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公开(公告)号：US20190233897A1
公开(公告)日：2019-08-01
申请号：US16122286
申请日：2018-09-05
Applicant: FOUNDATION MEDICINE, INC.
Inventor： Maureen T. Cronin , Garrett Michael Frampton , Doron Lipson , Vincent A. Miller , Gary Palmer , Jeffrey S. Ross , Philip James Stephens , Roman Yelensky
IPC: C12Q1/6886 , A61K31/675 , A61K31/4196 , A61K31/439 , A61K45/06 , A61K31/567 , A61K31/565 , A61K31/436 , A61K31/4439 , C07K16/28 , A61K31/416 , A61K31/423 , A61K31/428 , A61K31/437 , A61K31/472 , A61K31/536 , A61K31/5415 , C07K14/72
CPC classification number: C12Q1/6886 , A61K31/416 , A61K31/4196 , A61K31/423 , A61K31/428 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/4439 , A61K31/472 , A61K31/536 , A61K31/5415 , A61K31/565 , A61K31/567 , A61K31/675 , A61K45/06 , C07K14/72 , C07K16/2869 , C07K2317/34 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156
Abstract: Novel mutant ESR1 molecules and uses are disclosed.
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公开(公告)号：US20180363066A1
公开(公告)日：2018-12-20
申请号：US16115373
申请日：2018-08-28
Applicant: Foundation Medicine, Inc. , Genentech, Inc.
Inventor： Zachary R. Chalmers , Caitlin F. Connelly , David Fabrizio , Garrett Michael Frampton , Priti Hegde , Marcin Kowanetz , Philip J. Stephens , James Xin Sun , Roman Yelensky
IPC: C12Q1/6886 , C12Q1/6806 , C12Q1/6827
Abstract: Methods of evaluating tumor mutational burden in a sample, e.g., a tumor sample or a sample derived from a tumor, from a subject, are disclosed.
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公开(公告)号：US09410954B2
公开(公告)日：2016-08-09
申请号：US14177615
申请日：2014-02-11
Applicant: FOUNDATION MEDICINE, INC. , UCL Business PLC
Inventor： Chris Hendrik Boshoff , Timothy Robert Fenton , Matthias Alexander Lechner , Philip James Stephens , Matthew J. Hawryluk , Garrett Michael Frampton , Roman Yelensky
IPC: A61K31/513 , A61K31/555 , A61K31/337 , A61K33/24 , G01N33/571 , C07K16/28 , C12Q1/68 , C12Q1/70 , A61K31/506 , A61K31/519 , A61K31/454 , A61K31/52 , A61K31/404 , A61K31/4196 , A61K31/282 , A61K39/395 , A61K31/436 , A61K31/05 , A61K31/4709 , A61K31/496 , A61K31/5377 , A61K31/352 , A61N5/00 , A61K31/366 , A61K31/505 , A61K31/439 , A61K31/4745 , A61K39/00
CPC classification number: A61K31/519 , A61K31/05 , A61K31/282 , A61K31/337 , A61K31/352 , A61K31/366 , A61K31/404 , A61K31/4196 , A61K31/436 , A61K31/439 , A61K31/454 , A61K31/4709 , A61K31/4745 , A61K31/496 , A61K31/505 , A61K31/506 , A61K31/513 , A61K31/52 , A61K31/5377 , A61K31/555 , A61K33/24 , A61K39/39558 , A61K2039/505 , A61N5/00 , A61N5/10 , C07K16/2863 , C12Q1/6883 , C12Q1/6886 , C12Q1/708 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16 , G01N33/571 , A61K2300/00
Abstract: Methods of treating a head and neck cancer are disclosed.
Abstract translation: 公开了治疗头颈癌的方法。
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公开(公告)号：US20150030587A1
公开(公告)日：2015-01-29
申请号：US14177615
申请日：2014-02-11
Applicant: Foundation Medicine, Inc.
