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11.发明授权Fermentative production of acetone from renewable resources by means of novel metabolic pathway 有权通过新型代谢途径从可再生资源中发酵生产丙酮公开(公告)号：US08986961B2
公开(公告)日：2015-03-24
申请号：US12679488
申请日：2008-10-01
申请人： Stefan Verseck , Steffen Schaffer , Werner Freitag , Friedrich-Georg Schmidt , Matthias Orschel , Gerda Grund , Wilfried Schmidt , Hubert Johannes Bahl , Ralf-Joerg Fischer , Antje May , Peter Duerre , Simone Lederle
发明人： Stefan Verseck , Steffen Schaffer , Werner Freitag , Friedrich-Georg Schmidt , Matthias Orschel , Gerda Grund , Wilfried Schmidt , Hubert Johannes Bahl , Ralf-Joerg Fischer , Antje May , Peter Duerre , Simone Lederle
CPC分类号： C12P7/28 , C12N9/16 , C12N9/93 , C12Y301/02 , C12Y301/02018
摘要： The invention describes a process for preparing acetone starting from acetyl-coenzyme A comprising process steps A. enzymatic conversion of acetyl-CoA into acetoacetyl-CoA B. enzymatic conversion of acetoacetyl-CoA into acetoacetate and CoA and C. decarboxylation of acetoacetate to acetone and CO2, which is characterized in that the coenzyme A is not transferred in process step B to an acceptor molecule. In addition, process step B is surprisingly catalyzed by enzymes of the classes of acyl-CoA thioesterase, acyl-CoA synthetase or acyl-CoA thiokinase.A completely novel metabolic pathway is concerned, because the enzymatic hydrolysis of acetoacetyl-CoA without simultaneous transfer of CoA to a receptor molecule has never previously been described for any microbial enzyme.
摘要翻译： 本发明描述了从乙酰辅酶A开始制备丙酮的方法，包括方法步骤A.将乙酰辅酶A酶促转化为乙酰乙酰辅酶A.将乙酰乙酰辅酶A酶促转化为乙酰乙酸酯，并将乙酰乙酸酯脱羧至丙酮， CO 2，其特征在于辅酶A在工艺步骤B中不转移到受体分子。 此外，方法步骤B令人惊奇地由酰基-CoA硫酯酶，酰基辅酶A合成酶或酰基辅酶A硫代激酶类的酶催化。 关注一个完全新颖的代谢途径，因为乙酰乙酰辅酶A的酶水解而不会同时转移CoA到受体分子，从未以前没有描述任何微生物酶。
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公开(公告)号：US20140021141A1
公开(公告)日：2014-01-23
申请号：US13795271
申请日：2013-03-12
申请人： Gerda Grund , Johannes Chiovaro , Hartmut Rahtz , Karsten Hoeland
发明人： Gerda Grund , Johannes Chiovaro , Hartmut Rahtz , Karsten Hoeland
IPC分类号： C02F1/76
CPC分类号： C02F1/76 , B01F3/0446 , B01F3/0865 , B01F2003/04907 , C01B11/022 , C02F1/685
摘要： An arrangement for addition of chlorine dioxide to flowing water in a pipeline is provided. The reactants are reacted in a reaction chamber located in the flow of water and the chlorine dioxide is passed from the reaction chamber directly into the flowing water.
摘要翻译： 提供了一种用于向管道中的流水添加二氧化氯的装置。 反应物在位于水流中的反应室中反应，二氧化氯直接从反应室通入流动的水中。
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公开(公告)号：US20120101304A1
公开(公告)日：2012-04-26
申请号：US13260012
申请日：2010-02-23
申请人： Franz Ulrich Becker , Gerda Grund , Matthias Orschel , Kai Doderer , Gerd Löhden , Gerd Brand , Peter Dürre , Simone Thum , Hubert Johannes Bahl , Ralf-Jörg Fischer , Antje May
发明人： Franz Ulrich Becker , Gerda Grund , Matthias Orschel , Kai Doderer , Gerd Löhden , Gerd Brand , Peter Dürre , Simone Thum , Hubert Johannes Bahl , Ralf-Jörg Fischer , Antje May
CPC分类号： C12N9/13 , C12N9/1029 , C12N9/16 , C12N9/88 , C12P7/30 , C12Y203/01009 , Y02P20/52
摘要： The invention relates to cells and a method for producing acetone.
