-
公开(公告)号：US20180161307A1
公开(公告)日：2018-06-14
申请号：US15686499
申请日：2017-08-25
Applicant: Gilead Sciences, Inc.
Inventor： Jinfa Du , Joshua A. Kaplan , Thorsten A. Kirschberg , Tetsuya Kobayashi , Scott E. Lazerwith , Rick Andrew Lee , Jonathan William Medley , Michael L. Mitchell , Philip Anthony Morganelli , Hyung-Jung Pyun , Sophia L. Shevick , Neil H. Squires , William J. Watkins
IPC: A61K31/403 , A61K31/16 , A61K31/03 , A61K31/38 , A61K31/4192 , A61P31/20
CPC classification number: A61K31/403 , A61K31/03 , A61K31/16 , A61K31/38 , A61K31/4192 , A61P31/20 , C07D487/04 , C07D519/00
Abstract: This application relates generally to certain substituted pyrrolizine compounds, and pharmaceutical compositions which inhibit HBV replication, and methods of making and using them.
-
公开(公告)号：US12161625B2
公开(公告)日：2024-12-10
申请号：US18059806
申请日：2022-11-29
Applicant: Gilead Sciences, Inc.
Inventor： Jinfa Du , Joshua A. Kaplan , Thorsten A. Kirschberg , Tetsuya Kobayashi , Scott E. Lazerwith , Rick Andrew Lee , Jonathan William Medley , Michael L. Mitchell , Philip Anthony Morganelli , Hyung-Jung Pyun , Sophia L. Shevick , Neil H. Squires , William J. Watkins
IPC: A61K31/403 , A61K31/03 , A61K31/16 , A61K31/38 , A61K31/4192 , A61P31/20 , C07D487/04 , C07D519/00
Abstract: This application relates generally to certain substituted pyrrolizine compounds, and pharmaceutical compositions which inhibit HBV replication, and methods of making and using them.
-
公开(公告)号：US20230303599A1
公开(公告)日：2023-09-28
申请号：US18040782
申请日：2021-08-05
Applicant: Gilead Sciences, Inc.
Inventor： Daniel H. Byun , Byoung-Kwon Chun , Michael O. Clarke , Petr Jansa , Devan Naduthambi , Neil H. Squires
IPC: C07F9/6561 , A61K45/06 , A61P31/18 , A61P31/20
CPC classification number: C07F9/65616 , A61K45/06 , A61P31/18 , A61P31/20
Abstract: Compounds, compositions, and method useful for treating a viral infection, such as human immunodeficiency virus (HIV) and/or hepatitis B virus (HBV) infection, are disclosed. In particular, prodrugs of phosphonamide nucleotide analogues and methods for their preparation and use as therapeutic or prophylactic agents are disclosed.
-
公开(公告)号：US11555029B2
公开(公告)日：2023-01-17
申请号：US16891880
申请日：2020-06-03
Applicant: Gilead Sciences, Inc.
Inventor： Evangelos Aktoudianakis , Aesop Cho , Zhimin Du , Michael Graupe , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Prasenjit Kumar Mukherjee , Devan Naduthambi , Eric Q. Parkhill , Barton W. Phillips , Scott Preston Simonovich , Neil H. Squires , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC: C07D403/14 , A61P31/20 , A61P35/02 , A61K31/496 , C07D519/00 , C07D241/20 , C07D487/10 , C07D405/14 , C07D487/08 , A61K31/497 , C07D491/107 , C07D241/18 , A61P35/00 , C07K16/28
Abstract: Compounds of Formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
-
公开(公告)号：US20220340535A1
公开(公告)日：2022-10-27
申请号：US17171201
申请日：2021-02-09
Applicant: Gilead Sciences, Inc.
Inventor： Hang Chu , Juan A. Guerrero , Anna E. Hurtley , Tae H. Hwang , Lan Jiang , Darryl Kato , Tetsuya Kobayashi , John E. Knox , Scott E. Lazerwith , Xiaofen Li , David W. Lin , Jonathan W. Medley , Michael L. Mitchell , Devan Naduthambi , Zachary Newby , Neil H. Squires , Vickie H. Tsui , Chandrasekar Venkataramani , William J. Watkins , Hong Yang
IPC: C07D267/20 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04 , C07D498/04
Abstract: The present disclosure generally relates to compounds and pharmaceutical compositions that may be used in methods of treating cancer.
