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11.Preparation of bicyclic enol-ethers, and novel ethers of 2-(3-hydroxyprop-l-yl)-cycloalkanones 失效
标题翻译: 双环烯醇醚的制备和2-(3-羟基丙-1-基) - 环烷酮的新型醚公开(公告)号:US4268445A
公开(公告)日:1981-05-19
申请号:US117128
申请日:1980-01-31
申请人: Rudolf Kropp , Frank Thoemel , Axel Nuerrenbach , Werner Hoffman , Franz Wenisch , Hartwig Fuchs
发明人: Rudolf Kropp , Frank Thoemel , Axel Nuerrenbach , Werner Hoffman , Franz Wenisch , Hartwig Fuchs
IPC分类号: C07C45/00 , C07C45/69 , C07C49/517 , C07C67/00 , C07D307/20 , C07D309/12 , C07D311/74 , C07D311/94 , C07D311/44
CPC分类号: C07D311/94 , C07C45/69 , C07C49/517 , C07D307/20 , C07D309/12 , C07D311/74
摘要: The preparation of bicyclic enol-ethers (I) ##STR1## (where n is from 3 to 12, and R.sup.1, R.sup.2 and R.sup.3 may be H or C.sub.1 --C.sub.4 -alkyl) by free radical adduct formation of CHR.sup.1 =CR.sup.2 --CHR.sup.3 --O--R.sup.4 (III)(where R.sup.4 is tert.-butyl, tetrahydrofuran-2-yl or tetrahydropyran-2-yl) with a cyclic ketone (IV) ##STR2## followed by acid-catalyzed cyclization, and novel compounds II ##STR3## The compounds (I) and (II) are intermediates for the synthesis of musk-like fragrances.
摘要翻译: 通过CHR1 = CR2的自由基加合物形成制备双环烯醇醚(I)(I)(其中n为3至12,R1,R2和R3可以是H或C1-C4-烷基) (IV)的化合物,其中R 4是叔丁基,四氢呋喃-2-基或四氢吡喃-2-基),然后酸催化环化, (II)化合物(I)和(II)是合成麝香香料的中间体。
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公开(公告)号:US5126371A
公开(公告)日:1992-06-30
申请号:US569869
申请日:1990-08-20
IPC分类号: C07D263/10 , A61K31/015 , A61K31/03 , A61K31/075 , A61K31/085 , A61K31/11 , A61K31/115 , A61K31/12 , A61K31/135 , A61K31/16 , A61K31/165 , A61K31/19 , A61K31/215 , A61K31/22 , A61K31/275 , A61K31/41 , A61P17/00 , A61P29/00 , A61P35/00 , C07C1/00 , C07C13/465 , C07C13/48 , C07C17/00 , C07C25/24 , C07C27/00 , C07C33/38 , C07C39/23 , C07C39/38 , C07C43/168 , C07C43/176 , C07C43/215 , C07C43/23 , C07C45/00 , C07C45/44 , C07C45/68 , C07C47/548 , C07C47/55 , C07C47/57 , C07C47/575 , C07C49/683 , C07C49/747 , C07C49/757 , C07C49/798 , C07C49/813 , C07C49/835 , C07C49/84 , C07C57/50 , C07C57/62 , C07C59/72 , C07C63/66 , C07C63/74 , C07C65/19 , C07C65/28 , C07C65/38 , C07C67/00 , C07C69/618 , C07C69/65 , C07C69/734 , C07C69/76 , C07C69/78 , C07C209/00 , C07C209/48 , C07C211/44 , C07C211/52 , C07C215/74 , C07C233/05 , C07C233/11 , C07C233/22 , C07C233/29 , C07C233/65 , C07C235/34 , C07C235/38 , C07C235/42 , C07C255/50 , C07C255/51 , C07C255/54 , C07C255/56 , C07D257/04
CPC分类号: C07D257/04 , C07C255/00 , C07C33/38 , C07C43/168 , C07C43/215 , C07C45/44 , C07C45/68 , C07C47/548 , C07C47/57 , C07C47/575 , C07C49/683 , C07C49/747 , C07C49/757 , C07C49/798 , C07C49/835 , C07C49/84 , C07C57/50 , C07C63/66 , C07C63/74 , C07C65/19 , C07C65/28 , C07C65/38
摘要: Novel diarylacetylenes of the formula I ##STR1## where A, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 have the meanings stated in the description, are useful for the treatment of disorders.