摘要翻译： 本发明涉及细胞和生产丙酮的方法。
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14.发明授权Apparatus and process for the continuous reaction of a liquid with a gas over a solid catalyst 有权液体与固体催化剂上的气体连续反应的装置和方法公开(公告)号：US07611683B2
公开(公告)日：2009-11-03
申请号：US11117335
申请日：2005-04-29
申请人： Gerda Grund , Stefan Jelko , Wilfried Büschken , Udo Peters
发明人： Gerda Grund , Stefan Jelko , Wilfried Büschken , Udo Peters
CPC分类号： B01J8/0278 , B01J2208/00849
摘要： A reactor, which is capable of accommodating a reaction in which at least three phases are present and at least one gaseous starting material and at least one liquid starting material are reacted in cocurrent over a fixed-bed catalyst to give one or more product(s), contains at least one first zone in which a catalyst is present as a fixed bed; and at least one second zone whose size corresponds to a reactor cross section and which is separated from the at least one first zone by a distributor plate provided with at least one hole and in which at least one liquid and at least one gaseous starting material enter the reactor. The distributor plate is provided with at least one static mixer which is located in the at least one hole on at least one side of the distributor plate.
摘要翻译： 能够容纳存在至少三相的反应的反应器和至少一种气态原料和至少一种液体原料在固定床催化剂上并流反应，得到一种或多种产物 ）包含至少一个作为固定床存在催化剂的第一区域; 以及至少一个第二区，其尺寸对应于反应器横截面，并且通过设置有至少一个孔的分配器板与所述至少一个第一区分开，并且其中至少一个液体和至少一种气态原料进入 反应堆。 分配板设有至少一个静态混合器，其位于分配器板的至少一侧上的至少一个孔中。
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15.发明申请Apparatus and process for the continuous reaction of a liquid with a gas over a solid catalyst 有权液体与固体催化剂上的气体连续反应的装置和方法公开(公告)号：US20050256281A1
公开(公告)日：2005-11-17
申请号：US11117335
申请日：2005-04-29
申请人： Gerda Grund , Stefan Jelko , Wilfried Buschken , Udo Peters
发明人： Gerda Grund , Stefan Jelko , Wilfried Buschken , Udo Peters
IPC分类号： B01F3/04 , B01F5/00 , B01J8/00 , B01J8/02 , C07B61/00 , C07C5/05 , C07C11/08 , C07C45/00 , C08F2/00
CPC分类号： B01J8/0278 , B01J2208/00849
摘要： A reactor, which is capable of accommodating a reaction in which at least three phases are present and at least one gaseous starting material and at least one liquid starting material are reacted in cocurrent over a fixed-bed catalyst to give one or more product(s), contains at least one first zone in which a catalyst is present as a fixed bed; and at least one second zone whose size corresponds to a reactor cross section and which is separated from the at least one first zone by a distributor plate provided with at least one hole and in which at least one liquid and at least one gaseous starting material enter the reactor. The distributor plate is provided with at least one static mixer which is located in the at least one hole on at least one side of the distributor plate.
摘要翻译： 能够容纳存在至少三相的反应的反应器和至少一种气态原料和至少一种液体原料在固定床催化剂上并流反应，得到一种或多种产物 ）包含至少一个作为固定床存在催化剂的第一区域; 以及至少一个第二区，其尺寸对应于反应器横截面，并且通过设置有至少一个孔的分配器板与所述至少一个第一区分开，并且其中至少一个液体和至少一种气态原料进入 反应堆。 分配板设有至少一个静态混合器，其位于分配器板的至少一侧上的至少一个孔中。
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公开(公告)号：US09453210B2
公开(公告)日：2016-09-27
申请号：US13260012
申请日：2010-02-23
申请人： Franz Ulrich Becker , Gerda Grund , Matthias Orschel , Kai Doderer , Gerd Loehden , Gerd Brand , Peter Duerre , Simone Thum , Hubert Johannes Bahl , Ralf-Joerg Fischer , Antje May
发明人： Franz Ulrich Becker , Gerda Grund , Matthias Orschel , Kai Doderer , Gerd Loehden , Gerd Brand , Peter Duerre , Simone Thum , Hubert Johannes Bahl , Ralf-Joerg Fischer , Antje May
CPC分类号： C12N9/13 , C12N9/1029 , C12N9/16 , C12N9/88 , C12P7/30 , C12Y203/01009 , Y02P20/52
摘要： The invention relates to cells and a method for producing acetone.