Inventor： Chris Hendrik Boshoff , Timothy Robert Fenton , Matthias Alexander Lechner , Philip James Stephens , Matthew J. Hawryluk , Garrett Michael Frampton , Roman Yelensky
IPC: G01N33/571 , C07K16/28 , A61K31/513 , A61K31/555 , A61K31/337 , A61K31/366 , C12Q1/68 , A61K31/439 , A61K31/05 , A61K31/4745 , A61K31/496 , A61K31/5377 , A61K33/24 , C12Q1/70
CPC classification number: A61K31/519 , A61K31/05 , A61K31/282 , A61K31/337 , A61K31/352 , A61K31/366 , A61K31/404 , A61K31/4196 , A61K31/436 , A61K31/439 , A61K31/454 , A61K31/4709 , A61K31/4745 , A61K31/496 , A61K31/505 , A61K31/506 , A61K31/513 , A61K31/52 , A61K31/5377 , A61K31/555 , A61K33/24 , A61K39/39558 , A61K2039/505 , A61N5/00 , A61N5/10 , C07K16/2863 , C12Q1/6883 , C12Q1/6886 , C12Q1/708 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16 , G01N33/571 , A61K2300/00
Abstract: Methods of treating a head and neck cancer are disclosed.
Abstract translation: 公开了治疗头颈癌的方法。
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公开(公告)号：US20140221329A1
公开(公告)日：2014-08-07
申请号：US14251856
申请日：2014-04-14
Applicant: FOUNDATION MEDICINE, INC.
Inventor： Maureen T. Cronin , Garrett Michael Frampton , Doron Lipson , Vincent A. Miller , Gary Palmer , Jeffrey S. Ross , Philip James Stephens , Roman Yelensky
IPC: C12Q1/68 , A61K31/439 , A61K31/567
CPC classification number: C12Q1/6886 , A61K31/416 , A61K31/4196 , A61K31/423 , A61K31/428 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/4439 , A61K31/472 , A61K31/536 , A61K31/5415 , A61K31/565 , A61K31/567 , A61K31/675 , A61K45/06 , C07K14/72 , C07K16/2869 , C07K2317/34 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156
Abstract: Novel mutant ESR1 molecules and uses are disclosed.
Abstract translation: 公开了新型突变体ESR1分子和用途。
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Patent Agency Ranking
公开(公告)号：US12116638B2
公开(公告)日：2024-10-15
申请号：US17673718
申请日：2022-02-16
Applicant: Foundation Medicine, Inc.
Inventor： Maureen T. Cronin , Garrett Michael Frampton , Doron Lipson , Vincent A. Miller , Gary Palmer , Jeffrey S. Ross , Philip James Stephens , Roman Yelensky
IPC: C12Q1/6886 , A61K31/416 , A61K31/4196 , A61K31/423 , A61K31/428 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/4439 , A61K31/472 , A61K31/536 , A61K31/5415 , A61K31/565 , A61K31/567 , A61K31/675 , A61K45/06 , C07K14/72 , C07K16/28
CPC classification number: C12Q1/6886 , A61K31/416 , A61K31/4196 , A61K31/423 , A61K31/428 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/4439 , A61K31/472 , A61K31/536 , A61K31/5415 , A61K31/565 , A61K31/567 , A61K31/675 , A61K45/06 , C07K14/72 , C07K16/2869 , C07K2317/34 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156
Abstract: Novel mutant ESR1 molecules and uses are disclosed.