摘要翻译: 式I的新型二芳基乙炔,其中A,R1,R2,R3,R4,R5和R6具有说明书中所述的含义,可用于治疗疾病。
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公开(公告)号:US4806558A
公开(公告)日:1989-02-21
申请号:US778256
申请日:1985-09-20
IPC分类号: C07D263/10 , A61K31/015 , A61K31/03 , A61K31/075 , A61K31/085 , A61K31/11 , A61K31/115 , A61K31/12 , A61K31/135 , A61K31/16 , A61K31/165 , A61K31/19 , A61K31/215 , A61K31/22 , A61K31/275 , A61K31/41 , A61P17/00 , A61P29/00 , A61P35/00 , C07C1/00 , C07C13/465 , C07C13/48 , C07C17/00 , C07C25/24 , C07C27/00 , C07C33/38 , C07C39/23 , C07C39/38 , C07C43/168 , C07C43/176 , C07C43/215 , C07C43/23 , C07C45/00 , C07C45/44 , C07C45/68 , C07C47/548 , C07C47/55 , C07C47/57 , C07C47/575 , C07C49/683 , C07C49/747 , C07C49/757 , C07C49/798 , C07C49/813 , C07C49/835 , C07C49/84 , C07C57/50 , C07C57/62 , C07C59/72 , C07C63/66 , C07C63/74 , C07C65/19 , C07C65/28 , C07C65/38 , C07C67/00 , C07C69/618 , C07C69/65 , C07C69/734 , C07C69/76 , C07C69/78 , C07C209/00 , C07C209/48 , C07C211/44 , C07C211/52 , C07C215/74 , C07C233/05 , C07C233/11 , C07C233/22 , C07C233/29 , C07C233/65 , C07C235/34 , C07C235/38 , C07C235/42 , C07C255/50 , C07C255/51 , C07C255/54 , C07C255/56 , C07D257/04 , A61K31/195 , C07C63/331
CPC分类号: C07D257/04 , C07C255/00 , C07C33/38 , C07C43/168 , C07C43/215 , C07C45/44 , C07C45/68 , C07C47/548 , C07C47/57 , C07C47/575 , C07C49/683 , C07C49/747 , C07C49/757 , C07C49/798 , C07C49/835 , C07C49/84 , C07C57/50 , C07C63/66 , C07C63/74 , C07C65/19 , C07C65/28 , C07C65/38
摘要: Novel diarylacetylenes of the formula I ##STR1## where A, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 have the meanings stated in the description, are useful for the treatment of dermatological disorders.
摘要翻译: 式I的新型二芳基乙炔,其中A,R1,R2,R3,R4,R5和R6具有说明书中所述的含义,可用于治疗皮肤病。
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14.
公开(公告)号:US4801733A
公开(公告)日:1989-01-31
申请号:US778681
申请日:1985-09-23
IPC分类号: C07D233/58 , A61K31/015 , A61K31/025 , A61K31/05 , A61K31/075 , A61K31/12 , A61K31/135 , A61K31/165 , A61K31/19 , A61K31/215 , A61K31/22 , A61K31/275 , A61K31/41 , A61K31/415 , A61K31/445 , A61K31/655 , A61P17/00 , A61P29/00 , A61P35/00 , C07C1/00 , C07C13/48 , C07C17/00 , C07C25/24 , C07C27/00 , C07C33/38 , C07C39/23 , C07C43/14 , C07C43/20 , C07C43/215 , C07C43/23 , C07C43/30 , C07C45/00 , C07C45/44 , C07C45/71 , C07C47/238 , C07C47/27 , C07C47/273 , C07C47/277 , C07C47/548 , C07C47/57 , C07C47/575 , C07C49/225 , C07C49/237 , C07C49/255 , C07C49/798 , C07C49/813 , C07C49/835 , C07C49/84 , C07C57/50 , C07C57/74 , C07C59/54 , C07C65/19 , C07C65/28 , C07C67/00 , C07C69/618 , C07C209/00 , C07C233/11 , C07C235/34 , C07C235/38 , C07C241/00 , C07C247/22 , C07C247/24 , C07C255/34 , C07C255/37 , C07C255/50 , C07C255/53 , C07C255/54 , C07D257/04 , C07D263/06 , C07D277/24 , C07D295/10 , C07C69/76
CPC分类号: C07C255/00 , C07C247/24 , C07C43/215 , C07C43/23 , C07C45/44 , C07C45/71 , C07C47/238 , C07C47/27 , C07C47/273 , C07C47/277 , C07C47/548 , C07C47/57 , C07C47/575 , C07C49/225 , C07C49/237 , C07C49/255 , C07C49/798 , C07C49/813 , C07C49/835 , C07C49/84 , C07C57/50 , C07C65/19 , C07C65/28 , C07C2102/10
摘要: 1-substituted tetralins of the formula I ##STR1## where n, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 have the meanings stated in the description, and their preparation are described. The compounds are useful for the treatment of disorders.
