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公开(公告)号：US08617559B2
公开(公告)日：2013-12-31
申请号：US13682581
申请日：2012-11-20
Applicant: Genentech, Inc.
Inventor： Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: A61K39/00
CPC classification number: G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US20200222545A1
公开(公告)日：2020-07-16
申请号：US16827083
申请日：2020-03-23
Applicant: Genentech, Inc.
Inventor： Thomas Pillow , Andrew G. Polson , Bing Zheng
IPC: A61K47/54 , C07K19/00 , C07D407/12 , A61K45/06 , A61K47/68 , A61K31/357 , G01N33/567
Abstract: The invention relates generally to a silvestrol molecule activated with a leaving group. The invention further relates generally to an antibody-drug conjugate comprising an antibody conjugated by a linker to one or more silvestrol drug moieties and methods of treatment.
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公开(公告)号：US10544218B2
公开(公告)日：2020-01-28
申请号：US15349964
申请日：2016-11-11
Applicant: Genentech, Inc.
Inventor： Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: A61K39/395 , A61K39/40 , A61K39/42 , C07K16/28 , A61K38/05 , A61K31/537 , C07K16/30 , A61K51/10 , G01N33/574 , A61K45/06 , A61K47/68 , C07K16/00 , C12P21/08 , A61K39/00
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20190276550A9
公开(公告)日：2019-09-12
申请号：US13973669
申请日：2013-08-22
Applicant: Genentech, Inc.
Inventor： Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: C07K16/28 , A61K39/395 , A61K45/06
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US20180009894A1
公开(公告)日：2018-01-11
申请号：US15657472
申请日：2017-07-24
Applicant: Genentech, Inc.
Inventor： Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: C07K16/28 , C07K16/30 , A61K31/706 , A61K51/10 , G01N33/574 , A61K31/5517
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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Patent Agency Ranking
公开(公告)号：US20140099260A1
公开(公告)日：2014-04-10
申请号：US13973669
申请日：2013-08-22
Applicant: Genentech, Inc.
Inventor： Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: C07K16/28 , A61K45/06 , A61K39/395
CPC classification number: C07K16/2803 , A61K31/537 , A61K38/05 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6811 , A61K47/6849 , A61K47/6867 , A61K51/1027 , A61K2039/505 , C07K16/2896 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , G01N33/57492 , Y02A50/412 , Y02A50/423
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US20140030282A1
公开(公告)日：2014-01-30
申请号：US13936285
申请日：2013-07-08
Applicant: Genentech, Inc.
Inventor： Paul Polakis , Andrew Polson , Susan Diane Spencer , Shang-Fan Yu , Bing Zheng
IPC: A61K47/48 , A61K45/06 , A61K31/706
CPC classification number: A61K47/6809 , A61K31/706 , A61K45/06 , A61K47/6849 , A61K47/6851 , A61K47/6867
Abstract: The invention provides anti-CD79b antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗CD79b抗体和免疫缀合物及其使用方法。
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公开(公告)号：US11866496B2
公开(公告)日：2024-01-09
申请号：US17234695
申请日：2021-04-19
Applicant: Genentech, Inc.
Inventor： Yvonne Chen , Mark Dennis , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
CPC classification number: C07K16/2803 , A61K39/39541 , A61K39/39558 , A61K47/6849 , A61K51/1027 , C07K16/2896 , C07K16/3061 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/92 , Y02A50/30
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：US09896506B2
公开(公告)日：2018-02-20
申请号：US14734957
申请日：2015-06-09
Applicant: Genentech, Inc.
Inventor： Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K47/68 , A61K38/05 , A61K45/06 , A61K51/10 , G01N33/574 , A61K31/537 , A61K39/00
CPC classification number: C07K16/2803 , A61K31/537 , A61K38/05 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6811 , A61K47/6849 , A61K47/6867 , A61K51/1027 , A61K2039/505 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , G01N33/57492 , Y02A50/412 , Y02A50/423
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals, including immunoconjugates comprising anti-CD79b cysteine-engineered antibody huMA79b.v28, and to methods of using those compositions of matter for the same.
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公开(公告)号：US20180044421A1
公开(公告)日：2018-02-15
申请号：US15657476
申请日：2017-07-24
Applicant: Genentech, Inc.
Inventor： Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: C07K16/28 , A61K47/68 , A61K51/10 , A61K31/706 , G01N33/574 , C07K16/30 , A61K31/5517
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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