,  A61L31/148 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/42

    摘要： The embodiments described herein are directed to biodegradable stents comprising an inner biodegradable metal scaffold and an outer polymeric coating. The biodegradable coating consists preferentially of biodegradable polymers and may additionally include at least one pharmacologically active substance such as an anti-inflammatory, cytostatic, cytotoxic, antiproliferative, anti-microtubuli, antiangiogenic, antirestenotic (anti-restenosis), antifungicide, antineoplastic, antimigrative, athrombogenic and/or antithrombogenic agent.

    摘要翻译： 本文描述的实施例涉及包含内部可生物降解的金属支架和外部聚合物涂层的可生物降解支架。 可生物降解的涂层优选由可生物降解的聚合物组成，并且还可以包括至少一种药理活性物质，例如抗炎，细胞抑制，细胞毒性，抗增殖，抗微管，抗血管生成，抗再狭窄（抗再狭窄），抗真菌剂，抗肿瘤剂， 促血和/或抗血栓形成剂。