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公开(公告)号：US11766439B2
公开(公告)日：2023-09-26
申请号：US17344777
申请日：2021-06-10
Applicant: FOUNDATION MEDICINE, INC. , UCL BUSINESS LTD
Inventor： Chris Hendrik Boshoff , Timothy Robert Fenton , Matthias Alexander Lechner , Philip James Stephens , Matthew J. Hawryluk , Garrett Michael Frampton , Roman Yelensky
IPC: A61K31/55 , A61K38/00 , A61K31/519 , C12Q1/70 , A61K31/506 , A61K31/454 , A61K31/52 , A61K31/404 , A61K31/4196 , A61K31/282 , A61K31/337 , A61K31/513 , A61K39/395 , A61K31/436 , A61K31/05 , A61K31/4709 , A61K31/496 , A61K31/5377 , A61K31/352 , A61N5/00 , C12Q1/6886 , A61K31/366 , A61K31/505 , A61K31/555 , A61K33/243 , A61K33/24 , A61K31/439 , A61K31/4745 , C07K16/28 , C12Q1/6883 , G01N33/571 , A61N5/10 , A61K39/00
CPC classification number: A61K31/519 , A61K31/05 , A61K31/282 , A61K31/337 , A61K31/352 , A61K31/366 , A61K31/404 , A61K31/4196 , A61K31/436 , A61K31/439 , A61K31/454 , A61K31/4709 , A61K31/4745 , A61K31/496 , A61K31/505 , A61K31/506 , A61K31/513 , A61K31/52 , A61K31/5377 , A61K31/555 , A61K33/24 , A61K33/243 , A61K39/39558 , A61N5/00 , A61N5/10 , C07K16/2863 , C12Q1/6883 , C12Q1/6886 , C12Q1/708 , G01N33/571 , A61K2039/505 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16 , A61K31/404 , A61K2300/00 , A61K31/454 , A61K2300/00 , A61K31/506 , A61K2300/00 , A61K31/513 , A61K2300/00 , A61K31/519 , A61K2300/00 , A61K31/52 , A61K2300/00 , A61K33/24 , A61K2300/00 , A61K31/436 , A61K2300/00 , A61K31/05 , A61K2300/00 , A61K31/366 , A61K2300/00 , A61K31/505 , A61K2300/00 , A61K31/555 , A61K2300/00 , A61K31/337 , A61K2300/00 , A61K31/282 , A61K2300/00 , A61K31/4196 , A61K2300/00 , A61K31/4709 , A61K2300/00 , A61K31/496 , A61K2300/00 , A61K31/5377 , A61K2300/00 , A61K31/105 , A61K2300/00
Abstract: Methods of treating a head and neck cancer are disclosed.
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公开(公告)号：US20190085403A1
公开(公告)日：2019-03-21
申请号：US16080421
申请日：2017-02-27
Applicant: FOUNDATION MEDICINE, INC. , VANDERBILT UNIVERSITY
Inventor： Garrett Michael Frampton , Roman Yelensky , James Xin Sun , Douglas Buckner Johnson , Christine Marie Lovly , Jeffrey Alan Sosman
Abstract: Methods and compositions for treating cancer such as melanomas are disclosed.
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公开(公告)号：US20180338977A1
公开(公告)日：2018-11-29
申请号：US15873703
申请日：2018-01-17
Applicant: FOUNDATION MEDICINE, INC. , UCL Business PLC
Inventor： Chris Hendrik Boshoff , Timothy Robert Fenton , Matthias Alexander Lechner , Philip James Stephens , Matthew J. Hawryluk , Garrett Michael Frampton , Roman Yelensky
IPC: A61K31/519 , C12Q1/6886 , A61K31/496 , A61K31/4709 , A61K31/05 , A61K31/436 , A61K39/395 , A61K31/513 , A61K31/337 , A61K31/282 , A61K33/24 , A61K31/4196 , A61K31/404 , A61K31/52 , A61K31/454 , A61K31/506 , C12Q1/70 , A61N5/00 , A61K31/352 , A61N5/10 , G01N33/571 , A61K31/439 , A61K31/4745
Abstract: Methods of treating a head and neck cancer are disclosed.
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公开(公告)号：US20180320238A1
公开(公告)日：2018-11-08
申请号：US15877035
申请日：2018-01-22
Applicant: FOUNDATION MEDICINE, INC.
Inventor： Maureen T. Cronin , Garrett Michael Frampton , Doron Lipson , Vincent A. Miller , Gary Palmer , Jeffrey S. Ross , Philip James Stephens , Roman Yelensky
IPC: C12Q1/6886 , A61K31/675 , A61K31/565 , A61K31/436 , A61K31/4439 , C07K16/28 , A61K31/416 , A61K31/423 , A61K31/428 , A61K31/437 , A61K31/472 , A61K31/536 , A61K31/5415 , C07K14/72 , A61K31/567 , A61K45/06 , A61K31/439 , A61K31/4196
CPC classification number: C12Q1/6886 , A61K31/416 , A61K31/4196 , A61K31/423 , A61K31/428 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/4439 , A61K31/472 , A61K31/536 , A61K31/5415 , A61K31/565 , A61K31/567 , A61K31/675 , A61K45/06 , C07K14/72 , C07K16/2869 , C07K2317/34 , C12Q2600/106 , C12Q2600/118 , C12Q2600/156
Abstract: Novel mutant ESR1 molecules and uses are disclosed.
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