-
Patent Agency Ranking
公开(公告)号：US20210053946A1
公开(公告)日：2021-02-25
申请号：US16891880
申请日：2020-06-03
Applicant: Gilead Sciences, Inc.
Inventor： Evangelos Aktoudianakis , Aesop Cho , Zhimin Du , Michael Graupe , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Prasenjit Kumar Mukherjee , Devan Naduthambi , Eric Q. Parkhill , Barton W. Phillips , Scott Preston Simonovich , Neil H. Squires , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC: C07D403/14 , A61P31/20 , A61P35/02 , A61K31/496 , C07D519/00 , C07D241/20 , C07D487/10 , C07D405/14 , C07D487/08 , A61K31/497 , C07D491/107 , C07D241/18 , A61P35/00
Abstract: Compounds of Formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
-
公开(公告)号：US10899735B2
公开(公告)日：2021-01-26
申请号：US16388517
申请日：2019-04-18
Applicant: Gilead Sciences, Inc
Inventor： Evangelos Aktoudianakis , Aesop Cho , Zhimin Du , Michael Graupe , Lateshkumar Thakorlal Lad , Paulo A. Machicao Tello , Jonathan William Medley , Samuel E. Metobo , Prasenjit Kumar Mukherjee , Devan Naduthambi , Eric Q. Parkhill , Barton W. Phillips , Scott Preston Simonovich , Neil H. Squires , Peiyuan Wang , William J. Watkins , Jie Xu , Kin Shing Yang , Christopher Allen Ziebenhaus
IPC: C07D401/10 , A61K31/444 , C07D401/04 , C07D401/12 , C07D401/14 , C07D487/10 , C07D519/00 , C07K16/28
Abstract: Compounds and methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
-
公开(公告)号：US10316017B2
公开(公告)日：2019-06-11
申请号：US15697755
申请日：2017-09-07
Applicant: Gilead Sciences, Inc.
Inventor： Elizabeth M. Bacon , Gayatri Balan , Chien-Hung Chou , Christopher T. Clark , Jeromy J. Cottell , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Scott D. Schroeder , Neil H. Squires , Kirk L. Stevens , James G. Taylor , William J. Watkins , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D401/12 , C07D453/02 , C07D417/14 , C07D413/14 , C07D413/12 , C07D409/14 , C07D405/14 , C07D401/14 , C07F7/08
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
-
公开(公告)号：US20180002316A1
公开(公告)日：2018-01-04
申请号：US15634314
申请日：2017-06-27
Applicant: Gilead Sciences, Inc.
Inventor： Gayatri Balan , Chien-Hung Chou , Musong Kim , Thorsten A. Kirschberg , John O. Link , Gary Phillips , Roland D. Saito , Neil H. Squires , James G. Taylor , William J. Watkins , Nathan E. Wright
IPC: C07D403/12 , C07D401/14 , C07D405/14 , C07D417/14
CPC classification number: C07D403/12 , C07D401/14 , C07D405/14 , C07D417/14
Abstract: The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof.
-
公开(公告)号：US12110305B2
公开(公告)日：2024-10-08
申请号：US17394630
申请日：2021-08-05
Applicant: Gilead Sciences, Inc.
Inventor： Daniel H. Byun , Byoung-Kwon Chun , Michael O. Clarke , Petr Jansa , Devan Naduthambi , Neil H. Squires
IPC: C07F9/36 , A61K45/06 , A61P31/18 , A61P31/20 , C07F9/6561
CPC classification number: C07F9/36 , A61K45/06 , A61P31/18 , A61P31/20 , C07F9/65616
Abstract: Compounds, compositions, and method useful for treating a viral infection, such as human immunodeficiency virus (HIV) and/or hepatitis B virus (HBV) infection, are disclosed. In particular, prodrugs of phosphonamide nucleotide analogues and methods for their preparation and use as therapeutic or prophylactic agents are disclosed.
-
-
-
-
-
-
-
-
-
Search Results
45
records
(took 0.039 seconds)