摘要翻译： 本发明涉及细胞和生产丙酮的方法。
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公开(公告)号：US09187412B2
公开(公告)日：2015-11-17
申请号：US14124449
申请日：2012-06-05
IPC分类号： C07C253/10 , C07C253/30
CPC分类号： C07C253/30 , C07C253/10 , C07C2601/14 , C07C255/46
摘要： The present invention refers to the preparation of 3-cyano-3,5,5-trimethylcyclohexanone (isophorone nitrile, abbreviation IPN) using a calcium alkoxide, particularly calcium ethoxide, as catalyst.
摘要翻译： 本发明涉及使用烷氧基化钙，特别是乙醇钙作为催化剂制备3-氰基-3,5,5-三甲基环己酮（异佛尔酮腈，缩写IPN）。
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公开(公告)号：US09156717B2
公开(公告)日：2015-10-13
申请号：US13795271
申请日：2013-03-12
申请人： Gerda Grund , Johannes Chiovaro , Hartmut Rahtz , Karsten Hoeland
发明人： Gerda Grund , Johannes Chiovaro , Hartmut Rahtz , Karsten Hoeland
CPC分类号： C02F1/76 , B01F3/0446 , B01F3/0865 , B01F2003/04907 , C01B11/022 , C02F1/685
摘要： An arrangement for addition of chlorine dioxide to flowing water in a pipeline is provided. The reactants are reacted in a reaction chamber located in the flow of water and the chlorine dioxide is passed from the reaction chamber directly into the flowing water.
摘要翻译： 提供了一种用于向管道中的流水添加二氧化氯的装置。 反应物在位于水流中的反应室中反应，二氧化氯直接从反应室通入流动的水中。
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公开(公告)号：US20140114085A1
公开(公告)日：2014-04-24
申请号：US14124449
申请日：2012-06-05
IPC分类号： C07C253/30
CPC分类号： C07C253/30 , C07C253/10 , C07C2601/14 , C07C255/46
摘要： The present invention refers to the preparation of 3-cyano-3,5,5-trimethylcyclohexanone (isophorone nitrile, abbreviation IPN) using a calcium alkoxide, particularly calcium ethoxide, as catalyst.
摘要翻译： 本发明涉及使用烷氧基化钙，特别是乙醇钙作为催化剂制备3-氰基-3,5,5-三甲基环己酮（异佛尔酮腈，缩写IPN）。
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20.发明申请公开(公告)号：US20140113341A1
公开(公告)日：2014-04-24
申请号：US14124486
申请日：2012-06-13
CPC分类号： C12P7/06 , B01D53/1487 , B01D53/1493 , B01D2252/205 , B01D2257/708 , C07C45/783 , C07C45/80 , C07C45/82 , C12P7/065 , C12P7/16 , C12P7/28 , Y02E50/10 , Y02E50/17 , C07C49/08
摘要： The invention relates to a method comprising the following method steps: A) providing an aqueous solution comprising microorganisms producing low-molecular, organic compounds; B) introducing at least one gas or gas mixture into the aqueous solution; C) recovering the gas flow through a compound comprising an isophoron; and optionally D) separating the low-molecular, organic compound from the composition comprising the isophoron.
摘要翻译： 本发明涉及包括以下方法步骤的方法：A）提供包含产生低分子有机化合物的微生物的水溶液; B）将至少一种气体或气体混合物引入该水溶液中; C）回收通过包含异佛尔酮的化合物的气流; 和任选地D）从包含异佛尔酮的组合物中分离出低分子有机化合物。
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