摘要翻译: 其中n,R1,R2,R3,R4,R5和R6具有说明书中所述的含义及其制备方法。 该化合物可用于治疗疾病。
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公开(公告)号:US4760174A
公开(公告)日:1988-07-26
申请号:US778190
申请日:1985-09-20
IPC分类号: C07C43/20 , A61K31/015 , A61K31/045 , A61K31/075 , A61K31/11 , A61K31/12 , A61K31/135 , A61K31/165 , A61K31/19 , A61K31/22 , A61K31/235 , A61K31/275 , A61K31/335 , A61K31/357 , A61K31/41 , A61K31/445 , A61K31/655 , A61P17/00 , A61P29/00 , A61P35/00 , C07C1/00 , C07C13/47 , C07C17/00 , C07C17/26 , C07C25/00 , C07C25/24 , C07C27/00 , C07C35/36 , C07C41/00 , C07C43/188 , C07C43/192 , C07C43/307 , C07C45/00 , C07C45/44 , C07C45/46 , C07C47/548 , C07C47/55 , C07C47/57 , C07C47/575 , C07C49/225 , C07C49/237 , C07C49/683 , C07C49/697 , C07C49/747 , C07C49/757 , C07C49/792 , C07C49/798 , C07C49/813 , C07C49/835 , C07C49/84 , C07C63/66 , C07C65/19 , C07C65/38 , C07C67/00 , C07C69/013 , C07C69/76 , C07C209/00 , C07C235/42 , C07C235/84 , C07C241/00 , C07C247/24 , C07C253/00 , C07C255/50 , C07C255/53 , C07C255/56 , C07D295/04 , C07D317/70 , C07C59/76
CPC分类号: C07C255/00 , C07C247/24 , C07C35/36 , C07C45/44 , C07C45/46 , C07C47/548 , C07C47/57 , C07C47/575 , C07C49/683 , C07C49/697 , C07C49/747 , C07C49/757 , C07C49/792 , C07C49/798 , C07C49/813 , C07C49/835 , C07C49/84 , C07C63/66 , C07C65/19 , C07C65/38 , C07C2102/10
摘要: Tetralin derivatives of the formula I ##STR1## where X, R.sup.1, R.sup.2 and R.sup.3 have the meanings stated in the description, and their preparation are described. The novel compounds are useful for the treatment of disorders.
摘要翻译: 其中X,R 1,R 2和R 3具有说明书中所述的含义及其制备方法描述了式I的四氢萘衍生物(I)。 新型化合物可用于治疗疾病。
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16.Mixtures which promote growth and increase production, and feeds and drinking liquids which contain small amounts of these mixtures 失效
标题翻译: 促进生长和增加生产的混合物,以及含有少量这些混合物的饲料和饮用液体公开(公告)号:US4616016A
公开(公告)日:1986-10-07
申请号:US597664
申请日:1984-04-06
申请人: Peter Lechtken , Axel Nuerrenbach , Walter Kohler , Peter P. Hoppe , Hubert Tiefenbacher , Juergen Schole
发明人: Peter Lechtken , Axel Nuerrenbach , Walter Kohler , Peter P. Hoppe , Hubert Tiefenbacher , Juergen Schole
IPC分类号: A23K1/16 , A23K1/18 , A61K9/40 , A61K31/47 , A61K31/495 , A61P3/00 , C07D215/58 , C07D265/36 , A61K31/50 , A61K31/535
CPC分类号: C07D265/36 , A23K20/105 , A23K20/126 , A23K20/132 , A23K20/137 , A23K20/142 , A23K50/30 , C07D215/58
摘要: A growth-promoting additive for feeds consists of a commercial growth promoter as well as an aminoreductone of the formula ##STR1## where R.sup.1, R.sup.2 and R.sup.3 are each hydrogen, methyl or ethyl and R.sup.4 is an unsubstituted or substituted C.sub.1 -C.sub.20 -alkyl or alkenyl radical or a radical of an aminoacid.
摘要翻译: 用于饲料的生长促进添加剂由商业生长促进剂以及式I的氨基还原酮组成,其中R 1,R 2和R 3各自为氢,甲基或乙基,R 4为未取代或取代的C 1 -C 20 - 烷基 或烯基或氨基酸的基团。
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